The Fe, Zn, Mn and Pb concentrations in the seawater dissolved phase were investigated in the sea-surface microlayer (SML), subsurface water (SSW) and bottom water (BW) samples collected at of three mariculture ...The Fe, Zn, Mn and Pb concentrations in the seawater dissolved phase were investigated in the sea-surface microlayer (SML), subsurface water (SSW) and bottom water (BW) samples collected at of three mariculture areas of the Nanao Island ocean zone. The results showed that the SML and the BW were important compartments for these heavy metals in the mariculture areas and the concentrations varied from 23.0 μg/L to 268.0 μg/L(Fe), 11.0 μg/L to 82.2 μg/L(Zn), 1.5 μg/L to 11.0 μg/L(Mn) and 6.0 μg/L to 40.5 μg/L(Pb) in SSW, while a clear enrichment is observed in the SML, where these ranged from 27.5 μg/L to 286.5 μg/L(Fe), 13.5/lg/L to 89.0μg/L(Zn), 3.0μg/L to 12.0 μg/L(Mn) and 7.0 μg/L to 46.0μg/L(Pb). The enrichment factors were in the range of 1.07 - 1.39 which showed a slight enrichment. The average enrichment factors of Fe, Zn, Pb and Mn were 1.18, 1.13, 1.12 and 1.30, respectively. The average enrichment factors in shellfish, fish and gracilaria lemaneaformis farming areas were 1.26, 1.19 and 1.11, respectively, which showed that the surface activity was highest in the shellfish farming area. Furthermore, the heavy metals concentrations were lowest in the gracUaria lemaneaformis farming area. The results of single factor contamination index showed that the investigated areas were slightly contaminated with Zn, while the partial farming areas were seriously contaminated with Pd during a certain period of time.展开更多
The veracity of land evaluation is tightly related to the reasonable weights of land evaluation fac- tors. By mapping qualitative linguistic words into a fine-changeable cloud drops and translating the uncertain facto...The veracity of land evaluation is tightly related to the reasonable weights of land evaluation fac- tors. By mapping qualitative linguistic words into a fine-changeable cloud drops and translating the uncertain factor conditions into quantitative values with the uncertain illation based on cloud model, and then, inte- grating correlation analysis, a new way of figuring out the weight of land evaluation factors is proposed. It may solve the limitations of the conventional ways.展开更多
This paper presents an procedure for purifying training data sets (i.e., past occurrences of slope failures) for inverse estimation on unobserved trigger factors of "different types of simultaneous slope failures"...This paper presents an procedure for purifying training data sets (i.e., past occurrences of slope failures) for inverse estimation on unobserved trigger factors of "different types of simultaneous slope failures". Due to difficulties in pixel-by-pixel observations of trigger factors, as one of the measures, the authors had proposed an inverse analysis algorithm on trigger factors based on SEM (structural equation modeling). Through a measurement equation, the trigger factor is inversely estimated, and a TFI (trigger factor influence) map can be also produced. As a subsequence subject, a purification procedure of training data set should be constructed to improve the accuracy of TFI map which depends on the representativeness of given training data sets of different types of slope failures. The proposed procedure resamples the matched pixels between original groups of past slope failures (i.e., surface slope failures, deep-seated slope failures, landslides) and classified three groups by K-means clustering for all pixels corresponding to those slope failures. For all cases of three types of slope failures, the improvement of success rates with respect to resampled training data sets was confirmed. As a final outcome, the differences between TFI maps produced by using original and resampled training data sets, respectively, are delineated on a DIF map (difference map) which is useful for analyzing trigger factor influence in terms of "risky- and safe-side assessment" sub-areas with respect to "different types of simultaneous slope failures".展开更多
AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-...AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were enrolled.Analyzed parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital stay.RESULTS:The weekday and weekend admission groups comprised 326 and 62 patients,respectively.There were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend group.Most patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend admission.CONCLUSION:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.展开更多
