Primary and metastatic liver tumors are an increasing global health problem,with hepatocellular carcinoma(HCC)now being the third leading cause of cancer-related mortality worldwide.Systemic treatment options for HCC ...Primary and metastatic liver tumors are an increasing global health problem,with hepatocellular carcinoma(HCC)now being the third leading cause of cancer-related mortality worldwide.Systemic treatment options for HCC remain limited,with Sorafenib as the only prospectively validated agent shown to increase overall survival.Surgical resection and/or transplantation,locally ablative therapies and regional or locoregional therapies have filled the gap in liver tumor treatments,providing improved survival outcomes for both primary and metastatic tumors.Minimally invasive local therapies have an increasing role in the treatment of both primary and metastatic liver tumors.For patients with low volume disease,these therapies have now been established into consensus practice guidelines.This review highlights technical aspects and outcomes of commonly utilized,minimally invasive local therapies including laparoscopic liver resection(LLR),radiofrequency ablation(RFA),microwave ablation(MWA),high-intensity focused ultrasound(HIFU),irreversible electroporation(IRE),and stereotactic body radiation therapy(SBRT).In addition,the role of combination treatment strategies utilizing these minimally invasive techniques is reviewed.展开更多
AIM: To prospectively evaluate the usefulness of a pattern-based classification of contrast-enhanced sonographic findings for differential diagnosis of hepatic tumors. METHODS: We evaluated the enhancement pattern of ...AIM: To prospectively evaluate the usefulness of a pattern-based classification of contrast-enhanced sonographic findings for differential diagnosis of hepatic tumors. METHODS: We evaluated the enhancement pattern of the contrast-enhanced sonography images in 586 patients with 586 hepatic lesions, consisting of 383 hepatocellular carcinomas, 89 metastases, and 114 hemangiomas. After injecting a galactose-palmitic acid contrast agent, lesions were scanned by contrast- enhanced harmonic gray-scale sonography in three phases: arterial, portal, and late. The enhancement patterns of the initial 303 lesions were classified retrospectively, and multiple logistic regression analysis was used to identify enhancement patterns that allowed differentiation between hepatic tumors. We then used the pattern-based classification of enhancement we had retrospectively devised to prospectively diagnose 283 liver tumors. RESULTS: Seven enhancement patterns were found to be significant predictors of different hepatic tumors. The presence of homogeneous or heterogeneous enhancement both in the arterial and portal phase was the typical enhancement pattern for hepatocellular carcinoma, while the presence of peritumoral vessels in the arterial phase and ring enhancement or a perfusion defect in the portal phase was the typical enhancement pattern for metastases, and the presence of peripheral nodular enhancement both in the arterial and portal phase was the typical enhancement pattern forhemangioma. The sensitivity, specificity, and accuracy of prospective diagnosis based on the combinations of enhancement patterns, respectively, were 93.2%, 96.2%, and 94.0% for hepatocellular carcinoma, 87.9%, 99.6%, and 98.2% for metastasis, and 95.6%, 94.1%, and 94.3% for hemangioma. CONCLUSION: The pattern-based classification of the contrast-enhanced sonographic findings is useful for differentiating among hepatic tumors.展开更多
Non-equilibrium molecular dynamics simulations have been performed to investigate the effect of the cross-section shape on the thermal conductivity of argon nanowires. Some typical cross-section shapes, such as triang...Non-equilibrium molecular dynamics simulations have been performed to investigate the effect of the cross-section shape on the thermal conductivity of argon nanowires. Some typical cross-section shapes, such as triangle, square, pentagon, hexagon and circle, axe carefully explored. The simulation results show that with the same cross-sectional area of the regular polygons, tim thermal conductivities decrease with the reduction of the sides of the polygons, and the thermal conductivity of the circular nanowire is larger than those of the other polygonal ones. Phonon gas kinetic theory is used to analyse the phonon transport in nanowires, and the concept of equivalent diameter is proposed to illustrate the characteristic dimension of the none-circulax cross-section.展开更多
In order to improve image quality, a novel Retinex algorithm for image enhancement was presented. Different from conventional algorithms, it was based on certain defined points containing the illumination information ...In order to improve image quality, a novel Retinex algorithm for image enhancement was presented. Different from conventional algorithms, it was based on certain defined points containing the illumination information in the intensity image to estimate the illumination. After locating the points, the whole illumination image was computed by an interpolation technique. When attempting to recover the reflectance image, an adaptive method which can be considered as an optimization problem was employed to suppress noise in dark environments and keep details in other areas. For color images, it was taken in the band of each channel separately. Experimental results demonstrate that the proposed algorithm is superior to the traditional Retinex algorithms in image entropy.展开更多
