地泊坦胶囊

【作用特点】本品以活性成分5-氨基水杨酸替代柳氮磺吡啶中无活性的磺胺吡啶,即通过偶氮连接两分子5-氨基水杨酸,提高了疗效,降低了不良反应发生率。5-氨基水杨酸是治疗溃疡性结肠炎的有效成分,它作用于炎症粘膜,可抑制引起炎症的前列腺素合成,抑制增强细胞膜通透性而引起水肿的炎症介质白三烯的形成。但口服5-氨基水杨酸在小肠中被吸收,乙酰化后随尿排出,不能达到结肠部位。而本品在胃和小肠不能吸收也不分解,其偶氮桥到达结肠后才被结肠内细菌分裂为二分子有效的5-氨基水杨酸显示其抗炎作用。且5-氨基水杨酸局部结肠浓度大于血清中药浓度的1000倍。

Landscape Pattern Evolution Processes of Alpine Wetlands and Their Driving Factors in the Zoige Plateau of China

Zoige Plateau wetlands are located in the northeastern corner of the Qinghai-Tibet Plateau.The landscape pattern evolution processes in the Zoige Plateau and their driving factors were identified by analyzing the dynamic changes in landscape modification and conversion and their dynamic rates of alpine wetlands over the past four decades.The results showed that the landscape conversion between wetlands and non-wetlands mainly occurred during the period from 1966 to 1986.The marsh wetland area converted from lake and river wetlands was larger because of swamping compared to other wetland landscapes.Meanwhile,the larger area of marsh wetlands was also converted to lake wetlands more than other types of wetlands.The modification processes mainly occurred among natural wetland landscapes in the first three periods.Obvious conversions were observed between wetland and nonwetland landscapes(i.e.,forestland,grassland,and other landscapes) in the Zoige Plateau.These natural wetland landscapes such as river,lake and marsh wetlands showed a net loss over the past four decades,whereas artificial wetland landscapes(i.e.,paddy field and reservoir and pond wetlands) showed a net decrease.The annual dynamic rate of the whole wetland landscape was 0.72%,in which the annual dynamic rate of river wetlands was the highest,followed by lake wetlands,while marsh wetlands had the lowest dynamic rate.The integrated landscape dynamic rate showed a decreasing trend in the first three periods.The changes in wetland landscape patterns were comprehensively controlled by natural factors and human activities,especially human activities play an important role in changing wetland landscape patterns.

Ecology of macrozoobenthic communities in two plateau lakes of Southwest China

Ecological studies on macrozoobenthos were conducted in two small plateau lakes in the Yunnan-Guizhou Plateau, Southwest China： Xingyun Lake （XL）, a eutrophic lake whose main source of primary production was phytoplankton （Chl α=99.76±24.01 μg/L）, and Yangzong Lake （YL）, a mesotrophic lake. Sampling was carried out from October 2002 to May 2004. Altogether 23 benthic taxa were identified in XL and 21 taxa in YL. The density of benthos in XL was much lower than that in YL, but the biomass was about equal in the two lakes, being I 423 ind/m^2 and 8.71 g/m^2 in XL and 4 249 ind/m^2 and 8.60 g/m^2 in YL. The dominant species were Limnodrilus hoffmeisteri, Branchiura sowerbyi, Aulodrilus pluriseta and Chironomus sp. in XL and Limnodrilus hoffrneisteri, Aulodrilus pluriseta and Bellamya sp. in YL. Seasonal fluctuation occurred, showing richer species in summer and winter, but the density and biomass varied in different ways in the two lakes. Analyses on functional feeding groups indicate that collector-gatherers were predominant, but the relative abundances of other groups were different. Stepwise multiple regression analysis demonstrated that the water depth, conductivity and chlorophyll a were the key factors affecting macrozoobenthic abundance in the lakes.

