The impact of learning on brain functional laterality has not been systematically investigated. We em- ployed an event-related functional magnetic resonance im- aging combined with a delayed sequential movement task t...The impact of learning on brain functional laterality has not been systematically investigated. We em- ployed an event-related functional magnetic resonance im- aging combined with a delayed sequential movement task to investigate brain activation pattern and laterality during a transient practice in 12 subjects. Both hemispheres, involving motor areas and posterior parietal cortex, were engaged during motor preparation and execution, with larger activa- tion volume in the left hemisphere than in the right. Activa- tion volume in these regions significantly decreased after a transient practice, with more reduction in the right hemi- sphere resulting increase in left lateralization. The theoretical implications of these findings are discussed in relation to the physiological significance of brain functional laterality.展开更多
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.30425008,30128005,and 30170325)the National Basic Research Program of China(Grant No.G1999054000)the Health Bureau of Zhejiang Province(Grant No.2002B019).
文摘The impact of learning on brain functional laterality has not been systematically investigated. We em- ployed an event-related functional magnetic resonance im- aging combined with a delayed sequential movement task to investigate brain activation pattern and laterality during a transient practice in 12 subjects. Both hemispheres, involving motor areas and posterior parietal cortex, were engaged during motor preparation and execution, with larger activa- tion volume in the left hemisphere than in the right. Activa- tion volume in these regions significantly decreased after a transient practice, with more reduction in the right hemi- sphere resulting increase in left lateralization. The theoretical implications of these findings are discussed in relation to the physiological significance of brain functional laterality.
