经历唐山地震应激的胎儿及婴儿成年后的尿酸水平

目的探讨胎儿期及婴儿期经历地震应激对成年期血尿酸水平的影响。方法本研究的受试者来自开滦矿业集团和石家庄钢铁厂职工，共纳入996人。根据暴露于地震情况分为胎儿期地震暴露组（326人）、婴儿期地震暴露组（307人）以及对照组（333人），对照组为同时期出生于石家庄市，未经历地震的人群。根据暴露的妊娠时期不同，胎儿期地震暴露组又分为3个亚组，1～3个月胎儿暴露组，4。6个月胎儿暴露组，7—9个月胎儿暴露组。比较3组之间尿酸水平、高尿酸血症的发生率。比较高尿酸血症组与非高尿酸血症组的一般基线资料。同时以是否高尿酸血症为因变量，以性别、体质指数（BMI）、吸烟、饮酒、高血压病、糖尿病、受教育程度、婚姻状况、高密度脂蛋白胆固醇（HDL—C）、低密度脂蛋白胆固醇（LDL—C）、甘油三酯（TG）、总胆固醇（TC）为自变量进行Logistic回归分析。结果与对照组相比，胎儿期与婴儿期地震暴露组尿酸水平均升高，组间比较差异有统计学意义（F=15．810，P〈0．01）；3组间高尿酸血症发生率比较差异有统计学意义（χ2=20．628，P〈0．01），胎儿期与婴儿期地震暴露组高尿酸血症发生率均高于对照组，并且胎儿期高于婴儿期地震暴露组；胎儿期地震暴露组各亚组间尿酸水平、高尿酸血症发生率比较差异无统计学意义（P〉0．05）；回归分析结果表明胎儿期（OR=2．895，95％CI=1．652～5．075）、婴儿期（OR=1．882，95％CI=1．044—3．394）经历地震应激是导致高尿酸血症的危险因素。结论早年经历地震应激是成年期高尿酸水平及高尿酸血症发生率升高的危险因素之一，尤其在胎儿期经历地震应激人群校为突出。

利用SCI-E对地震创伤后应激障碍文献的分析

为了解国内外对地震创伤后应激障碍的研究状况,利用SCI-E数据库检索地震创伤后应激障碍相关文献,并对检出文献进行作者、国家、文献类型、机构、语种、出版年、期刊等方面分析。发现相关研究文献主要是由美国、日本、台湾等国家和地区学者用英文发表的一次文献,且呈增长趋势。指出我国应重视汶川地震后的心理疗伤工作,充分吸收国外的经验,尽早开展心理干预工作。

EARTHQUAKE RESPONSE OF SEMI RIGID FRAME WITH ROTATIONAL DAMPER

The seismic behavior of frames with semi rigid connections and rotational dampers is examined.The ground acceleration due to earthquake is regarded as a stochastic process,and a pseudo excitation algorithm in frequency domain is implemented in a computer program to handle non orthogonal damping properties of the system.The computer program which incorporates detailed connection models and rotational damping models is used to investigate the effect of the connection of the semi rigid frame.It is shown from analytical studies that semi rigid frames with rotational dampers improve the seismic response of the building and may provide an effective and reliable earthquake resistant design solution.

Nonlinear analysis of pounding between decks of multi-span bridge subjected to multi-support and multi-dimensional earthquake excitation

The nonlinear analysis of pounding between bridge deck segments subjected to multi-support excitations and multi-dimensional earthquake motion was performed.A novel bottom rigid element(BRE)method of the current displacement input model for structural seismic analysis under the multi-support excitations was used to calculate structural dynamic response.In the analysis,pounding between adjacent deck segments was considered.The seismic response of a multi-span bridge subjected to the multi-support excitation,considering not only the traveling-wave effect and partial coherence effect,but also the seismic non-stationary characteristics of multi-support earthquake motion,was simulated using finite element method(FEM).Meanwhile,the seismic response of the bridge under uniform earthquake was also analyzed.Finally,comparative analysis was conducted and some calculation results were shown for pounding effect,under multi-dimensional and multi-support earthquake motion,when performing seismic response analysis of multi-span bridge.Compared with the case of uniform/multi-support/multi-support and multi-dimensional earthquake input,the maximum values of pounding force in the case of multi-support and multi-dimensional earthquake input increase by about 5 8 times;the absolute value of bottom moment and shear force of piers increase by about50%600%and 23.1%900%,respectively.A conclusion can be given that it is very necessary to consider the pounding effect under multi-dimensional and multi-support earthquake motion while performing seismic response analysis of multi-span bridge.