Mapping of Freshwater Lake Wetlands Using Object-Relations and Rule-based Inference

Inland freshwater lake wetlands play an important role in regional ecological balance. Hongze Lake is the fourth biggest freshwater lake in China. In the past three decades, there has been significant loss of freshwater wet- lands within the lake and at the mouths of neighboring rivers, due to disturbance, primarily from human activities. The main purpose of this paper was to explore a practical technology for differentiating wetlands effectively from upland types in close proximity to them. In the paper, an integrated method, which combined per-pixel and per-field classifi- cation, was used for mapping wetlands of Hongze Lake and their neighboring upland types. Firstly, Landsat ETM＋ imagery was segmented and classified by using spectral and textural features. Secondly, ETM＋ spectral bands, textural features derived from ETM＋ Pan imagery, relative relations between neighboring classes, shape fea^xes, and elevation were used in a decision tree classification. Thirdly, per-pixel classification results from the decision tree classifier were improved by using classification results from object-oriented classification as a context. The results show that the technology has not only overcome the salt-and-pepper effect commonly observed in the past studies, but also has im- proved the accuracy of identification by nearly 5%.

Review of studies on land use and land cover change in Nepal

Land use and land cover(LULC) in Nepal has undergone constant change over the past few decades due to major changes caused by anthropogenic and natural factors and their impacts on the national and regional environment and climate.This comprehensive review of past and present studies of land use and land cover change(LUCC) in Nepal concentrates on cropland, grassland, forest, snow/glacier cover and urban areas. While most small area studies have gathered data from different sources and research over a short period, across large areas most historical studies have been based on aerial photographs such as the Land Resource Mapping Project in 1986. The recent trend in studies in Nepal is to focus on new concepts and techniques to analyze LULC status on the basis of satellite imagery, with the help of geographic information system and remote sensing tools. Studies based on historical documents, and historical and recent spatial data on LULC, have clearly shown an increase in cropland areas in Nepal,and present results indicating different rates and magnitudes. A decrease in forest and snow/glacier coverage is reported in most studies. Little information is available on grassland and urban areas from past research. The unprecedented rate of urbanization in Nepal has led to significant urban land changes over the past 30 years. Meanwhile, long term historical LUCC research in Nepal is required for extensive work on spatially explicit reconstructions on the basis of historical and primary data collection, including LULC archives and drivers for future change.

Shrinking and Drying up of Baiyangdian Lake Wetland:A Natural or Human Cause?

The shrinking and drying up of wetlands in arid and semiarid areas of China have been widely observed in the recent years, but there has been no consensus on whether the aggravation is caused by human activities or by global climate warming. For a better understanding of the cause, this study investigates the dynamic changes of Baiyangdian Lake wetland over the last 40 years. It is shown that since the 1980s, Baiyangdian Lake has suffered from an insufficient water input and shrunk considerably. By using SPSS 11.0, this study urines a detailed Analysis on the signifficance of the effects of the possible driving factors for the degradation. It is identified that the North China Plain has been warrnin~ up significantly in recent years, which causes a significant reduction in the precipitation and inflow to the lake. Although human disturbances such as the irrigation and storage of water in reservoirs do not play a decisive role, they accelerate the degradation and their effects should be minimized.

Monitoring Glacier and Supra-glacier Lakes from Space in Mt. Qomolangma Region of the Himalayas on the Tibetan Plateau in China

Because of the large number and remoteness, satellite data, including microwave data and optical imagery, have commonly been used in alpine glaciers surveys. Using remote sensing and Geographical Information System （GIS） techniques, the paper presents the results of a multitemporal satellite glacier extent mapping and glacier changes by glacier sizes in the Mt. Qomolangma region at the northern slopes of the middle Himalayas over the Tibetan Plateau. Glaciers in this region have both retreated and advanced in the past 35 years, with retreat dominating. The glacier retreat area was 3.23 km2 （or o.75 km^2 yr^-1 during 1974 and 1976, 8.68 km^2 （or 0.36 km^2 yr^-1 during 1976 and 1992, 1.44 km^2 （or 0.12 km^2 yr^-1） during 1992-2ooo. 1.14 km^2 （or 0.22 km^2 yr^-1 during 2000-2003, and 0.52 km^2 （or 0.07 km^2 yr^-1 during 2003-2008, respectively. While supra-glacier lakes on the debris-terminus of the Rongbuk Glacier were enlarged dramatically at the same time, from 0.05 km^2 in 1974 increased to 0.71 km^2 in 2008, which was more than 13 times larger in the last 35 years. In addition, glacier changes also showed spatial differences, for example, glacier retreat rate was the fastest at glacier termini between 5400 and 5700 m a.s.l than at other elevations. The result also shows that glaciers in the middle Himalayas retreat almost at a same pace with those in the western Himalayas.

