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纵向均匀静磁场中无限长导电圆柱体的磁弹性问题
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作者 徐耀玲 白象忠 《齐齐哈尔大学学报(自然科学版)》 1999年第3期23-26,共4页
以磁弹性耦合场理论为基础,分析了处于纵向均匀静磁场中且表面承受周期性负载的无限长导电圆柱体,建立了可解方程,并给出了径向位移和自由空间中磁场挑动的解析解。
关键词 磁弹 圆柱性 电磁场 纵向均匀静磁场
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家族性圆柱瘤基因在病理性瘢痕中的表达 被引量:1
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作者 唐小清 贺光照 俞泽浩 《重庆医科大学学报》 CAS CSCD 北大核心 2015年第1期147-150,共4页
目的:探讨家族性圆柱瘤基因(cylindromatosis,CYLD)在病理性瘢痕组织及成纤维细胞中的表达及意义。方法:收集临床手术切除的皮肤标本72例,分为正常皮肤组(20例)、正常瘢痕组(14例)、瘢痕疙瘩组(25例)、增生性瘢痕组(13例)。免疫组织化... 目的:探讨家族性圆柱瘤基因(cylindromatosis,CYLD)在病理性瘢痕组织及成纤维细胞中的表达及意义。方法:收集临床手术切除的皮肤标本72例,分为正常皮肤组(20例)、正常瘢痕组(14例)、瘢痕疙瘩组(25例)、增生性瘢痕组(13例)。免疫组织化学技术(SP法)和Western blot检测各组织中CYLD蛋白的表达情况并对结果进行差异比较;另收集瘢痕疙瘩、增生性瘢痕及周围正常皮肤组织各10例,采用组织块贴壁法进行原代成纤维细胞培养,Western blot测定CYLD蛋白在3种成纤维细胞中的表达情况。结果:1免疫组化结果表明CYLD蛋白在A组(0.762±0.039)与B组(0.721±0.042)中的阳性表达明显高于C组(0.173±0.069)与D组(0.213±0.072),(F=213.832,P=0.000);C组、D组分别与A组比较(P值均为0.000),C组、D组分别与B组比较差异均具有统计学意义(P值均为0.000);2Western blot结果显示CYLD蛋白在正常皮肤(0.550±0.030)与正常瘢痕组织(0.442±0.016)中的表达明显高于瘢痕疙瘩(0.068±0.013)与增生性瘢痕(0.178±0.009)(F=424.685,P=0.000);3CYLD蛋白在正常成纤维细胞(0.564±0.037)中的表达同样明显高于瘢痕疙瘩(0.240±0.022)与增生性瘢痕成纤维细胞(0.256±0.038)(F=90.306,P=0.000)。结论:CYLD蛋白在病理性瘢痕成纤维中的表达低于正常皮肤与正常瘢痕,说明CYLD的低表达可能与病理性瘢痕的形成具有一定的关系。 展开更多
关键词 病理瘢痕 家族圆柱瘤基因 成纤维细胞
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CYLD基因在Brooke-Spiegler综合征、家族性圆柱瘤和多发性家族性毛发上皮瘤中的基因突变:缺乏基因型-显型关联性 被引量:3
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作者 Bowen S. Gill M. +2 位作者 Lee D.A. J.T. Celebi 阎小宁 《世界核心医学期刊文摘(皮肤病学分册)》 2005年第9期20-21,共2页
Brooke-Spiegler syndrome (BSS), familial cylindromatosis (FC), and multiple familial trichoepithelioma (MFT), originally described as distinct entities, share overlapping clinical findings. Patients with BSS are predi... Brooke-Spiegler syndrome (BSS), familial cylindromatosis (FC), and multiple familial trichoepithelioma (MFT), originally described as distinct entities, share overlapping clinical findings. Patients with BSS are predisposed to multiple skin appendage tumors such as cylindroma, trichoepithelioma, and spiradenoma. FC, however, is characterized by cylindromas and MFT by trichoepitheliomas as the only tumor type. These disorders have recently been associated with mutations in the CYLD gene. In this report, we describe three families with BSS, one with FC, and two with MFT phenotypes associated with novel and recurrent mutations in CYLD. We provide evidence that these disorders represent phenotypic variation of a single entity and lack genotype-phenotype correlation. 展开更多
关键词 家族圆柱 CYLD基因 毛发上皮瘤 基因突变 汗腺腺瘤 显型 单个个体
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大倾角劲性斜圆柱施工精度控制关键技术
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作者 胡勋波 杨慕尧 +2 位作者 刘传雨 梁月文 韩敏章 《建筑技术》 2023年第S01期48-49,共2页
安徽百戏城项目共有大倾角劲性斜圆柱16根,倾角、方向与高差各不相同。若斜圆柱施工过程中倾角及方向稍有偏差便会引起误差的产生,导致斜圆柱与梁板接头有较大的错位,如何保障斜圆柱的精度成为工程急需解决的问题。项目利用BIM放样技术... 安徽百戏城项目共有大倾角劲性斜圆柱16根,倾角、方向与高差各不相同。若斜圆柱施工过程中倾角及方向稍有偏差便会引起误差的产生,导致斜圆柱与梁板接头有较大的错位,如何保障斜圆柱的精度成为工程急需解决的问题。项目利用BIM放样技术,精确斜圆柱在每层梁板交界处的坐标;利用模型转化,将斜圆柱受力模型转化为混凝土梁模型,简化其受力形式,实现了普通支撑体系的支模方法。利用三维扫描技术进行全过程扫描,以保障施工精度。 展开更多
关键词 大倾角 圆柱 BIM 三维扫描
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劲性圆柱梁柱节点模板新型加固施工技术
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作者 何欣 谢磊 程勋明 《中文科技期刊数据库(全文版)工程技术》 2021年第11期289-292,共4页
型钢混凝土结构在目前的高层和超高层建筑中被广泛采用,针对该结构施工中遇到的模板加固难题,尤其是劲性圆柱的梁、柱接头处模板支设较为困难。针对圆形柱部位模板支设,研制了蝴蝶卡扣成套装置并应用,效果良好,对确保型钢混凝土施工达... 型钢混凝土结构在目前的高层和超高层建筑中被广泛采用,针对该结构施工中遇到的模板加固难题,尤其是劲性圆柱的梁、柱接头处模板支设较为困难。针对圆形柱部位模板支设,研制了蝴蝶卡扣成套装置并应用,效果良好,对确保型钢混凝土施工达到工期进度要求和确保施工质量具有良好的指导意义。 展开更多
关键词 圆柱 梁柱节点 蝴蝶卡扣 加固
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轻型家族性圆柱瘤病与CYLD肿瘤抑制基因的一个R758X无义突变有关
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作者 Oiso N. Mizuno N. +1 位作者 Fukai K. 冯义国 《世界核心医学期刊文摘(皮肤病学分册)》 2005年第4期14-14,共1页
