In asymmetric rolling(ASR) the circumferential velocities of the working rolls are different. This yields a complex deformation mode with shear, compression and rigid body rotation components. The main microstructural...In asymmetric rolling(ASR) the circumferential velocities of the working rolls are different. This yields a complex deformation mode with shear, compression and rigid body rotation components. The main microstructural modification is on crystallographic texture, and, for aluminium alloys, this may improve the deformability after recrystallization. This work correlated the process variables, thickness reduction per pass(TRP) and velocity ratio between the upper and bottom rolls, with the texture development and the plastic properties after annealing. Finite element(FE) simulations were performed to quantify the influence of the strain components. Experimental data on texture, and plastic anisotropy were analyzed. In the sheet centre a crystallographic rotation of the compression components about the TD(transverse direction) axis was obtained, which yielded the development of {111}//ND(normal direction) texture components. On the surfaces the local variation of the velocity gradients caused an extra rotation component about ND. This yielded the increment of rotated cube components. After annealing the main texture components at the sheet centre were maintained and the texture intensity decreased. The planar anisotropy(△r) was reduced but the normal anisotropy and deep drawability obtained by the Erichsen test were similar for all conditions. The most favourable reduction of △r was obtained at a velocity ratio of 1.5 and TRP of 10%.展开更多
An incrementally nonlinear hypoplastic constitutive model was introduced, which was developed without recourse to the concepts in elastoplasticity theory such as yield surface, plastic potential and the decomposition ...An incrementally nonlinear hypoplastic constitutive model was introduced, which was developed without recourse to the concepts in elastoplasticity theory such as yield surface, plastic potential and the decomposition of the deformation into elastic and plastic parts. Triaxial drained tests on rockfill were conducted on a large scale triaxial apparatus under two types of stress paths, which were the stress paths of constant stress ratio and the complex stress paths with transitional features. Motivated by the effect of stress path, the Gudehus-Bauer hypoplastic model was improved by considering the parameter variations with different ratios of stress increment. Fitting parameter a presents a piecewise linear relationship with cosine of the slope angle θ determined by instantaneous stress path. The improved hypoplastic model can present peak stress increasing and volumetric strain changing from dilatancy to contractancy with the increase of transitional confining pressure σ3t and the decrease of slope angle θ of stress path. Compared with the test data, it is shown that the model is capable of fully considering the effect of stress path on rockfill.展开更多
Mesenchymal stem cell differentiation towards osteogenic, chondrogenic and adipogenic lineages have been extensively described and reproduced in the literature. In contrast, cardiomyogenic differentiation still remain...Mesenchymal stem cell differentiation towards osteogenic, chondrogenic and adipogenic lineages have been extensively described and reproduced in the literature. In contrast, cardiomyogenic differentiation still remains largely controversial. In this study the authors aim to shed new light into this unclear phenomenon and test whether BMMSC （bone marrow mesenchymal stem cells） and ATMSC （adipose tissue derived mesenchymal stem cells） are able to differentiate into functional cardiomyocytes, investigating two differentiation protocols. AT and BMMSC behaved differently when cultured in differentiation media and presented lower levels of proliferation and alkaline phosphatase production, expression of cardiomyocyte-specific transcription factors such as GATA-4, Nkx2-5 and proteins such as ct and 13 Myosin Heavy Chains. Furthermore, MSC started to express higher levels of Connexin-43 and c~ sarcomeric actinin protein. Unfortunately, though, MSC did not present cardiomyocyte-like electrophysiological properties. In order to analyze a possible explanation for such limited plasticity, the authors decided to address the issue using a quantitative approach. Gene expression was quantified by Real time PCR, and, for the first time, the authors show that a possible explanation for limited plasticity of MSC is that even though differentiated cells presented differential gene expression, the levels of key cardiomyogenic genes did not reach expression levels presented by adult cardiomyocytes, nor were maintained along differentiation, reaching peaks at 4 days of stimulation, and decaying thereafter.展开更多
Using Fourier transform infrared spectroscopy(FTIR),we measured water contents in quartz and feldspar for four kinds of felsic rocks,i.e.,undeformed granite,banded granitic gneiss,fine-grained felsic mylonite,and fine...Using Fourier transform infrared spectroscopy(FTIR),we measured water contents in quartz and feldspar for four kinds of felsic rocks,i.e.,undeformed granite,banded granitic gneiss,fine-grained felsic mylonite,and fine-grained quartz-mica schist,collected from Pengguan Complex and Kangding Complex in the Longmenshan tectonic zone,Sichuan,China.The absorbance spectra suggest that water in coarse-grained quartz and feldspar of undeformed granite and banded granitic gneiss occurs mainly as hydroxyl in crystal defects,and water in most of fine-grained quartz and feldspar of felsic mylonite is molecular water in inclusions and liquid-type water in grain boundaries,but