A large Middle Pleistocene freshwater to oligohaline lake in the contemporary hyperarid Qaidam Basin （China）

The Qaidam Basin （NW China） at the northern margin of the Tibetan Plateau is one of the driest places on Earth with mean annual precipitation not exceeding 25 mm in the western central part. Flat salt plains and wind-shaped hills characterise the bare ground over thousands of square kilometres. In contrast to presentday conditions, remnants of ancient shorelines in high positions identified by Chen and Bowler （1986） and HiJvermann and Siissenberger （1986） about 20 years ago herald of a former large lake but were not investigated further till now. Here we present the results of microfossil analysis and optically stimulated luminescence （OSL） as well as uranium-series （TIMS） dating of sediments from a thick sequence of predominantly lake deposits in the eastern central Qaidam Basin. Based on abundant ostracod （micro-crustacean） shells from this sequence, we infer that a large lake of several metres depth at least maintained primarily fresh to oligohaline conditions in the late Middle Pleistocene.

PALEOCLIMATIC CHANGES IN DABUSU LAKE

Study on the carbonate content and oxygen isotope of a sediment section in Dabusu Lake revealed that this region has experienced several cold wet and warm dry climatic cycles since 15400 a BP. It was about 6740 a BP when the climate in the region reached a relatively stable warm stage, so that the lake water was gradually condensed and finally a saline lake was formed.

Temporal changes in wetland plant communities with decades of cumulative water pollution in two plateau lakes in China's Yunnan Province

Abstract： Wetland plant communities in the plateau lakes of Yunnan Province, China, have decreased significantly over the past decades. To better understand this degradation, we analyzed the processes and characteristics of changes in wetland plant communities in two of the largest lakes in Yunnan Province, Dianchi and Erhai lakes. We collected records of native and alien plant communities in the two lakes from literature published from the 195os to current period. We calculated plant community types and their area in some historical periods when related data were reported, and analyzed the relationship between chances in nlant communities and water nollution. InDianehi Lake, 12 community types of native plant communities, covering over 80% of the surface in the 195os and 196os, were reduced to four types covering 2.4% by the late 2ooos. Alien plant communities started to appear in the lake in the late 197os, and have since come to cover 4.9% of the lake surface, thereby becoming dominant. In Erhai Lake, 16 community types of native plant communities, covering 47.1% of the lake surface in the late 197os, declined to lo community types, covering 9.3% of the surface, by the late 2ooos. Alien plant communities appeared in the middle 198os, and at present cover 0.7% of the surface area. It was indicated that changes in plant communities were significant related to water eutrophication. The area occupied by native and alien plant communities was, respectively, negatively andpositively related to the content of nutrients in water. This showed lacustrine pollution played an important role in native plant loss and alien plant invasion in the two plateau lakes.

A singular spectrum analysis on Holocene climatic oscillation from lake sedimentary record in Minqin Basin, China

The total organic carbon (TOC) content series from the lake sediment of Minqin Basin (100°57′–104°57′E, 37°48′–39°17′N) in northwestern China, which has a 10 000-year-long paleo-climatic proxy record, was used to analyze the Holocene climate changes in the local region. The proxy record was established in the Sanjiaocheng (SJC), Triangle Town in Chinese, Section (103°20′25″E, 39°00′38″N), which is located at the northwestern boundary of the present Asian summer monsoon in China, and is sensitive to global environmental and climate changes. Applying singular spectrum analysis (SSA) to the TOC series, principal climatic oscillations and periodical changes were studied. The results reveal 3 major patterns of climate change regulated by reconstructed components (RCs). The first pattern is natural long-term trend of climatic change in the local area (Minqin Basin), indicating a relatively wetter stage in early Holocene (starting at 9.5 kaBP), and a relatively dryer stage with a strong lake desiccation and a declined vegetation cover in mid-Holocene (during 7–6 kaBP). From 4.0 kaBP to the present, there has been a gradually decreasing trend in the third reconstructed component (RC3) showing that the local climate changed again into a dryer stage. The second pattern shows millennial-centennial scale oscillations containing cycles of 1 600 and 800 years that have been present throughout almost the entire Holocene period of the last 10 000 years. The third pattern is a millennial-centennial scale variation with a relatively smaller amplitude and unclear cycles showing a nonlinear interaction within the earth’s climate systems.

