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《灯火阑珊》:香港地区地域文化变迁的电影书写
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作者 李红梅 《电影文学》 北大核心 2023年第22期141-143,共3页
2023年是香港地区电影近年来的一次“小阳春”,很多值得关注的优秀电影作品接二连三地走到观众的面前。这其中,曾宪宁导演的《灯火阑珊》就广受好评并且斩获票房佳绩。影片将香港地区的时代变迁和独特的地域文化特征巧妙融入市井故事之... 2023年是香港地区电影近年来的一次“小阳春”,很多值得关注的优秀电影作品接二连三地走到观众的面前。这其中,曾宪宁导演的《灯火阑珊》就广受好评并且斩获票房佳绩。影片将香港地区的时代变迁和独特的地域文化特征巧妙融入市井故事之中,不仅体现了香港地区电影的创作共性、丰富了香港地区电影的创作空间,也为研究香港地区电影的发展提供了有益的帮助。 展开更多
关键词 香港地区地域文化 香港地区电影 《灯火阑珊》
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东北地区地域性建筑文化研究 被引量:2
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作者 宁芙儿 于治均 《美与时代(城市)》 2016年第2期17-17,共1页
东北地区地域建筑文化带有鲜明特色的中国传统建筑文化的缩影,具有开放性、可塑性、包容性和复杂性等特点。在对东北地区地域建筑文化背景基础上进行简述,提出应从乡土式洋化建筑的保护与利用等方面加强对东北地域建筑文化的研究。
关键词 东北地区地域文化 乡土式洋化建筑 建筑文化
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谈南方地区老年公寓套型地域性设计
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作者 王跃 蔡忠田 《建筑与设备》 2012年第3期16-18,共3页
建筑设计首先应该遵循一个基本原则:尊重环境、尊重历史、尊重当地生活习俗、满足现代生活需求同时又适应现代经济社会发展。本文的研究基于前人工作的基础之上对我国南方湖南和海南两个地区的气候、人文、地形地貌等元素分析并对当地... 建筑设计首先应该遵循一个基本原则:尊重环境、尊重历史、尊重当地生活习俗、满足现代生活需求同时又适应现代经济社会发展。本文的研究基于前人工作的基础之上对我国南方湖南和海南两个地区的气候、人文、地形地貌等元素分析并对当地的老年公寓进行考察。通过分析比较。探索出南方地区老年公寓套型地域性设计的方向。 展开更多
关键词 老年公寓南方地区地域性套型
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河套地区室内设计地域性特色
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作者 郝淑惠 《内蒙古科技与经济》 2006年第06S期69-70,共2页
河套地区的室内设计,往往盲目复制现代经济发达地区的设计符号,丧失了鲜活的地域性。河套文化是游牧文化与黄河文化融合的产物,有着鲜明的地域特色。历史上数次大移民,尤其是清末民初晋、陕二地向河套地区移民,开发了河套地区的农耕文化... 河套地区的室内设计,往往盲目复制现代经济发达地区的设计符号,丧失了鲜活的地域性。河套文化是游牧文化与黄河文化融合的产物,有着鲜明的地域特色。历史上数次大移民,尤其是清末民初晋、陕二地向河套地区移民,开发了河套地区的农耕文化,河套民居随之从蒙古包为主逐步迁移到以晋、陕特色民居为主,形成了独特的室内设计风格。继承、发扬传统室内设计风格,可使河套地区的的室内设计继续保持自己的特色,在当代室内设计领域独树一帜。 展开更多
关键词 河套地区室内设计地域 移民 蒙古包 陕北民窑
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天津旅游纪念品设计的地域性文化表现研究 被引量:1
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作者 张媛 叶倩 《设计》 2013年第11期37-38,共2页
在旅游业日益发达的今天,人们对于旅游的需求逐步由观光旅游转向人文旅游。旅游纪念品作为旅游行业中一个重要的组成部分,充当了物质和精神的双重载体。通过对现存天津地区旅游纪念品市场的调查和分析,发现产品同质化严重、缺乏地域文... 在旅游业日益发达的今天,人们对于旅游的需求逐步由观光旅游转向人文旅游。旅游纪念品作为旅游行业中一个重要的组成部分,充当了物质和精神的双重载体。通过对现存天津地区旅游纪念品市场的调查和分析,发现产品同质化严重、缺乏地域文化等不足,在对地域文化进行概括、归类的基础上,力图寻找设计突破点。如何更好的把地域性文化符号与天津地区旅游纪念品结合起来,对于发展该地区旅游业,提升天津地区城市文化形象都起到至关重要的作用。 展开更多
关键词 天津地区旅游纪念品地域性文化城市形象
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日本城市的区域划分
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作者 杜钢建 刘杰 《小城镇建设》 2000年第11期46-48,共3页
日本城市规划法及有关法律,是根据区域的特点和管制的需要,从不同角度,规定城市规划区域的分类形式及其种类。分位形式有四种。
关键词 城市规划区域 日本 市街化区域 地域地区
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A New Approach to Measurement of Regional Inequality in Particular Directions 被引量:19
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作者 WANG Yang FANG Chuanglin +1 位作者 XIU Chunliang LIU Daqian 《Chinese Geographical Science》 SCIE CSCD 2012年第6期705-717,共13页
Regional inequality is a core issue in geography,and it can be measured by several approaches and indexes.However,the global inequality measures can not reflect regional characteristics in terms of spatiality and non-... Regional inequality is a core issue in geography,and it can be measured by several approaches and indexes.However,the global inequality measures can not reflect regional characteristics in terms of spatiality and non-mobility,as well as correctly explore regional inequality in particular directions.Although conventional between-group inequality indexes can measure the inequality in particular directions,they can not reflect the reversals of regional patterns and changes of within-group patterns.Therefore,we set forth a new approach to measure regional inequality in particular directions,which is applicable to geographic field.Based on grouping,we established a new index to measure regional inequality in particular directions named Particular Direction Inequality index(PDI index),which is comprised of between-group inequality of all data and between-group average gap.It can reflect regional spatiality and non-mobility,judge the main direction of regional inequality,and capture the changes and reversals of regional patterns.We used the PDI index to measure the changes of regional inequality from 1952 to 2009 in China.The results show that:1) the main direction of China's regional inequality was between coastal areas and inland areas;the increasing extent of inequality between coastal areas and inland areas was higher than the global inequality;2) the PDI index can measure the between-region average gap,and is more sensitive to evolution of within-region patterns;3) the inequality between the northern China and the southern China has been decreasing from 1952 to 2009 and was reversed in 1994 and 1995. 展开更多