in some cases it still occurs as hydroxyl in crystal defects.Water content of quartz in undeformed granite is 0.001 wt%-0.009 wt %,and that of feldspar 0.005 wt%-0.02 wt%.The banded granitic gneiss shows water contents of 0.002 wt%-0.011 wt% in quartz and 0.012 wt%-0.036 wt% in feldspar.Quartz ribbon and feldspar ribbon in fine-grained felsic mylonite show that their water contents are similar to those of coarse-grained quartz and feldspar in granite,0.002 wt%-0.011 wt%,and 0.004 wt%-0.02 wt%,respectively.Water contents of fine-grained quartz and feldspar are respectively 0.004 wt%-0.02 wt% and 0.012 wt%-0.06 wt%.Water content of quartz in fine-grained quartz-mica schist is 0.007 wt%-0.15 wt%.Water-bearing minerals display much higher water contents than those of nominally anhydrous minerals,and the percentage of water-bearing minerals in felsic rocks increases with the strain of rocks.These new data indicate that hydroxyl in crystal defects has basically not been released during the shear deformation,and on the contrary,the increase in molecular water in inclusions and liquid-type water in grain boundaries as well as water-bearing minerals after shear deformation leads to a significant increase of the water content in deformed rocks.Based on data of creep tests,it is inferred here that the fine-grained mylonites with more water have much lower strength than that of the weakly deformed coarse-grained rocks in the middle crust,and this indicates that trace amount of water significantly helped develop the ductile shear zone.展开更多
Experimental investigation and numerical modeling on elasto-plastic notch-root stress/strain distributions under monotonic loadings of both the Ni-based directionally solidified(DS)superalloy and Titanium alloy were c...Experimental investigation and numerical modeling on elasto-plastic notch-root stress/strain distributions under monotonic loadings of both the Ni-based directionally solidified(DS)superalloy and Titanium alloy were carried out simultaneously.For measuring inhomogeneous deformation fields at notch roots,an optical-numerical full-field surface deformation measurement system was developed based on the digital image correlation(DIC)method.The obtained strain distributions were then verified with reasonable accuracy by finite element simulation,where an anisotropic elastic-viscoplastic constitutive model was developed for DS superalloy and a simple isotropic stress-strain relationship was adopted for Titanium alloy.Meanwhile,factors affecting elasto-plastic notch-root stress/strain distributions were systematically investigated numerically,where the emphasis was placed on temperature,loading stress rate,sample shape,anisotropy and notch features.The results show that stress/strain behavior at notch root is significantly affected by the mentioned factors,which are concretely embodied in the distribution of tensile stress/strain,equivalent stress and accumulative equivalent plastic strain.展开更多
基金supported by Sao Paulo State Research Foundation (FAPESP 2016/10997-0)by CAPES–Brazil
文摘In asymmetric rolling(ASR) the circumferential velocities of the working rolls are different. This yields a complex deformation mode with shear, compression and rigid body rotation components. The main microstructural modification is on crystallographic texture, and, for aluminium alloys, this may improve the deformability after recrystallization. This work correlated the process variables, thickness reduction per pass(TRP) and velocity ratio between the upper and bottom rolls, with the texture development and the plastic properties after annealing. Finite element(FE) simulations were performed to quantify the influence of the strain components. Experimental data on texture, and plastic anisotropy were analyzed. In the sheet centre a crystallographic rotation of the compression components about the TD(transverse direction) axis was obtained, which yielded the development of {111}//ND(normal direction) texture components. On the surfaces the local variation of the velocity gradients caused an extra rotation component about ND. This yielded the increment of rotated cube components. After annealing the main texture components at the sheet centre were maintained and the texture intensity decreased. The planar anisotropy(△r) was reduced but the normal anisotropy and deep drawability obtained by the Erichsen test were similar for all conditions. The most favourable reduction of △r was obtained at a velocity ratio of 1.5 and TRP of 10%.
基金Projects(50479057, 50639060) supported by the National Natural Science Foundation of China
文摘An incrementally nonlinear hypoplastic constitutive model was introduced, which was developed without recourse to the concepts in elastoplasticity theory such as yield surface, plastic potential and the decomposition of the deformation into elastic and plastic parts. Triaxial drained tests on rockfill were conducted on a large scale triaxial apparatus under two types of stress paths, which were the stress paths of constant stress ratio and the complex stress paths with transitional features. Motivated by the effect of stress path, the Gudehus-Bauer hypoplastic model was improved by considering the parameter variations with different ratios of stress increment. Fitting parameter a presents a piecewise linear relationship with cosine of the slope angle θ determined by instantaneous stress path. The improved hypoplastic model can present peak stress increasing and volumetric strain changing from dilatancy to contractancy with the increase of transitional confining pressure σ3t and the decrease of slope angle θ of stress path. Compared with the test data, it is shown that the model is capable of fully considering the effect of stress path on rockfill.
