目的探讨三维同步非增强血管造影和斑块内出血(threedimensionalsimultaneous noncontrast angiography and intra plaque hemorrhage,3D-SNAP)高分辨磁共振成像技术对颅内动脉夹层的诊断价值。材料与方法连续收集2015年1月至2018年3月...目的探讨三维同步非增强血管造影和斑块内出血(threedimensionalsimultaneous noncontrast angiography and intra plaque hemorrhage,3D-SNAP)高分辨磁共振成像技术对颅内动脉夹层的诊断价值。材料与方法连续收集2015年1月至2018年3月陕西省人民医院神经内科43例后循环短暂性脑缺血发作(transientischemicattack,TIA)或脑梗死患者,其中颅内动脉夹层18例,非动脉夹层25例,所有患者均采用PhilipsIngenia 3.0 T MRI获取TOF-MRA、T1WI-VISTA、T2WI、3D-SNAP、CE-T1WI成像,双盲分析各序列颅内动脉夹层征象。采用卡方检验、独立样本t检验分析夹层组与非夹层组临床基本资料以及夹层组各序列影像学特征;利用受试者工作特征(receiveroperating characteristic,ROC)曲线比较各序列对颅内动脉夹层的诊断效能。结果 (1)夹层组年龄较非夹层组低,差异有统计学意义(P<0.05),两组间性别、血压、糖尿病、吸烟差异均无统计学意义。(2)6例患者在TOF-MRA、T2WI、T1WI-VISTA、SNAP及CE-T1WI成像序列同时显示夹层瘤样扩张、真假腔、壁内血肿、内膜瓣征象;颅内动脉夹层壁内血肿、双腔征及内膜瓣显示率高分辨MRI各序列比较差异有统计学意义(P<0.05),SNAP显示壁内血肿最敏感,CE-T1WI显示双腔征、内膜瓣征最敏感。(3) TOF-MRA、T2WI、T1WI-VISTA、3D-SNAP、CE-T1WI、SNAP联合CE-T1WI成像序列诊断颅内动脉夹层ROC曲线下面积分别为0.663、0.492、0.729、0.741、0.752、0.824。结论 3D-SNAP高分辨磁共振成像技术无创性、有效评价颅内动脉夹层具有无限的潜力和广阔的前景。展开更多
Complex cyber-physical network refers to a new generatio~ of complex networks whose normal functioning significantly relies on tight interactions between its physical and cyber compo- nents. Many modern critical infra...Complex cyber-physical network refers to a new generatio~ of complex networks whose normal functioning significantly relies on tight interactions between its physical and cyber compo- nents. Many modern critical infrastructures can be appropriately modelled as complex cyber-physical networks. Typical examples of such infrastructures are electrical power grids, WWW, public trans- portation systems, state financial networks, and the Interact. These critical facilities play important roles in ensuring the stability of society as well as the development of economy. Advances in informa- tion and communication technology open opportunities for malicious attackers to launch coordinated attacks on cyber-physical critical facilities in networked infrastructures from any Interact-accessible place. Cybersecurity of complex cyber-physical networks has emerged as a hot topic within this con- text. In practice, it is also very crucial to understand the interplay between the evolution of underlying network structures and the collective dynamics on these complex networks and consequently to design efficient security control strategies to protect the evolution of these networks. In this paper, cybersecu- rity of complex cyber-physical networks is first outlined and then some security enhancing techniques, with particular emphasis on safety communications, attack detection and fault-tolerant control, are suggested. Furthermore, a new class of efficient secure the achievement of desirable pinning synchronization control strategies are proposed for guaranteeing behaviors in complex cyber-physical networks against malicious attacks on nodes. The authors hope that this paper motivates to design enhanced security strategies for complex cyber-physical network systems, to realize resilient and secure critical infrastructures.展开更多
基金Supported by the project of WUSE under grant number 20073201the Startup Found for NSFC in WUSEthe NSF of Hubei Province under grant number 2007ABA348~~
