AIM: To determine hepatitis C virus (HCV) seropreva- lence and its genotypes, and to identify the factors associated with HCV infection. METHODS: This cross-sectional study, conducted in two prisons (one male and...AIM: To determine hepatitis C virus (HCV) seropreva- lence and its genotypes, and to identify the factors associated with HCV infection. METHODS: This cross-sectional study, conducted in two prisons (one male and one female) in the State of Ser- gipe, Brazil, comprised 422 subjects. All of the prisoners underwent a rapid test for the detection of HCV antibod- ies. Patient~ with a positive result were tested for anti- HCV by enzyme linked immunosorbent assay and for HCV RNA by qualitative polymerase chain reaction (PCR). The virus genotype was defined in every serum sample that presented positive for PCR-HCV. In order to determine the factors independently associated with positive serol- ogy for HCV, multivariate logistic regression was used. RESULTS: HCV seroprevalence was 3.1%. Of the 13 subjects with positive anti-HCV, 11 had viremia confirmed by PCR. Of these, 90.9% had genotype 1. A total of 43 (10.2%) were injecting drug users, and HCV seroprevalence in this subgroup was 20.6%. The variable most strongly associated with positive serology for HCV was use of injecting drugs [odds ratio (OR), 23.3; 95% confidence interval (CI), 6.0-90.8]. Age over 30 years (OR, 5.5; 95%CI, 1.1-29.2), history of syphilis (OR, 9.8; 95%CI, 1.7-55.2) and history of household contact with HCV positive individual (OR, 14.1; 95%CI, 2.3-85.4) were also independently associated with HCV infection. CONCLUSION: Most of the HCV transmissions result from parenteral exposure. However, there is evidence to suggest a role for sex and household contact with an infected subject in virus transmission.展开更多
In this work, different flotation–preoxidation–cyanidation methods are considered for treating a lowgrade refractory gold ore. On the one hand, the results of selective flotation show that 22% and 31.1%of total Sb a...In this work, different flotation–preoxidation–cyanidation methods are considered for treating a lowgrade refractory gold ore. On the one hand, the results of selective flotation show that 22% and 31.1%of total Sb and As, respectively, remained in the final tailings and only about 28% of the total Au remained for further cyanidation processes. On the other hand, in bulk method of flotation the maximum Au recovery of 90.6% achieved after 60 min of flotation at the grind size with K80 of 146 micron. In addition, the bulk flotation method resulted in the concentrate with low concentrations of Sb and As elements. To improve the recovery of low-grade refractory gold ores, flotation should be followed by roasting, biological, or pressure oxidation processes so that the gold could be liberated prior to cyanidation processes. It is also found that the pressure oxidation pre-treatment of the concentrates prior to cyanidation may yield high gold recoveries of over than 83%. In these processes, recoveries are controlled by the temperature and the oxygen partial pressure in the solvent. However, by utilizing the bio-oxidation technique, the oxidation of sulfur to sulfate cannot be completed and, consequently, the gold recovery may be limited to only 72.2%.展开更多
The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marita...The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marital fertility are mostly negative particularly in developing countries. In Namibia, although premarital childbearing has been reported to be high and increasing, no studies have explicitly analyzed factors influencing non-marital fertility. This paper uses data from the 2006/7 Namibia DHS to establish the determinants of non-marital fertility among women by applying a two-part model, with one part to describe the presence of non-marital birth and the other part to explain its intensity (number of children born). Using the number of children ever born as an outcome, we explored various count data models. Based on the Voung statistics model comparison, we settled for the Hurdle logit Negative Binomial regression to model the number of non-marital births. Non-marital fertility in Namibia is associated with the age, with young women likely to have lower fertility compared to older women. Women with secondary or higher education had lower fertility compared those with no formal education. Findings also show that rural women higher fertility propensity compared to their urban counterparts even though there was no significant difference in fertility intensity. With regard to socio-economic status, fertility intensity decreased as the women got richer. Intervention efforts should focus on promoting education among girls and women especially in rural areas to improve their socio-economic status, reduce teenage pregnancy and non-marital fertility.展开更多