关键词 regional inequality inequality indexes PDI index particular directions China
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Revitalizing Old Industrial Base of Northeast China:Process, Policy and Challenge 被引量:8
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作者 ZHANG Pingyu 《Chinese Geographical Science》 SCIE CSCD 2008年第2期109-118,共10页
Northeast China is the largest old industrial base of China that endured persistent influence of the past planned economy system. This region has lost its leading place since the reform and opening up, and became a ba... Northeast China is the largest old industrial base of China that endured persistent influence of the past planned economy system. This region has lost its leading place since the reform and opening up, and became a backward region by contrast with the coastal areas. This paper elaborates the evolutionary process of the old industrial base of Northeast China, analyses the main reasons for the decline, gives a preliminary evaluation on the revitalizing polices in recent years, and points out major long-term challenges for future revitalization. It concludes that for Northeast China, a relative declining area: 1) it is indispensable to get the long-term policy support from the central government; 2) system reform and structure adjustment are the crucial strategies, particularly the reform of the large and medium state-owned enterprises; and devel-oping new industries is as important as upgrading traditional advantaged industries; 3) the local governments should play an indirect role, avoiding from any unnecessary intervention on economic activity; and 4) social security and investment climate must be improved simultaneously. In addition, the author stresses that the lack of knowledge on the nature of old industrial base had led to failures of the past initiatives, and revitalizing the old industrial base should be treated as a holis-tic regional project including economy growth, society progress and environment improvement. 展开更多
关键词 old industrial base regional revitalization regional policy Northeast China
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Mathematical Definitions of Point, Line and Area Symbols in Cartography 被引量:3
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作者 WEIWenzhan ZHONGYexun +1 位作者 PENGYueying ZHENGHongbo 《Geo-Spatial Information Science》 2003年第3期62-65,共4页
The line cartographic symbol located on the boundary and the point cartographic symbol located by single point are the main body and stress of the map. The cartographic symbols are divided into point, line and area sy... The line cartographic symbol located on the boundary and the point cartographic symbol located by single point are the main body and stress of the map. The cartographic symbols are divided into point, line and area symbol in cartography and traditional educational books, but up to now there is only qualitative description about the three kinds of symbols, there are not the mathematical definitions of point, line and area symbols. This paper tries to solve the problem. The authors propose the mathematical definition about point, line and area cartographic symbol according to the theory of topology and expound their dependence relation. 展开更多
关键词 point cartograrphic symbol line cartographic symbol area cartographicsymbol FIGURE
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Monitoring and Evaluation of Soil Changes Under Landuse of Different Patterns at a Small Regional Level in South China 被引量:11
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作者 WANGXIAOJU GONGZITONG 《Pedosphere》 SCIE CAS CSCD 1996年第4期373-378,共6页
MonitoringandEvaluationofSoilChangesUnderLanduseofDifferentPatternsataSmallRegionalLevelinSouthChinaWANGXIAO... MonitoringandEvaluationofSoilChangesUnderLanduseofDifferentPatternsataSmallRegionalLevelinSouthChinaWANGXIAOJUandGONGZITONG(I... 展开更多