Familial cylindromatosis is a rare dominantly inherited disease characterized by the development of multiple benign tumours of the skin appendages, including cylindromas, trichoepitheliomas and spiradenomas. The gene ... Familial cylindromatosis is a rare dominantly inherited disease characterized by the development of multiple benign tumours of the skin appendages, including cylindromas, trichoepitheliomas and spiradenomas. The gene responsible was positionally cloned recently, and was designated CYLD.We describe a family with cylindromatosis, in which affected individuals have an inherited R758X nonsense mutation of CYLD. Affected members of this family manifest a relativelymild tumour phenotype; the largest tumour was only 30 mm in diameter. Thus far, there is no evident genotype-phenotype relationship in cylindromatosis, although the number of families reported with both phenotypic and genotypic data remains small. 展开更多
关键词 家族圆柱 CYLD R758X 无义突变 肿瘤抑制基因 毛发上皮瘤 皮肤附属器肿瘤 圆柱瘤病 表现型 遗传
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Compressive properties of glue-laminated timber circular post modified by basalt fiber reinforced polymer
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作者 WEI Peixing GUO Wenzhen +2 位作者 ZHAO Mingjing GUO Zhensheng WANG Jianhe 《林业工程学报》 CSCD 北大核心 2024年第5期67-74,共8页
Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-... Glued timber structure is one of the main forms of modern wood architecture,which has gradually developed towards mid-and high-rise buildings.Glue-laminated timber(GLT)is comprised of several laminates of parallel-to-grain dimension lumber that are bonded together with durable,moisture resistant structural adhesives.GLT can be used in horizontal applications as a beam and in vertical applications as a post.So,its compressive performance has a significant impact on structural safety.Fiber reinforced polymers(FRPs)were commonly used to improve the bearing capacity of GLT components,and the structural and process parameters largely determined the reinforcement effect.This study was aimed at investigating the influence of structural and process parameters on the axial compression performance of GLT components.Three wrapping methods(middle-part,end-part and full wrapping)and three lengths(0.6,0.8,and 1.0 m)of wood post specimens were designed in this work and the axial compression performance and ductility of GLT post specimens modified by basalt fiber reinforced polymer(BFRP)were studied.The results showed that the effect of different BFRP wrapping methods on the compressive strength and elastic modulus of laminated wood was not statistically significant(P>0.05).The compressive bearing capacity of unreinforced GLT posts decreased with the increase of aspect ratio.The GLT posts with middle-part and end-part wrapping still followed this pattern,while the compressive bearing capacity of GLT posts with full wrapping showed a pattern of first decreasing and then increasing.For GLT with low aspect ratios(4.0 or 5.3),there was no correlation between the wrapping method and the compressive bearing capacity,while the compressive bearing capacity of GLT with a high aspect ratio(6.7)for middle-part,end-part and full wrapping increased by 3.5%,7.5%and 9.7%,respectively.Compared to the unreinforced group,the ultimate axial compressive strength and modulus of elasticity(MOE)of the 6-E series specimens reinforced at both ends decreased by 2.58%and 6.70%,respectively.The ultimate axial compressive strength of the 8-E specimens reinforced at both ends increased by 8.62%and the MOE decreased by 1.91%.The compressive strength of the 10-E specimens reinforced at both ends increased by 7.51%and the MOE increased by 8.14%.The failure modes of GLT with different aspects were consistent under the same BFRP wrapping,while the failure modes of GLT with the same aspect ratio were different for different BFRP wrapping methods.The ductility performance of GLT with different aspects ratio was improved by the BFRP wrapping. 展开更多
关键词 basalt fiber reinforced polymer(BFRP) GLT circular post bearing performance