Objective:The aim of our study was to clarify the clinicopathological factors affecting the outcome of T1G3 urothelial carcinoma of the bladder.Methods:We retrospectively reviewed 62 cases of T1G3 bladder cancer treat...Objective:The aim of our study was to clarify the clinicopathological factors affecting the outcome of T1G3 urothelial carcinoma of the bladder.Methods:We retrospectively reviewed 62 cases of T1G3 bladder cancer treated with transuretheral resection of bladder toumor (TURBT) followed by intravesical instillation between 1997 and 2009.Cumulative survival was analyzed by Kaplan-Meier method.Cox regression was used for univariate and multivariate analysis.Log-rank method was used for the significance test.The statistical difference was accepted when the P value was lower than 0.05.Results:Median follow-up period was 40 months (6-140 months).Forty-one cases of intravesical recurrence (66%) were observed during follow-up.Two-and 5-year recurrence-free survival rates were 43.4% and 35.1%.Fourteen cases of progression (23%) were observed during the follow-up period.Two-and 5-year progression-free survival rates were 86.4% and 83.5%,respectively.Significant factors for tumor recurrence and progression were analyzed by Cox regression.Tumor multiplicity (RR=2.250),size (RR=1.039) and history of recurrence (RR=2.162) were significantly correlated with recurrence and tumor multiplicity (RR=3.695) was significantly correlated with progression on multivariate analysis.Conclusion:Tumor multiplicity,size,history of recurrence were correlated with recurrence and tumor multiplicity was significantly correlated with progression.Tumor multiplicity,size and history of recurrence should be taken into account when we make therapy strategies for T1G3 urothelial carcinoma of the bladder.展开更多
In this study, impact of inflation (WPI--Wholesale Price Index), exchange rate, and interest rate on the production of red meat in Turkey was examined using the vector autoregressive (VAR) model. The model consist...In this study, impact of inflation (WPI--Wholesale Price Index), exchange rate, and interest rate on the production of red meat in Turkey was examined using the vector autoregressive (VAR) model. The model consisting of variables of dollar exchange rate, inflation rate, interest rate, beef, buffalo meat, mutton, and goat meat production amounts has been estimated for the period from 1981 to 2014. It has been detected that there is a tie among the dollar exchange rate, inflation rate, interest rate, and the amount of red meat production in Turkey. In order to determine the direction of this relation, Granger causality test was conducted. A one-way causal relation has been observed between: the goat meat production and dollar exchange rate; the buffalo meat production and the mutton production; and the beef production and the mutton production. To interpret VAR model, the impulse response function and variance decomposition analysis was used. As a result of variance decomposition, it has been detected that explanatory power of changes in the variance of dollar exchange rate, inflation rate, and interest rate in goat meat production amount is more than explanatory power of changes in the variances of mutton, beef, and buffalo meat variables.展开更多
The identification of poverty at the county level is the precondition for poverty alleviation by formulating accurate strategies that are targeted for a certain area.Yunnan Province has the largest number of poverty c...The identification of poverty at the county level is the precondition for poverty alleviation by formulating accurate strategies that are targeted for a certain area.Yunnan Province has the largest number of poverty counties in China.The vast number of people living under the poverty-line,and the deep degree of poverty across a wide distribution range,pose major challenges.Based on the rural poverty incidence data,this paper describes the rural poverty patterns in Yunnan Province in 2010 and 2015,and then it explores the main factors which influence the incidence and changes in rural poverty at the county level in Yunnan Province using a stepwise regression analysis method.This study found that the rural poverty in counties of Yunnan Province was deeply affected by natural conditions and the geographical environment.In 2010 and 2015,the rural poverty situation in the middle region of Yunnan Province was relatively light,while it was more serious in the northwest,northeast and south regions.The pattern of county poverty is in good agreement with the topography and landforms of Yunnan Province and the poverty-stricken areas.There are strong correlations between the