The background of the study is based on previous studies dealing with the areas of Transdanubia of Hungary. Those works have proved the hypothesis of author that local ingredients and dishes represent minimum role on ...The background of the study is based on previous studies dealing with the areas of Transdanubia of Hungary. Those works have proved the hypothesis of author that local ingredients and dishes represent minimum role on menus. The question is how similar or different the choice of menus of Budapest-Middle-Danube compared with the previously examined areas of Hungary. There can be another question about the usage of local ingredients available near to the catering units. This piece of work has studied 79 menus of Budapest-Middle-Danube, Hungary. The material was collected from different types of restaurants, small restaurants (vendeglo in Hungarian) and roadside restaurants (csarda in Hungarian). The method of the work was on the one hand, data collecting, and on the other hand, examination of the differences between the catering units in details: the number of dishes, the right order of dishes, the appearance of local ingredients and dishes, the consideration of seasonality, the usage of different cooking methods and group of dishes. The study reflects the main problems of countryside restaurants in Hungary. Only minimum number of dishes could be connected to local dishes out of more than thousands. All in all, dishes are not as precise and perfect as the "old ones", so that is why it is important for every expert keep the traditions alive in daily routines and strategic mean too.展开更多
The problem of scattering of SH-wave by a circular cavity and an arbitrary beeline crack in right-angle plane was investigated using the methods of Green's function,complex variables and muti-polar coordinates.Fir...The problem of scattering of SH-wave by a circular cavity and an arbitrary beeline crack in right-angle plane was investigated using the methods of Green's function,complex variables and muti-polar coordinates.Firstly,we constructed a suitable Green's function,which is an essential solution to the displacement field for the elastic right-angle plane possessing a circular cavity while bearing out-of-plane harmonic line source load at arbitrary point.Secondly,based on the method of crack-division,integration for solution was established,then expressions of displacement and stress were obtained while crack and circular cavities were both in existence.Finally,the dynamic stress concentration factor around the circular cavity and the dynamic stress intensity factor at crack tip were discussed to the cases of different parameters in numerical examples.Calculation results show that the crack produces adverse engineering influence on both of the dynamic stress concentration factor and the dynamic stress intensity factor.展开更多
The timing of river entry in the Atlantic salmon is known to depend on genetic, demographic and environmental factors, but little is known about the relative magnitude of among population and among year variation and ...The timing of river entry in the Atlantic salmon is known to depend on genetic, demographic and environmental factors, but little is known about the relative magnitude of among population and among year variation and covariation in this respect in natural state Atlantic salmon rives. To investigate this, variability in the timing of river entry in three historical Finnish Atlantic salmon populations were analyzed using salmon trap data collected during 1870- 1902. The analyses reveled that 1 ) the timing of river entry differed substantially and consistently among the rivers, and that 2) variation among the rivers was much larger than variation among years. Annual variations were not explained by regional environmental conditions, whereas in one river the timing of the local flood peak was a significant predictor of the timing of river entry. Differences in the timing of salmon entry to geographically closely situated rivers suggests that a regionally fixed opening date for coastal fisheries might not be the best management strategy as it may lead to uneven exploitation of salmon populations from different rivers [ Current Zoology 55 (5) : 342 - 349, 2009] .展开更多