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CYLD1基因与皮肤附属器肿瘤 被引量:2
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作者 杨梅 梁燕华 +1 位作者 杨森 张学军 《中国麻风皮肤病杂志》 2008年第6期458-460,共3页
CYLD1基因是一种肿瘤抑制基因,在经典的NF-κB信号转导途径中发挥重要的生物学作用,影响炎症、免疫反应及肿瘤的形成,参与多种皮肤病的发生发展,如色素失禁症、少汗性外胚层发育不良等。本文仅就CYLD1基因异常与皮肤附属器肿瘤(多发性... CYLD1基因是一种肿瘤抑制基因,在经典的NF-κB信号转导途径中发挥重要的生物学作用,影响炎症、免疫反应及肿瘤的形成,参与多种皮肤病的发生发展,如色素失禁症、少汗性外胚层发育不良等。本文仅就CYLD1基因异常与皮肤附属器肿瘤(多发性家族性毛发上皮瘤、家族性圆柱瘤、Brook-Spiegler综合征)的发病机制简要作一综述。 展开更多
关键词 CYLD1 毛发上皮瘤 家族圆柱 Brook-Spiegler综合征
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Three-dimensional numerical simulation of the flow past a circular cylinder based on LES method 被引量:1
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作者 陈海龙 戴绍士 +1 位作者 李佳 姚熊亮 《Journal of Marine Science and Application》 2009年第2期110-116,共7页
The hydrodynamic characteristics of a rigid, single, circular cylinder in a three dimensional, incompressible, uniform cross flow were calculated using the large-eddy simulation method of CFX5. Solutions to the three ... The hydrodynamic characteristics of a rigid, single, circular cylinder in a three dimensional, incompressible, uniform cross flow were calculated using the large-eddy simulation method of CFX5. Solutions to the three dimensional N-S equations were obtained by the finite volume method. The focus of this numerical simulation was to research the characteristics of pressure distribution (drag and litt forces) and vortex tubes at high Reynolds numbers. The results of the calculations showed that the forces at every section in the spanwise direction of the cylinder were symmetrical about the middle section and smaller than the forces calculated in two dimensional cases. Moreover, the flow around the cylinder obviously presents three dimensional characteristics. 展开更多
关键词 LES method three-dimensional flow past circular cylinder hydrodynamic characteristics
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Optimization and experimental research on a new-type short cylindrical cup-shaped harmonic reducer 被引量:8
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作者 高海波 庄红超 +3 位作者 李志刚 邓宗全 丁亮 刘振 《Journal of Central South University》 SCIE EI CAS 2012年第7期1869-1882,共14页
In order to obtain a new-type short cylindrical cup-shaped flexspline that can be applied to space mechanisms,the APDL language of ANSYS software was employed to develop a parameterized equivalent contact model betwee... In order to obtain a new-type short cylindrical cup-shaped flexspline that can be applied to space mechanisms,the APDL language of ANSYS software was employed to develop a parameterized equivalent contact model between a flexspline and a wave generator. The validity of the parameterized equivalent contact model was verified by comparing the results of the analytic value of the contact model and the value calculated by the theoretical formula. The curvilinear trend of stress was obtained by changing the structural parameter of the flexspline. Based on the curvilinear trend of stress,multi-objective optimizations of key structural parameters were achieved. Flexspline,wave generator,and circular spline of a new 32-type short cylindrical cup-shaped harmonic reducer were designed and manufactured. A performance test bench to carry out tests on the harmonic reducer was designed. Contrast experiments were implemented to determine the efficiency of the new 32-type short cylindrical cup-shaped harmonic reducer and the conventional 32-type harmonic reducer under different conditions. The experimental results reveal that there is approximately equality in terms of efficiency between the new 32-type short cylindrical cup-shaped harmonic reducer and the conventional 32-type harmonic reducer. The volume of the flexspline of the new 32-type short cylindrical cup-shaped harmonic reducer is reduced by approximately 30% through multi-objective optimization. When the new 32-type short cylindrical cup-shaped harmonic reducer is used on the wheel of a rover prototype,the mass of the wheel hub is decreased by 0.42 kg. Test analysis of wheel motion verifies that the new 32-type short cylindrical cup-shaped harmonic reducer can meet the requirements regarding bearing capacity and efficiency. 展开更多
