AIM： TO investigate the agreement between esophageal manometry and pH step-up method in two different patient positions. METHODS： Eighteen subjects were included in the study. First, the distance from the nose to th...AIM： TO investigate the agreement between esophageal manometry and pH step-up method in two different patient positions. METHODS： Eighteen subjects were included in the study. First, the distance from the nose to the proximal border of the lower esophageal sphincter （LES） was measured manometrically. Then a different investigator, who was blinded to the results of the first study, measured the same distance using the pH step-up method, with the patient in both upright and supine positions. An assessment of agreement between the two techniques was performed. RESULTS： In the supine position, the measurement of only one subject was outside the range accepted for correct positioning （~〈 3 cm distal or proximal to the LES）. In the upright position, errors in measurement were recognized in five subjects. Bland-Airman plots revealed good agreement between measurements obtained manometrically and by the pH-step up method with the patient in the supine position. CONCLUSION： In the case of nonavailability of manometric detection device, the pH step-up method can facilitate the positioning of the 24 h pH monitoring catheter with the patient in the supine position. Thisshould increase the use of pH-metry in clinical practice for subjects with suspected gastroesophageal reflux disease if our results are supported by further studies.展开更多
The effect of yield-to-tensile strength ratio(Y/T) on failure pressure of X70 pipeline without and with corrosion defects was investigated.The stress-strain response of materials was characterized by a power-law harde...The effect of yield-to-tensile strength ratio(Y/T) on failure pressure of X70 pipeline without and with corrosion defects was investigated.The stress-strain response of materials was characterized by a power-law hardening curve.Two formulas to estimate the strain hardening exponent n for a special Y/T were obtained by least squared regression method and the influence of Y/T on n was analyzed.As an application of n-Y/T expression,the analytical solutions of burst pressure for X70 pipeline without and with corrosion defects were also obtained.The results indicate that the burst pressure of defect-free X70 pipe without corrosion defects is a function of the Y/T,pipe geometry t0/D0 and engineering tensile strength,and increases as Y/T or t0/D0 increases; whilst the burst pressure of corroded X70 pipe decreases with the increase of defect depths,d/t.Comparisons indicate that the present analytical solutions closely match available experimental and numerical data.展开更多
AIM: To determine the gastroesophageal refl uxate in the cervical esophagus (CE) and measure transcutaneous cervical esophageal ultrasound (TCEUS) f indings [anterior wall thickness (WT) of CE, esophageal luminal diam...AIM: To determine the gastroesophageal refl uxate in the cervical esophagus (CE) and measure transcutaneous cervical esophageal ultrasound (TCEUS) f indings [anterior wall thickness (WT) of CE, esophageal luminal diameter (ELD), esophageal diameter (ED)]; to compare TCEUS findings in the patient subgroups divided according to 24-h esophageal pH monitoring and manometry; and to investigate possible cut-off values according to the TCEUS f indings as a predictor of gastroesophageal refl ux (GER). METHODS: In 45/500 patients, refl uxate was visualized in TCEUS. 38/45 patients underwent esophagogastroduo denoscopy (EGD), 24-h pH monitoring and manometry. RESULTS: The 38 patients were grouped according to 24-h pH monitoring as follows: Group A: GER-positive (n = 20) [Includes Group B: isolated proximal refl ux (PR) (n = 6), Group C: isolated distal reflux (DR) (n = 6), and Group D: both PR/DR (n = 8)]; Group E: no refl ux (n = 13); and Group F: hypersensitive esophagus (HSE) (n = 5). Groups B + D indicated total PR patients (n = 14), Groups E + F refl ux-negatives with HSE (n = 18), and Groups A + F refl ux-positives with HSE (n = 25). When the 38 patients were grouped according to manometry fi ndings, 24 had normal esophageal manometry; 7 had hypotensive and 2 had hypertensive lower esophageal sphincter (LES); and 5 had ineffective esophageal motility disorder (IEM). The ELD measurement was greater in group A + F than group E (P = 0.023, 5.0 ± 1.3 vs 3.9 ± 1.4 mm). In 27/38 patients, there was at least one pathologic acid refl ux and/or pathologic manometry fi nding. The cut-off value for ELD of 4.83 mm had 79% sensitivity and 61% specificity in predicting the PRbetween Groups B + D and E (AUC = 0.775, P = 0.015). CONCLUSION: Visualizing refluxate in TCEUS was useful as a pre-diagnostic tool for estimating GER or manometric pathology in 71.1% of adults in our study, but it was not diagnostic for CE WT.展开更多
Coal mining with ploughs is an ideal coal mining technology for thin and thinner coal seams. The existence conditions of coal seams are different for each other, which affects coal mining with ploughs to different deg...Coal mining with ploughs is an ideal coal mining technology for thin and thinner coal seams. The existence conditions of coal seams are different for each other, which affects coal mining with ploughs to different degrees, and the application results are also different. The authors analyze the affecting factors by means of mathematical methods. The research is useful to the wide application of ploughs.展开更多