Desertification and Blown Sand Disaster in China

Approximately 331 million ha, one-third of China＇s total land, is prone to desertification processes, leading to natural disasters and economic losses. In this study, the situation, tendency, their influences and their risk governance of desertification and blown sand disaster in China were examined using satellite images, field photographs, field data and a literature review. The desiccated areas in Lop Nor and the lower Heihe River fluvial plain covered about 50,000 km2 and 40,000 km2, respectively. In Ejina, about 100 species of vegetation became extinct. The rate of wind erosion in China was between 1,000 tons/km2/year and 2,000 tons/km2/year. There were 12 sand deserts and sandy lands, occupying a total of 710,000 km2. Salinized soils occurred across 99.1 million ha. The two main sand and dust storm-prone areas in China were the Tarim Basin and its surroundings, and the Alxa Plateau and its surroundings. From 1981 to 2007, the annual average frequency of sand and dust storms varied from 1 d to 37 d with a general increase from southeast to northwest. Since 1978, China has implemented a number of ecological construction projects that have reduced desertification from 1999 to 2004 and from 2005 to 2009, and the number of dust and sand storm days from 9.3 d between 1954 and 1959 to 4.4 d between 2000 and 2007. The results could improve understanding of desertification and blown sand disasters in China and provide valuable experiences for global desertification control.

Valuation of Lake and Marsh Wetlands Ecosystem Services in China

Wetlands are highly productive natural ecosystems, providing valuable goods and services. There is growing interest in transferring ecosystem service value from the existing wetlands studied to other wetlands ecosystems at a large geographic scale. The benefit transfer method uses the known values from wetlands to predict the value of other wetland sites. This methodology requires only limited time and resources. The present study calculated the value of the ecological services provided by lake and marsh wetlands in China in terms of biodiversity indices, water quality indices and economic indices. Basic data on wetlands were obtained through remote sensing images. The results show that: 1) The total ecosystem service value of the lake and marsh wetlands in 2008 was calculated to be 8.1841 × 1010 United States Dollars(USD), with the marsh and lake wetlands contributing 5.6329 × 1010 and 2.5512 × 1010 USD, respectively. Values of marsh ecosystem service were concentrated in Heilongjiang Province(2.5516 × 1010 USD), Qinghai Province(1.2014 × 1010 USD), and Inner Mongolia Autonomous Region(1.1884 × 1010 USD). The value of the lakes were concentrated in Tibet Autonomous Region(6.223 × 109 USD), Heilongjiang(5.810 × 109 USD), and Qinghai(5.500 × 109 USD). 2) Waste treatment and climate regulation services contributed to 26.29% and 24.74% respectively, of the total ecosystem service value of the marsh wetlands. Hydrological regulation and waste treatment contributed to 41.39% and 32.75%, respectively, of the total ecosystem service value of the lake wetlands. 3) The total ecological service value of the lake and marsh wetlands was 54.64% of the total service value of natural grassland ecosystems and 30.34% of the total service value of forests ecosystems in China.