关键词 EVALUATION geographical information system LANDUSE soil changes soil quality
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ANALYSIS ON SPATIAL DIFFERENCE OF LAND USECHANGE BASED ON PHYSICAL AND CULTURALLANDSCAPE ATTRIBUTES──A Case Study at Mongolian AutonomousCounty of Qian Gorlos, Jilin Province 被引量:3
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作者 HUANG Fang, LIU Xiang-nan, XU Hong-mei, ZHANG Shu-wen, ZHANG Yang-zhen (Changchun Institute of Geography, the Chinese Academy of Sciences, Changchun 130021, P. R. China School of Urban and Environmental Science, Northeast Normal University, Changchun 13 《Chinese Geographical Science》 SCIE CSCD 2001年第1期50-56,共7页
Land use changes are regarded as landscape pattern change driven by many interactive natural and social-economic factors. Different combination of physical geographical elements induced the difference of spatio-tempor... Land use changes are regarded as landscape pattern change driven by many interactive natural and social-economic factors. Different combination of physical geographical elements induced the difference of spatio-temporal pattern of land use change. There are four physical geographical regions in Mongolian Autonomou County of Qian Gorlos of Jilin Province. Based on spatial analysis and statistical analysis, we conclude that the primary pattern of land use and the tendency of land use changes are all different in four physical geographical regions. During 1987 – 1996, the dominant land use change processes were from grassland or forest to arableland, from unused land to paddy and grassland to unused land. Though land use change is mainly affected by social and economic condition in short period, the composite characters of physical geographical elements controls land use dynamic process. The relationship between land use dynamic process and the character of physical geographical units differ in different regions. Possible human impacts on land use change are explored with application of buffer areas of series distance along main roads and radius around main settlements. A few models are built to describe the relationship between land use spatial change rates and distance to road and settlements. According to our result, the relationship with the proximity to roads was a negative liner function, with the change rate decreasing rapidly when moving away from roads. Within a distance of less 7.5km from main traffic lines, land use changes occur red more. The bulk of grassland was apt to be opened up for cultivation around the settlements and the transformation from dryland to paddy occurred within the distance of 1km away from settlements. 展开更多
关键词 land use change physical geographic region land use dynamic process effective coefficient cultural landscape variable
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AN INSIGHT ON DRIVERS OF LAND USE CHANGE AT REGIONAL SCALE 被引量:2
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作者 SHAO Jing-an WEI Chao-fu XIE De-ti 《Chinese Geographical Science》 SCIE CSCD 2006年第2期176-182,共7页
The studies of driving forces of regional land use change (LUC) are to reveal the real motivation behind the LUC and its interacting mechanism, so as to simulate and predict the process of LUC. Presently, studies root... The studies of driving forces of regional land use change (LUC) are to reveal the real motivation behind the LUC and its interacting mechanism, so as to simulate and predict the process of LUC. Presently, studies rooting from different natural and socio-economic backgrounds and from different scales have deepened the people’s understanding and cognition to driving forces of regional LUC. Biophysical driving forces are relatively stable, and have the cumulating effects. Human driving forces are relatively active, and are main driving forces of short-term regional LUC. Existing regional LUC models can answer the three main problems: which contribution (why), which location (where) and what rate (when). But, regional land use system is defined as the self-organized system, usually affected by the cri- tical value area and sudden change, and controlled by different stages. To reduce the impact of critical threshold and break on land use system, the studies of LUC driving forces will aim at following priority areas: data linkage between remote sensing and no-remote sensing data; underlying driving force identification; driving factor quantification; driving factor scale dependence; and driving process integration simulation. 展开更多
