Objective: Deep small basal ganglia infarction (DSBI) cannot be clearly classified as either lacune or striatocapsular infarction by their sizes only. We tried to elucidate clinical and other properties of DSBI to und...Objective: Deep small basal ganglia infarction (DSBI) cannot be clearly classified as either lacune or striatocapsular infarction by their sizes only. We tried to elucidate clinical and other properties of DSBI to understand better in pathophysiology of ischemic lesion of basal ganglia. Methods: We analyzed 36 patien ts with acute ischemic lesion of basal ganglia with the size varying from 1.5 to 3 cm in maximal diameters. We assessed clinical features, laboratory data, risk factors of stroke, and radiologic findings such as MRI and MR angiography. Resu lts: Patients with DSBI could be largely divided into two distinctive groups, sm all infarction with cortical sign (SICS) and lacunar syndrome (LS) according to their presence of cortical manifestations. Total of 11 patients were in SICS gro up and they showed cortical manifestations such as eyeball deviation, visual fie ld defect, aphasia and neglect. They also showed severer noncortical neurologic deficit compared with LS group. Whereas LS group showed various MRA patterns, 7 patients of SICS group (63.6%) showed proximal MCA stenosis in MRA. Conclusions : We found that many patients with DSBI could have the features of either lacune or striatocapsular infarction. Although they have similar morphologic character istics but they are presumed to have different pathophysiologic mechanism.展开更多
目的探讨重复经颅磁刺激对基底节区脑梗死后执行功能障碍患者姿势控制能力的改善效果。方法选取2021年9月至2022年12月首都医科大学附属北京天坛医院收治的60例基底节区脑梗死后执行功能障碍患者为研究对象,采用随机数字表法分为试验组...目的探讨重复经颅磁刺激对基底节区脑梗死后执行功能障碍患者姿势控制能力的改善效果。方法选取2021年9月至2022年12月首都医科大学附属北京天坛医院收治的60例基底节区脑梗死后执行功能障碍患者为研究对象,采用随机数字表法分为试验组和对照组,每组30例。对照组给予常规康复治疗,试验组在对照组的基础上联合重复经颅磁刺激治疗。比较分析两组患者治疗前后的执行功能[斯特鲁普色词测试(Stroop color-word test,SCWT)耗时数、SCWT干扰量耗时数],姿势控制能力[10米步行测试(10-meter walking test,10MWT)、起立-行走计时测试(timed up and go test,TUGT)、Berg平衡量表(Berg balance scale,BBS)评分]以及步态参数(步长、步宽、前后位置和左右对称位置)。结果治疗2周后,试验组患者的SWCT耗时数和SWCT干扰量耗时数均显著短于治疗前(P<0.05),且试验组显著短于对照组(P<0.05)。治疗前后,两组患者的10MWT、步长、步宽和前后位置比较差异均无显著性(P>0.05)。治疗2周后,两组患者的BBS评分均显著高于治疗前(P<0.05),且试验组显著高于对照组(P<0.05);试验组患者的TUGT显著优于治疗前(P<0.05),而两组患者的TUGT比较差异无显著性(P>0.05);两组患者的左右对称位置均显著小于治疗前(P<0.05),且试验组显著小于对照组(P<0.05)。结论重复经颅磁刺激可改善基底节区脑梗死患者的执行功能障碍,同时可提高姿势控制能力,改善步态对称性。展开更多
文摘Objective: Deep small basal ganglia infarction (DSBI) cannot be clearly classified as either lacune or striatocapsular infarction by their sizes only. We tried to elucidate clinical and other properties of DSBI to understand better in pathophysiology of ischemic lesion of basal ganglia. Methods: We analyzed 36 patien ts with acute ischemic lesion of basal ganglia with the size varying from 1.5 to 3 cm in maximal diameters. We assessed clinical features, laboratory data, risk factors of stroke, and radiologic findings such as MRI and MR angiography. Resu lts: Patients with DSBI could be largely divided into two distinctive groups, sm all infarction with cortical sign (SICS) and lacunar syndrome (LS) according to their presence of cortical manifestations. Total of 11 patients were in SICS gro up and they showed cortical manifestations such as eyeball deviation, visual fie ld defect, aphasia and neglect. They also showed severer noncortical neurologic deficit compared with LS group. Whereas LS group showed various MRA patterns, 7 patients of SICS group (63.6%) showed proximal MCA stenosis in MRA. Conclusions : We found that many patients with DSBI could have the features of either lacune or striatocapsular infarction. Although they have similar morphologic character istics but they are presumed to have different pathophysiologic mechanism.
文摘目的探讨重复经颅磁刺激对基底节区脑梗死后执行功能障碍患者姿势控制能力的改善效果。方法选取2021年9月至2022年12月首都医科大学附属北京天坛医院收治的60例基底节区脑梗死后执行功能障碍患者为研究对象,采用随机数字表法分为试验组和对照组,每组30例。对照组给予常规康复治疗,试验组在对照组的基础上联合重复经颅磁刺激治疗。比较分析两组患者治疗前后的执行功能[斯特鲁普色词测试(Stroop color-word test,SCWT)耗时数、SCWT干扰量耗时数],姿势控制能力[10米步行测试(10-meter walking test,10MWT)、起立-行走计时测试(timed up and go test,TUGT)、Berg平衡量表(Berg balance scale,BBS)评分]以及步态参数(步长、步宽、前后位置和左右对称位置)。结果治疗2周后,试验组患者的SWCT耗时数和SWCT干扰量耗时数均显著短于治疗前(P<0.05),且试验组显著短于对照组(P<0.05)。治疗前后,两组患者的10MWT、步长、步宽和前后位置比较差异均无显著性(P>0.05)。治疗2周后,两组患者的BBS评分均显著高于治疗前(P<0.05),且试验组显著高于对照组(P<0.05);试验组患者的TUGT显著优于治疗前(P<0.05),而两组患者的TUGT比较差异无显著性(P>0.05);两组患者的左右对称位置均显著小于治疗前(P<0.05),且试验组显著小于对照组(P<0.05)。结论重复经颅磁刺激可改善基底节区脑梗死患者的执行功能障碍,同时可提高姿势控制能力,改善步态对称性。
