AIM： To investigate the incidence and mortality of gastric cancer （GC） in Zhuanghe region, northeast China and the influencing factors for their changing trends.METHODS： All new cancer cases and deaths registered ...AIM： To investigate the incidence and mortality of gastric cancer （GC） in Zhuanghe region, northeast China and the influencing factors for their changing trends.METHODS： All new cancer cases and deaths registered from 2005 to 2010 in Zhuanghe County were reviewed. The annual GC cases, constituent ratio, crude rates,age-standardized rates, their sex and age distribution and temporal trends were assessed. The method of annual percentage change （APC） was used to estimate the trends of GC.RESULTS： Altogether 2634 new cases of GC and 1722 related deaths were registered, which accounted for 21.04% and 19.13% of all cancer-related incidence and deaths, respectively. The age-standardized incidence rate steadily decreased from 57.48 in 2005 to 44.53 in 2010 per 10^5 males, and from 18.13 to 14.70 per 10s females, resulting in a APC of -5.81% for males and -2.89% for females over the entire period. The magnitude of APC in GC mortality amounted to -11.09% and -15.23%, respectively, as the agestandardized mortality rate steadily decreased from 42.08 in 2005 to 23.71 in 2010 per 10^5 males, and from 23.86 to 10.78 per 10^5 females. Females had a significantly lower incidence （a male/female ratio 2.80, P 〈 0.001） and mortality （a male/female ratio 2.30, P 〈 0.001）. In both genders, the peak incidence and mortality occurred in the 80-84 years age group. The age-standardized mortality/incidence ratio also decreased from the peak of 0.73 in 2005 to 0.53 in 2010 for males, and from 1.32 to 0.73 for females.CONCLUSION： Encouraging declines of incidence and mortality of GC were observed in Zhuanghe region between 2005 and 2010, possibly due to the economic development and efficient GC control strategies.展开更多
AIM： To determine the effect of body mass index （BMI） on the characteristics and overall outcome of colon cancer in Taiwan. METHODS： From January 1995 to July 2003, 2138 patients with colon cancer were enrolled in...AIM： To determine the effect of body mass index （BMI） on the characteristics and overall outcome of colon cancer in Taiwan. METHODS： From January 1995 to July 2003, 2138 patients with colon cancer were enrolled in this study. BMI categories （in kg/m2） were established according to the classification of the Department of Health of Tai- wan. Postoperative morbidities and mortality, and survival analysis including overall survival （OS）, disease- free survival （DFS）, and cancer-specific survival （CSS） were compared across the BMI categories.27 kg/m2） patients. Being female, apparently anemic, hypoalbuminemic, and having body weight loss was more likely among underweight patients than among the other patients （P 〈 0.001）. Underweight patients had higher mortality rate （P = 0.00.7） and lower OS （P 〈 0.001） and DFS （P = 0.002） than the other pa- tients. OS and DFS did not differ significantly between normal-weight, overweight, and obese patients, while CSS did not differ significantly with the BMI category. CONCLUSION： In Taiwan, BMI does not significantly affect colon-CSS. Underweight patients had a higher rate of surgical mortality and a worse OS and DFS than the other patients. Obesity does not predict a worse survival.展开更多
Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophage...Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophageal cancer were provid- ed by Huai'an Cancer Registry, and the epidemiological characteristics of the disease were analyzed. Results: Esophageal cancer was not only the first most common cancer, but also the leading cause of cancer death in Huai'an area. The crude and standardized incidence rates were 62.91/10 5 and 49.92/10 5 , and the crude and standardized mortality rates were 46.75/10 5 and 36.87/10 5 , respectively. The sex ratio (male-female) was 1.69:1 in incidence, and the incidence increased in people aged 40 years and over, reaching the peak at the ages of 70-75 years. The mortality rate was at low level under the age of 50 years, but increased after the age of 50 years, reaching the peak at the age of 75-85 years. Incidence and mortality rates varied regionally with the highest rate found in Chuzhou district (90.76/10 5 and 67.17/10 5 ) and lowest rate observed in Qinghe district (32.41/10 5 and 8.75/10 5 ). Conclusion: Esophageal cancer is the major burden of cancer in Huai'an area, and has marked geographic distribution difference. The key period of age for screening and prevention of the disease is 55-85 years old.展开更多