incidence of rural poverty in Yunnan Province with both the annual per capita net income of rural residents and the degree of agricultural mechanization.These factors are related to the living standards and agricultural production necessary for the peasantry to sustain their livelihood.The change in the incidence of rural poverty at the county level in Yunnan Province from 2010 to 2015 is significantly correlated with changes in the value-added of the primary industries and the degree of agricultural mechanization.These correlations indicate that the development of primary industry plays a key role in the process of lifting rural residents in Yunnan Province out of poverty so they can achieve prosperity.Therefore,improving the annual per capita net income of rural residents and the degree of agricultural mechanization for rural areas in Yunnan Province are still the main points for focused efforts.In the current phase of poverty alleviation,Yunnan Province should emphasize increasing rural residents'income and agricultural production and management in order to formulate effective policies and measures for poverty alleviation.展开更多
Background:Severe jejunoileal atresia is associated with prolonged parenteral nutrition,higher mortality and secondary surgery.However,the ideal surgical management of this condition remains controversial.This study a...Background:Severe jejunoileal atresia is associated with prolonged parenteral nutrition,higher mortality and secondary surgery.However,the ideal surgical management of this condition remains controversial.This study aimed to compare the outcomes of patients with severe jejunoileal atresia treated by three different procedures.Methods:From January 2007 to December 2016,105 neonates with severe jejunoileal atresia were retrospectively reviewed.Of these,42 patients(40.0%)underwent the Bishop–Koop procedure(BK group),49(46.7%)underwent primary anastomosis(PA group)and 14(13.3%)underwent Mikulicz double-barreled ileostomy(DB group).Demographics,treatment and outcomes including mortality,morbidity and nutrition status were reviewed and were compared among the three groups.Results:The total mortality rate was 6.7%,showing no statistical difference among the three groups(P=0.164).The BK group had the lowest post-operative complication rate(33.3%vs 65.3%for the PA group and 71.4%for the DB group,P=0.003)and re-operation rate(4.8%vs 38.8%for the PA group and 14.3%for the DB group,P<0.001).Compared with the BK group,the PA group showed a positive correlation with the complication rate and re-operation rate,with an odds ratio of 4.15[95%confidence interval(CI):1.57,10.96]and 12.78(95%CI:2.58,63.29),respectively.The DB group showed a positive correlation with the complication rate when compared with the BK group,with an odds ratio of 7.73(95%CI:1.67,35.72).The weight-for-age Z-score at stoma closure was–1.22(95%CI:–1.91,–0.54)in the BK group and–2.84(95%CI:–4.28,–1.40)in the DB group(P=0.039).Conclusions:The Bishop–Koop procedure for severe jejunoileal atresia had a low complication rate and re-operation rate,and the nutrition status at stoma closure was superior to double-barreled enterostomy.The Bishop–Koop procedure seems to be an appropriate choice for severe jejunoileal atresia.展开更多
Background and objective:The benefit from adjuvant chemotherapy for patients treated with neoadjuvant chemoradiotherapy(NCRT)and curative surgery remains controversial,particularly among those responding well to NCRT....Background and objective:The benefit from adjuvant chemotherapy for patients treated with neoadjuvant chemoradiotherapy(NCRT)and curative surgery remains controversial,particularly among those responding well to NCRT.This retrospective study aimed to clarify the benefits of adjuvant chemotherapy in terms of the oncological outcomes of patients with ypT0–2N0 rectal cancer after NCRT and curative surgery.Methods:All patients with ypT0–2N0 rectal cancer after NCRT and curative resection between 2005 and 2014 were examined.The oncological outcomes between patients treated with adjuvant chemotherapy and those without any chemotherapy were compared.Results:The clinicopathological characteristics of 110 patients were reviewed in this study;one patient was excluded due to lack of follow-up.Of the 109 patients included,58(53.2%)underwent adjuvant chemotherapy(chemo group),whereas the remaining 51(46.8%)did not receive any chemotherapy(non-chemo group).After a median follow-up of 50 months,there were no significant differences in the 5-year overall survival(OS)or recurrence-free survival(RFS)rates between the groups(OS:92.1 vs 86.3%,P=0.375;RFS:80.9 vs 74.7%,P=0.534).Subgroup analysis also demonstrated no significant differences in 5-year OS and RFS rates between patients with ypT0N0 rectal cancer(P=0.712 and P=0.599,respectively)and those with ypT1–2N0 disease(P=0.255 and P=0.278,respectively).Conclusions:These results indicate that patients with ypT0–2N0 rectal cancer after NCRT followed by curative surgery may not derive significant benefit from adjuvant chemotherapy.However,further prospective randomized trials,with larger sample sizes,are warranted to confirm this conclusion.展开更多
