Adipose-derived mesenchymal stem cells (ADSCs) can be largely and easily obtained from a wide range of sources. Moreover, they have self-renewal ability, multi-differentiation potential, and an important role in imm...Adipose-derived mesenchymal stem cells (ADSCs) can be largely and easily obtained from a wide range of sources. Moreover, they have self-renewal ability, multi-differentiation potential, and an important role in immune regulation. They can secrete a variety of cytokines to regulate the in vivo micro-environment. Therefore, ADSCs are the ideal seed ceils for stem ceils application. This paper reviews the location, isolation, surface markers, proliferation, differentiation and other biological characteristics of ADSCs, as well as their secretory function and relative researches. ADSCs are expected to become excellent seed cells for cell therapy and tissue engineering through in-depth studies.展开更多
Dynamic optimization problems(DOPs) described by differential equations are often encountered in chemical engineering. Deterministic techniques based on mathematic programming become invalid when the models are non-di...Dynamic optimization problems(DOPs) described by differential equations are often encountered in chemical engineering. Deterministic techniques based on mathematic programming become invalid when the models are non-differentiable or explicit mathematical descriptions do not exist. Recently, evolutionary algorithms are gaining popularity for DOPs as they can be used as robust alternatives when the deterministic techniques are invalid. In this article, a technology named ranking-based mutation operator(RMO) is presented to enhance the previous differential evolution(DE) algorithms to solve DOPs using control vector parameterization. In the RMO, better individuals have higher probabilities to produce offspring, which is helpful for the performance enhancement of DE algorithms. Three DE-RMO algorithms are designed by incorporating the RMO. The three DE-RMO algorithms and their three original DE algorithms are applied to solve four constrained DOPs from the literature. Our simulation results indicate that DE-RMO algorithms exhibit better performance than previous non-ranking DE algorithms and other four evolutionary algorithms.展开更多
China has achieved a political consensus around the need to transform the path of economic growth toward one that lowers carbon intensity and ultimately leads to reductions in carbon emissions, but there remain differ...China has achieved a political consensus around the need to transform the path of economic growth toward one that lowers carbon intensity and ultimately leads to reductions in carbon emissions, but there remain different views on pathways that could achieve such a transformation. The essential question is whether radical or incremental reforms are required in the coming decades. This study explores relevant pathways in China beyond 2020, particularly modeling the major target choices of carbon emission peaking in China around 2030 as China-US Joint Announcement by an integrated assessment model for climate change IAMC based on carbon factor theory. Here scenarios DGS-2020, LGS2025, LBS-2030 and DBS-2040 derived from the historical pathways of developed countries are developed to access the comprehensive impacts on the economy, energy and climate security for the greener development in China. The findings suggest that the period of 2025--2030 is the window of opportunity to achieve a peak in carbon emissions at a level below 12 Gt CO2 and 8.5 t per capita by reasonable trade-offs from economy growth, annually -0.2% in average and cumulatively -3% deviation to BAU in 2030. The oil and natural gas import dependence will exceed 70% and 45% respectively while the non-fossil energy and electricity share will rise to above 20% and 45%. Meantime, the electrification level in end use sectors will increase substantially and the electricity energy ratio approaching 50%, the labor and capital productivity should be double in improvements and the carbon intensity drop by 65% by 2030 compared to the 2005 level, and the cumulative emission reductions are estimated to be more than 20 Gt CO2 in 2015-2030.展开更多
The denitrifying sulfide removal(DSR) process with bio-granules comprising both heterotrophic and autotrophic denitrifiers can simultaneously convert nitrate, sulfide and acetate species into di-nitrogen gas, elementa...The denitrifying sulfide removal(DSR) process with bio-granules comprising both heterotrophic and autotrophic denitrifiers can simultaneously convert nitrate, sulfide and acetate species into di-nitrogen gas, elemental sulfur and carbon dioxide, respectively, at high loading rates. This study has determined that the reaction rate of sulfide oxidized into sulfur could be enhanced in the presence of 1,2-naphthoquinone-4-sulphonate(NQS). The presence of NQS mitigated the inhibition effects of sulfide species on denitrification. Furthermore, the reaction rates of nitrate and acetate to nitrogen gas and CO_2, respectively, were also promoted in the presence of NQS, thereby enhancing the performance of DSR granules. The advantages and disadvantages of applying the NQS-DSR process are discussed.展开更多
AIM:To assess the impact of guidelines for albumin prescription in an academic hospital,which is a referral center for liver diseases.METHODS:Although randomized trials and guidelines support albumin administration fo...AIM:To assess the impact of guidelines for albumin prescription in an academic hospital,which is a referral center for liver diseases.METHODS:Although randomized trials and guidelines support albumin administration for some complications of cirrhosis,the high cost of albumin greatly limits its use in clinical practice.In 2003,a multidisciplinary panel at Sant'Orsola-Malpighi University Hospital(Bologna,Italy)used a literature-based consensus method to list all the acute and chronic conditions for which albumin is indicated as first-or second-line treatment.Indications in hepatology included prevention of post-paracentesis circulatory dysfunction and renal failure induced by spontaneous bacterial peritonitis,and