The most important objective of blasting in open pit mines is rock fragmentation.Prediction of produced boulders(oversized crushed rocks) is a key parameter in designing blast patterns.In this study,the amount of boul...The most important objective of blasting in open pit mines is rock fragmentation.Prediction of produced boulders(oversized crushed rocks) is a key parameter in designing blast patterns.In this study,the amount of boulder produced in blasting operations of Golegohar iron ore open pit mine,Iran was predicted via multiple regression method and artificial neural networks.Results of 33 blasts in the mine were collected for modeling.Input variables were:joints spacing,density and uniaxial compressive strength of the intact rock,burden,spacing,stemming,bench height to burden ratio,and specific charge.The dependent variable was ratio of boulder volume to pattern volume.Both techniques were successful in predicting the ratio.In this study,the multiple regression method was superior with coefficient of determination and root mean squared error values of 0.89 and 0.19,respectively.展开更多
The difficulties associated with performing direct compression strength tests on rocks lead to the development of indirect test methods for the rock strength assessment. Indirect test methods are simple, more economic...The difficulties associated with performing direct compression strength tests on rocks lead to the development of indirect test methods for the rock strength assessment. Indirect test methods are simple, more economical, less time-consuming, and easily adaptable to the field. The main aim of this study was to derive correlations between direct and indirect test methods for basalt and rhyolite rock types from Carlin trend deposits in Nevada. In the destructive methods, point load index, block punch index, and splitting tensile strength tests are performed. In the non-destructive methods, Schmidt hammer and ultrasonic pulse velocity tests are performed. Correlations between the direct and indirect compression strength tests are developed using linear and nonlinear regression analysis methods. The results show that the splitting tensile strength has the best correlation with the uniaxial compression strength.Furthermore, the Poisson's ratio has no correlation with any of the direct and indirect test results.展开更多
Recovery of heat energy from internal combustion engine exhaust will achieve significant road transportation CO2 reduction. Turbocharging and turbogenerating are most commonly used technologies to recover engine exhau...Recovery of heat energy from internal combustion engine exhaust will achieve significant road transportation CO2 reduction. Turbocharging and turbogenerating are most commonly used technologies to recover engine exhaust heat energy.Engine exhaust pulse flow can significantly affect the turbine performance of turbocharging and turbogenerating systems,and it is necessary to consider the pulse flow effects in turbine design and performance analysis.An investigation was carried out by numerical simulation on the mixed flow turbine pulse flow performance and flow fields.Results showed that the variations of the turbine efficiency and flowfiled under pulsating flow conditions demonstrate significant unsteady effects.The effect of blade leading edge sweep on turbine pulse flow performance was studied.It is shown that increasing of the leading edge sweep angle can improve the turbine average instantaneous efficiency by about 2 percent under pulsating flow conditions.展开更多
文摘AIM： TO investigate the agreement between esophageal manometry and pH step-up method in two different patient positions. METHODS： Eighteen subjects were included in the study. First, the distance from the nose to the proximal border of the lower esophageal sphincter （LES） was measured manometrically. Then a different investigator, who was blinded to the results of the first study, measured the same distance using the pH step-up method, with the patient in both upright and supine positions. An assessment of agreement between the two techniques was performed. RESULTS： In the supine position, the measurement of only one subject was outside the range accepted for correct positioning （~〈 3 cm distal or proximal to the LES）. In the upright position, errors in measurement were recognized in five subjects. Bland-Airman plots revealed good agreement between measurements obtained manometrically and by the pH-step up method with the patient in the supine position. CONCLUSION： In the case of nonavailability of manometric detection device, the pH step-up method can facilitate the positioning of the 24 h pH monitoring catheter with the patient in the supine position. Thisshould increase the use of pH-metry in clinical practice for subjects with suspected gastroesophageal reflux disease if our results are supported by further studies.
基金Project(N110607002)supported by the Fundamental Research Funds for the Central Universities of ChinaProject(51074052)supported by the National Natural Science Foundation of China
文摘The effect of yield-to-tensile strength ratio(Y/T) on failure pressure of X70 pipeline without and with corrosion defects was investigated.The stress-strain response of materials was characterized by a power-law hardening curve.Two formulas to estimate the strain hardening exponent n for a special Y/T were obtained by least squared regression method and the influence of Y/T on n was analyzed.As an application of n-Y/T expression,the analytical solutions of burst pressure for X70 pipeline without and with corrosion defects were also obtained.The results indicate that the burst pressure of defect-free X70 pipe without corrosion defects is a function of the Y/T,pipe geometry t0/D0 and engineering tensile strength,and increases as Y/T or t0/D0 increases; whilst the burst pressure of corroded X70 pipe decreases with the increase of defect depths,d/t.Comparisons indicate that the present analytical solutions closely match available experimental and numerical data.
