This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has bee...This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has been made by Chinese in nearly every branches of tissue culture, including in vitro organogenesis, shoot tip culture, anther culture, ovary culture, endosperm culture, protoplast culture as well as mass cell culture. On the basis of reviewing the articles written by Chinese on plant tissue culture, the internationally recognized contributions are specially mentioned. The applications of plant tissue culture to agriculture and industry in China are also introduced.展开更多
The work of Chinese scientists conducted at the Joint Institute for Nuclear Research(JINR)(1956–1965)was inextricably linked to the Sino-Soviet relations in the 1950 s–1960 s.During the early stage of the JINR,with ...The work of Chinese scientists conducted at the Joint Institute for Nuclear Research(JINR)(1956–1965)was inextricably linked to the Sino-Soviet relations in the 1950 s–1960 s.During the early stage of the JINR,with the aid of advanced equipment and the international cooperation mechanism,Chinese scientists yielded significant results,such as the discovery of the antisigma-minus hyperon and the proof of the law of partial conservation of axial current(PCAC).After the Sino-Soviet split,Chinese scientists’activities at the institute were hampered by political tensions,eventually resulting in China’s withdrawal from the JINR in 1965.But through the involvement at the JINR,Chinese scientists were trained in scientific practices and participated in international exchange and cooperation which turned them into a new force in China’s nuclear industry,boosting its nuclear weapons,particle physics theory,and accelerator technology.In the meantime,the scientists’activities extended the international influence of the JINR.The withdrawal of China from the institute impacted both the JINR and the development of science in China.展开更多
To use a national database of United States hospitals to evaluate the incidence and costs of hospital admissions associated with gastroparesis. METHODSWe analyzed the National Inpatient Sample Database (NIS) for all p...To use a national database of United States hospitals to evaluate the incidence and costs of hospital admissions associated with gastroparesis. METHODSWe analyzed the National Inpatient Sample Database (NIS) for all patients in whom gastroparesis (ICD-9 code: 536.3) was the principal discharge diagnosis during the period, 1997-2013. The NIS is the largest publicly available all-payer inpatient care database in the United States. It contains data from approximately eight million hospital stays each year. The statistical significance of the difference in the number of hospital discharges, length of stay and hospital costs over the study period was determined by regression analysis. RESULTSIn 1997, there were 3978 admissions with a principal discharge diagnosis of gastroparesis as compared to 16460 in 2013 (P < 0.01). The mean length of stay for gastroparesis decreased by 20 % between 1997 and 2013 from 6.4 d to 5.1 d (P < 0.001). However, during this period the mean hospital charges increased significantly by 159 % from $13350 (after inflation adjustment) per patient in 1997 to $34585 per patient in 2013 (P < 0.001). The aggregate charges (i.e., “national bill”) for gastroparesis increased exponentially by 1026 % from $50456642 ± 4662620 in 1997 to $568417666 ± 22374060 in 2013 (P < 0.001). The percentage of national bill for gastroparesis discharges (national bill for gastroparesis/total national bill) has also increased over the last 16 years (0.0013% in 1997 vs 0.004% in 2013). During the study period, women had a higher frequency of gastroparesis discharges when compared to men (1.39/10000 vs 0.9/10000 in 1997 and 5.8/10000 vs 3/10000 in 2013). There was a 6-fold increase in the discharge diagnosis of gastroparesis amongst type 1 DM and 3.7-fold increase amongst type 2 DM patients over the study period (P < 0.001). CONCLUSIONThe number of inpatient admissions for gastroparesis and associated costs have increased significantly over the last 16 years. Inpatient costs associated with gastroparesis contribute significantly to the national healthcare bill. Further research on cost-effective evaluation and management of gastroparesis is required.展开更多
Negative skin friction (NSF) is one of the important problems when designing a pile foundation. However, the influence of loading sequence on the dragload and downdrag for pile foundation is seldom studied. In this pa...Negative skin friction (NSF) is one of the important problems when designing a pile foundation. However, the influence of loading sequence on the dragload and downdrag for pile foundation is seldom studied. In this paper, a three-dimensional numerical model was established using FLAC3D. Compared with the results of model test, the established model could be used to study the NSF of pile foundation. The influencing factors were discussed including the length-diameter ratio of pile and the loading sequence of pile head load and surcharge. A case history was analyzed using FLAC3D. The calculated results are in good agreement with the measured results. It is concluded that the dragload and downdrag are remarkably influenced by the loading sequence of pile head load and surcharge. The dragload and downdrag reach the maximum values under the condition of surcharge after pile head load.展开更多
