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血液组分对个体化后交通动脉瘤血流特性的影响 被引量:1
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作者 吴闯 木合塔尔·克力木 +1 位作者 买买提力·艾沙 杨航 《中国组织工程研究》 CAS 北大核心 2023年第8期1219-1223,共5页
背景:血流动力学在动脉瘤的发生、发展过程中起着必不可少的作用,而对于动脉瘤的发生和破裂机制目前尚不明确。目的:分析血液组分对动脉瘤破裂的影响并探讨其作用机制。方法:采集1例52岁女性后交通动脉瘤患者的CT图像,导入到MIMICS 20.... 背景:血流动力学在动脉瘤的发生、发展过程中起着必不可少的作用,而对于动脉瘤的发生和破裂机制目前尚不明确。目的:分析血液组分对动脉瘤破裂的影响并探讨其作用机制。方法:采集1例52岁女性后交通动脉瘤患者的CT图像,导入到MIMICS 20.0中建立动脉瘤表面模型,并采用软件Geomagic Studio对模型进行处理后导出三维血管壁模型。将血液分别假定为单相流和两相流,采用计算流体力学的方法对动脉瘤以及载瘤动脉内的血流进行数值模拟,分析血液流线流速、壁面的形变位移、壁面切应力以及血液相对血管壁停滞时间等血流动力学参数的变化。结果和结论:①在相同时刻,两种模型内的血液流态基本保持一致,两相流模型与单相流模型相比较具有更高的低壁面剪切应力面积占比,具有更大的形变位移以及血液相对血管壁的高相对停滞时间面积占比更大;②与单相流模型相比,两相流模型更易使血管壁内皮细胞受损,导致结构与功能异常;③两相流模型更易形成血栓,造成血栓脱落导致载瘤动脉瘤的阻塞;④结果表明,两相流模型具有更大的位移,即所受应力更大,在该条件下动脉瘤更易产生破裂。 展开更多
关键词 流-固耦合 两相流 壁面剪切应力 相对停滞时间 血液组分 入口条件 三维模型 壁面位移 动脉瘤
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An integrated approach to study of strata behaviour and gas flow dynamics and its application 被引量:30
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作者 Hua Guo Liang Yuan 《International Journal of Coal Science & Technology》 EI 2015年第1期12-21,共10页
This paper presents an advanced and integrated research approach to longwall mining-induced strata move- ment, stress changes, fractures, and gas flow dynamics with actual examples of its application from recent studi... This paper presents an advanced and integrated research approach to longwall mining-induced strata move- ment, stress changes, fractures, and gas flow dynamics with actual examples of its application from recent studies for coextraction of coal and methane development at Huainan Mining Group in China, in a deep and multi-seam mining environment. The advanced approach takes advantage of the latest techniques in Australia for mine scale geotechnical characterisation, field measurement, monitoring and numerical modelling. Key techniques described in this paper include coal mine site 3D geotechnical characterisation methods, surface deep downhole multi-point extensometers and piezometers for overburden displacement and pore pressure measurements during mining, tracer gas tests for goal gas flow patterns, and advanced numerical modelling codes for coupled coal mine strata, water and gas simulations, and longwall goaf gas ttow investigations. This integrated approach has resulted in significant insights into the complex dynamic imeraction between strata, groundwater, and gas during mining at Huainan Mining Group in recent years. Based on the lindings from the extensive field monitoring and numerical modelling studies, a three-dimensional annular-shaped over-lying zone along the perimeter of the longwall panel was identified for optimal methane drainage during mining. 展开更多
关键词 Co-extraction of coal and gas Strata behaviour Pore pressure Gas flow Annular overlying zone COSFLOW CFD
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