In order to improve the practical approach to clinical diagnosis of subclinical mastitis, 72 dairy cattle from KPSBU Lembang Bandung Regency was used in this research. The purpose of this research was to study the cor...In order to improve the practical approach to clinical diagnosis of subclinical mastitis, 72 dairy cattle from KPSBU Lembang Bandung Regency was used in this research. The purpose of this research was to study the correlation between udder length and lactation period with the profile of subclinical mastitis. Lactation period data was collected from interviews with farmers. Subclinical mastitis testing by IPB-1 Mastitis Test reagent and udder length measured using measuring tape (cm). Data was analyzed using Duncan test and logistic regression. The highest correlation of subclinical mastitis occurred to dairy cattle with average udder length of 7.5 cm and was in the third and forth lactation period. This result shows that udder length and lactation period of dairy cattle is a predisposing factor for subclinical mastitis. This finding is important to improve the milking management as well as a way to diagnose subclinical mastitis.展开更多
This study aims at investigating the AIS (Agricultural Information System) in Hamedan province, Iran, benefiting from the list of criteria for well functioning AISs that were identified in earlier researches. For th...This study aims at investigating the AIS (Agricultural Information System) in Hamedan province, Iran, benefiting from the list of criteria for well functioning AISs that were identified in earlier researches. For this purpose, a survey method with multi-stage stratified random sampling technique was used to select 31 agricultural researchers, and 62 extension workers in the province. The data were acquired by questionnaire and structured interviews. The instrument for data collection was subjected to pre-testing, validation and reliability tests. The results of the factor analysis revealed that the criteria could be categorized into four overarching groups based on their inter-correlation. The analysis of mentioned criteria in Hamedan province AIS showed less efficiency and effectiveness than studies conducted in other areas. But among these, two desirable criteria existed. It is recommended that the ecological knowledge system (EKS) should be integrated with AIS, and some ecological and sustainable development criteria should be added to the existing ones.展开更多
Microarray and deep sequencing technologies have provided unprecedented opportunities for mapping genome mutations,RNA transcripts,transcription factor binding,and histone modifications at high resolution at the genom...Microarray and deep sequencing technologies have provided unprecedented opportunities for mapping genome mutations,RNA transcripts,transcription factor binding,and histone modifications at high resolution at the genome-wide level.This has revolutionized the way in which transcriptomes,regulatory networks and epigenetic regulations have been studied and large amounts of heterogeneous data have been generated.Although efforts are being made to integrate these datasets unbiasedly and efficiently,how best to do this still remains a challenge.Here we review major impacts of high-throughput genome-wide data generation,their relevance to human diseases,and various bioinformatics approaches for data integration.Finally,we provide a case study on inflammatory diseases.展开更多
A multisymplectic Fourier pseudo-spectral scheme, which exactly preserves the discrete multisym- plectic conservation law, is presented to solve the Klein-Gordon-SchrSdinger equations. The scheme is of spectral accura...A multisymplectic Fourier pseudo-spectral scheme, which exactly preserves the discrete multisym- plectic conservation law, is presented to solve the Klein-Gordon-SchrSdinger equations. The scheme is of spectral accuracy in space and of second order in time. The scheme preserves the discrete multisymplectic conservation law and the charge conservation law. Moreover, the residuals of some other conservation laws are derived for the geometric numerical integrator. Extensive numerical simulations illustrate the numerical behavior of the multisymplectic scheme, and demonstrate the correctness of the theoretical analysis.展开更多
RNA-Seq promises to be used in clinical settings as a gene-expression profiling tool;however,questions about its variability and biases remain and need to be addressed.Thus,RNA controls with known concentrations and s...RNA-Seq promises to be used in clinical settings as a gene-expression profiling tool;however,questions about its variability and biases remain and need to be addressed.Thus,RNA controls with known concentrations and sequence identities originally developed by the External RNA Control Consortium(ERCC) for microarray and qPCR platforms have recently been proposed for RNA-Seq platforms,but only with a limited number of samples.In this study,we report our analysis of RNA-Seq data from 92 ERCC controls spiked