关键词 harmonic drive FLEXSPLINE structural parameter multi-objective optimization
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Dynamic anti-plane characteristic on an infinite piezoelectric medium with a movable rigid cylindrical inclusion 被引量:1
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作者 SONG Tian-shu SUN Li-li YU Zhen-dong 《Journal of Marine Science and Application》 2005年第2期61-64,共4页
Scattering and dynamic stress concentrations of time harmonic SH-wave in an infinite elastic piezoelectric medium with a movable rigid cylindrical inclusion are studied in this paper with the help of complex variable ... Scattering and dynamic stress concentrations of time harmonic SH-wave in an infinite elastic piezoelectric medium with a movable rigid cylindrical inclusion are studied in this paper with the help of complex variable and wave function expansion method. The relations that a movable rigid cylindrical inclusion depends on intensity of incident wave and electric field are revealed. The expressions of dynamic stress at the edge of the inclusion are obtained. Numerical calculations are made with different wave numbers and different piezoelectric characteristic parameters. The calculating results show that dynamic stress concentrations at the edge of the inclusion have linear dependence on the incident electric field. And dynamic analyses are very important for an infinite piezoelectric medium with a movable rigid cylindrical inclusion at larger piezoelectric characteristic parameters. 展开更多
关键词 piezoelectric medium movable rigid cylindrical inclusion scattering of SH-wave dynamic stress concentration
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Natural frequency characteristics of thin-walled homogeneous and manifold layered cylindrical shells under pressure using energy method 被引量:2
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作者 M.R.Isvandzibaei Hishamuddin Jamaluddin Raja Ishak Raja Hamzah 《Journal of Central South University》 SCIE EI CAS 2014年第2期521-532,共12页
Energy method for the vibration of two types of cylindrical shells,namely thin-walled homogeneous isotropic and manifold layered isotropic cylindrical shells under uniform external lateral pressure is presented.The st... Energy method for the vibration of two types of cylindrical shells,namely thin-walled homogeneous isotropic and manifold layered isotropic cylindrical shells under uniform external lateral pressure is presented.The study is carried out based on strain-displacement relationship from Love's shell theory with beam functions as axial modal function.A manifold layered cylindrical shell configuration is formed by three layers of isotropic material where the inner and outer layers are stainless steel and the middle layer is aluminum.The homogeneous cylindrical shell is made-up of isotropic one layer with stainless steel.The governing equations with uniform external lateral pressure for homogeneous isotropic and manifold layered isotropic cylindrical shells are obtained using energy functional by the Lagrangian function with Rayleigh-Ritz method.The boundary conditions that are presented at the end conditions of the cylindrical shell are simply supported-simply supported,clamped-clamped and free-free.The influences of uniform external lateral pressure and symmetrical boundary conditions on the natural frequency characteristics for both homogeneous and manifold layered isotropic cylindrical shells are examined.For all boundary conditions considered,the natural frequency of both cylindrical shells with symmetric uniform lateral pressure increases as h/R ratio increases and those considering natural frequency of the both cylindrical shells with symmetric uniform lateral pressure decrease as L/R ratio increases. 展开更多
