围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性...围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性自杀率,减少不良妊娠结局的关键。中医药治疗PND疗效确切且优势明显,能克服西医治疗的不良反应和毒副作用,具有良好的应用前景。本文通过疏理文献对PND发生的危险因素及中医药治疗进展做一综述,以期为预防PND的发生及临床治疗提供科学依据。Perinatal depression (PND) is a prevalent mental disorder among women during the perinatal period, significantly impacting the physical and mental health of both women and their offspring. The onset of PND is associated with a variety of factors including women’s physiology, psychology, economics, and societal influences, but the pathogenesis remains incompletely understood. Early diagnosis, intervention and treatment are crucial in preventing the worsening of depression, reducing the suicide rate among perinatal women, and mitigating adverse pregnancy outcomes. Traditional Chinese medicine (TCM) has exhibited definitive efficacy and advantages in treating PND, which overcomes the adverse reactions and toxic effects of Western medicine and presents promising application prospects. This article presents a comprehensive review of the risk factors for PND and the advancements in TCM treatment, to provide a scientific basis for the prevention and clinical treatment of PND.展开更多
文摘围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性自杀率,减少不良妊娠结局的关键。中医药治疗PND疗效确切且优势明显,能克服西医治疗的不良反应和毒副作用,具有良好的应用前景。本文通过疏理文献对PND发生的危险因素及中医药治疗进展做一综述,以期为预防PND的发生及临床治疗提供科学依据。Perinatal depression (PND) is a prevalent mental disorder among women during the perinatal period, significantly impacting the physical and mental health of both women and their offspring. The onset of PND is associated with a variety of factors including women’s physiology, psychology, economics, and societal influences, but the pathogenesis remains incompletely understood. Early diagnosis, intervention and treatment are crucial in preventing the worsening of depression, reducing the suicide rate among perinatal women, and mitigating adverse pregnancy outcomes. Traditional Chinese medicine (TCM) has exhibited definitive efficacy and advantages in treating PND, which overcomes the adverse reactions and toxic effects of Western medicine and presents promising application prospects. This article presents a comprehensive review of the risk factors for PND and the advancements in TCM treatment, to provide a scientific basis for the prevention and clinical treatment of PND.
