评价对照组和治疗组两种不同治疗方案对儿童肾小球肾炎的疗效。方法 选择符合纳入标准的患儿各30例,分为对照组和治疗组。对照组给予常规治疗,治疗组在常规治疗基础上联合应用新辅助治疗。比较两组治疗效果、症状缓解时间、尿常规恢复...评价对照组和治疗组两种不同治疗方案对儿童肾小球肾炎的疗效。方法 选择符合纳入标准的患儿各30例,分为对照组和治疗组。对照组给予常规治疗,治疗组在常规治疗基础上联合应用新辅助治疗。比较两组治疗效果、症状缓解时间、尿常规恢复时间、复发率及不良反应发生率。结果 治疗组总有效率明显高于对照组(96.67% vs 80.00%,P<0.05)。治疗组症状缓解时间、尿常规恢复正常时间均短于对照组(P<0.05)。治疗组复发率显著低于对照组(3.33% vs 23.33%,P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 该新辅助治疗方案能显著提高儿童肾小球肾炎的疗效,缩短症状缓解时间,降低复发率,值得临床推广应用。在复发性尿道感染的临床治疗中,以中西医结合的方式进行治疗,可提高治疗效果,有利于患者症状表现尽快好转,降低复发率,且不良反应少,推荐临床应用。展开更多
Objective: This study examined Herpes Simplex Virus (HSV) subclinical shedding in the genital tract of patients withgenital herpes (GH) or non-gonoccal urethritis (NGU). Method Swabs were collected after exposure to r...Objective: This study examined Herpes Simplex Virus (HSV) subclinical shedding in the genital tract of patients withgenital herpes (GH) or non-gonoccal urethritis (NGU). Method Swabs were collected after exposure to rash andgenital tract during GH relapse or remission on a weekly basisfor four to six weeks. NGU patients with negative chlamydiaand mycoplasma tests were also swabbed for a similarduration. All swabs underwent HSV DNA detection withquantitative PCR. Result: There was a significant difference in the rate ofasymptomatic HSV shedding in urinary tracts comparing GHand the control group and comparing NGU and the controlgroup (P<0.05). The rate of HSV shedding was 22%, 9.8%and 3.3% for GH, NGU and control groups respectively. Therate of HSV shedding was 21.7% (20/92) for patients withactive GH and 23% for those in remission. The HSV positiverate was significantly higher in the group with patients whohad more than six relapses within one year compared to thegroup of patients with less than six relapses.Conclusion: There is HSV subclinical shedding in theirgenital tract during active GH and remission. SubclinicalHSV shedding is more common in patients with more than sixGH relapses per year compared to GH patients with fewerrelapses. Approximately 9.9% of NGU patients with negativechlamydia mycoplasma testing was found to have subclinicalHSV infection.展开更多
文摘评价对照组和治疗组两种不同治疗方案对儿童肾小球肾炎的疗效。方法 选择符合纳入标准的患儿各30例,分为对照组和治疗组。对照组给予常规治疗,治疗组在常规治疗基础上联合应用新辅助治疗。比较两组治疗效果、症状缓解时间、尿常规恢复时间、复发率及不良反应发生率。结果 治疗组总有效率明显高于对照组(96.67% vs 80.00%,P<0.05)。治疗组症状缓解时间、尿常规恢复正常时间均短于对照组(P<0.05)。治疗组复发率显著低于对照组(3.33% vs 23.33%,P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 该新辅助治疗方案能显著提高儿童肾小球肾炎的疗效,缩短症状缓解时间,降低复发率,值得临床推广应用。在复发性尿道感染的临床治疗中,以中西医结合的方式进行治疗,可提高治疗效果,有利于患者症状表现尽快好转,降低复发率,且不良反应少,推荐临床应用。
基金This Project was supported by Medical and Health Care Scientific Research Fund of Guangdong Province(B1998147).
文摘Objective: This study examined Herpes Simplex Virus (HSV) subclinical shedding in the genital tract of patients withgenital herpes (GH) or non-gonoccal urethritis (NGU). Method Swabs were collected after exposure to rash andgenital tract during GH relapse or remission on a weekly basisfor four to six weeks. NGU patients with negative chlamydiaand mycoplasma tests were also swabbed for a similarduration. All swabs underwent HSV DNA detection withquantitative PCR. Result: There was a significant difference in the rate ofasymptomatic HSV shedding in urinary tracts comparing GHand the control group and comparing NGU and the controlgroup (P<0.05). The rate of HSV shedding was 22%, 9.8%and 3.3% for GH, NGU and control groups respectively. Therate of HSV shedding was 21.7% (20/92) for patients withactive GH and 23% for those in remission. The HSV positiverate was significantly higher in the group with patients whohad more than six relapses within one year compared to thegroup of patients with less than six relapses.Conclusion: There is HSV subclinical shedding in theirgenital tract during active GH and remission. SubclinicalHSV shedding is more common in patients with more than sixGH relapses per year compared to GH patients with fewerrelapses. Approximately 9.9% of NGU patients with negativechlamydia mycoplasma testing was found to have subclinicalHSV infection.