treatment of hepatorenal syndrome and refractory ascites.Although still debated,albumin administration in refractory ascites is accepted by the Italian health care system.We analyzedalbumin prescription and related costs before and after implementation of the new guidelines.RESULTS:While albumin consumption and costs doubled from 1998 to 2002,they dropped 20%after 2003,and remained stable for the following 6 years.Complications of cirrhosis,namely refractory ascites and paracentesis,represented the predominant indications,followed by major surgery,shock,enteric diseases,and plasmapheresis.Albumin consumption increased significantly after guideline implementation in the liver units,whereas it declined elsewhere in the hospital.Lastly,extra-protocol albumin prescription was estimated as<10%.CONCLUSION:Albumin administration in cirrhosis according to international guidelines does not increase total hospital albumin consumption if its use in settings without evidence of efficacy is avoided.展开更多
Abstract: An effective approach was conducted for estimating fracture toughness using the crack opening displacement (COD) method for plasma enhanced chemical vapor deposition (PECVD) coating materials. For this ...Abstract: An effective approach was conducted for estimating fracture toughness using the crack opening displacement (COD) method for plasma enhanced chemical vapor deposition (PECVD) coating materials. For this evaluation, an elastoplastic analysis was used to estimate critical COD values for single edge notched bending (SENB) specimens. The relationship between fracture toughness (Kic) and critical COD for SENB specimens was obtained. Microstructure of the interface between AleO3-TiO2 composite ceramic coatings and AISI 1045 steel substrates was studied by using scanning electron microscope (SEM). Chemical compositions were clarified by energy-dispersive X-ray spectroscopy (EDS). The results show that the interface between of Al203-TiO2 and substrate has mechanical combining. The nanohardness of the coatings can reach 1 200 GPa examined by nanoindentation. The Klc was calculated according to this relationship from critical COD. The bending process produces a significant relationship of COD independent of the axial force applied. Fractographic analysis was conducted to determine the crack length. From the physical analysis of nanoindentation curves, the elastic modulus of 1045/AI2O3-TiO2 is 180 GPa for the 50 μm film. The highest value of fracture toughness for 1045/A1203-TiO2-250 μm is 348 MPa·mv2.展开更多
Improving cell efficiency and increasing throughput in solar cell industry efforts were put on uniform texturization and optimum diffusion process. To reduce reflectivity, NaOH/KOH (sodium hydroxide/potassium hydrox...Improving cell efficiency and increasing throughput in solar cell industry efforts were put on uniform texturization and optimum diffusion process. To reduce reflectivity, NaOH/KOH (sodium hydroxide/potassium hydroxide) and IPA (isopropyl alcohol) are widely used in standard alkaline texturization of mono c-Si (crystalline silicon) (〈100〉 crystal orientation) wafers, where IPA promotes formation of uniform pyramidal structure but leads to unstable process. In this work, carbohydrates have been investigated as an additive in etchant solution. Moreover uniform phosphorus diffusion process for B2B (back to back) diffusion (loading two wafers in one single slot of quartz boat) has been investigated with single and multiple temperature plateaus. Impact of pre-oxygen step on phosphorus diffusion is investigated in which number of inactive phosphorus at the PSG (phosphosilicate glass)-Si interface is reduced. A batch of 156 PSQ (pseudo square) mono c-Si solar cells with 18%-18.20% efficiency was fabricated which is -0.3% higher than the standard process. The EL (electroluminescence image), reff (carrier effective life time), Voc (open circuit voltage), Isc (short circuit current), Pvk (peak power) and r/ (efficiency) have been examined and compared with standard.展开更多
A common problem in rabbit production is the occurrence of digestive disorders just after weaning, and fiber is well known to be bcncficiai for rabbit gastrointestinal health. In order to test the hypothesis that w...A common problem in rabbit production is the occurrence of digestive disorders just after weaning, and fiber is well known to be bcncficiai for rabbit gastrointestinal health. In order to test the hypothesis that whether the good points of fiber increases with its dietary content, three isoenergetic and isonitrogenous diets and ninety mixed-sex New Zealand rabbits weaned 35-d-old were used. The results can be concluded as following: (1) Average daily feed intake (ADFI) tended to increase (i〉=0.058) while average daily gain (ADG) (p=0.001) and feed conversion ratio (FCR) (p〈0.001) deteriorated with increasing dietary ADF content. The highest morbidity was observed in the rabbits fed the highest dietary ADF concentration. (2)A decreasing coefficient of total tract apparent digestibility (CTTAD) of dry matter (DM) and crude protein (CP) was obtained with the increase of dietary fiber level (p〈0.001 and =0.003). (3) A significant negative effect of treatments on sucrase and maltase activities in the jejunum was observed (p=0.001 and 0.003). (4) The volatile fatty acid (VFA) concentration (p=0.011) and butyric acid (% total VFA) (P=0.001) dropped while the NH3-N concentration (P〈0.001), pH (P=0.004) and acetic acid (% total VFA) (P〈0.001) increased with increasing dietary ADF. It was concluded that high fiber level was unfavorable to the rabbits in the first two weeks after weaning.展开更多
This paper suggests that a new approach should be taken for the development of China's service sector. Priorities for this include: appropriate objectives for service sector development, enhanced functionality, inte...This paper suggests that a new approach should be taken for the development of China's service sector. Priorities for this include: appropriate objectives for service sector development, enhanced functionality, integrated development between manufacturing and services, improved regional layout of the service sector, and the emergence of reputable brands and leading enterprises. Well-designed and effective industrial policies, as well as calls for major breakthroughs in institutional mechanisms, must support the development of the service sector. Additionally, excessive burdens and difficult financing channels need to be addressed. More attention should be paid to the construction of the credit system, service standardization, and service statistical accounting as element tasks.展开更多
