目的:观察团体改良限制-诱导运动疗法(Group modified constraint-induced movement therapy,gmCIMT)结合镜像疗法对脑卒中偏瘫患者症状改善情况的影响。方法:将本院2020年2月至2021年12月120例缺血性脑卒中单侧肢体瘫痪患者随机分为观...目的:观察团体改良限制-诱导运动疗法(Group modified constraint-induced movement therapy,gmCIMT)结合镜像疗法对脑卒中偏瘫患者症状改善情况的影响。方法:将本院2020年2月至2021年12月120例缺血性脑卒中单侧肢体瘫痪患者随机分为观察组和对照组,各60例。对照组采用常规物理治疗,观察组在对照组基础上采取gmCIMT结合镜像疗法。治疗8 w后对比两组疗效采用量表评分分析运动功能康复情况以及对比两组大脑皮质μ波抑制指数。结果:观察组治疗有效率高于对照组(P<0.05);两组治疗后运动功能量表评分,Cz、CPZ、CP3以及C3区域的大脑皮质μ波抑制指数较治疗前升高(P<0.05),观察组治疗后上述指标均高于对照组(P<0.05)。结论:gmCIMT结合镜像疗法治疗脑卒中偏瘫患者疗效确切,可提高大脑皮质μ波抑制指数,改善运动功能。展开更多
AIM To explore regional systolic strain of midwall and endocardial segments using speckle tracking echocardiography in patients with apical hypertrophic cardiomyopathy(HCM).METHODS We prospectively assessed 20 patient...AIM To explore regional systolic strain of midwall and endocardial segments using speckle tracking echocardiography in patients with apical hypertrophic cardiomyopathy(HCM).METHODS We prospectively assessed 20 patients(mean age 53 ± 16 years,range:18-81 years,10 were male),with apical HCM. We measured global longitudinal peak systolic strain(GLPSS) in the midwall and endocardium of the left ventricle. RESULTS The diastolic thickness of the 4 apical segments was 16.25 ± 2.75 mm. All patients had a normal global systolicfunction with a fractional shortening of 50% ± 8%. In spite of supernormal left ventricular(LV) systolic function,midwall GLPSS was decreased in all patients,more in the apical(-7.3% ±-8.8%) than in basal segments(-15.5% ±-6.93%),while endocardial GLPPS was significantly greater and reached normal values(apical:-22.8% ±-7.8%,basal:-17.9% ±-7.5%). CONCLUSION This study shows that two-dimensional strain was decreased mainly confined to the mesocardium,while endocardium myocardial deformation was preserved in HCM and allowed to identify subclinical LV dysfunction. This transmural heterogeneity in systolic strain had not been previously described in HCM and could be explained by the distribution of myofibrillar disarray in deep myocardial areas. The clinical application of this novel finding may help further understanding of the pathophysiology of HCM.展开更多
文摘AIM To explore regional systolic strain of midwall and endocardial segments using speckle tracking echocardiography in patients with apical hypertrophic cardiomyopathy(HCM).METHODS We prospectively assessed 20 patients(mean age 53 ± 16 years,range:18-81 years,10 were male),with apical HCM. We measured global longitudinal peak systolic strain(GLPSS) in the midwall and endocardium of the left ventricle. RESULTS The diastolic thickness of the 4 apical segments was 16.25 ± 2.75 mm. All patients had a normal global systolicfunction with a fractional shortening of 50% ± 8%. In spite of supernormal left ventricular(LV) systolic function,midwall GLPSS was decreased in all patients,more in the apical(-7.3% ±-8.8%) than in basal segments(-15.5% ±-6.93%),while endocardial GLPPS was significantly greater and reached normal values(apical:-22.8% ±-7.8%,basal:-17.9% ±-7.5%). CONCLUSION This study shows that two-dimensional strain was decreased mainly confined to the mesocardium,while endocardium myocardial deformation was preserved in HCM and allowed to identify subclinical LV dysfunction. This transmural heterogeneity in systolic strain had not been previously described in HCM and could be explained by the distribution of myofibrillar disarray in deep myocardial areas. The clinical application of this novel finding may help further understanding of the pathophysiology of HCM.