Reproduction of the Sedimentary Disturbance Phenomenon of the Diexi Ancient Landslide-Dammed Lake under Earthquake

Valuable geological and environmental information can be obtained from the 200 m thick lacustrine sediments in the Diexi lake(an ancient landslide-dammed lake) of the Minjiang River. The shaking table test method was employed to study the disturbance phenomena which occurred in the Diexi lake sediments. The results show that the disturbance phenomena were caused by liquefaction-induced flows in the unconsolidated lacustrine sediments, due to triggering by earthquakes. The deformations only occurred in unconsolidated sediment layers and not in consolidated layers. This means that a consolidated layer cannot be liquefied and disturbed again by an earthquake for a second time. The disturbance on one layer corresponds to only one earthquake. The temporal occurrence of earthquakes could be determined by disturbance layers generated at different ages. In total, 10 disturbed layers were found in the lacustrine sediments of the Diexi lake. The experiments showed that there were more than 10 earthquakes between 30 ka B.P. and 15 ka B.P. in the Diexi lake area based on the dating of the disturbed sediment layers.

Analysis and Study on the Change of the Observed Geo-electric Field Data at Lhasa Geomagnetic Station before and after the Nepal MS8.1 Earthquake

In this paper,the main purpose is to analyze and research the characteristics of the geoelectric field observed data with a long time span and large amplitude abnormal change,at the Lhasa geomagnetic station( hereafter referred to as "Lhasa station "),before and after the Nepal M_S8. 1 strong earthquake,which occurred on April 25,2015. Based on the observation conditions,the observation system,and the observed data of Lhasa station preliminary discussed,the main characteristics of the abnormal change and evolution process are analyzed and studied,using the following two methods; the "synthesis energy accumulation"and the "power as MSA spectrum"analysis,from the two aspects of the"Time Domain"and"Frequency Domain. "The results show that the abnormal change of the geo-electric field observation of Lhasa station experienced a development stage following the process of "trend change- disturbance change- earthquake period-recovery period",and an evolution process of "low frequency change- high frequency change- smooth change- high frequency change ",before and after the Nepal M_S8. 1strong earthquake. Comprehensive analysis shows that the variation characteristics and evolution process of the geo-electric field at Lhasa station are basically consistent with the results of the relevant mechanism and phenomenon research. So far,this is valuable information with certain objectivity,which is typical and representative to reflect the whole process of the gestation, occurrence and complete development of such strongearthquakes.

Experiences with Constructed Wetland Systems in Korea

In spite of the low temperature during the winter season and the high land environment, the wetland treatment system is gaining popularity in Korea because of its lower construction cost and simplicity in operation and maintenance. Many different types of wetland treatment systems have been built during the last 10 years, among which the free water surface wetland has been predominant. Most of the large-scale systems are government projects for improving the water quality of the streams flowing into the estuary dikes and reservoirs. The covering plants used in this system are different in different areas but cattails and reeds or their combinations are common. Constructed wetlands in Korea can be characterized by their shallow depths and short hydraulic residence times. There is no established flow pattern and configuration rules for constructing wetlands, but many efforts have been made with a view to improving their ecological function. Flow control is the most difficult problem in designing a riverbed or riparian wetland. There have been scores of flow rate control devices developed for wetlands, but none of them guarantee wetlands’ safety against flooding. In earlier wetland construction, the building materials were mainly soil. Recently, strong and durable building materials such as rocks, gravel beds, concrete and steel are used at vulnerable places to protect them from erosion. Our investigation indicated that the wetland system would be an appropriate technology because it is not only cheaper to construct, but also requires less maintenance work. However, we suffer from the reduced effectiveness in performance during the winter. We need to evaluate the partial treatment accomplished during 6 to 7 months per year.

Boron isotope geochemistry of Zigetang Co saline lake sediments,Tibetan Plateau

The origin of boron in boron-rich salt lakes in the Tibetan Plateau is highly controversial.In this study,we carried out a detailed study on boron geochemistry and isotope composition of lake sediments collected in Zigetang Co,central Tibet.Evaporites had high boron concentrations of 172.3–418.6 lg/g and δ^(11)B values of-8.2%to-3.3%,suggesting a non-marine origin for the saline lake.The boron isotopic fractionation factor,a,between evaporite and brackish water(a_(evaporite–brackish))decreased systematically with depth,from 0.9942 at the top of the drill core to 0.9893 at the bottom;the linear variation between α_(evaporite–brackish)and depth reflects boron isotopic fractionation associated with progressive crystallization.The positive correlation between δ^(11)B versus[B]and δ^(11)B versus depth in the evaporite phase reflects pH and boron speciation in the solution control on the adsorption of boron,and B(OH)_3 species incorporated preferentially into Mg(OH)_2 precipitation at high pH.