The economic growth, energy structure and environmental capacity in China determine that CCS (carbon capture and storage) is an important strategic approach for China to confront the climate changes. In this paper, cu...The economic growth, energy structure and environmental capacity in China determine that CCS (carbon capture and storage) is an important strategic approach for China to confront the climate changes. In this paper, current status in China is firstly presented regarding policy making, technology research and development, pilot project and international cooperation. Then the opportunities of exploring CCS are analyzed from the viewpoint of application potentials, cost and China's circumstances. The challenges to CCS are pointed out with respect to energy consumption, technologies, funding and environment. Finally some suggestions are put forward on CCS development.展开更多
Photocatalytic degradation is one of the most promising remediation technologies in terms of advanced oxidation processes(AOPs) for water treatment. In this study, novel graphitic carbon nitride/titanium dioxide(gC3N4...Photocatalytic degradation is one of the most promising remediation technologies in terms of advanced oxidation processes(AOPs) for water treatment. In this study, novel graphitic carbon nitride/titanium dioxide(gC3N4/Ti O2) composites were synthesized by a facile sonication method. The physicochemical properties of the photocatalyst with different mass ratios of g-C3N4 to Ti O2 were investigated by X-ray diffraction(XRD), scanning electron microscope(SEM), transmission electron microscopy(TEM), N2 sorption, Fourier transform infrared spectroscopy(FT-IR), X-ray photoelectron spectroscopy(XPS), and UV–vis DRS. The photocatalytic performances were evaluated by degradation of methylene blue. It was found that g-C3N4/Ti O2 with a mass ratio of 1.5:1 exhibited the best degradation performance. Under UV, the degradation rate of g-C3N4/Ti O2 was 6.92 and 2.65 times higher than g-C3N4 and Ti O2, respectively. While under visible light, the enhancement factors became 9.27(to g-C3N4) and 7.03(to Ti O2). The improved photocatalytic activity was ascribed to the interfacial charge transfer between g-C3N4 and Ti O2. This work suggests that hybridization can produce promising solar materials for environmental remediation.展开更多
The performance of ion-exchange resin catalysts during isobutene (IB) dimerization was investigated under different IB contents,temperatures and liquid-volume hourly space velocity (LHSV) using a plug flow reactor in ...The performance of ion-exchange resin catalysts during isobutene (IB) dimerization was investigated under different IB contents,temperatures and liquid-volume hourly space velocity (LHSV) using a plug flow reactor in the absence of any selectivity enhancing component.High IB content and temperature resulted in a high conversion and C12 selectivity bu low C8 selectivity.The influence of LHSV was related with the IB content:LHSV had great effect at high IB content,while the performance of ion-exchange resin changed little with LHSV if IB content was low.The effect of water on the stability of resins was also studied.Desulfonation was observed during the C4 dimerization reaction when water was added to the feed.Chlorinated resin was more stable than conventional polystyrene-based resins during the test.展开更多
Since the introduction of"green tyres" in the early 90's, the use of silica as a reinforcing filler, along with a silane coupling agent, has spread and grown worldwide. The greatest advantage of using silica over c...Since the introduction of"green tyres" in the early 90's, the use of silica as a reinforcing filler, along with a silane coupling agent, has spread and grown worldwide. The greatest advantage of using silica over carbon black as reinforcing filler in a tyre tread compound is that a lower rolling resistance is achieved, while maintaining good wet traction. However, a previous study has shown that the wear resistance of a silica filled ENR (epoxidised natural rubber) compound was not as high as those of conventional OESBR (oil extended styrene butadiene rubber) and NR/BR compounds used in passenger car and truck tyre treads. In this work, with the aim of improving abrasion resistance, the effect of blending BR (butadiene rubber) into a silica filled ENR compound was studied. Blends with 0 to 30 phr BR were prepared in a Polylab Haake internal mixer. The rheological properties of the compounds were measured using a Mooney viscometer and oscillating-disc rheometer. The hardness, tensile strength and DIN abrasion resistance were also measured. The results showed that the ENR/silica compound properties such as tensile strength and hardness were as good as those of the conventional compounds. However, the most important finding was that abrasion resistance increased significantly with BR content, exceeding that of the conventional compound at BR: ENR ratios of greater than 20:80.展开更多
Photoelectrodes with a specific structure and composition have been proposed for improving the efficiency of solar water splitting. Here, a novel multijunction structure was fabricated, with Si nanowires as cores, ZnI...Photoelectrodes with a specific structure and composition have been proposed for improving the efficiency of solar water splitting. Here, a novel multijunction structure was fabricated, with Si nanowires as cores, ZnIn2S4 nanosheets as branches, and TiO2 films as sandwiched layers. This junction exhibited a superior photoelectrochemical performance with a maximum photoconversion efficiency of 0.51%, which is 795 and 64 times higher than that of a bare Si wafer and nanowires, respectively. The large enhancement was attributed to the effective electron-hole separation and fast excited carrier transport within the multijunctions resulting from their favorable energy band alignments with water redox potentials, and to the enlarged contact area for facilitating the electron transfer at the multijunction/electrolyte interface.展开更多