The transmission of science and technology from the Soviet Union to People’s Republic of China in the mid-twentieth century is an important research area of contemporary history of science and technology.This paper t...The transmission of science and technology from the Soviet Union to People’s Republic of China in the mid-twentieth century is an important research area of contemporary history of science and technology.This paper takes the construction of the cyclotron in Lanzhou,China as the case to discuss the characteristics of technology transfer from the Soviet Union to China.The review of extensive archives reveals that the construction of cyclotron took place in the framework of China’s nuclear weapons development.Although the transmission of science and technology from the Soviet Union to China fit into the one-way transmission-reception model in general,both the Chinese demand and the Soviet response had key influences on the transmission.In the early cyclotron construction,the Chinese side relied on the Soviets,and the mode of the cooperation between Soviet and Chinese engineers can be described as one of expertstudent.In the early 1960 s,the relationship between China and the Soviet Union broke down.The Soviet engineers were required to withdraw with the technical data,which created conflicts in the roles played by the Soviet engineers,most of whom chose to set the sense of professional responsibility as their highest priority.After the departure of the Soviet experts,Chinese physicists played the leading role in the project,using scientific knowledge they had,relying on the technical materials left by Soviet experts,and cooperating fully with local engineers,thus completing the cyclotron.This case can provide us with valuable clues for the understanding of transnational history of science and technology.The seemingly one-way transmission-reception model is actually influenced by the needs of both sides.While the transnational flow of knowledge is inevitably affected by political factors from both sides,the process is far more complex than it appears.展开更多
Climate engineering is a potential alternative method to curb global warming, and this discipline has garnered considerable attention from the intemational scientific community including the Chinese scientists. This m...Climate engineering is a potential alternative method to curb global warming, and this discipline has garnered considerable attention from the intemational scientific community including the Chinese scientists. This manuscript provides an overview of several aspects of climate engi- neering, including its definition, its potential impacts and risk, and its governance status. The overall conclusion is that China is not yet ready to implement climate engineering. However, it is important for China to continue conducting research on climate engineering, particularly with respect to its feasible application within China, its potential social, economic, and environmental impacts, and possible international governance structures and governing principles, with regard to both experimentatio~ and implementation.展开更多
Presently the gold standard diagnostic technique for rabies is the direct immunofluorescence assay （dFA） which is very expensive and requires a high level of expertise. There is a need for more economical and user f...Presently the gold standard diagnostic technique for rabies is the direct immunofluorescence assay （dFA） which is very expensive and requires a high level of expertise. There is a need for more economical and user friendly tests, particularly for use in developing countries. We have established one such test called the direct rapid immunohistochemical test （dRIT） for diagnosis of rabies using brain tissue. The test is based on capture of rabies nucleoprotein （N） antigen in brain smears using a cocktail of biotinylated monoclonal antibodies specific for the N protein and color development by streptavidin peroxidase-amino ethyl carbazole and counter staining with haematoxollin. The test was done in parallel with standard FAT dFA using 400 brain samples from different animals and humans. The rabies virus N protein appears under fight microscope as reddish brown particles against a light blue background. There was 100 % correlation between the results obtained by the two tests. Also, interpretation of results by dRIT was easier and only required a light microscope. To conclude, this newly developed dRIT technique promises to be a simple, cost effective diagnostic tool for rabies and will have applicability in field conditions prevalent in developing countries.展开更多
文摘This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has been made by Chinese in nearly every branches of tissue culture, including in vitro organogenesis, shoot tip culture, anther culture, ovary culture, endosperm culture, protoplast culture as well as mass cell culture. On the basis of reviewing the articles written by Chinese on plant tissue culture, the internationally recognized contributions are specially mentioned. The applications of plant tissue culture to agriculture and industry in China are also introduced.
基金supported in part by the Youth Innovation Promotion Association CAS(2018186)the National Science Foundation of China(NSFC)under Grant No.11775207。
文摘The work of Chinese scientists conducted at the Joint Institute for Nuclear Research(JINR)(1956–1965)was inextricably linked to the Sino-Soviet relations in the 1950 s–1960 s.During the early stage of the JINR,with the aid of advanced equipment and the international cooperation mechanism,Chinese scientists yielded significant results,such as the discovery of the antisigma-minus hyperon and the proof of the law of partial conservation of axial current(PCAC).After the Sino-Soviet split,Chinese scientists’activities at the institute were hampered by political tensions,eventually resulting in China’s withdrawal from the JINR in 1965.But through the involvement at the JINR,Chinese scientists were trained in scientific practices and participated in international exchange and cooperation which turned them into a new force in China’s nuclear industry,boosting its nuclear weapons,particle physics theory,and accelerator technology.In the meantime,the scientists’activities extended the international influence of the JINR.The withdrawal of China from the institute impacted both the JINR and the development of science in China.