in a diverse collection of 447 RNA samples from eight ongoing studies involving five species(human,rat,mouse,chicken,and Schistosoma japonicum) and two mRNA enrichment protocols,i.e.,poly(A) and RiboZero.The entire collection of datasets consisted of 15650143175 short sequence reads,131603796(i.e.,0.84%) of which were mapped to the 92 ERCC references.The overall ERCC mapping ratio of 0.84% is close to the expected value of 1.0% when assuming a 2.0% mRNA fraction in total RNA,but showed a difference of 2.8-fold across studies and 4.3-fold among samples from the same study with one tissue type.This level of fluctuation may prevent the ERCC controls from being used for cross-sample normalization in RNA-Seq.Furthermore,we observed striking biases of quantification between poly(A) and RiboZero which are transcript-specific.For example,ERCC-00116 showed a 7.3-fold under-enrichment in poly(A) compared to RiboZero.Extra care is needed in integrative analysis of multiple datasets and technical artifacts of protocol differences should not be taken as true biological findings.展开更多
基金supported by the National Natural Science Foundation of China (No.40673062)
文摘The Fe, Zn, Mn and Pb concentrations in the seawater dissolved phase were investigated in the sea-surface microlayer (SML), subsurface water (SSW) and bottom water (BW) samples collected at of three mariculture areas of the Nanao Island ocean zone. The results showed that the SML and the BW were important compartments for these heavy metals in the mariculture areas and the concentrations varied from 23.0 μg/L to 268.0 μg/L(Fe), 11.0 μg/L to 82.2 μg/L(Zn), 1.5 μg/L to 11.0 μg/L(Mn) and 6.0 μg/L to 40.5 μg/L(Pb) in SSW, while a clear enrichment is observed in the SML, where these ranged from 27.5 μg/L to 286.5 μg/L(Fe), 13.5/lg/L to 89.0μg/L(Zn), 3.0μg/L to 12.0 μg/L(Mn) and 7.0 μg/L to 46.0μg/L(Pb). The enrichment factors were in the range of 1.07 - 1.39 which showed a slight enrichment. The average enrichment factors of Fe, Zn, Pb and Mn were 1.18, 1.13, 1.12 and 1.30, respectively. The average enrichment factors in shellfish, fish and gracilaria lemaneaformis farming areas were 1.26, 1.19 and 1.11, respectively, which showed that the surface activity was highest in the shellfish farming area. Furthermore, the heavy metals concentrations were lowest in the gracUaria lemaneaformis farming area. The results of single factor contamination index showed that the investigated areas were slightly contaminated with Zn, while the partial farming areas were seriously contaminated with Pd during a certain period of time.
文摘The veracity of land evaluation is tightly related to the reasonable weights of land evaluation fac- tors. By mapping qualitative linguistic words into a fine-changeable cloud drops and translating the uncertain factor conditions into quantitative values with the uncertain illation based on cloud model, and then, inte- grating correlation analysis, a new way of figuring out the weight of land evaluation factors is proposed. It may solve the limitations of the conventional ways.
文摘This paper presents an procedure for purifying training data sets (i.e., past occurrences of slope failures) for inverse estimation on unobserved trigger factors of "different types of simultaneous slope failures". Due to difficulties in pixel-by-pixel observations of trigger factors, as one of the measures, the authors had proposed an inverse analysis algorithm on trigger factors based on SEM (structural equation modeling). Through a measurement equation, the trigger factor is inversely estimated, and a TFI (trigger factor influence) map can be also produced. As a subsequence subject, a purification procedure of training data set should be constructed to improve the accuracy of TFI map which depends on the representativeness of given training data sets of different types of slope failures. The proposed procedure resamples the matched pixels between original groups of past slope failures (i.e., surface slope failures, deep-seated slope failures, landslides) and classified three groups by K-means clustering for all pixels corresponding to those slope failures. For all cases of three types of slope failures, the improvement of success rates with respect to resampled training data sets was confirmed. As a final outcome, the differences between TFI maps produced by using original and resampled training data sets, respectively, are delineated on a DIF map (difference map) which is useful for analyzing trigger factor influence in terms of "risky- and safe-side assessment" sub-areas with respect to "different types of simultaneous slope failures".