文摘目的探讨三维同步非增强血管造影和斑块内出血(threedimensionalsimultaneous noncontrast angiography and intra plaque hemorrhage,3D-SNAP)高分辨磁共振成像技术对颅内动脉夹层的诊断价值。材料与方法连续收集2015年1月至2018年3月陕西省人民医院神经内科43例后循环短暂性脑缺血发作(transientischemicattack,TIA)或脑梗死患者,其中颅内动脉夹层18例,非动脉夹层25例,所有患者均采用PhilipsIngenia 3.0 T MRI获取TOF-MRA、T1WI-VISTA、T2WI、3D-SNAP、CE-T1WI成像,双盲分析各序列颅内动脉夹层征象。采用卡方检验、独立样本t检验分析夹层组与非夹层组临床基本资料以及夹层组各序列影像学特征;利用受试者工作特征(receiveroperating characteristic,ROC)曲线比较各序列对颅内动脉夹层的诊断效能。结果 (1)夹层组年龄较非夹层组低,差异有统计学意义(P<0.05),两组间性别、血压、糖尿病、吸烟差异均无统计学意义。(2)6例患者在TOF-MRA、T2WI、T1WI-VISTA、SNAP及CE-T1WI成像序列同时显示夹层瘤样扩张、真假腔、壁内血肿、内膜瓣征象;颅内动脉夹层壁内血肿、双腔征及内膜瓣显示率高分辨MRI各序列比较差异有统计学意义(P<0.05),SNAP显示壁内血肿最敏感,CE-T1WI显示双腔征、内膜瓣征最敏感。(3) TOF-MRA、T2WI、T1WI-VISTA、3D-SNAP、CE-T1WI、SNAP联合CE-T1WI成像序列诊断颅内动脉夹层ROC曲线下面积分别为0.663、0.492、0.729、0.741、0.752、0.824。结论 3D-SNAP高分辨磁共振成像技术无创性、有效评价颅内动脉夹层具有无限的潜力和广阔的前景。
基金supported by the National Key Research and Development Program of China under Grant No.2016YFB0800401the National Nature Science Foundation of China under Grant Nos.61304168,61673104,and 61322302+3 种基金the Natural Science Foundation of Jiangsu Province of China under Grant No.BK20130595the National Ten Thousand Talent Program for Young Top-Notch Talents,the Six Talent Peaks of Jiangsu Province of China under Grant No.2014-DZXX-004the Doctoral Program of Higher Education of China under Grant No.20130092120030the Fundamental Research Funds for the Central Universities of China under Grant No.2242016K41030
文摘Complex cyber-physical network refers to a new generatio~ of complex networks whose normal functioning significantly relies on tight interactions between its physical and cyber compo- nents. Many modern critical infrastructures can be appropriately modelled as complex cyber-physical networks. Typical examples of such infrastructures are electrical power grids, WWW, public trans- portation systems, state financial networks, and the Interact. These critical facilities play important roles in ensuring the stability of society as well as the development of economy. Advances in informa- tion and communication technology open opportunities for malicious attackers to launch coordinated attacks on cyber-physical critical facilities in networked infrastructures from any Interact-accessible place. Cybersecurity of complex cyber-physical networks has emerged as a hot topic within this con- text. In practice, it is also very crucial to understand the interplay between the evolution of underlying network structures and the collective dynamics on these complex networks and consequently to design efficient security control strategies to protect the evolution of these networks. In this paper, cybersecu- rity of complex cyber-physical networks is first outlined and then some security enhancing techniques, with particular emphasis on safety communications, attack detection and fault-tolerant control, are suggested. Furthermore, a new class of efficient secure the achievement of desirable pinning synchronization control strategies are proposed for guaranteeing behaviors in complex cyber-physical networks against malicious attacks on nodes. The authors hope that this paper motivates to design enhanced security strategies for complex cyber-physical network systems, to realize resilient and secure critical infrastructures.