Near-infrared (NIR) photothermal therapy has developed very quickly in recent years. However, its clinical applications are hindered by many practical problems, such as low accumulation in tumors, high laser power d...Near-infrared (NIR) photothermal therapy has developed very quickly in recent years. However, its clinical applications are hindered by many practical problems, such as low accumulation in tumors, high laser power density and high biotoxicity in vivo. Herein, a versatile system combining chemotherapy with photothermal therapy for cancer therapy using ultrasmall Pd nanosheets (SPNS) has been developed. The SPNS can serve as pH-responsive drug carriers to efficiently deliver DOX into cancer cells and tumors. On the other hand, the coordinative loading of DOX on SPNS enhances its accumulation in tumor tissue. So we can efficiently ablate tumor using low-intensity laser radiation. Importantly, with ultrasmall size (-4.4 nm), SPNS surface-functionalized with reduced glutathione (GSH) can be cleared from the body through the renal system into the urine. This cancer therapeutic nanosystem, which exhibits a significant synergistic effect and low systemic toxicity, has great potential for clinical applications.展开更多
Supertetrahedral zinc-gallium-tin sulfide cluster modified with reduced graphene oxide protective layer was first synthesized, which exhibited an excellent photoelectrochemical performance and enhanced stability in co...Supertetrahedral zinc-gallium-tin sulfide cluster modified with reduced graphene oxide protective layer was first synthesized, which exhibited an excellent photoelectrochemical performance and enhanced stability in comparison to supertetrahedral clusters.展开更多
Objective: To promote stem cells differentiation into neurons and enhance neuromotor function after brain injury through brain-derived neurotrophic factor (BDNF) induction. Methods: Recombinant adenovirus vector ...Objective: To promote stem cells differentiation into neurons and enhance neuromotor function after brain injury through brain-derived neurotrophic factor (BDNF) induction. Methods: Recombinant adenovirus vector was applied to the transfection of BDNF into human-derived umbilical cord mesenchymal stem cells (UCMSCs). Enzyme linked immunosorbent assay (ELISA) was used to determine the secretion phase of BDNF. The brain injury model of athymic mice induced by hydraulic pressure percussion was established for transplantation of stem cells into the edge of injury site. Nerve function scores were obtained, and the expression level of transfected and non-transfected BDNF, proportion of neuron specific enolase (NSE) and glial fibrillary acidic protein (GFAP), and the number of apoptosis cells were compared respectively. Results: The BDNF expression achieved its stabilization at a high level 72 hours after gene transfection. The mouse obtained a better score of nerve function, and the proportion of the NSE-positive cells increased significantly (P〈0.05), but GFAP-positive cells decreased in BDNF- UCMSCs group compared with the other two groups (P〈0.05). At the site of high expression of BDNF, the number of apoptosis cells decreased markedly. Conclusion: BDNF gene can promote the differentiation of the stem cells into neurons rather than glial cells, and enhance neuromotor function after brain injury.展开更多
Al-doped ZnO (AZO) nanocrystalline aggregates (NCAs) were prepared by a low cost colloid chemistry method and effects of the Al-doped concentration on the morphological and structural properties of the AZO NCAs were s...Al-doped ZnO (AZO) nanocrystalline aggregates (NCAs) were prepared by a low cost colloid chemistry method and effects of the Al-doped concentration on the morphological and structural properties of the AZO NCAs were studied. The dye adsorption ability of the AZO NCAs with various Al-doped concentrations was also investigated. Results indicate that the doping of the Al ions not only does not change the wurtzite structure of the ZnO crystal but also can reduce the crystallite grain size and the particle size distribution of the NCAs, which gives them a higher specific surface area and dye adsorption ability than that of the ZnO NCAs. The as-prepared AZO NCAs would be a promising material to be applied in the dye sensitized solar cells and water treatment.展开更多
Visual imagery constitutes the most important sensory information for humans.The entire field of acquiring,analyzing and synthesizing visual data by means of computers is called visual computing.It has an extraordinar...Visual imagery constitutes the most important sensory information for humans.The entire field of acquiring,analyzing and synthesizing visual data by means of computers is called visual computing.It has an extraordinarily wide range of applications,including for example:industrial quality control,street view and driver assistance systems,robot navigation,multimedia systems,and computer games.展开更多
基金Supported by The Fund from the Endangered Species Import and Export Management Office of the People’s Republic of China for the Management and Research of Endangered Wild Animals(201441314404)~~
文摘Adipose-derived mesenchymal stem cells (ADSCs) can be largely and easily obtained from a wide range of sources. Moreover, they have self-renewal ability, multi-differentiation potential, and an important role in immune regulation. They can secrete a variety of cytokines to regulate the in vivo micro-environment. Therefore, ADSCs are the ideal seed ceils for stem ceils application. This paper reviews the location, isolation, surface markers, proliferation, differentiation and other biological characteristics of ADSCs, as well as their secretory function and relative researches. ADSCs are expected to become excellent seed cells for cell therapy and tissue engineering through in-depth studies.