Semi-active predictive control strategy for seismically excited structures using MRF-04K dampers

The theoretical study of a semi-active predictive control(SAPC) system with magnetorheological(MR) dampers to reduce the responses of seismically excited structures was presented.The SAPC scheme is based on a prediction model of the system response to obtain the control actions by minimizing an object function,which has a function of self-compensation for time delay occurring in real application.A double-ended shear mode combined with a valve mode MR damper,named MRF-04K damper,with the maximum force of 20 kN was designed and manufactured,and parameters of the Bouc-Wen hysteresis model were determined to portray the behavior of this damper.As an example,a 5-story building frame equipped with 2 MRF-04K dampers was presented to demonstrate the performance of the proposed SAPC scheme for addressing time delay and reducing the structural responses under different earthquakes.Comparison with the uncontrolled structure,the passive-off and passive-on cases indicates that both the peak and the norm values of structural responses are all clearly reduced,and the SAPC scheme has a better performance than the two passive cases.

早年应激对唐山矿业人群血脂影响的调查

目的调查胎儿及婴儿期经历应激的个体成年后血脂异常患病情况,并分析其影响因素。方法本研究为横断面研究,共收集1260例开滦矿业集团职工的人口学特征,根据出生日期分为婴儿期地震暴露组372例,胎儿期地震暴露组382例,未暴露组506例,评估空腹血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)指标的差异。结果婴儿期地震暴露组高胆固醇血症、混合型高脂血症患病率高于胎儿期地震暴露组(18.8%比11.3%、13.4%比6.8%,P<0.05);婴儿期地震暴露组血脂异常高于未暴露组(40.0%比27.7%,P<0.05)。单因素分析显示饮酒、体质指数(BMI)、地震应激分组是血脂异常的相关因素(χ2=4.432、6.612、7.690,P<0.05)。非条件Logistic回归分析结果显示,饮酒的血脂异常患病风险是不饮酒者的1.590倍(95%CI=1.102~2.294),婴儿期地震暴露组血脂异常患病风险是未暴露组的1.723倍(95%CI=1.147~2.589),BMI消瘦型较超重/肥胖型对血脂是一个保护性因素(OR=0.280,95%CI=0.080~0.972)。结论婴儿期应激暴露组高胆固醇血症、混合型高脂血症、血脂异常患病率较高,BMI消瘦型是血脂的保护因素,饮酒、婴儿期应激暴露是血脂异常的危险因素。

Clinical Study on Treatment of the Earthquake-caused Post-traumatic Stress Disorder by Cognitive-behavior Therapy and Acupoint Stimulation

Objective： To study the curative effect of acupoint stimulation on the earthquake-caused post-traumatic stress disorder （PTSD）. Methods： The 91 PTSD patients in Wenchuan hit by a strong earthquake were randomly divided into a control group of 24 cases treated by the cognitive-behavior therapy, and a treatment group of 67 cases treated by both cognitive-behavior therapy and acupoint stimulation. The scores were evaluated according to Chinese version of the incident effect scale revised （IES-R） and the self-compiled questionnaire for the major post-traumatic psychological condition, and the curative effect was compared between the two groups. Results： The total scores of IES-R, the scores of all factors and the total scores of the questionnaire in the two groups after treatment were much lower than those before treatment （P〈0.01）. The comparison of reduction in the factor scores between the two groups showed that the curative effect inthe treatment group was better that of in the control group. Conclusion： The acupoint stimulation is effective for the PTSD patients, with better results than that of cognitive-behavior therapy used alone