文摘AIM:To evaluate whether weekend or nighttime admission affects prognosis of peptic ulcer bleeding despite early endoscopy.METHODS:Retrospective data collection from four referral centers,all of which had a formal out-of-hours emergency endoscopy service,even at weekends.A total of 388 patients with bleeding peptic ulcers who were admitted via the emergency room between January 2007 and December 2009 were enrolled.Analyzed parameters included time from patients' arrival until endoscopy,mortality,rebleeding,need for surgery and length of hospital stay.RESULTS:The weekday and weekend admission groups comprised 326 and 62 patients,respectively.There were no significant differences in baseline characteristics between the two groups,except for younger age in the weekend group.Most patients (97%) had undergone early endoscopy,which resulted in a low mortality rate regardless of point of presentation (1.8% overall vs 1.6% on the weekend).The only outcome that was worse in the weekend group was a higher rate of rebleeding (12% vs 21%,P = 0.030).However,multivariate analysis revealed nighttime admission and a high Rockall score (≥ 6) as significant independent risk factors for rebleeding,rather than weekend admission.CONCLUSION:Early endoscopy for peptic ulcer bleeding can prevent the weekend effect,and nighttime admission was identified as a novel risk factor for rebleeding,namely the nighttime effect.
文摘The background of the study is based on previous studies dealing with the areas of Transdanubia of Hungary. Those works have proved the hypothesis of author that local ingredients and dishes represent minimum role on menus. The question is how similar or different the choice of menus of Budapest-Middle-Danube compared with the previously examined areas of Hungary. There can be another question about the usage of local ingredients available near to the catering units. This piece of work has studied 79 menus of Budapest-Middle-Danube, Hungary. The material was collected from different types of restaurants, small restaurants (vendeglo in Hungarian) and roadside restaurants (csarda in Hungarian). The method of the work was on the one hand, data collecting, and on the other hand, examination of the differences between the catering units in details: the number of dishes, the right order of dishes, the appearance of local ingredients and dishes, the consideration of seasonality, the usage of different cooking methods and group of dishes. The study reflects the main problems of countryside restaurants in Hungary. Only minimum number of dishes could be connected to local dishes out of more than thousands. All in all, dishes are not as precise and perfect as the "old ones", so that is why it is important for every expert keep the traditions alive in daily routines and strategic mean too.
文摘The problem of scattering of SH-wave by a circular cavity and an arbitrary beeline crack in right-angle plane was investigated using the methods of Green's function,complex variables and muti-polar coordinates.Firstly,we constructed a suitable Green's function,which is an essential solution to the displacement field for the elastic right-angle plane possessing a circular cavity while bearing out-of-plane harmonic line source load at arbitrary point.Secondly,based on the method of crack-division,integration for solution was established,then expressions of displacement and stress were obtained while crack and circular cavities were both in existence.Finally,the dynamic stress concentration factor around the circular cavity and the dynamic stress intensity factor at crack tip were discussed to the cases of different parameters in numerical examples.Calculation results show that the crack produces adverse engineering influence on both of the dynamic stress concentration factor and the dynamic stress intensity factor.
基金supported by Academy of Finland and the University of Helsinki
文摘The timing of river entry in the Atlantic salmon is known to depend on genetic, demographic and environmental factors, but little is known about the relative magnitude of among population and among year variation and covariation in this respect in natural state Atlantic salmon rives. To investigate this, variability in the timing of river entry in three historical Finnish Atlantic salmon populations were analyzed using salmon trap data collected during 1870- 1902. The analyses reveled that 1 ) the timing of river entry differed substantially and consistently among the rivers, and that 2) variation among the rivers was much larger than variation among years. Annual variations were not explained by regional environmental conditions, whereas in one river the timing of the local flood peak was a significant predictor of the timing of river entry. Differences in the timing of salmon entry to geographically closely situated rivers suggests that a regionally fixed opening date for coastal fisheries might not be the best management strategy as it may lead to uneven exploitation of salmon populations from different rivers [ Current Zoology 55 (5) : 342 - 349, 2009] .
文摘In order to improve the practical approach to clinical diagnosis of subclinical mastitis, 72 dairy cattle from KPSBU Lembang Bandung Regency was used in this research. The purpose of this research was to study the correlation between udder length and lactation period with the profile of subclinical mastitis. Lactation period data was collected from interviews with farmers. Subclinical mastitis testing by IPB-1 Mastitis Test reagent and udder length measured using measuring tape (cm). Data was analyzed using Duncan test and logistic regression. The highest correlation of subclinical mastitis occurred to dairy cattle with average udder length of 7.5 cm and was in the third and forth lactation period. This result shows that udder length and lactation period of dairy cattle is a predisposing factor for subclinical mastitis. This finding is important to improve the milking management as well as a way to diagnose subclinical mastitis.
