OBJECTIVE: We sought to estimate the rates and types of evaluation in women with atypical glandular cells of undetermined significance (AGC-US) on cervical cytology and to assess these findings on the basis of publish...OBJECTIVE: We sought to estimate the rates and types of evaluation in women with atypical glandular cells of undetermined significance (AGC-US) on cervical cytology and to assess these findings on the basis of published management guidelines. METHODS: The rates of histologic sampling, comprehensive initial evaluations, and secondary evaluations were assessed in 477 women with an AGC-US Pap test from 1998 to 2001. A comprehensive evaluation was defined as a colposcopy and an endocervical curettage with or without a cervical biopsy. For women aged 35 or older, a comprehensive evaluation also included an endometrial biopsy. A secondary evaluation consisted of a diagnostic cone biopsy. RESULTS: Sixty-four percent of women with an AGC-US Pap test had histologic sampling; 36%were followed by repeat Pap test only. Thirty-six percent of women with an AGC-US Pap test had a comprehensive evaluation. Women with an AGC-US Pap test that was subclassified as malignant-appearing had higher rates of histologic and comprehensive evaluations than women with a benign-appearing or unspecified AGC-US Pap test (P < .01). Twenty-eight percent of women aged 35 or older had comprehensive evaluations compared with 57%of women younger than the age of 35 (P < .01). Secondary evaluations were performed in 8%of women with persistent AGC-US Pap tests and 2%of women with malignant-appearing AGC-US Pap tests after negative initial histologic evaluations. Twelve of the 42 cases of disease (29%) were diagnosed more than 1 year from the initial AGC-US Pap test. CONCLUSION: On the basis of accepted management guidelines, these data suggest that women with AGC-US Pap tests are under-managed in both their initial and secondary evaluations.展开更多
In the present paper, the authors expound the approaches of four-gate points on treatment of diseases and the relevant theoretic evidence. The analysis and discussion were carried on in the aspects of the origins of f...In the present paper, the authors expound the approaches of four-gate points on treatment of diseases and the relevant theoretic evidence. The analysis and discussion were carried on in the aspects of the origins of four-gate points and the relationships of four-gate points with primary qi, running course of meridian, qi and blood and biaoben qijie of meridian and collateral. Being the major points in clinic, four-gate points provide extensive indications and good therapeutic effects, which are supported thoroughly by the theoretic evidence.展开更多
文摘OBJECTIVE: We sought to estimate the rates and types of evaluation in women with atypical glandular cells of undetermined significance (AGC-US) on cervical cytology and to assess these findings on the basis of published management guidelines. METHODS: The rates of histologic sampling, comprehensive initial evaluations, and secondary evaluations were assessed in 477 women with an AGC-US Pap test from 1998 to 2001. A comprehensive evaluation was defined as a colposcopy and an endocervical curettage with or without a cervical biopsy. For women aged 35 or older, a comprehensive evaluation also included an endometrial biopsy. A secondary evaluation consisted of a diagnostic cone biopsy. RESULTS: Sixty-four percent of women with an AGC-US Pap test had histologic sampling; 36%were followed by repeat Pap test only. Thirty-six percent of women with an AGC-US Pap test had a comprehensive evaluation. Women with an AGC-US Pap test that was subclassified as malignant-appearing had higher rates of histologic and comprehensive evaluations than women with a benign-appearing or unspecified AGC-US Pap test (P < .01). Twenty-eight percent of women aged 35 or older had comprehensive evaluations compared with 57%of women younger than the age of 35 (P < .01). Secondary evaluations were performed in 8%of women with persistent AGC-US Pap tests and 2%of women with malignant-appearing AGC-US Pap tests after negative initial histologic evaluations. Twelve of the 42 cases of disease (29%) were diagnosed more than 1 year from the initial AGC-US Pap test. CONCLUSION: On the basis of accepted management guidelines, these data suggest that women with AGC-US Pap tests are under-managed in both their initial and secondary evaluations.
基金The study is subsidized by Specific Clinical Research on Chinese Medicine of Sciences and Technology, China Administration of Chinese Medicine(04-05LQ05)
文摘In the present paper, the authors expound the approaches of four-gate points on treatment of diseases and the relevant theoretic evidence. The analysis and discussion were carried on in the aspects of the origins of four-gate points and the relationships of four-gate points with primary qi, running course of meridian, qi and blood and biaoben qijie of meridian and collateral. Being the major points in clinic, four-gate points provide extensive indications and good therapeutic effects, which are supported thoroughly by the theoretic evidence.