Micro-site Conditions of Epiphytic Orchids in a Human Impact Gradient in Kathmandu Valley, Nepal

We studied distribution and site conditions of epiphytic orchids in a gradient of human interference in Kathmandu valley, central Nepal. The aim was to understand the recent distribution pattern of epiphytic orchids, with respect to (i) the micro-site conditions and (ii) the type and intensity of land use. The occurrence of epiphytic orchids was recorded for a grid with 1.5 km cell size. The cells represent different types and intensities of human impact. Site factors such as bark rugosity, bark pH, diameter at breast height (dbh; 1.3 m) of host trees, exposure to wind and sunlight intensity were recorded. With regard to the species richness and abundance of epiphytic orchids, we compared different human impact categories from very strong human impact (settlement area) to very low human impact (national park). Remote sensing was used for a supervised classification of land cover. Ficus religiosa turned out to be the most important host species for orchids in urban areas, while Schima wallichii and Alnus nepalensis significantly host orchids in the other categories. Both species richness and abundance of epiphytic orchids were significantly higher under very low human impact (forest in national park) and also some remaining patches of primary forest than the other regions. Micro-climate is crucial for orchid populations. Host bark pH, bark rugosity, sunlight intensity and host exposure were significantly different for all human impact categories in order to harbour epiphytic orchid species. Habitats with a mixture of mature trees are suitable and essential for the conservation of viable populations of epiphytic orchids in settled areas. The study reveals that to improve the population size of orchids it is essential for future urban forestry to: (i) Protect old trees as carriers of existing epiphytic orchid diversity, (ii) protect medium old trees to ensure that they may become old trees, (iii) plant new host trees for the future, (iv) plant in groups instead of single isolate trees. Trees should especially be planted in areas where orchids still exist to provide more trees for orchid population enlargement (e.g. along riparian system). Native species should be favoured; the pool of such native host species is wide.

Study of Crustal Thickness and Poisson Ratio of Hebei and Its Adjacent Areas by Teleseismic Receiver Function

We collected waveforms of a teleseismic event which occurred from January 2007 to October 2011 from 174 broadband seismic stations deployed in Hebei and its adjacent areas. Using the H-k stacking method,the average thickness and Poisson's ratio of the crust are acquired. In order to obtain reliable receiver functions, the broadband seismograms of 488 teleseismic earthquakes occurring in the epicentral distance range from 30° to 90° with magnitudes larger than Mb6. 0 are collected. The results show that crustal thickness have conspicuous lateral heterogeneity and have good correlation to the regional geological tectonic features. Poisson ratio's value is equated with the global models estimates which fluctuate at about 0. 25. Crustal thickness has positive correlation to the topography and the Taihang Mountains form the transition zone of thick and thin crustal thickness. There is an obvious difference in crustal thickness beneath the north and south of the Shanxi earthquake zone and the Poisson ratio of Datong,Ningwu and Anze basins is greater than 0. 3. The crustal thickness beneath the Zhang-Bo( Zhangjiakou-Bohai Sea)earthquake zone decreases from west to north and its Poisson ratio shows conspicuous lateral heterogeneity. The thin crust and low Poisson ratio in the Huabei( North China)basin may correlate with the delamination of the North China craton.

The dynamic analysis of natural environment change of nuclear test field in Lop Nur region of China

Using earth satellite observation means, remote sensing information distilled technique and regional research production, we have roundly analyzed and made an integrated evaluation about the Lop Nur nuclear test field in western China. This product reveals the rarely-known nuke explosion effect and response events of geology conditions. It also offers us legible and practical first-hand materials about human extreme effects, important engineering environment and intimidating influence process. By excavating and appraising the materials gradually on the natural environment factors changing in the test field through macroscopic elimination and typical filtration, it can supply basic scientific data for security of national nuclear usage, appraising the nuclear environment synthetically and developing nuclear strategy expediently.