关键词 land use change driving forces driving mechanism process simulation regional scale
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Estimation of Regional Evapotranspiration in Alpine Area and Its Response to Land Use Change:A Case Study in Three-River Headwaters Region of Qinghai-Tibet Plateau,China 被引量:6
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作者 LI Huixia LIU Guohua FU Bojie 《Chinese Geographical Science》 SCIE CSCD 2012年第4期437-449,共13页
Three-River Headwaters (TRH) region involved in this paper refers to the source region of the Changjiang (Yangtze) River, the Huanghe (Yellow) River and the Lancang River in China. Taking the TRH region of the Q... Three-River Headwaters (TRH) region involved in this paper refers to the source region of the Changjiang (Yangtze) River, the Huanghe (Yellow) River and the Lancang River in China. Taking the TRH region of the Qing- hai-Tibet Plateau as a case, the annual evapotranspiration (ET) model developed by Zhang et al. (2001) was applied to evaluate mean annual ET in the alpine area, and the response of annual ET to land use change was analyzed. The plant-available water coefficient (w) of Zhang's model was revised by using vegetation-temperature condition index (VTCI) before annual ET was calculated in alpine area. The future land use scenario, an input of ET model, was spa- tially simulated by using the conversion of land use and its effects at small regional extent (CLUE-S) to study the re- sponse of ET to land use change. Results show that the relative errors between the simulated ET and that calculated by using water balance equation were 3.81% and the index of agreement was 0.69. This indicates that Zhang's ET model based on revised plant-available water coefficient is a scientific and practical tool to estimate the annual ET in the al- pine area. The annual ET in 2000 in the study area was 221.2 ram, 11.6 mm more than that in 1980. Average annual ET decreased from southeast to northwest, but the change of annual ET between 1980 and 2000 increased from southeast to northwest. As a vast and sparsely populated area, the population in the TRH region was extremely unbalanced and land use change was concentrated in very small regions. Thus, land use change had little effect on total annual ET in the study area but a great impact on its spatial distribution, and the effect of land use change on ET decreased with in- creasing precipitation. ET was most sensitive to the interconversion between forest and unused land, and was least sen- sitive to the interconversion between cropland and low-covered grassland. 展开更多
关键词 evapotranspiration (ET) land use change plant-available water coefficient alpine area Three-RiverHeadwaters (TRH) region Qinghai-Tibet Plateau
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Revealing Storage-area Relationship of Open Water in Ungauged Subalpine Wetland-Napahai in Northwest Yunnan, China 被引量:7
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作者 LI Jie HU Jin-ming +4 位作者 DENG Wei HUANG Sheng-li JIA Hai-feng ZHU Chun-ling LUO Huai-xiu 《Journal of Mountain Science》 SCIE CSCD 2013年第4期553-563,共11页
Mountains and plateaus in Southwest China contain many subalpine and alpine wetlands, with signifieant hydroecological functions. But ungauged or poorly gauged eonditions limit the study and understanding of hydrologi... Mountains and plateaus in Southwest China contain many subalpine and alpine wetlands, with signifieant hydroecological functions. But ungauged or poorly gauged eonditions limit the study and understanding of hydrological regimes of these wetland types. This study selects an ungauged subalpine wetland - Napahai in Northwest Yunnan, China - as a case for developing a practical approach to revealing its storage-area relationship of open water. A Trimble R8 GNSS (Global Navigation Satellites Systems) RTK (Real-time