Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the re ported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case i...Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the re ported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6- day- old fem ale neonate presenting with lethargy, poor feeding, constipation, abdominal dist ention, and rectal bleeding. She was operated on with the impression of intestin al obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well- defined and round 3- cm mass in the cecal area. Diagnosis was m ade by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c- kit but negative for all other markers (desmin , actin, S100, NSE, and CD- 34). So the case was an undifferentiated GIST. Afte r 1 year of follow- up the patient was completely normal.展开更多
In contrast to common colonic epithelial neoplasms, polypoid mesenchymal tumors of the colon are extremely rare. The majority of uncommon gastrointestinal mesenchymal tumors are associated with the so-called gastroint...In contrast to common colonic epithelial neoplasms, polypoid mesenchymal tumors of the colon are extremely rare. The majority of uncommon gastrointestinal mesenchymal tumors are associated with the so-called gastrointestinal stromal tumors (GIST). We present a case of a rare colonic pleomorphic sarcoma, macroscopically mimicking a common epithelial colonic polyp, which did not match the criteria of GIST. In this case report we discuss the clinical and pathological characteristics of a rare polypoid-shaped, pleomorphic colonic sarcoma and refer a mark-off to other rare mesenchymal neoplasms of the gut.展开更多
Matrical differentiation in basal cell carcinoma (BCC) is rare. Only nine cases have been described that showed typical diagnostic features of BCC. in addition to shadow cells indicating hair- matrix differentiation. ...Matrical differentiation in basal cell carcinoma (BCC) is rare. Only nine cases have been described that showed typical diagnostic features of BCC. in addition to shadow cells indicating hair- matrix differentiation. These cases often present a diagnostic challenge due to confusion with pilomatrixoma or pilomatrix carcinoma. We present a case of BCC with matrical differentiation in a 78- year- old man. Immunohistochemical and molecular methods are used to differentiate this lesion from benign or malignant forms of pilomatrixoma.展开更多
文摘Gastrointestinal stromal tumor (GIST) is very rare in infancy. Most of the re ported cases in the literature are in adults; some are in children but there are a few reported cases in the literature. The present case is a 6- day- old fem ale neonate presenting with lethargy, poor feeding, constipation, abdominal dist ention, and rectal bleeding. She was operated on with the impression of intestin al obstruction, and right hemicolectomy was performed on her. Surgical specimen showed a well- defined and round 3- cm mass in the cecal area. Diagnosis was m ade by histologic and immunohistochemical studies which showed a GIST. The tumor showed positive vimentin and c- kit but negative for all other markers (desmin , actin, S100, NSE, and CD- 34). So the case was an undifferentiated GIST. Afte r 1 year of follow- up the patient was completely normal.
文摘In contrast to common colonic epithelial neoplasms, polypoid mesenchymal tumors of the colon are extremely rare. The majority of uncommon gastrointestinal mesenchymal tumors are associated with the so-called gastrointestinal stromal tumors (GIST). We present a case of a rare colonic pleomorphic sarcoma, macroscopically mimicking a common epithelial colonic polyp, which did not match the criteria of GIST. In this case report we discuss the clinical and pathological characteristics of a rare polypoid-shaped, pleomorphic colonic sarcoma and refer a mark-off to other rare mesenchymal neoplasms of the gut.
文摘Matrical differentiation in basal cell carcinoma (BCC) is rare. Only nine cases have been described that showed typical diagnostic features of BCC. in addition to shadow cells indicating hair- matrix differentiation. These cases often present a diagnostic challenge due to confusion with pilomatrixoma or pilomatrix carcinoma. We present a case of BCC with matrical differentiation in a 78- year- old man. Immunohistochemical and molecular methods are used to differentiate this lesion from benign or malignant forms of pilomatrixoma.