基金Supported by the National Natural Science Foundation of China(61333010,61134007and 21276078)“Shu Guang”project of Shanghai Municipal Education Commission,the Research Talents Startup Foundation of Jiangsu University(15JDG139)China Postdoctoral Science Foundation(2016M591783)
文摘Dynamic optimization problems(DOPs) described by differential equations are often encountered in chemical engineering. Deterministic techniques based on mathematic programming become invalid when the models are non-differentiable or explicit mathematical descriptions do not exist. Recently, evolutionary algorithms are gaining popularity for DOPs as they can be used as robust alternatives when the deterministic techniques are invalid. In this article, a technology named ranking-based mutation operator(RMO) is presented to enhance the previous differential evolution(DE) algorithms to solve DOPs using control vector parameterization. In the RMO, better individuals have higher probabilities to produce offspring, which is helpful for the performance enhancement of DE algorithms. Three DE-RMO algorithms are designed by incorporating the RMO. The three DE-RMO algorithms and their three original DE algorithms are applied to solve four constrained DOPs from the literature. Our simulation results indicate that DE-RMO algorithms exhibit better performance than previous non-ranking DE algorithms and other four evolutionary algorithms.
基金supported by National Science and Technology Program"The Key Supporting Research of The International Negotiations on Climate Change and the Domestic Emission Reduction"(2012BAC20B04)
文摘China has achieved a political consensus around the need to transform the path of economic growth toward one that lowers carbon intensity and ultimately leads to reductions in carbon emissions, but there remain different views on pathways that could achieve such a transformation. The essential question is whether radical or incremental reforms are required in the coming decades. This study explores relevant pathways in China beyond 2020, particularly modeling the major target choices of carbon emission peaking in China around 2030 as China-US Joint Announcement by an integrated assessment model for climate change IAMC based on carbon factor theory. Here scenarios DGS-2020, LGS2025, LBS-2030 and DBS-2040 derived from the historical pathways of developed countries are developed to access the comprehensive impacts on the economy, energy and climate security for the greener development in China. The findings suggest that the period of 2025--2030 is the window of opportunity to achieve a peak in carbon emissions at a level below 12 Gt CO2 and 8.5 t per capita by reasonable trade-offs from economy growth, annually -0.2% in average and cumulatively -3% deviation to BAU in 2030. The oil and natural gas import dependence will exceed 70% and 45% respectively while the non-fossil energy and electricity share will rise to above 20% and 45%. Meantime, the electrification level in end use sectors will increase substantially and the electricity energy ratio approaching 50%, the labor and capital productivity should be double in improvements and the carbon intensity drop by 65% by 2030 compared to the 2005 level, and the cumulative emission reductions are estimated to be more than 20 Gt CO2 in 2015-2030.
基金supported bythe National Natural Science Foundation of China under Grant No. 21307160the Natural Science Foundation of Shandong Province under Grant No. ZR2013EEQ030
文摘The denitrifying sulfide removal(DSR) process with bio-granules comprising both heterotrophic and autotrophic denitrifiers can simultaneously convert nitrate, sulfide and acetate species into di-nitrogen gas, elemental sulfur and carbon dioxide, respectively, at high loading rates. This study has determined that the reaction rate of sulfide oxidized into sulfur could be enhanced in the presence of 1,2-naphthoquinone-4-sulphonate(NQS). The presence of NQS mitigated the inhibition effects of sulfide species on denitrification. Furthermore, the reaction rates of nitrate and acetate to nitrogen gas and CO_2, respectively, were also promoted in the presence of NQS, thereby enhancing the performance of DSR granules. The advantages and disadvantages of applying the NQS-DSR process are discussed.