Kinematic system) and sonar fathometer were used to survey fine- resolution elevation data and generate a digital elevation model of the Napahai Wetland. Forty-four Landsat images from 1987 to 2Oll were collected, and the Normalized Difference Water Index was used to classify open water features in the area. The area of open water in Napahai was ealculated for each phase. With these data and a developed conceptual model, the storage of open water for each phase was estimated using ArcGIS tools. Both storage and area of open water showed significant intra-annual and inter-annual variations. In the rainy season, the monthly change of average storage of open water in Napahai showed about 1-2 months lag behind mean monthly rainfall. The storage-area relationship of open water was well fit by a power function equation (R2=0.91, n=44). This study indicates that if detailedelevations are available for similarly ungauged subalpine wetlands in Southwest China, researchers can use this practical approach to estimate multi- temporal areas and storages and reveal the storage- area relationship of open water in the wetlands. The study provided valuable information of this ease wetland for optimizing its hydro-ecological managements and a new method to wetland researchers and managers for the hydrological study of similarly ungauged wetland complex. 展开更多
关键词 Water storage Ungauged wetland Napahai Wetland Normalized Difference WaterIndex
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Changes of hydrochemical composition and heavy metals concentration in shallow groundwater from karst hilly areas in Guiyang region,China 被引量:2
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作者 刘方 刘丛强 +1 位作者 赵杨 李准 《Journal of Central South University》 SCIE EI CAS 2010年第6期1216-1222,共7页
The quality changes of shallow groundwater from karst hilly areas in Guiyang region of China impacted by the urbanization were investigated. The results show that the major ions in shallow groundwater from the karst h... The quality changes of shallow groundwater from karst hilly areas in Guiyang region of China impacted by the urbanization were investigated. The results show that the major ions in shallow groundwater from the karst hilly areas are mainly composed of HCO3^-, SO4^2-, Ca^2+ and Mg^2+, and the concentrations scopes of NO3^-, Cl^-, K^+ and Na^+ of the groundwater in agricultural, residential and industrial areas are 4.5-9.6, 2.8-7.1, 3.9-6.3 and 2.5-4.9 times higher than those in the forest areas, respectively. The concentrations of As, Pb and Cd of shallow groundwater in the industrial areas are also significantly enhanced, followed by those in the residential areas and the agricultural areas. The concentrations of NO3^-, SO4^2- , As, Pb and Cd of the groundwater in the industrial areas and those of NO3^- , SO4^2-, As and Cd of shallow groundwater in the residential areas reach grade Ⅲ of the Groundwater Quality Standard of China (GB/T 14848-93), while the concentration of NO3^- in the groundwater from the industrial areas exceeds grade V. With the process of urbanization, NO3^- is the key factor to influence the groundwater quality in karst hilly areas, followed by SO4^2-, As, Pb and Cd. 展开更多
关键词 karst hilly areas shallow groundwater URBANIZATION heavy metals Guiyang
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Farmer's Adaptive Strategies on Land Competition between Societal Outcomes and Agroecosystem Conservation in the Purple-soiled Hilly Region,Southwestern China 被引量:3
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作者 TANG Qiang BAO Yuhai +2 位作者 HE Xiubin ZHU Bo ZHANG Xinbao 《Journal of Mountain Science》 SCIE CSCD 2012年第1期77-86,共10页