文摘AIM: To determine hepatitis C virus (HCV) seropreva- lence and its genotypes, and to identify the factors associated with HCV infection. METHODS: This cross-sectional study, conducted in two prisons (one male and one female) in the State of Ser- gipe, Brazil, comprised 422 subjects. All of the prisoners underwent a rapid test for the detection of HCV antibod- ies. Patient~ with a positive result were tested for anti- HCV by enzyme linked immunosorbent assay and for HCV RNA by qualitative polymerase chain reaction (PCR). The virus genotype was defined in every serum sample that presented positive for PCR-HCV. In order to determine the factors independently associated with positive serol- ogy for HCV, multivariate logistic regression was used. RESULTS: HCV seroprevalence was 3.1%. Of the 13 subjects with positive anti-HCV, 11 had viremia confirmed by PCR. Of these, 90.9% had genotype 1. A total of 43 (10.2%) were injecting drug users, and HCV seroprevalence in this subgroup was 20.6%. The variable most strongly associated with positive serology for HCV was use of injecting drugs [odds ratio (OR), 23.3; 95% confidence interval (CI), 6.0-90.8]. Age over 30 years (OR, 5.5; 95%CI, 1.1-29.2), history of syphilis (OR, 9.8; 95%CI, 1.7-55.2) and history of household contact with HCV positive individual (OR, 14.1; 95%CI, 2.3-85.4) were also independently associated with HCV infection. CONCLUSION: Most of the HCV transmissions result from parenteral exposure. However, there is evidence to suggest a role for sex and household contact with an infected subject in virus transmission.
文摘In this work, different flotation–preoxidation–cyanidation methods are considered for treating a lowgrade refractory gold ore. On the one hand, the results of selective flotation show that 22% and 31.1%of total Sb and As, respectively, remained in the final tailings and only about 28% of the total Au remained for further cyanidation processes. On the other hand, in bulk method of flotation the maximum Au recovery of 90.6% achieved after 60 min of flotation at the grind size with K80 of 146 micron. In addition, the bulk flotation method resulted in the concentrate with low concentrations of Sb and As elements. To improve the recovery of low-grade refractory gold ores, flotation should be followed by roasting, biological, or pressure oxidation processes so that the gold could be liberated prior to cyanidation processes. It is also found that the pressure oxidation pre-treatment of the concentrates prior to cyanidation may yield high gold recoveries of over than 83%. In these processes, recoveries are controlled by the temperature and the oxygen partial pressure in the solvent. However, by utilizing the bio-oxidation technique, the oxidation of sulfur to sulfate cannot be completed and, consequently, the gold recovery may be limited to only 72.2%.
文摘The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marital fertility are mostly negative particularly in developing countries. In Namibia, although premarital childbearing has been reported to be high and increasing, no studies have explicitly analyzed factors influencing non-marital fertility. This paper uses data from the 2006/7 Namibia DHS to establish the determinants of non-marital fertility among women by applying a two-part model, with one part to describe the presence of non-marital birth and the other part to explain its intensity (number of children born). Using the number of children ever born as an outcome, we explored various count data models. Based on the Voung statistics model comparison, we settled for the Hurdle logit Negative Binomial regression to model the number of non-marital births. Non-marital fertility in Namibia is associated with the age, with young women likely to have lower fertility compared to older women. Women with secondary or higher education had lower fertility compared those with no formal education. Findings also show that rural women higher fertility propensity compared to their urban counterparts even though there was no significant difference in fertility intensity. With regard to socio-economic status, fertility intensity decreased as the women got richer. Intervention efforts should focus on promoting education among girls and women especially in rural areas to improve their socio-economic status, reduce teenage pregnancy and non-marital fertility.
