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α-腈基阿魏酸基体在MALDI-TOFMS测定中的应用研究 被引量:2
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作者 邓慧敏 查庆民 +3 位作者 黎军 邵伟艳 赖志辉 赵善楷 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2001年第7期1102-1104,共3页
This paper reports for the first time an experiment designed in which synthesized α cyano ferulic acid used as a new matrix for the analysis of cytochrome c, trypsin, bovine serum albumin, β cyclodextrin, dextrans a... This paper reports for the first time an experiment designed in which synthesized α cyano ferulic acid used as a new matrix for the analysis of cytochrome c, trypsin, bovine serum albumin, β cyclodextrin, dextrans and DNA d(T) 18 . The results demonstrated that α cyano ferulic acid used as a new matrix could effectively desorb and ionize different kinds of samples, such as proteins and peptides, oligosaccharides, polysaccharides and oligonucleotides. In analysis of dextrans the new matrix gave better results when comparing with the normally used DHB. In analysis of DNA d(T) 18 , the sample could be desorbed and ionized more efficiently even without sample purification, which is normally needed when using 3 HPA as a matrix. 展开更多
关键词 α-腈基阿魏酸 基体 基体辅助光解吸 电离飞行时间质谱 质谱分析
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