文摘AIM:To assess the impact of guidelines for albumin prescription in an academic hospital,which is a referral center for liver diseases.METHODS:Although randomized trials and guidelines support albumin administration for some complications of cirrhosis,the high cost of albumin greatly limits its use in clinical practice.In 2003,a multidisciplinary panel at Sant'Orsola-Malpighi University Hospital(Bologna,Italy)used a literature-based consensus method to list all the acute and chronic conditions for which albumin is indicated as first-or second-line treatment.Indications in hepatology included prevention of post-paracentesis circulatory dysfunction and renal failure induced by spontaneous bacterial peritonitis,and treatment of hepatorenal syndrome and refractory ascites.Although still debated,albumin administration in refractory ascites is accepted by the Italian health care system.We analyzedalbumin prescription and related costs before and after implementation of the new guidelines.RESULTS:While albumin consumption and costs doubled from 1998 to 2002,they dropped 20%after 2003,and remained stable for the following 6 years.Complications of cirrhosis,namely refractory ascites and paracentesis,represented the predominant indications,followed by major surgery,shock,enteric diseases,and plasmapheresis.Albumin consumption increased significantly after guideline implementation in the liver units,whereas it declined elsewhere in the hospital.Lastly,extra-protocol albumin prescription was estimated as<10%.CONCLUSION:Albumin administration in cirrhosis according to international guidelines does not increase total hospital albumin consumption if its use in settings without evidence of efficacy is avoided.
基金Project supported by the National Research Foundation of Korea(2011-0030804)the Korea Research Foundation(KRF2009-0076450)funded by the Korea Government(MEST)
文摘Abstract: An effective approach was conducted for estimating fracture toughness using the crack opening displacement (COD) method for plasma enhanced chemical vapor deposition (PECVD) coating materials. For this evaluation, an elastoplastic analysis was used to estimate critical COD values for single edge notched bending (SENB) specimens. The relationship between fracture toughness (Kic) and critical COD for SENB specimens was obtained. Microstructure of the interface between AleO3-TiO2 composite ceramic coatings and AISI 1045 steel substrates was studied by using scanning electron microscope (SEM). Chemical compositions were clarified by energy-dispersive X-ray spectroscopy (EDS). The results show that the interface between of Al203-TiO2 and substrate has mechanical combining. The nanohardness of the coatings can reach 1 200 GPa examined by nanoindentation. The Klc was calculated according to this relationship from critical COD. The bending process produces a significant relationship of COD independent of the axial force applied. Fractographic analysis was conducted to determine the crack length. From the physical analysis of nanoindentation curves, the elastic modulus of 1045/AI2O3-TiO2 is 180 GPa for the 50 μm film. The highest value of fracture toughness for 1045/A1203-TiO2-250 μm is 348 MPa·mv2.
文摘Improving cell efficiency and increasing throughput in solar cell industry efforts were put on uniform texturization and optimum diffusion process. To reduce reflectivity, NaOH/KOH (sodium hydroxide/potassium hydroxide) and IPA (isopropyl alcohol) are widely used in standard alkaline texturization of mono c-Si (crystalline silicon) (〈100〉 crystal orientation) wafers, where IPA promotes formation of uniform pyramidal structure but leads to unstable process. In this work, carbohydrates have been investigated as an additive in etchant solution. Moreover uniform phosphorus diffusion process for B2B (back to back) diffusion (loading two wafers in one single slot of quartz boat) has been investigated with single and multiple temperature plateaus. Impact of pre-oxygen step on phosphorus diffusion is investigated in which number of inactive phosphorus at the PSG (phosphosilicate glass)-Si interface is reduced. A batch of 156 PSQ (pseudo square) mono c-Si solar cells with 18%-18.20% efficiency was fabricated which is -0.3% higher than the standard process. The EL (electroluminescence image), reff (carrier effective life time), Voc (open circuit voltage), Isc (short circuit current), Pvk (peak power) and r/ (efficiency) have been examined and compared with standard.
文摘A common problem in rabbit production is the occurrence of digestive disorders just after weaning, and fiber is well known to be bcncficiai for rabbit gastrointestinal health. In order to test the hypothesis that whether the good points of fiber increases with its dietary content, three isoenergetic and isonitrogenous diets and ninety mixed-sex New Zealand rabbits weaned 35-d-old were used. The results can be concluded as following: (1) Average daily feed intake (ADFI) tended to increase (i〉=0.058) while average daily gain (ADG) (p=0.001) and feed conversion ratio (FCR) (p〈0.001) deteriorated with increasing dietary ADF content. The highest morbidity was observed in the rabbits fed the highest dietary ADF concentration. (2)A decreasing coefficient of total tract apparent digestibility (CTTAD) of dry matter (DM) and crude protein (CP) was obtained with the increase of dietary fiber level (p〈0.001 and =0.003). (3) A significant negative effect of treatments on sucrase and maltase activities in the jejunum was observed (p=0.001 and 0.003). (4) The volatile fatty acid (VFA) concentration (p=0.011) and butyric acid (% total VFA) (P=0.001) dropped while the NH3-N concentration (P〈0.001), pH (P=0.004) and acetic acid (% total VFA) (P〈0.001) increased with increasing dietary ADF. It was concluded that high fiber level was unfavorable to the rabbits in the first two weeks after weaning.
