The title compound (C20H15ClN4O, Mr = 362.81) was synthesized by the reaction of ethyl 2-cyano-3-(2-chlorophenyl)-1-acylate with 5-amino-3-methyl-1-phenylpyrazole under microwave irradiation and its structure was dete...The title compound (C20H15ClN4O, Mr = 362.81) was synthesized by the reaction of ethyl 2-cyano-3-(2-chlorophenyl)-1-acylate with 5-amino-3-methyl-1-phenylpyrazole under microwave irradiation and its structure was determined by single-crystal X-ray diffraction. The crystal is of monoclinic, space group P21/n with a = 8.8192(19), b = 15.976(3), c = 13.094(3) ? = 103.074(4), V = 1797.1(7) ?, Z = 4, Dc = 1.341 g/cm3, = 0.229 mm-1, F(000) = 752, R = 0.0632 and wR = 0.1278. X-ray analysis reveals that the pyridine ring adopts an envelope conformation. The dihedral angle between the pyrazole and pyridine planes is 2.19, and inter- molecular hydrogen bonds are also observed in the molecule.展开更多
Three ruthenium(II)complex catalysts bearing2,6‐bis(tetrazolyl)pyridine were synthesized,structurally characterized,and applied in the transfer hydrogenation of ketones.Their different catalytic activities were attri...Three ruthenium(II)complex catalysts bearing2,6‐bis(tetrazolyl)pyridine were synthesized,structurally characterized,and applied in the transfer hydrogenation of ketones.Their different catalytic activities were attributed to the different phosphine ligands on the4‐chloro‐2,6‐bis(1‐(p‐tolyl)‐1Htetrazol‐5‐yl)pyridine ruthenium(II)complexes,with that based on1,4‐bis(diphenylphosphino)butane exhibiting better catalytic activity.A variety of ketones were reduced to their corresponding alcohols with>95%conversion.展开更多
基金This work was supported by the NNSFC (No. 20372057) the NSF of Jiangsu Province (No. BK2001142)+2 种基金 the Open Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry and Chemical Engineering Suzhou University (No. S
文摘The title compound (C20H15ClN4O, Mr = 362.81) was synthesized by the reaction of ethyl 2-cyano-3-(2-chlorophenyl)-1-acylate with 5-amino-3-methyl-1-phenylpyrazole under microwave irradiation and its structure was determined by single-crystal X-ray diffraction. The crystal is of monoclinic, space group P21/n with a = 8.8192(19), b = 15.976(3), c = 13.094(3) ? = 103.074(4), V = 1797.1(7) ?, Z = 4, Dc = 1.341 g/cm3, = 0.229 mm-1, F(000) = 752, R = 0.0632 and wR = 0.1278. X-ray analysis reveals that the pyridine ring adopts an envelope conformation. The dihedral angle between the pyrazole and pyridine planes is 2.19, and inter- molecular hydrogen bonds are also observed in the molecule.
文摘Three ruthenium(II)complex catalysts bearing2,6‐bis(tetrazolyl)pyridine were synthesized,structurally characterized,and applied in the transfer hydrogenation of ketones.Their different catalytic activities were attributed to the different phosphine ligands on the4‐chloro‐2,6‐bis(1‐(p‐tolyl)‐1Htetrazol‐5‐yl)pyridine ruthenium(II)complexes,with that based on1,4‐bis(diphenylphosphino)butane exhibiting better catalytic activity.A variety of ketones were reduced to their corresponding alcohols with>95%conversion.