文摘Objective:The aim of our study was to clarify the clinicopathological factors affecting the outcome of T1G3 urothelial carcinoma of the bladder.Methods:We retrospectively reviewed 62 cases of T1G3 bladder cancer treated with transuretheral resection of bladder toumor (TURBT) followed by intravesical instillation between 1997 and 2009.Cumulative survival was analyzed by Kaplan-Meier method.Cox regression was used for univariate and multivariate analysis.Log-rank method was used for the significance test.The statistical difference was accepted when the P value was lower than 0.05.Results:Median follow-up period was 40 months (6-140 months).Forty-one cases of intravesical recurrence (66%) were observed during follow-up.Two-and 5-year recurrence-free survival rates were 43.4% and 35.1%.Fourteen cases of progression (23%) were observed during the follow-up period.Two-and 5-year progression-free survival rates were 86.4% and 83.5%,respectively.Significant factors for tumor recurrence and progression were analyzed by Cox regression.Tumor multiplicity (RR=2.250),size (RR=1.039) and history of recurrence (RR=2.162) were significantly correlated with recurrence and tumor multiplicity (RR=3.695) was significantly correlated with progression on multivariate analysis.Conclusion:Tumor multiplicity,size,history of recurrence were correlated with recurrence and tumor multiplicity was significantly correlated with progression.Tumor multiplicity,size and history of recurrence should be taken into account when we make therapy strategies for T1G3 urothelial carcinoma of the bladder.
文摘In this study, impact of inflation (WPI--Wholesale Price Index), exchange rate, and interest rate on the production of red meat in Turkey was examined using the vector autoregressive (VAR) model. The model consisting of variables of dollar exchange rate, inflation rate, interest rate, beef, buffalo meat, mutton, and goat meat production amounts has been estimated for the period from 1981 to 2014. It has been detected that there is a tie among the dollar exchange rate, inflation rate, interest rate, and the amount of red meat production in Turkey. In order to determine the direction of this relation, Granger causality test was conducted. A one-way causal relation has been observed between: the goat meat production and dollar exchange rate; the buffalo meat production and the mutton production; and the beef production and the mutton production. To interpret VAR model, the impulse response function and variance decomposition analysis was used. As a result of variance decomposition, it has been detected that explanatory power of changes in the variance of dollar exchange rate, inflation rate, and interest rate in goat meat production amount is more than explanatory power of changes in the variances of mutton, beef, and buffalo meat variables.
基金The Key Project of National Natural Science Foundation of China(41130748)。
文摘The identification of poverty at the county level is the precondition for poverty alleviation by formulating accurate strategies that are targeted for a certain area.Yunnan Province has the largest number of poverty counties in China.The vast number of people living under the poverty-line,and the deep degree of poverty across a wide distribution range,pose major challenges.Based on the rural poverty incidence data,this paper describes the rural poverty patterns in Yunnan Province in 2010 and 2015,and then it explores the main factors which influence the incidence and changes in rural poverty at the county level in Yunnan Province using a stepwise regression analysis method.This study found that the rural poverty in counties of Yunnan Province was deeply affected by natural conditions and the geographical environment.In 2010 and 2015,the rural poverty situation in the middle region of Yunnan Province was relatively light,while it was more serious in the northwest,northeast and south regions.The pattern of county poverty is in good agreement with the topography and landforms of Yunnan Province and the poverty-stricken areas.There are strong correlations between the incidence of rural poverty in Yunnan Province with both the annual per capita net income of rural residents and the degree of agricultural mechanization.These factors are related to the living standards and agricultural production necessary for the peasantry to sustain their livelihood.The change in the incidence of rural poverty at the county level in Yunnan Province from 2010 to 2015 is significantly correlated with changes in the value-added of the primary industries and the degree of agricultural mechanization.These correlations indicate that the development of primary industry plays a key role in the process of lifting rural residents in Yunnan Province out of poverty so they can achieve prosperity.Therefore,improving the annual per capita net income of rural residents and the degree of agricultural mechanization for rural areas in Yunnan Province are still the main points for focused efforts.In the current phase of poverty alleviation,Yunnan Province should emphasize increasing rural residents'income and agricultural production and management in order to formulate effective policies and measures for poverty alleviation.