文摘This paper suggests that a new approach should be taken for the development of China's service sector. Priorities for this include: appropriate objectives for service sector development, enhanced functionality, integrated development between manufacturing and services, improved regional layout of the service sector, and the emergence of reputable brands and leading enterprises. Well-designed and effective industrial policies, as well as calls for major breakthroughs in institutional mechanisms, must support the development of the service sector. Additionally, excessive burdens and difficult financing channels need to be addressed. More attention should be paid to the construction of the credit system, service standardization, and service statistical accounting as element tasks.
文摘The economic growth, energy structure and environmental capacity in China determine that CCS (carbon capture and storage) is an important strategic approach for China to confront the climate changes. In this paper, current status in China is firstly presented regarding policy making, technology research and development, pilot project and international cooperation. Then the opportunities of exploring CCS are analyzed from the viewpoint of application potentials, cost and China's circumstances. The challenges to CCS are pointed out with respect to energy consumption, technologies, funding and environment. Finally some suggestions are put forward on CCS development.
基金Supported by the Innovative Research Team Program by the Ministry of Education of China(IRT13070)the Nature Science Foundation of Jiangsu Province(BK2012423,BK20130925)the Opening Project of State Key Laboratory of Materials-Oriented Chemical Engineering of China(KL13-02)
文摘Photocatalytic degradation is one of the most promising remediation technologies in terms of advanced oxidation processes(AOPs) for water treatment. In this study, novel graphitic carbon nitride/titanium dioxide(gC3N4/Ti O2) composites were synthesized by a facile sonication method. The physicochemical properties of the photocatalyst with different mass ratios of g-C3N4 to Ti O2 were investigated by X-ray diffraction(XRD), scanning electron microscope(SEM), transmission electron microscopy(TEM), N2 sorption, Fourier transform infrared spectroscopy(FT-IR), X-ray photoelectron spectroscopy(XPS), and UV–vis DRS. The photocatalytic performances were evaluated by degradation of methylene blue. It was found that g-C3N4/Ti O2 with a mass ratio of 1.5:1 exhibited the best degradation performance. Under UV, the degradation rate of g-C3N4/Ti O2 was 6.92 and 2.65 times higher than g-C3N4 and Ti O2, respectively. While under visible light, the enhancement factors became 9.27(to g-C3N4) and 7.03(to Ti O2). The improved photocatalytic activity was ascribed to the interfacial charge transfer between g-C3N4 and Ti O2. This work suggests that hybridization can produce promising solar materials for environmental remediation.
基金supported financially by the Purolite Company and the Chinese National Natural Science Foundation (20674069)
文摘The performance of ion-exchange resin catalysts during isobutene (IB) dimerization was investigated under different IB contents,temperatures and liquid-volume hourly space velocity (LHSV) using a plug flow reactor in the absence of any selectivity enhancing component.High IB content and temperature resulted in a high conversion and C12 selectivity bu low C8 selectivity.The influence of LHSV was related with the IB content:LHSV had great effect at high IB content,while the performance of ion-exchange resin changed little with LHSV if IB content was low.The effect of water on the stability of resins was also studied.Desulfonation was observed during the C4 dimerization reaction when water was added to the feed.Chlorinated resin was more stable than conventional polystyrene-based resins during the test.
文摘Since the introduction of"green tyres" in the early 90's, the use of silica as a reinforcing filler, along with a silane coupling agent, has spread and grown worldwide. The greatest advantage of using silica over carbon black as reinforcing filler in a tyre tread compound is that a lower rolling resistance is achieved, while maintaining good wet traction. However, a previous study has shown that the wear resistance of a silica filled ENR (epoxidised natural rubber) compound was not as high as those of conventional OESBR (oil extended styrene butadiene rubber) and NR/BR compounds used in passenger car and truck tyre treads. In this work, with the aim of improving abrasion resistance, the effect of blending BR (butadiene rubber) into a silica filled ENR compound was studied. Blends with 0 to 30 phr BR were prepared in a Polylab Haake internal mixer. The rheological properties of the compounds were measured using a Mooney viscometer and oscillating-disc rheometer. The hardness, tensile strength and DIN abrasion resistance were also measured. The results showed that the ENR/silica compound properties such as tensile strength and hardness were as good as those of the conventional compounds. However, the most important finding was that abrasion resistance increased significantly with BR content, exceeding that of the conventional compound at BR: ENR ratios of greater than 20:80.