A novel algorithm for voice conversion is proposed in this paper. The mapping function of spectral vectors of the source and target speakers is calculated by the Canonical Correlation Analysis (CCA) estimation based o...A novel algorithm for voice conversion is proposed in this paper. The mapping function of spectral vectors of the source and target speakers is calculated by the Canonical Correlation Analysis (CCA) estimation based on Gaussian mixture models. Since the spectral envelope feature remains a majority of second order statistical information contained in speech after Linear Prediction Coding (LPC) analysis, the CCA method is more suitable for spectral conversion than Minimum Mean Square Error (MMSE) because CCA explicitly considers the variance of each component of the spectral vectors during conversion procedure. Both objective evaluations and subjective listening tests are conducted. The experimental results demonstrate that the proposed scheme can achieve better per- formance than the previous method which uses MMSE estimation criterion.展开更多
An algorithm was proposed to fast recognize three types of underwater micro-terrain, i.e. the level, the gradient and the uneven. With pendulum single beam bathymeter, the hard level concrete floor, the random uneven ...An algorithm was proposed to fast recognize three types of underwater micro-terrain, i.e. the level, the gradient and the uneven. With pendulum single beam bathymeter, the hard level concrete floor, the random uneven floor and the gradient wood panel (8-) were ultrasonically detected 20 times, respectively. The results show that the algorithm is right from fact that the first clustering values of the uneven are all less than the threshold value of 60.0% that is obtained by the level and gradient samples. The algorithm based on the dynamic clustering theory can effectively eliminate the influences of the exceptional elevation values produced by the disturbances resulted from the grazing angle, the characteristic of bottom material and environmental noises, and its real-time capability is good. Thus, the algorithm provides a foundation for the next restructuring of the micro-terrain.展开更多
This paper carries out tbe experirnent study on the correlation between am stress-strain process of rock samples and the acoustie parameter change of rock by using the measurement system of KS acoustic wave data proce...This paper carries out tbe experirnent study on the correlation between am stress-strain process of rock samples and the acoustie parameter change of rock by using the measurement system of KS acoustic wave data processing device. On the spot, the stability of surrounding rock is studied by means of experiments on the relationship between the change process (from elastie to plastic failure zone) in surrounding rock of roadway and the change law of acoustic parameters of rock. These acoustie parameters inelude wave amplitude, spectral amplitude, spectrum area, spectral density,wave veloeity and attenuation coefficient etc.展开更多
The Magnetic Barkhausen Noise （MBN） technology is a non-destructive method to measure the neutral temperature of thc CWR track. A series of in-field verifications and data comparison on Australian mainline tracks ha...The Magnetic Barkhausen Noise （MBN） technology is a non-destructive method to measure the neutral temperature of thc CWR track. A series of in-field verifications and data comparison on Australian mainline tracks have shown the results from that system are highly accurate and reliable. The system can be an accuracy and cost-effective tool to prevent the potential buckling and break of CWR rails. The physical backgrounds and features of the system are represented in this paper. The Darwin-Alice Springs Line is a newly constructed main line in Australia which is linked from the north and middle of Australia. Originally, this rail line is designed and constructed in a ＂cost-effective＂ way to a lower price, and the key parameters are relatively low. To maintain the stability of the CWR tracks in a very harsh environment, some new technologies such as the MBN technology were utilised. From the results of neutral temperature, it is found that the majority of them are very high. Combined with the calculation and finite element analysis, these problems evidenced that it is caused by the low toe load fastening system and high sleeper spacing. After that some suggestions are given to improve the stability of the CWR on the railway line.展开更多
文摘Primary and metastatic liver tumors are an increasing global health problem,with hepatocellular carcinoma(HCC)now being the third leading cause of cancer-related mortality worldwide.Systemic treatment options for HCC remain limited,with Sorafenib as the only prospectively validated agent shown to increase overall survival.Surgical resection and/or transplantation,locally ablative therapies and regional or locoregional therapies have filled the gap in liver tumor treatments,providing improved survival outcomes for both primary and metastatic tumors.Minimally invasive local therapies have an increasing role in the treatment of both primary and metastatic liver tumors.For patients with low volume disease,these therapies have now been established into consensus practice guidelines.This review highlights technical aspects and outcomes of commonly utilized,minimally invasive local therapies including laparoscopic liver resection(LLR),radiofrequency ablation(RFA),microwave ablation(MWA),high-intensity focused ultrasound(HIFU),irreversible electroporation(IRE),and stereotactic body radiation therapy(SBRT).In addition,the role of combination treatment strategies utilizing these minimally invasive techniques is reviewed.
