目的制定声带器质性发声障碍患者围手术期嗓音康复审查指标,分析障碍因素,为证据的临床转化提供依据。方法以知识转化模式(knowledge to action framework,KTA)为理论指导,按照知识应用步骤:确定问题,组建循证小组和专家团队;将知识引...目的制定声带器质性发声障碍患者围手术期嗓音康复审查指标,分析障碍因素,为证据的临床转化提供依据。方法以知识转化模式(knowledge to action framework,KTA)为理论指导,按照知识应用步骤:确定问题,组建循证小组和专家团队;将知识引入临床情景,综合函询和讨论制定审查指标及审查方法;根据基线审查结果基于渥太华研究应用模型(Ottawa Model of Research Use,OMRU),经头脑风暴法分析证据引入临床的障碍因素。结果共纳入15条最佳证据,制定13条审查指标及其方法;归纳分析出3方面的8条障碍因素,即基于证据变革方面2条、潜在采纳者3条及实践环境3条。结论本研究审查指标制定具有科学性和内容可行性,障碍因素评估具有科学性和内容新颖性,研究方法有借鉴作用,研究内容为证据转化提供依据。展开更多
The extended two-mass model is adopted to analyze the nonlinear oscillation of pathological vocal folds during vocalization. Redundant tissue or area in laryngeal patients is modeled as a massless rigid connected to t...The extended two-mass model is adopted to analyze the nonlinear oscillation of pathological vocal folds during vocalization. Redundant tissue or area in laryngeal patients is modeled as a massless rigid connected to the upper mass of the vocal folds, and a parameter Q is introduced to represent the change of glottal configurations and tension imbalance between the left and right sides of vocal folds. Numerical simulations demonstrate that the pathological vocal-fold decreases the threshold of Q to generate nonlinear vocal oscillation, indicating the improvement of the sensitivity of vocal folds to asymmetries and enhancing the coupling between two sides. Furthermore, the pathological vocal-fold can lower the fundamental frequency and eliminate high-order harmonics, For example, the fundamental frequency decreases from 119.94 Hz to 84.95 Hz when Q=0.58 and the sub-glottal pressure 1450 Pa. However, there are no prominent effects on the amplitudes of sub-harmonic and low-order harmonics.展开更多
文摘目的制定声带器质性发声障碍患者围手术期嗓音康复审查指标,分析障碍因素,为证据的临床转化提供依据。方法以知识转化模式(knowledge to action framework,KTA)为理论指导,按照知识应用步骤:确定问题,组建循证小组和专家团队;将知识引入临床情景,综合函询和讨论制定审查指标及审查方法;根据基线审查结果基于渥太华研究应用模型(Ottawa Model of Research Use,OMRU),经头脑风暴法分析证据引入临床的障碍因素。结果共纳入15条最佳证据,制定13条审查指标及其方法;归纳分析出3方面的8条障碍因素,即基于证据变革方面2条、潜在采纳者3条及实践环境3条。结论本研究审查指标制定具有科学性和内容可行性,障碍因素评估具有科学性和内容新颖性,研究方法有借鉴作用,研究内容为证据转化提供依据。
基金supported by the National Basic Research Program of China(Grant No. 2011CB707900)the National Natural Science Foundation of China(Grant Nos. 81127901, 11174141 and 11161120324)the State Key Laboratory of Acoustics, Chinese Academy of Sciences
文摘The extended two-mass model is adopted to analyze the nonlinear oscillation of pathological vocal folds during vocalization. Redundant tissue or area in laryngeal patients is modeled as a massless rigid connected to the upper mass of the vocal folds, and a parameter Q is introduced to represent the change of glottal configurations and tension imbalance between the left and right sides of vocal folds. Numerical simulations demonstrate that the pathological vocal-fold decreases the threshold of Q to generate nonlinear vocal oscillation, indicating the improvement of the sensitivity of vocal folds to asymmetries and enhancing the coupling between two sides. Furthermore, the pathological vocal-fold can lower the fundamental frequency and eliminate high-order harmonics, For example, the fundamental frequency decreases from 119.94 Hz to 84.95 Hz when Q=0.58 and the sub-glottal pressure 1450 Pa. However, there are no prominent effects on the amplitudes of sub-harmonic and low-order harmonics.