文摘AIM: To determine the gastroesophageal refl uxate in the cervical esophagus (CE) and measure transcutaneous cervical esophageal ultrasound (TCEUS) f indings [anterior wall thickness (WT) of CE, esophageal luminal diameter (ELD), esophageal diameter (ED)]; to compare TCEUS findings in the patient subgroups divided according to 24-h esophageal pH monitoring and manometry; and to investigate possible cut-off values according to the TCEUS f indings as a predictor of gastroesophageal refl ux (GER). METHODS: In 45/500 patients, refl uxate was visualized in TCEUS. 38/45 patients underwent esophagogastroduo denoscopy (EGD), 24-h pH monitoring and manometry. RESULTS: The 38 patients were grouped according to 24-h pH monitoring as follows: Group A: GER-positive (n = 20) [Includes Group B: isolated proximal refl ux (PR) (n = 6), Group C: isolated distal reflux (DR) (n = 6), and Group D: both PR/DR (n = 8)]; Group E: no refl ux (n = 13); and Group F: hypersensitive esophagus (HSE) (n = 5). Groups B + D indicated total PR patients (n = 14), Groups E + F refl ux-negatives with HSE (n = 18), and Groups A + F refl ux-positives with HSE (n = 25). When the 38 patients were grouped according to manometry fi ndings, 24 had normal esophageal manometry; 7 had hypotensive and 2 had hypertensive lower esophageal sphincter (LES); and 5 had ineffective esophageal motility disorder (IEM). The ELD measurement was greater in group A + F than group E (P = 0.023, 5.0 ± 1.3 vs 3.9 ± 1.4 mm). In 27/38 patients, there was at least one pathologic acid refl ux and/or pathologic manometry fi nding. The cut-off value for ELD of 4.83 mm had 79% sensitivity and 61% specificity in predicting the PRbetween Groups B + D and E (AUC = 0.775, P = 0.015). CONCLUSION: Visualizing refluxate in TCEUS was useful as a pre-diagnostic tool for estimating GER or manometric pathology in 71.1% of adults in our study, but it was not diagnostic for CE WT.
文摘Coal mining with ploughs is an ideal coal mining technology for thin and thinner coal seams. The existence conditions of coal seams are different for each other, which affects coal mining with ploughs to different degrees, and the application results are also different. The authors analyze the affecting factors by means of mathematical methods. The research is useful to the wide application of ploughs.
文摘The most important objective of blasting in open pit mines is rock fragmentation.Prediction of produced boulders(oversized crushed rocks) is a key parameter in designing blast patterns.In this study,the amount of boulder produced in blasting operations of Golegohar iron ore open pit mine,Iran was predicted via multiple regression method and artificial neural networks.Results of 33 blasts in the mine were collected for modeling.Input variables were:joints spacing,density and uniaxial compressive strength of the intact rock,burden,spacing,stemming,bench height to burden ratio,and specific charge.The dependent variable was ratio of boulder volume to pattern volume.Both techniques were successful in predicting the ratio.In this study,the multiple regression method was superior with coefficient of determination and root mean squared error values of 0.89 and 0.19,respectively.
基金CDC/NIOSH for their partial funding of this work
文摘The difficulties associated with performing direct compression strength tests on rocks lead to the development of indirect test methods for the rock strength assessment. Indirect test methods are simple, more economical, less time-consuming, and easily adaptable to the field. The main aim of this study was to derive correlations between direct and indirect test methods for basalt and rhyolite rock types from Carlin trend deposits in Nevada. In the destructive methods, point load index, block punch index, and splitting tensile strength tests are performed. In the non-destructive methods, Schmidt hammer and ultrasonic pulse velocity tests are performed. Correlations between the direct and indirect compression strength tests are developed using linear and nonlinear regression analysis methods. The results show that the splitting tensile strength has the best correlation with the uniaxial compression strength.Furthermore, the Poisson's ratio has no correlation with any of the direct and indirect test results.
基金supported by the National Basic Research Program of China("973"Program)(Grant No.2011CB707204)the National Natural Science Foundation of China(Grant No.50706020)
文摘Recovery of heat energy from internal combustion engine exhaust will achieve significant road transportation CO2 reduction. Turbocharging and turbogenerating are most commonly used technologies to recover engine exhaust heat energy.Engine exhaust pulse flow can significantly affect the turbine performance of turbocharging and turbogenerating systems,and it is necessary to consider the pulse flow effects in turbine design and performance analysis.An investigation was carried out by numerical simulation on the mixed flow turbine pulse flow performance and flow fields.Results showed that the variations of the turbine efficiency and flowfiled under pulsating flow conditions demonstrate significant unsteady effects.The effect of blade leading edge sweep on turbine pulse flow performance was studied.It is shown that increasing of the leading edge sweep angle can improve the turbine average instantaneous efficiency by about 2 percent under pulsating flow conditions.
