The distribution of stress and strain between adjacent particles in particulate reinforced metal matrix composites wasinvestigated using cohesive zone models. It is found that the strain of the composite is concentrat...The distribution of stress and strain between adjacent particles in particulate reinforced metal matrix composites wasinvestigated using cohesive zone models. It is found that the strain of the composite is concentrated in the matrix, and there is aregion with higher strain along the loading path, which can promote the formation of a void near the particles pole. The stress andstrain in matrix near the particles gradually decrease with the increase of the distance between particles. And it is calculated that thereis a critical distance within which the stress and strain fields of the neighboring particles can influence with each other. This criticaldistance increases with the increase of particle size. It is also found that the angle between the tensile direction and the center line ofparticles plays an important role in the stress and strain distribution. The model with the angle of 0° has the greatest influence on thedistribution of stress and strain in the matrix, while the model with the angle of 45° has the least influence on the distribution of stressand strain in the matrix.展开更多
Flaviviral NS2B is a required cofactor for NS3 serine protease activity and plays an important role in promoting functional NS2B-NS3 protease configuration and maintaining critical interactions with protease catalysis...Flaviviral NS2B is a required cofactor for NS3 serine protease activity and plays an important role in promoting functional NS2B-NS3 protease configuration and maintaining critical interactions with protease catalysis substrates. The residues D80DDG in West Nile virus (WNV) NS2B are important for protease activity. To investigate the effects of D80DDG in NS2B on protease activity and viral replication, the negatively charged region D80DD and the conserved residue G83 of NS2B were mutated (D80DD/E80EE, D80DD/K80KK, D80DD/A80AA, G83F, G83S, G83D, G83K, and G83A), and NS3 D75A was designated as the negative control. The effects of the mutations on NS2B-NS3 activity, viral translation, and viral RNA replication were analyzed using kinetic analysis of site-directed enzymes and a transient replicon assay. All substitutions resulted in significantly decreased enzyme activity and blocked RNA replication. The negative charge of D80DD is not important for maintaining NS2B function, but side chain changes in G83 have dramatic effects on protease activity and RNA replication. These results demonstrate that NS2B is important for viral replication and that D80DD and G83 substitutions prevent replication; they will be useful for understanding the relationship between NS2B and NS3.展开更多
In this study,the effect of influencing parameters on the stress distribution around a polygonal cutout within a laminated composite under uniform heat flux was analytically examined.The analytical method was develope...In this study,the effect of influencing parameters on the stress distribution around a polygonal cutout within a laminated composite under uniform heat flux was analytically examined.The analytical method was developed based on the classical laminated plate theory and two-dimensional thermo-elastic method.A mapping function was employed to extend the solution of a perforated symmetric laminate with a circular cutout to the solution of polygonal cutouts.The effect of significant parameters such as the cutout angular position,bluntness and aspect ratio,the heat flux angle and the laminate stacking sequence in symmetric composite laminate containing triangular,square and pentagonal cutouts was studied.The Neumann boundary condition was used at the edges of the thermally insulated polygonal cutout.The laminate was made of graphite/epoxy(AS/3501) material with two different stacking sequences of [30/45]sand[30/0/-30]_(s).The analytical solutions were well validated against finite element results.展开更多
The intense deformation zone in the central Indian Ocean, south of Indian continent is one of the most complex regions in terms of its structure and geodynamics. The deformation zone has been studied and debated in 19...The intense deformation zone in the central Indian Ocean, south of Indian continent is one of the most complex regions in terms of its structure and geodynamics. The deformation zone has been studied and debated in 1990s for its genesis. It was argued that deformation is mainly confined to sedimentary and oceanic crustal layers, while the large wave length geoidal anomalies, on which the deformation region lies, called for deeper sources. The inter connection between deeper and the shallower sources is found missing. The current study focuses on the complexities of this region by analyzing OBS (ocean bottom seismometer) data. The data acquired by five OBS systems along a 300 km long south-north profile in the CIOB (central Indian Ocean basin) have been modeled and the crustal and sub-crustal structure has been determined using 2-D tomographic inversion. Four subsurface layers are identified representing the sediment column, upper crustal layer, lower crustal layer and a sub-crustal layer (upper mantle layer). A considerable variation in thickness as well as velocity at all interfaces from sedimentary column to upper mantle is observed which indicates that the tectonic forces have affected the entire crust and sub-crustal configuration. The sediments are characterized by higher velocities (2.1 kin/s) due to the increased confining pressure. Modeling results indicated that the velocity in upper crust is in the range of 5.7-6.2 km/s and the velocity of the lower crust varies from 7.0-7.6 km/s. The velocity of the sub-crustal layer is in the range of 7.8-8.4 km/s. This high-velocity layer is interpreted as magmatic under-plating with strong lateral variations. The base of the 7.0 km/s layer at 12-15 km depth is interpreted as the Moho.展开更多