文摘AIM: To prospectively evaluate the usefulness of a pattern-based classification of contrast-enhanced sonographic findings for differential diagnosis of hepatic tumors. METHODS: We evaluated the enhancement pattern of the contrast-enhanced sonography images in 586 patients with 586 hepatic lesions, consisting of 383 hepatocellular carcinomas, 89 metastases, and 114 hemangiomas. After injecting a galactose-palmitic acid contrast agent, lesions were scanned by contrast- enhanced harmonic gray-scale sonography in three phases: arterial, portal, and late. The enhancement patterns of the initial 303 lesions were classified retrospectively, and multiple logistic regression analysis was used to identify enhancement patterns that allowed differentiation between hepatic tumors. We then used the pattern-based classification of enhancement we had retrospectively devised to prospectively diagnose 283 liver tumors. RESULTS: Seven enhancement patterns were found to be significant predictors of different hepatic tumors. The presence of homogeneous or heterogeneous enhancement both in the arterial and portal phase was the typical enhancement pattern for hepatocellular carcinoma, while the presence of peritumoral vessels in the arterial phase and ring enhancement or a perfusion defect in the portal phase was the typical enhancement pattern for metastases, and the presence of peripheral nodular enhancement both in the arterial and portal phase was the typical enhancement pattern forhemangioma. The sensitivity, specificity, and accuracy of prospective diagnosis based on the combinations of enhancement patterns, respectively, were 93.2%, 96.2%, and 94.0% for hepatocellular carcinoma, 87.9%, 99.6%, and 98.2% for metastasis, and 95.6%, 94.1%, and 94.3% for hemangioma. CONCLUSION: The pattern-based classification of the contrast-enhanced sonographic findings is useful for differentiating among hepatic tumors.
文摘Non-equilibrium molecular dynamics simulations have been performed to investigate the effect of the cross-section shape on the thermal conductivity of argon nanowires. Some typical cross-section shapes, such as triangle, square, pentagon, hexagon and circle, axe carefully explored. The simulation results show that with the same cross-sectional area of the regular polygons, tim thermal conductivities decrease with the reduction of the sides of the polygons, and the thermal conductivity of the circular nanowire is larger than those of the other polygonal ones. Phonon gas kinetic theory is used to analyse the phonon transport in nanowires, and the concept of equivalent diameter is proposed to illustrate the characteristic dimension of the none-circulax cross-section.
基金Project(61071162) supported by the National Natural Science Foundation of China
文摘In order to improve image quality, a novel Retinex algorithm for image enhancement was presented. Different from conventional algorithms, it was based on certain defined points containing the illumination information in the intensity image to estimate the illumination. After locating the points, the whole illumination image was computed by an interpolation technique. When attempting to recover the reflectance image, an adaptive method which can be considered as an optimization problem was employed to suppress noise in dark environments and keep details in other areas. For color images, it was taken in the band of each channel separately. Experimental results demonstrate that the proposed algorithm is superior to the traditional Retinex algorithms in image entropy.
文摘A novel algorithm for voice conversion is proposed in this paper. The mapping function of spectral vectors of the source and target speakers is calculated by the Canonical Correlation Analysis (CCA) estimation based on Gaussian mixture models. Since the spectral envelope feature remains a majority of second order statistical information contained in speech after Linear Prediction Coding (LPC) analysis, the CCA method is more suitable for spectral conversion than Minimum Mean Square Error (MMSE) because CCA explicitly considers the variance of each component of the spectral vectors during conversion procedure. Both objective evaluations and subjective listening tests are conducted. The experimental results demonstrate that the proposed scheme can achieve better per- formance than the previous method which uses MMSE estimation criterion.
基金Project(50474052) supported by the National Natural Foundation of China
文摘An algorithm was proposed to fast recognize three types of underwater micro-terrain, i.e. the level, the gradient and the uneven. With pendulum single beam bathymeter, the hard level concrete floor, the random uneven floor and the gradient wood panel (8-) were ultrasonically detected 20 times, respectively. The results show that the algorithm is right from fact that the first clustering values of the uneven are all less than the threshold value of 60.0% that is obtained by the level and gradient samples. The algorithm based on the dynamic clustering theory can effectively eliminate the influences of the exceptional elevation values produced by the disturbances resulted from the grazing angle, the characteristic of bottom material and environmental noises, and its real-time capability is good. Thus, the algorithm provides a foundation for the next restructuring of the micro-terrain.
文摘This paper carries out tbe experirnent study on the correlation between am stress-strain process of rock samples and the acoustie parameter change of rock by using the measurement system of KS acoustic wave data processing device. On the spot, the stability of surrounding rock is studied by means of experiments on the relationship between the change process (from elastie to plastic failure zone) in surrounding rock of roadway and the change law of acoustic parameters of rock. These acoustie parameters inelude wave amplitude, spectral amplitude, spectrum area, spectral density,wave veloeity and attenuation coefficient etc.
文摘The Magnetic Barkhausen Noise （MBN） technology is a non-destructive method to measure the neutral temperature of thc CWR track. A series of in-field verifications and data comparison on Australian mainline tracks have shown the results from that system are highly accurate and reliable. The system can be an accuracy and cost-effective tool to prevent the potential buckling and break of CWR rails. The physical backgrounds and features of the system are represented in this paper. The Darwin-Alice Springs Line is a newly constructed main line in Australia which is linked from the north and middle of Australia. Originally, this rail line is designed and constructed in a ＂cost-effective＂ way to a lower price, and the key parameters are relatively low. To maintain the stability of the CWR tracks in a very harsh environment, some new technologies such as the MBN technology were utilised. From the results of neutral temperature, it is found that the majority of them are very high. Combined with the calculation and finite element analysis, these problems evidenced that it is caused by the low toe load fastening system and high sleeper spacing. After that some suggestions are given to improve the stability of the CWR on the railway line.