文摘This study aims at investigating the AIS (Agricultural Information System) in Hamedan province, Iran, benefiting from the list of criteria for well functioning AISs that were identified in earlier researches. For this purpose, a survey method with multi-stage stratified random sampling technique was used to select 31 agricultural researchers, and 62 extension workers in the province. The data were acquired by questionnaire and structured interviews. The instrument for data collection was subjected to pre-testing, validation and reliability tests. The results of the factor analysis revealed that the criteria could be categorized into four overarching groups based on their inter-correlation. The analysis of mentioned criteria in Hamedan province AIS showed less efficiency and effectiveness than studies conducted in other areas. But among these, two desirable criteria existed. It is recommended that the ecological knowledge system (EKS) should be integrated with AIS, and some ecological and sustainable development criteria should be added to the existing ones.
文摘Microarray and deep sequencing technologies have provided unprecedented opportunities for mapping genome mutations,RNA transcripts,transcription factor binding,and histone modifications at high resolution at the genome-wide level.This has revolutionized the way in which transcriptomes,regulatory networks and epigenetic regulations have been studied and large amounts of heterogeneous data have been generated.Although efforts are being made to integrate these datasets unbiasedly and efficiently,how best to do this still remains a challenge.Here we review major impacts of high-throughput genome-wide data generation,their relevance to human diseases,and various bioinformatics approaches for data integration.Finally,we provide a case study on inflammatory diseases.
基金supported by National Natural Science Foundation of China(Grant Nos.10901074,11271171,91130003,11001009 and 11101399)the Province Natural Science Foundation of Jiangxi(Grant No. 20114BAB201011)+2 种基金the Foundation of Department of Education of Jiangxi Province(Grant No.GJJ12174)the State Key Laboratory of Scientific and Engineering Computing,CASsupported by the Youth Growing Foundation of Jiangxi Normal University in 2010
文摘A multisymplectic Fourier pseudo-spectral scheme, which exactly preserves the discrete multisym- plectic conservation law, is presented to solve the Klein-Gordon-SchrSdinger equations. The scheme is of spectral accuracy in space and of second order in time. The scheme preserves the discrete multisymplectic conservation law and the charge conservation law. Moreover, the residuals of some other conservation laws are derived for the geometric numerical integrator. Extensive numerical simulations illustrate the numerical behavior of the multisymplectic scheme, and demonstrate the correctness of the theoretical analysis.
文摘RNA-Seq promises to be used in clinical settings as a gene-expression profiling tool;however,questions about its variability and biases remain and need to be addressed.Thus,RNA controls with known concentrations and sequence identities originally developed by the External RNA Control Consortium(ERCC) for microarray and qPCR platforms have recently been proposed for RNA-Seq platforms,but only with a limited number of samples.In this study,we report our analysis of RNA-Seq data from 92 ERCC controls spiked in a diverse collection of 447 RNA samples from eight ongoing studies involving five species(human,rat,mouse,chicken,and Schistosoma japonicum) and two mRNA enrichment protocols,i.e.,poly(A) and RiboZero.The entire collection of datasets consisted of 15650143175 short sequence reads,131603796(i.e.,0.84%) of which were mapped to the 92 ERCC references.The overall ERCC mapping ratio of 0.84% is close to the expected value of 1.0% when assuming a 2.0% mRNA fraction in total RNA,but showed a difference of 2.8-fold across studies and 4.3-fold among samples from the same study with one tissue type.This level of fluctuation may prevent the ERCC controls from being used for cross-sample normalization in RNA-Seq.Furthermore,we observed striking biases of quantification between poly(A) and RiboZero which are transcript-specific.For example,ERCC-00116 showed a 7.3-fold under-enrichment in poly(A) compared to RiboZero.Extra care is needed in integrative analysis of multiple datasets and technical artifacts of protocol differences should not be taken as true biological findings.