关键词 cylindrical shell manifold layered PRESSURE energy method
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Active Control of Structurally Radiated Sound from an Elastic Cylindrical Shell 被引量:2
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作者 靳国永 刘小玲 刘志刚 《Journal of Marine Science and Application》 2011年第1期88-97,共10页
A numerical and experimental study was presented on active control of structurally radiated sound from an elastic cylindrical shell.An analytical model was developed for the active structural acoustic control (ASAC) o... A numerical and experimental study was presented on active control of structurally radiated sound from an elastic cylindrical shell.An analytical model was developed for the active structural acoustic control (ASAC) of the cylindrical shell.Both global and local control strategies were considered.The optimal control forces corresponding to each control strategy were obtained by using the linear quadratic optimal control theory.Numerical simulations were performed to examine and analyze the control performance under different control strategies.The results show that global sound attenuation of the cylindrical shell at resonance frequencies can be achieved by using point force as the control input of the ASAC system.Better control performance can be obtained under the control strategy of minimization of the radiated sound power.However,control spillover may occur at off-resonance frequencies with the control strategy of structural kinetic energy minimization in terms of the radiated sound power.Considerable levels of global sound attenuation can also be achieved in the on-resonance cases with the local control strategy,i.e.,minimization of the mean-square velocity of finite discrete locations.An ASAC experiment using an FXLMS algorithm was implemented,agreement was observed between the numerical and experimental results,and successful attenuation of structural vibration and radiated sound was achieved. 展开更多
关键词 cylindrical shell radiated sound power active structural acoustic control (ASAC) FXLMS algorithm
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Deformation inhomogeneity due to sample-anvil friction in cylindrical compression test 被引量:3
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作者 Xian-jue YE Xiao-juan GONG +2 位作者 Biao-biao YANG Yun-ping LI Yan NIE 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2019年第2期279-286,共8页
Finite element(FEM)analysis was used to systematically evaluate the inhomogeneity of deformation in cylindrical samples with various sample-anvil friction coefficients,m.It was found that the level of friction strongl... Finite element(FEM)analysis was used to systematically evaluate the inhomogeneity of deformation in cylindrical samples with various sample-anvil friction coefficients,m.It was found that the level of friction strongly influences the deformation homogeneity,which increases significantly with the friction coefficient although the overall geometry of the samples almost remains the same when m >0.4.The position,at which the effective strain along the maximum radial direction in a compressed sample is equal to the equivalent strain of the sample,does not vary greatly with respect to both equivalent strain of the sample and m.Hardness measurements of compressed cylindrical 5056B Al alloy samples revealed a change of effective strain distribution similar to that revealed by FEM analysis.There exists a quantitative relationship between the hardness and the effective strain if no recrystallization or recovery occurs during the compression process. 展开更多
关键词 compression friction coefficient barreling cylinder deformation inhomogeneity
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Formability improvement and blank shape definition for deep drawing of cylindrical cup with complex curve profile from SPCC sheets using FEM 被引量:3