文摘To use a national database of United States hospitals to evaluate the incidence and costs of hospital admissions associated with gastroparesis. METHODSWe analyzed the National Inpatient Sample Database (NIS) for all patients in whom gastroparesis (ICD-9 code: 536.3) was the principal discharge diagnosis during the period, 1997-2013. The NIS is the largest publicly available all-payer inpatient care database in the United States. It contains data from approximately eight million hospital stays each year. The statistical significance of the difference in the number of hospital discharges, length of stay and hospital costs over the study period was determined by regression analysis. RESULTSIn 1997, there were 3978 admissions with a principal discharge diagnosis of gastroparesis as compared to 16460 in 2013 (P < 0.01). The mean length of stay for gastroparesis decreased by 20 % between 1997 and 2013 from 6.4 d to 5.1 d (P < 0.001). However, during this period the mean hospital charges increased significantly by 159 % from $13350 (after inflation adjustment) per patient in 1997 to $34585 per patient in 2013 (P < 0.001). The aggregate charges (i.e., “national bill”) for gastroparesis increased exponentially by 1026 % from $50456642 ± 4662620 in 1997 to $568417666 ± 22374060 in 2013 (P < 0.001). The percentage of national bill for gastroparesis discharges (national bill for gastroparesis/total national bill) has also increased over the last 16 years (0.0013% in 1997 vs 0.004% in 2013). During the study period, women had a higher frequency of gastroparesis discharges when compared to men (1.39/10000 vs 0.9/10000 in 1997 and 5.8/10000 vs 3/10000 in 2013). There was a 6-fold increase in the discharge diagnosis of gastroparesis amongst type 1 DM and 3.7-fold increase amongst type 2 DM patients over the study period (P < 0.001). CONCLUSIONThe number of inpatient admissions for gastroparesis and associated costs have increased significantly over the last 16 years. Inpatient costs associated with gastroparesis contribute significantly to the national healthcare bill. Further research on cost-effective evaluation and management of gastroparesis is required.
基金Supported by National Natural Science Foundation of China (No.50679015)China Postdoctoral Science Foundation (No.20090461062)
文摘Negative skin friction (NSF) is one of the important problems when designing a pile foundation. However, the influence of loading sequence on the dragload and downdrag for pile foundation is seldom studied. In this paper, a three-dimensional numerical model was established using FLAC3D. Compared with the results of model test, the established model could be used to study the NSF of pile foundation. The influencing factors were discussed including the length-diameter ratio of pile and the loading sequence of pile head load and surcharge. A case history was analyzed using FLAC3D. The calculated results are in good agreement with the measured results. It is concluded that the dragload and downdrag are remarkably influenced by the loading sequence of pile head load and surcharge. The dragload and downdrag reach the maximum values under the condition of surcharge after pile head load.
基金supported by one of the projects of the National 14th Five-Year Plan:“Compilation of the Volume on History of Science and Technology of the New General History of China”(《(新编)中国通史》科学技术史卷)。
文摘The transmission of science and technology from the Soviet Union to People’s Republic of China in the mid-twentieth century is an important research area of contemporary history of science and technology.This paper takes the construction of the cyclotron in Lanzhou,China as the case to discuss the characteristics of technology transfer from the Soviet Union to China.The review of extensive archives reveals that the construction of cyclotron took place in the framework of China’s nuclear weapons development.Although the transmission of science and technology from the Soviet Union to China fit into the one-way transmission-reception model in general,both the Chinese demand and the Soviet response had key influences on the transmission.In the early cyclotron construction,the Chinese side relied on the Soviets,and the mode of the cooperation between Soviet and Chinese engineers can be described as one of expertstudent.In the early 1960 s,the relationship between China and the Soviet Union broke down.The Soviet engineers were required to withdraw with the technical data,which created conflicts in the roles played by the Soviet engineers,most of whom chose to set the sense of professional responsibility as their highest priority.After the departure of the Soviet experts,Chinese physicists played the leading role in the project,using scientific knowledge they had,relying on the technical materials left by Soviet experts,and cooperating fully with local engineers,thus completing the cyclotron.This case can provide us with valuable clues for the understanding of transnational history of science and technology.The seemingly one-way transmission-reception model is actually influenced by the needs of both sides.While the transnational flow of knowledge is inevitably affected by political factors from both sides,the process is far more complex than it appears.
基金supported by the National Basic Research Program of China (2015CB953603)
文摘Climate engineering is a potential alternative method to curb global warming, and this discipline has garnered considerable attention from the intemational scientific community including the Chinese scientists. This manuscript provides an overview of several aspects of climate engi- neering, including its definition, its potential impacts and risk, and its governance status. The overall conclusion is that China is not yet ready to implement climate engineering. However, it is important for China to continue conducting research on climate engineering, particularly with respect to its feasible application within China, its potential social, economic, and environmental impacts, and possible international governance structures and governing principles, with regard to both experimentatio~ and implementation.
文摘Presently the gold standard diagnostic technique for rabies is the direct immunofluorescence assay （dFA） which is very expensive and requires a high level of expertise. There is a need for more economical and user friendly tests, particularly for use in developing countries. We have established one such test called the direct rapid immunohistochemical test （dRIT） for diagnosis of rabies using brain tissue. The test is based on capture of rabies nucleoprotein （N） antigen in brain smears using a cocktail of biotinylated monoclonal antibodies specific for the N protein and color development by streptavidin peroxidase-amino ethyl carbazole and counter staining with haematoxollin. The test was done in parallel with standard FAT dFA using 400 brain samples from different animals and humans. The rabies virus N protein appears under fight microscope as reddish brown particles against a light blue background. There was 100 % correlation between the results obtained by the two tests. Also, interpretation of results by dRIT was easier and only required a light microscope. To conclude, this newly developed dRIT technique promises to be a simple, cost effective diagnostic tool for rabies and will have applicability in field conditions prevalent in developing countries.