The worldwide extension and intensification of farming during the last century has led to ecosystem degradation and caused a series of environmental problems.Conservation of ecosystem services in agricultural regions ... The worldwide extension and intensification of farming during the last century has led to ecosystem degradation and caused a series of environmental problems.Conservation of ecosystem services in agricultural regions has been implemented by top-down government actions or initiated by resilience scientists in the developed countries,but little attention was paid in the developing countries,especially in some remote mountainous regions.The present paper presents a case study showing how local farmers obtained both maximal societal outcomes and agroecosystem conservation interests in the absence of distinct boundaries between agricultural and protected ecological areas in the densely populated purple-soiled hilly region of southwestern China.The local community(Yanting County) has developed a mosaic agricultural-forestry-fishery-stock breeding system with spatially targeted land uses,diverse agricultural productions and multiple ecological partnerships.It indicates that the local farmers have hereditarily perceived sound strategies on maximizing sustainable societal outcomes and optimizing tradeoffs among macro-market,state policy,new technological facility and ecological reinforcement. 展开更多
关键词 Mosaic agroforestry system Adaptive strategies Land competition Agroecosystem conservation Purple-soiled hilly region China
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Relocation of Earthquakes in the Northeastern Tianshan Mountains Area and Improvement of Local 1-D Crustal Velocity Model 被引量:1
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作者 Sun Anhui Chen Qifu +2 位作者 Chen Yong Li Gang Zhang Zhiqiang 《Earthquake Research in China》 2012年第3期321-334,共14页
We apply three methods to relocate 599 earthquake events that occurred from August 2004 to August 2005 in the northeastern Tianshan Mountains area ( 85°30' ~ 88°30'E,43°00' ~ 44°40... We apply three methods to relocate 599 earthquake events that occurred from August 2004 to August 2005 in the northeastern Tianshan Mountains area ( 85°30' ~ 88°30'E,43°00' ~ 44°40' N ) by using travel times recorded by regional seismic network and 10 portable seismic stations deployed around the Urumqi city. By comparing the reliability of different results,we determined a suitable location method,and an improved 1-D crustal velocity model of the study area. The uncertainty of earthquake location is significantly reduced with combined data of seismic network and portable stations. The relocated events are clearly associated with regional tectonics of the northeastern Tianshan Mountains area, and are also in agreement with the existence of active faults imaged by deep seismic reflection profile. The relocated seismicity discovers some potential traces of buried active faults,which need to be validated further. 展开更多
关键词 Earthquake relocation Velocity model The northeastern Tianshan Mountains area Active faults
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Impact of Land Use Change on Groundwater Recharge in Guishui River Basin,China 被引量:5
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作者 PAN Yun GONG Huili +2 位作者 ZHOU Demin LI Xiaojuan NAKAGOSHI Nobukazu 《Chinese Geographical Science》 SCIE CSCD 2011年第6期734-743,共10页
It is important to understand how land use change impacts groundwater recharge, especially for regions that are undergoing rapid urbanization and there is limited surface water. In this study, the hydrological process... It is important to understand how land use change impacts groundwater recharge, especially for regions that are undergoing rapid urbanization and there is limited surface water. In this study, the hydrological processes and re- charge ability of various land use types in Guishui River Basin, China (in Beijing Municipality) were analyzed. The impact of land use change was investigated based on water balance modeling, WetSpass and GIS. The results indicate that groundwater recharge accounts for only 21.16% of the precipitation, while 72.54% is lost in the form of evapotranspiration. The annual-lumped groundwater recharge rate decreases in the order of cropland, grassland, urban land, and forest. Land use change has resulted in a decrease of 4 x 106 m3 of yearly groundwater recharge in the study area, with a spatially averaged rate of 100.48 mm/yr and 98.41 mm/yr in 1980 and 2005, respectively. This variation has primarily come from an increase of urban area and rural settlements, as well as a decrease of cropland. 展开更多
关键词 groundwater recharge land use change soil water balance hydrological processes