基金Supported by Grants from the Tenth Five-Year Program for National Scientific Key Project of China,No.2004BA703B06-2973 National Basic Research Development Program of China,No.2010CB529304the funds for scientific research fromthe Financial Department of Liaoning Province,China,No.2008-621
文摘AIM： To investigate the incidence and mortality of gastric cancer （GC） in Zhuanghe region, northeast China and the influencing factors for their changing trends.METHODS： All new cancer cases and deaths registered from 2005 to 2010 in Zhuanghe County were reviewed. The annual GC cases, constituent ratio, crude rates,age-standardized rates, their sex and age distribution and temporal trends were assessed. The method of annual percentage change （APC） was used to estimate the trends of GC.RESULTS： Altogether 2634 new cases of GC and 1722 related deaths were registered, which accounted for 21.04% and 19.13% of all cancer-related incidence and deaths, respectively. The age-standardized incidence rate steadily decreased from 57.48 in 2005 to 44.53 in 2010 per 10^5 males, and from 18.13 to 14.70 per 10s females, resulting in a APC of -5.81% for males and -2.89% for females over the entire period. The magnitude of APC in GC mortality amounted to -11.09% and -15.23%, respectively, as the agestandardized mortality rate steadily decreased from 42.08 in 2005 to 23.71 in 2010 per 10^5 males, and from 23.86 to 10.78 per 10^5 females. Females had a significantly lower incidence （a male/female ratio 2.80, P 〈 0.001） and mortality （a male/female ratio 2.30, P 〈 0.001）. In both genders, the peak incidence and mortality occurred in the 80-84 years age group. The age-standardized mortality/incidence ratio also decreased from the peak of 0.73 in 2005 to 0.53 in 2010 for males, and from 1.32 to 0.73 for females.CONCLUSION： Encouraging declines of incidence and mortality of GC were observed in Zhuanghe region between 2005 and 2010, possibly due to the economic development and efficient GC control strategies.
文摘AIM： To determine the effect of body mass index （BMI） on the characteristics and overall outcome of colon cancer in Taiwan. METHODS： From January 1995 to July 2003, 2138 patients with colon cancer were enrolled in this study. BMI categories （in kg/m2） were established according to the classification of the Department of Health of Tai- wan. Postoperative morbidities and mortality, and survival analysis including overall survival （OS）, disease- free survival （DFS）, and cancer-specific survival （CSS） were compared across the BMI categories.27 kg/m2） patients. Being female, apparently anemic, hypoalbuminemic, and having body weight loss was more likely among underweight patients than among the other patients （P 〈 0.001）. Underweight patients had higher mortality rate （P = 0.00.7） and lower OS （P 〈 0.001） and DFS （P = 0.002） than the other pa- tients. OS and DFS did not differ significantly between normal-weight, overweight, and obese patients, while CSS did not differ significantly with the BMI category. CONCLUSION： In Taiwan, BMI does not significantly affect colon-CSS. Underweight patients had a higher rate of surgical mortality and a worse OS and DFS than the other patients. Obesity does not predict a worse survival.
基金Supported by grants from the Medical Science and Technology Innovation Foundation of Nanjing Military Command of Chinese People’s Liberation Army (No. 08MA036)Jiangsu Province Preventive Medicine Foundation (No. YZ201008)
文摘Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophageal cancer were provid- ed by Huai'an Cancer Registry, and the epidemiological characteristics of the disease were analyzed. Results: Esophageal cancer was not only the first most common cancer, but also the leading cause of cancer death in Huai'an area. The crude and standardized incidence rates were 62.91/10 5 and 49.92/10 5 , and the crude and standardized mortality rates were 46.75/10 5 and 36.87/10 5 , respectively. The sex ratio (male-female) was 1.69:1 in incidence, and the incidence increased in people aged 40 years and over, reaching the peak at the ages of 70-75 years. The mortality rate was at low level under the age of 50 years, but increased after the age of 50 years, reaching the peak at the age of 75-85 years. Incidence and mortality rates varied regionally with the highest rate found in Chuzhou district (90.76/10 5 and 67.17/10 5 ) and lowest rate observed in Qinghe district (32.41/10 5 and 8.75/10 5 ). Conclusion: Esophageal cancer is the major burden of cancer in Huai'an area, and has marked geographic distribution difference. The key period of age for screening and prevention of the disease is 55-85 years old.