基金supported by the Science and Technology Planning Project of Guangdong Province(2014A020212022).
文摘Background:Severe jejunoileal atresia is associated with prolonged parenteral nutrition,higher mortality and secondary surgery.However,the ideal surgical management of this condition remains controversial.This study aimed to compare the outcomes of patients with severe jejunoileal atresia treated by three different procedures.Methods:From January 2007 to December 2016,105 neonates with severe jejunoileal atresia were retrospectively reviewed.Of these,42 patients(40.0%)underwent the Bishop–Koop procedure(BK group),49(46.7%)underwent primary anastomosis(PA group)and 14(13.3%)underwent Mikulicz double-barreled ileostomy(DB group).Demographics,treatment and outcomes including mortality,morbidity and nutrition status were reviewed and were compared among the three groups.Results:The total mortality rate was 6.7%,showing no statistical difference among the three groups(P=0.164).The BK group had the lowest post-operative complication rate(33.3%vs 65.3%for the PA group and 71.4%for the DB group,P=0.003)and re-operation rate(4.8%vs 38.8%for the PA group and 14.3%for the DB group,P<0.001).Compared with the BK group,the PA group showed a positive correlation with the complication rate and re-operation rate,with an odds ratio of 4.15[95%confidence interval(CI):1.57,10.96]and 12.78(95%CI:2.58,63.29),respectively.The DB group showed a positive correlation with the complication rate when compared with the BK group,with an odds ratio of 7.73(95%CI:1.67,35.72).The weight-for-age Z-score at stoma closure was–1.22(95%CI:–1.91,–0.54)in the BK group and–2.84(95%CI:–4.28,–1.40)in the DB group(P=0.039).Conclusions:The Bishop–Koop procedure for severe jejunoileal atresia had a low complication rate and re-operation rate,and the nutrition status at stoma closure was superior to double-barreled enterostomy.The Bishop–Koop procedure seems to be an appropriate choice for severe jejunoileal atresia.
基金supported by National Key R&D Program of China(No.2017YFC0908203)and CAMS Initiative for Innovative Medicine(No.CAMS-I2M-003).
文摘Background and objective:The benefit from adjuvant chemotherapy for patients treated with neoadjuvant chemoradiotherapy(NCRT)and curative surgery remains controversial,particularly among those responding well to NCRT.This retrospective study aimed to clarify the benefits of adjuvant chemotherapy in terms of the oncological outcomes of patients with ypT0–2N0 rectal cancer after NCRT and curative surgery.Methods:All patients with ypT0–2N0 rectal cancer after NCRT and curative resection between 2005 and 2014 were examined.The oncological outcomes between patients treated with adjuvant chemotherapy and those without any chemotherapy were compared.Results:The clinicopathological characteristics of 110 patients were reviewed in this study;one patient was excluded due to lack of follow-up.Of the 109 patients included,58(53.2%)underwent adjuvant chemotherapy(chemo group),whereas the remaining 51(46.8%)did not receive any chemotherapy(non-chemo group).After a median follow-up of 50 months,there were no significant differences in the 5-year overall survival(OS)or recurrence-free survival(RFS)rates between the groups(OS:92.1 vs 86.3%,P=0.375;RFS:80.9 vs 74.7%,P=0.534).Subgroup analysis also demonstrated no significant differences in 5-year OS and RFS rates between patients with ypT0N0 rectal cancer(P=0.712 and P=0.599,respectively)and those with ypT1–2N0 disease(P=0.255 and P=0.278,respectively).Conclusions:These results indicate that patients with ypT0–2N0 rectal cancer after NCRT followed by curative surgery may not derive significant benefit from adjuvant chemotherapy.However,further prospective randomized trials,with larger sample sizes,are warranted to confirm this conclusion.