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作者 Duc-Toan Nguyen Duy-Khoe Dinh +2 位作者 Hong-Minh Thi Nguyen Tien-Long Banh Young-Suk Kim 《Journal of Central South University》 SCIE EI CAS 2014年第1期27-34,共8页
In the current work, to predict and improve the formability of deep drawing process for steel plate cold rolled commercial grade (SPCC) sheets, three parameters including the blanking force, the die and punch comer ... In the current work, to predict and improve the formability of deep drawing process for steel plate cold rolled commercial grade (SPCC) sheets, three parameters including the blanking force, the die and punch comer radius were considered. The experimental plan according to Taguchi's orthogonal array was coupled with the finite element method (FEM) simulations. Firstly, the data from the test of stress-strain and forming limit curves were used as input into ABAQUS/Explicit finite element code to predict the failure occurrence of deep drawing process. The three parameters were then validated to establish their effects on the press formability. The optimum case found via simulation was finally confirmed through an experiment. In order to obtain the complex curve profile of cup shape after deep drawing, the anisotropic behavior of earring phenomenon was modeled and implemented into FEM. After such phenomenon was correctly predicted, an error metric compared with design curve was then measured. 展开更多
关键词 finite element method SPCC DEEP-DRAWING forming limit diagram criterion Taguchi's method earring prediction
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Influence of lateral initial pressure on axisymmetric wave propagation in hollow cylinder based on first power hypo-elastic model 被引量:1
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作者 胡文韬 夏唐代 陈炜昀 《Journal of Central South University》 SCIE EI CAS 2014年第2期753-760,共8页
Influence of identical applied initial pressures on the radial surfaces of a hollow cylinder which is compose of materials with first power hypo-elastic constitutive model was investigated.The basic equations of the p... Influence of identical applied initial pressures on the radial surfaces of a hollow cylinder which is compose of materials with first power hypo-elastic constitutive model was investigated.The basic equations of the problem were built up based on the framework of piecewise homogeneous body model with the use of three-dimensional linearized theory of elastic waves in initially stressed bodies(TLTEWISB).With the method proposed previously,this problem was then solved numerically.Moreover,the dispersion group velocity of the lowest order mode with different initial pressures was also studied.It can be concluded that the initial pressure and the geometry parameters will induce considerable changes of different degrees in dispersive relation between phase velocity and wave number in opposite trend(positive in initial pressure and negative in thickness). 展开更多
关键词 initial pressure TLTEWISB first power hypo-elastic model dispersive relation
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The bending vibration response and approximate calculation of elastic cylindrical shell 被引量:1
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作者 CHEN Xiao-li SHENG Mei-ping HE Chen 《Journal of Marine Science and Application》 2006年第2期6-12,共7页
Useful structure characteristics of elastic cylindrical shells have led them to being widely applied in virtual projects,so it is important to conduct vibration research on the shells and find it’s a simpler correspo... Useful structure characteristics of elastic cylindrical shells have led them to being widely applied in virtual projects,so it is important to conduct vibration research on the shells and find it’s a simpler corresponding compact calculation method. Utilising the input and transfer point mobility of a thin plate structure, a theoretical expression of the cylindrical shell’s bending vibration responsewas deduced and numerical simulations were done to simplify the theoretical expression within an acceptable error margin, greatly reducing the amount of computations. Furthermore, whole vibration response distributions of the cylindrical shell were analyzed. It was found thathe vibration energy propagates in helical form under mono-frequency excitation, while under bandwidth frequency excitation, it attenuates around in term of fluctuation.The axial attenuation rate of the vibration energy is larger than the circumferential attenuation rate. 展开更多
