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两性药物土霉素的传感电极及其选择性规律 被引量:3
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作者 姚守拙 肖俊 聂利华 《高等学校化学学报》 SCIE EI CAS 1988年第6期637-639,共3页
用离子选择性电极测定药物,研究甚多,其中大都是生物碱、季铵等类碱性药物,与非水滴定等法相比、优点并不显著,至于抗生素类药物,常用微生物法分析,缺点很多,本文报告土霉素的阳离子型与阴离子型电极,探讨了选择性规律,电极在pH1.6~3.2... 用离子选择性电极测定药物,研究甚多,其中大都是生物碱、季铵等类碱性药物,与非水滴定等法相比、优点并不显著,至于抗生素类药物,常用微生物法分析,缺点很多,本文报告土霉素的阳离子型与阴离子型电极,探讨了选择性规律,电极在pH1.6~3.2与pH8.0~11.0分别响应含质子化二甲胺基的土霉素一价阳离子与含离解B环烯醇基的土霉素一价阴离子,1gKij与季铵离子势及诱导效应指数有良好的线性关系,符合1gKij=a+bI-cZ/R,极限值7.07。 展开更多
关键词 土霉素传感电极 土霉素测定 电极选择性
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Determination of Tetracycline and Oxytetracycline Residues in Honey by High Performance Liquid Chromatography 被引量:1
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作者 Shaif Mohammed Kasem Saleh Amer Mohammed Mussaed Fadhl Mohammed Al-Hariri 《Journal of Agricultural Science and Technology(B)》 2016年第2期135-139,共5页
Honey is being used as a pure natural and as an ingredient in many foods, pharmaceuticals and cosmetics than ever before, so honey testing has become essential to maintain its healthful characteristics and protect pub... Honey is being used as a pure natural and as an ingredient in many foods, pharmaceuticals and cosmetics than ever before, so honey testing has become essential to maintain its healthful characteristics and protect public health. Tetracyclines (TCs) are used for the treatment or prevention of American and European foul broad in bee colonies which are caused especially by two species of bacteria--Paenibacillus larvae and Melissococcus pluton. The present study aimed to determine the tetracycline residues in different types of local and imported honey. The reversed-phase high performance liquid chromatography (HPLC) with ultraviolet detection (UV) was used. Tetracycline and oxytetracycline were extracted from honey with 0.01 M sodium succinate buffer. Of the examined samples, 31.25% and 12.50% had these oxytetracycline and tetracycline residues, respectively. It was observed that all the samples studied have been reported residues of tetracycline and oxytetracycline more than international standards of maximum residue limit (MRLs). 展开更多
关键词 HONEY antibiotic residues TETRACYCLINE OXYTETRACYCLINE HPLC Yemen.
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