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A Preliminary Study on the New Activity Features of the Lajishan Mountain Fault Zone in Qinghai Province 被引量:3
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作者 Yuan Daoyang Zhang Peizhen +2 位作者 Lei Zhongsheng Liu Baichi Liu Xiaolong 《Earthquake Research in China》 2005年第4期391-401,共11页
The Lajishan Mountain fault zone consists of two NE_protruding arcuate faults, i.e. the northern and southern margin fault of Lajishan Mountain with the fault length of 230km and 220km respectively. The fault zone is ... The Lajishan Mountain fault zone consists of two NE_protruding arcuate faults, i.e. the northern and southern margin fault of Lajishan Mountain with the fault length of 230km and 220km respectively. The fault zone is located in the large_scale compressional structure zone and tectonic gradient zone in_between the NNW_trending right_lateral strike_slip Reshui_Riyueshan fault zone and the NWW_trending left_lateral strike_slip northern margin of west Qinling Ranges fault zone is also an important boundary fault zone, separating the Xining_Minhe basin and the Xunhua_Hualong basin at the southern and northern sides of the Lajishan Mountain respectively. Geologic geomorphic evidences of new activity revealed by field investigations indicate that the latest movement of the Lajishan fault zone was in late Epipleistocene (only a few segments were active in early Holocene) and is mainly of compressive thrusting with slightly left_lateral strike_slip component. The above movement has possibly resulted in the occurrence of about 20 moderate earthquakes of magnitude around 5.0. The Lajishan region can therefore be regarded as a seismotectonic window to reflect tectonic movement and earthquake activity. 展开更多
关键词 Lajishan Mountain Active fault Historical earthquake New activity
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Relatedness of Helicobacter pylori populations to gastric carcinogenesis 被引量:4
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作者 Quan-Jiang Dong Shu-Hui Zhan +3 位作者 Li-Li Wang Yong-Ning Xin Man Jiang Shi-Ying Xuan 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第45期6571-6576,共6页
Helicobacter pylori (H. pylorl) is a Gram-negative bac- terium that infects half of the human population. The infection is associated with chronic inflammation of the gastric mucosa and peptic ulcers. It is also a m... Helicobacter pylori (H. pylorl) is a Gram-negative bac- terium that infects half of the human population. The infection is associated with chronic inflammation of the gastric mucosa and peptic ulcers. It is also a major risk factor for gastric cancer. Phylogenetic analysis of global strains reveals there are seven populations of H. pylori, including hpAfrical, hpAfrica2, hpEastAsia, hpEurope, hpNEAfrica, hpAsia2 and hpSahul. These populations are consistent with their geographical origins, and pos- sibly result from geographical separation of the bac- terium leading to reduced bacterial recombination in some populations. For each population, H. pylori has evolved to possess genomic contents distinguishable from others. The hpEurope population is distinct in that it has the largest genome of 1.65 mbp on average, and the highest number of coding sequences. This confers its competitive advantage over other populations but at the cost of a lower infection rate. The large genomic size could be a cause of the frequent occurrence of the deletion of the cag pathogenicity island in H. pylori strains from hpEurope. The incidence of gastric cancer varies among different geographical regions. This can be attributed in part to different rates of infection of H. pylori. Recent studies found that different popula- tions of H, pylori vary in their carcinogenic potential and contribute to the variation in incidence of gastric cancer among geographical regions. This could be related to the ancestral origin of H, pylori. Further studies are indi- cated to investigate the bacterial factors contributing to differential virulence and their influence on the clinical features in infected individuals. 展开更多
关键词 Helicobacter pylori Population genetics Gastric cancer VIRULENCE GENOME
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