关键词 cylindrical shell MOBILITY vibration response
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CYLD基因抗肿瘤机制及其在皮肤附属器肿瘤中的研究进展
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作者 朱家平 姜祎群 《肿瘤综合治疗电子杂志》 2022年第4期6-9,共4页
CYLD基因是位于16号染色体的抑癌基因,其突变可导致家族性圆柱瘤病等遗传性皮肤附属器肿瘤。近来研究发现CYLD基因编码一种K63特异性去泛素化酶,通过作用于核因子κB(nuclear factor-κB,NF-κB)通路中的TRAF2、NEMO等位点抑制NF-κB通... CYLD基因是位于16号染色体的抑癌基因,其突变可导致家族性圆柱瘤病等遗传性皮肤附属器肿瘤。近来研究发现CYLD基因编码一种K63特异性去泛素化酶,通过作用于核因子κB(nuclear factor-κB,NF-κB)通路中的TRAF2、NEMO等位点抑制NF-κB通路活化,同时亦参与调节JNK、Hedgehog等信号通路,发挥抗肿瘤效应。本文回顾并总结了CYLD基因发挥抗肿瘤效应的具体分子机制,讨论了CYLD基因突变在其所致皮肤附属器肿瘤表型发展中的意义。 展开更多
关键词 CYLD基因 家族圆柱瘤病 多发家族毛发上皮瘤 核因子ΚB
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A General Method to Study the Sound Radiation of a Finite Cylindrical Shell Based on Elastic Theory
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作者 Junjie Zhang Chunhui Yuan +1 位作者 Xianming Zhu Tianyun Li 《Journal of Marine Science and Application》 2012年第2期258-264,共7页
A general method was proposed to study the sound and vibration of a finite cylindrical shell with elastic theory. This method was developed through comprehensive analysis of the uncoupled Helmholtz equation obtained b... A general method was proposed to study the sound and vibration of a finite cylindrical shell with elastic theory. This method was developed through comprehensive analysis of the uncoupled Helmholtz equation obtained by the decomposition of elastic equations and the structure of the solution of a finite cylindrical shell analyzed by thin shell theory. The proposed method is theoretically suitable for arbitrary thickness of the shell and any frequency. Also, the results obtained through the method can be used to determine the range of application of the thin shell theory. Furthermore, the proposed method can deal with the problems limited by the thin shell theory. Additionally, the method can be suitable for several types of complex cylindrical shell such as the ring-stiffened cylindrical shell, damped cylindrical shell, and double cylindrical shell. 展开更多
关键词 finite cylindrical shell elastic theory sound radiation thin shell theory
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Hawking Radiation of Charged Particles via Tunneling from a Cylindrically Symmetric Black Hole in Anti-de Sitter Space-Time
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作者 YANG Shu-Zheng JIANG Qing-Quan LI Hui-Ling 《Communications in Theoretical Physics》 SCIE CAS CSCD 2006年第4X期643-646,共4页
Applying Parikh-Wilzcek's semi-classical quantum tunneling model, we study the Hawking radiation of charged particles as tunneling from the event horizon of a cylindrically symmetric black hole in anti-de Sitter spac... Applying Parikh-Wilzcek's semi-classical quantum tunneling model, we study the Hawking radiation of charged particles as tunneling from the event horizon of a cylindrically symmetric black hole in anti-de Sitter space-time. The derived result shows that the tunneling rate of charged particles is related to the change of Bekenstein-Hawking entropy and that the radiation spectrum is not strictly pure thermal after taking the black hole background dynamical and self-gravitation interaction into account, but is consistent with the underlying unitary theory. 展开更多
关键词 cylindrically symmetric black hole Bekenstein-Hawking entropy energy conservation charge conservation tunneling rate
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