文摘Mesenchymal stem cell differentiation towards osteogenic, chondrogenic and adipogenic lineages have been extensively described and reproduced in the literature. In contrast, cardiomyogenic differentiation still remains largely controversial. In this study the authors aim to shed new light into this unclear phenomenon and test whether BMMSC （bone marrow mesenchymal stem cells） and ATMSC （adipose tissue derived mesenchymal stem cells） are able to differentiate into functional cardiomyocytes, investigating two differentiation protocols. AT and BMMSC behaved differently when cultured in differentiation media and presented lower levels of proliferation and alkaline phosphatase production, expression of cardiomyocyte-specific transcription factors such as GATA-4, Nkx2-5 and proteins such as ct and 13 Myosin Heavy Chains. Furthermore, MSC started to express higher levels of Connexin-43 and c~ sarcomeric actinin protein. Unfortunately, though, MSC did not present cardiomyocyte-like electrophysiological properties. In order to analyze a possible explanation for such limited plasticity, the authors decided to address the issue using a quantitative approach. Gene expression was quantified by Real time PCR, and, for the first time, the authors show that a possible explanation for limited plasticity of MSC is that even though differentiated cells presented differential gene expression, the levels of key cardiomyogenic genes did not reach expression levels presented by adult cardiomyocytes, nor were maintained along differentiation, reaching peaks at 4 days of stimulation, and decaying thereafter.
基金supported by National Natural Science Foundation of China(Grant No.40972146)State Key Laboratory of Earthquake Dynamics(Grant Nos. LED2009A01,LED2008A03)
文摘Using Fourier transform infrared spectroscopy(FTIR),we measured water contents in quartz and feldspar for four kinds of felsic rocks,i.e.,undeformed granite,banded granitic gneiss,fine-grained felsic mylonite,and fine-grained quartz-mica schist,collected from Pengguan Complex and Kangding Complex in the Longmenshan tectonic zone,Sichuan,China.The absorbance spectra suggest that water in coarse-grained quartz and feldspar of undeformed granite and banded granitic gneiss occurs mainly as hydroxyl in crystal defects,and water in most of fine-grained quartz and feldspar of felsic mylonite is molecular water in inclusions and liquid-type water in grain boundaries,but in some cases it still occurs as hydroxyl in crystal defects.Water content of quartz in undeformed granite is 0.001 wt%-0.009 wt %,and that of feldspar 0.005 wt%-0.02 wt%.The banded granitic gneiss shows water contents of 0.002 wt%-0.011 wt% in quartz and 0.012 wt%-0.036 wt% in feldspar.Quartz ribbon and feldspar ribbon in fine-grained felsic mylonite show that their water contents are similar to those of coarse-grained quartz and feldspar in granite,0.002 wt%-0.011 wt%,and 0.004 wt%-0.02 wt%,respectively.Water contents of fine-grained quartz and feldspar are respectively 0.004 wt%-0.02 wt% and 0.012 wt%-0.06 wt%.Water content of quartz in fine-grained quartz-mica schist is 0.007 wt%-0.15 wt%.Water-bearing minerals display much higher water contents than those of nominally anhydrous minerals,and the percentage of water-bearing minerals in felsic rocks increases with the strain of rocks.These new data indicate that hydroxyl in crystal defects has basically not been released during the shear deformation,and on the contrary,the increase in molecular water in inclusions and liquid-type water in grain boundaries as well as water-bearing minerals after shear deformation leads to a significant increase of the water content in deformed rocks.Based on data of creep tests,it is inferred here that the fine-grained mylonites with more water have much lower strength than that of the weakly deformed coarse-grained rocks in the middle crust,and this indicates that trace amount of water significantly helped develop the ductile shear zone.
基金supported by the National Natural Science Foundation of China(Grant No.51275023)the Innovation Foundation of BUAA for PhD Graduates(Grant No.YWF-14-YJSY-49)
文摘Experimental investigation and numerical modeling on elasto-plastic notch-root stress/strain distributions under monotonic loadings of both the Ni-based directionally solidified(DS)superalloy and Titanium alloy were carried out simultaneously.For measuring inhomogeneous deformation fields at notch roots,an optical-numerical full-field surface deformation measurement system was developed based on the digital image correlation(DIC)method.The obtained strain distributions were then verified with reasonable accuracy by finite element simulation,where an anisotropic elastic-viscoplastic constitutive model was developed for DS superalloy and a simple isotropic stress-strain relationship was adopted for Titanium alloy.Meanwhile,factors affecting elasto-plastic notch-root stress/strain distributions were systematically investigated numerically,where the emphasis was placed on temperature,loading stress rate,sample shape,anisotropy and notch features.The results show that stress/strain behavior at notch root is significantly affected by the mentioned factors,which are concretely embodied in the distribution of tensile stress/strain,equivalent stress and accumulative equivalent plastic strain.
