Primary liver cancer is the fifth most common malignancy in men and the eighth in women worldwide. The liver is also the second most common site for metastatic spread of cancer. To assist in the diagnosis of these liv...Primary liver cancer is the fifth most common malignancy in men and the eighth in women worldwide. The liver is also the second most common site for metastatic spread of cancer. To assist in the diagnosis of these liver lesions non-invasive advanced imaging techniques are desirable. Magnetic resonance (MR) is commonly used to identify anatomical lesions, but it is a very versatile technique and also can provide specific information on tumor pathophysiology and metabolism, in particular with the application of MR spectroscopy (MRS). This may include data on the type, grade and stage of tumors, and thus assist in further management of the disease. The purpose of this review is to summarize and discuss the available literature on proton, phosphorus and carbon-13-MRS as performed on primary liver tumors and metastases, with human applications as the main perspective. Upcoming MRSapproaches with potential applications to liver tumors are also included. Since knowledge of some technical background is indispensable to understand the results, a basic introduction of MRS and some technical issues of MRS as applied to tumors and metastases in the liver are described as well. In vivo MR spectroscopy of tumors in a metabolically active organ such as the liver has been demonstrated to provide important information on tumor metabolism, but it also is challenging as compared to applications on some other tissues, in particular in humans, mostly because of its abdominal location where movement may be a disturbing factor.展开更多
The present paper reviews new findings in redoxproperties of the active constituent of Chinese herbalmedicine(CHM),a kind of CHM or a compoundprescription as an antioxidant.Firstly,we have studiedtheir antioxidant and...The present paper reviews new findings in redoxproperties of the active constituent of Chinese herbalmedicine(CHM),a kind of CHM or a compoundprescription as an antioxidant.Firstly,we have studiedtheir antioxidant and prooxidant actions with electronspin resonance(ESR).The results show that the activecomponents from over 10 kinds of CHM are able toscavenge the oxygen free radicals but propyl gallate展开更多
It is interesting to maximize the amount of information we can obtain from one experiment on a single sample. In obtaining all the thermodynamic properties of some materials from their experimental heat capacity data ...It is interesting to maximize the amount of information we can obtain from one experiment on a single sample. In obtaining all the thermodynamic properties of some materials from their experimental heat capacity data only, we aim to get the tempera- ture-independent energy spectrum. However, all the practical measured energy spectra depend on the temperature of experi- ments. One promising method to obtain the temperature-independent energy spectrum is to solve the so-called specific heat-phonon spectrum inversion （SPI） problem. Here we show, by developing a new practical solution method of SPI, the phonon spectrum of the negative thermal expansion material ZrW208 is obtained. This phonon spectrum is tempera- ture-independent and almost method independent. Hence all the thermodynamic properties of ZrW208, such as thermodynamic potential, entropy, Helmholtz free energy, etc. are obtained by heat capacity only.展开更多
基金Supported by A grant from the Dutch Cancer Society (KWF Kankerbestrijding), No. KUN 2008-4098
文摘Primary liver cancer is the fifth most common malignancy in men and the eighth in women worldwide. The liver is also the second most common site for metastatic spread of cancer. To assist in the diagnosis of these liver lesions non-invasive advanced imaging techniques are desirable. Magnetic resonance (MR) is commonly used to identify anatomical lesions, but it is a very versatile technique and also can provide specific information on tumor pathophysiology and metabolism, in particular with the application of MR spectroscopy (MRS). This may include data on the type, grade and stage of tumors, and thus assist in further management of the disease. The purpose of this review is to summarize and discuss the available literature on proton, phosphorus and carbon-13-MRS as performed on primary liver tumors and metastases, with human applications as the main perspective. Upcoming MRSapproaches with potential applications to liver tumors are also included. Since knowledge of some technical background is indispensable to understand the results, a basic introduction of MRS and some technical issues of MRS as applied to tumors and metastases in the liver are described as well. In vivo MR spectroscopy of tumors in a metabolically active organ such as the liver has been demonstrated to provide important information on tumor metabolism, but it also is challenging as compared to applications on some other tissues, in particular in humans, mostly because of its abdominal location where movement may be a disturbing factor.
文摘The present paper reviews new findings in redoxproperties of the active constituent of Chinese herbalmedicine(CHM),a kind of CHM or a compoundprescription as an antioxidant.Firstly,we have studiedtheir antioxidant and prooxidant actions with electronspin resonance(ESR).The results show that the activecomponents from over 10 kinds of CHM are able toscavenge the oxygen free radicals but propyl gallate
基金supported by the National Natural Science Foundation of China (Grant Nos. 10675031,10375012 and 19975009)the Department of Education of Zhejiang Province (Grant No. Y200906911)
文摘It is interesting to maximize the amount of information we can obtain from one experiment on a single sample. In obtaining all the thermodynamic properties of some materials from their experimental heat capacity data only, we aim to get the tempera- ture-independent energy spectrum. However, all the practical measured energy spectra depend on the temperature of experi- ments. One promising method to obtain the temperature-independent energy spectrum is to solve the so-called specific heat-phonon spectrum inversion （SPI） problem. Here we show, by developing a new practical solution method of SPI, the phonon spectrum of the negative thermal expansion material ZrW208 is obtained. This phonon spectrum is tempera- ture-independent and almost method independent. Hence all the thermodynamic properties of ZrW208, such as thermodynamic potential, entropy, Helmholtz free energy, etc. are obtained by heat capacity only.