基金Acknowledgements This work was supported by the National Natural Science Foundation of China (Nos. 51422206 and 51372159), 1000 Talents Plan for Young Researchers, "Shuangchuang" Program of Jiangsu Province, a Project Supported by Jiangsu Science and Technology Committee for Distinguished Young Scholars (No. BK20140009), the National Basic Research Program of China (973 Program) (No. 2015CB358600) and a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD). We also acknowledge Jiangsu Nata Opto- electronic Materials Co. Ltd. for providing high purity TDMAT precursor for deposition of TiO2 thin films.
文摘Photoelectrodes with a specific structure and composition have been proposed for improving the efficiency of solar water splitting. Here, a novel multijunction structure was fabricated, with Si nanowires as cores, ZnIn2S4 nanosheets as branches, and TiO2 films as sandwiched layers. This junction exhibited a superior photoelectrochemical performance with a maximum photoconversion efficiency of 0.51%, which is 795 and 64 times higher than that of a bare Si wafer and nanowires, respectively. The large enhancement was attributed to the effective electron-hole separation and fast excited carrier transport within the multijunctions resulting from their favorable energy band alignments with water redox potentials, and to the enlarged contact area for facilitating the electron transfer at the multijunction/electrolyte interface.
文摘Near-infrared (NIR) photothermal therapy has developed very quickly in recent years. However, its clinical applications are hindered by many practical problems, such as low accumulation in tumors, high laser power density and high biotoxicity in vivo. Herein, a versatile system combining chemotherapy with photothermal therapy for cancer therapy using ultrasmall Pd nanosheets (SPNS) has been developed. The SPNS can serve as pH-responsive drug carriers to efficiently deliver DOX into cancer cells and tumors. On the other hand, the coordinative loading of DOX on SPNS enhances its accumulation in tumor tissue. So we can efficiently ablate tumor using low-intensity laser radiation. Importantly, with ultrasmall size (-4.4 nm), SPNS surface-functionalized with reduced glutathione (GSH) can be cleared from the body through the renal system into the urine. This cancer therapeutic nanosystem, which exhibits a significant synergistic effect and low systemic toxicity, has great potential for clinical applications.
文摘Supertetrahedral zinc-gallium-tin sulfide cluster modified with reduced graphene oxide protective layer was first synthesized, which exhibited an excellent photoelectrochemical performance and enhanced stability in comparison to supertetrahedral clusters.
基金This study was supported by the Project of Science and Technology Funds of Tianjin (No.06YFSZSF01200) and the National Natural Science Foundation of China (No. 30872668)
文摘Objective: To promote stem cells differentiation into neurons and enhance neuromotor function after brain injury through brain-derived neurotrophic factor (BDNF) induction. Methods: Recombinant adenovirus vector was applied to the transfection of BDNF into human-derived umbilical cord mesenchymal stem cells (UCMSCs). Enzyme linked immunosorbent assay (ELISA) was used to determine the secretion phase of BDNF. The brain injury model of athymic mice induced by hydraulic pressure percussion was established for transplantation of stem cells into the edge of injury site. Nerve function scores were obtained, and the expression level of transfected and non-transfected BDNF, proportion of neuron specific enolase (NSE) and glial fibrillary acidic protein (GFAP), and the number of apoptosis cells were compared respectively. Results: The BDNF expression achieved its stabilization at a high level 72 hours after gene transfection. The mouse obtained a better score of nerve function, and the proportion of the NSE-positive cells increased significantly (P〈0.05), but GFAP-positive cells decreased in BDNF- UCMSCs group compared with the other two groups (P〈0.05). At the site of high expression of BDNF, the number of apoptosis cells decreased markedly. Conclusion: BDNF gene can promote the differentiation of the stem cells into neurons rather than glial cells, and enhance neuromotor function after brain injury.
基金supported by the National High Technology Research and Development Program of China (Grant No. 2009AA03Z218)the National Natural Science Foundation of China (Grant No. 90923012)
文摘Al-doped ZnO (AZO) nanocrystalline aggregates (NCAs) were prepared by a low cost colloid chemistry method and effects of the Al-doped concentration on the morphological and structural properties of the AZO NCAs were studied. The dye adsorption ability of the AZO NCAs with various Al-doped concentrations was also investigated. Results indicate that the doping of the Al ions not only does not change the wurtzite structure of the ZnO crystal but also can reduce the crystallite grain size and the particle size distribution of the NCAs, which gives them a higher specific surface area and dye adsorption ability than that of the ZnO NCAs. The as-prepared AZO NCAs would be a promising material to be applied in the dye sensitized solar cells and water treatment.
文摘Visual imagery constitutes the most important sensory information for humans.The entire field of acquiring,analyzing and synthesizing visual data by means of computers is called visual computing.It has an extraordinarily wide range of applications,including for example:industrial quality control,street view and driver assistance systems,robot navigation,multimedia systems,and computer games.