In this paper,the problem of axially symmetric deformation is examined for a composite cylindrical tube under equal axial loads acting on its two ends,where the tube is composed of two different incompressible neo-Hoo...In this paper,the problem of axially symmetric deformation is examined for a composite cylindrical tube under equal axial loads acting on its two ends,where the tube is composed of two different incompressible neo-Hookean materials.Significantly,the implicit analytical solutions describing the deformation of the tube are proposed.Numerical simulations are given to further illustrate the qualitative properties of the solutions and some meaningful conclusions are obtained.In the tension case,with the increasing axial loads or with the decreasing ratio of shear moduli of the outer and the inner materials,it is proved that the tube will shrink more along the radial direction and will extend more along the axial direction.Under either tension or compression,the deformation along the axial direction is obvious near the two ends of the tube,while in the rest,the change is relatively small.Similarly,for a large domain of the middle part,the axial elongation is almost constant;however,the variation is very fast near the two ends.In addition,the absolute value of the axial displacement increases gradually from the central cross-section of the tube and achieves the maximum at the two endpoints.展开更多
Abnormal conditions are hazardous in complex process systems, and the aim of condition recognition is to detect abnormal conditions and thus avoid severe accidents. The relationship of linkage fluctuation between moni...Abnormal conditions are hazardous in complex process systems, and the aim of condition recognition is to detect abnormal conditions and thus avoid severe accidents. The relationship of linkage fluctuation between monitoring variables can characterize the operation state of the system. In this study,we present a straightforward and fast computational method, the multivariable linkage coarse graining(MLCG) algorithm, which converts the linkage fluctuation relationship of multivariate time series into a directed and weighted complex network. The directed and weighted complex network thus constructed inherits several properties of the series in its structure. Thereby, periodic series convert into regular networks, and random series convert into random networks. Moreover, chaotic time series convert into scale-free networks. It demonstrates that the MLCG algorithm permits us to distinguish, identify, and describe in detail various time series. Finally, we apply the MLCG algorithm to practical observations series, the monitoring time series from a compressor unit, and identify its dynamic characteristics. Empirical results demonstrate that the MLCG algorithm is suitable for analyzing the multivariable linkage fluctuation relationship in complex electromechanical system. This method can be used to detect specific or abnormal operation condition, which is relevant to condition identification and information quality control of complex electromechanical system in the process industry.展开更多
In this paper,CPCM(Composite Phase Change Material)was manufactured with metal foam matrix used as filling material.The temperature curves were obtained by experiment.The performance of heat transfer was analyzed.The ...In this paper,CPCM(Composite Phase Change Material)was manufactured with metal foam matrix used as filling material.The temperature curves were obtained by experiment.The performance of heat transfer was analyzed.The experimental results show that metal foam matrix can improve temperature uniformity in phase change thermal storage material and enhance heat conduction ability.The thermal performance of CPCM is significantly improved.The efficiency of temperature control can be obviously improved by adding metal foam in phase change material.CPCM is in solid-liquid two-phase region when temperature is close to phase change point of paraffin.An approximate plateau appears.The plateau can be considered as the temperature control zone of CPCM.Heat can be transferred fiom hot source and be uniformly spread in thermal storage material by using metal foam matrix since thermal storage material has the advantage of strong heat storage capacity and disadvantage of poor heat conduction ability.Natural convection promotes the melting of solid-liquid phase change material.Good thermal conductivity of foam metal accelerates heat conduction of solid-liquid phase change material.The interior temperature difference decreases and the whole temperature becomes more uniform.For the same porosity with a metal foam,melting time of solid-liquid phase change material decreases.Heat conduction is enhanced and natural convection is suppressed when pore size of metal foam is smaller.The thermal storage time decreases and heat absorption rate increases when the pore size of metal foam reduces.The research results can be used to guide fabricating the CPCM.展开更多
基金Project(51301068)supported by the National Natural Science Foundation of ChinaProject(E2014502003)supported by the Natural Science Foundation of Hebei Province,ChinaProject(2018MS120)supported by Fundamental Research Fund for the Central Universities,China
文摘The distribution of stress and strain between adjacent particles in particulate reinforced metal matrix composites wasinvestigated using cohesive zone models. It is found that the strain of the composite is concentrated in the matrix, and there is aregion with higher strain along the loading path, which can promote the formation of a void near the particles pole. The stress andstrain in matrix near the particles gradually decrease with the increase of the distance between particles. And it is calculated that thereis a critical distance within which the stress and strain fields of the neighboring particles can influence with each other. This criticaldistance increases with the increase of particle size. It is also found that the angle between the tensile direction and the center line ofparticles plays an important role in the stress and strain distribution. The model with the angle of 0° has the greatest influence on thedistribution of stress and strain in the matrix, while the model with the angle of 45° has the least influence on the distribution of stressand strain in the matrix.
基金Supported by Important National Science& Technology Specific Projects (2012ZX10004403,2012ZX10004219)
文摘Flaviviral NS2B is a required cofactor for NS3 serine protease activity and plays an important role in promoting functional NS2B-NS3 protease configuration and maintaining critical interactions with protease catalysis substrates. The residues D80DDG in West Nile virus (WNV) NS2B are important for protease activity. To investigate the effects of D80DDG in NS2B on protease activity and viral replication, the negatively charged region D80DD and the conserved residue G83 of NS2B were mutated (D80DD/E80EE, D80DD/K80KK, D80DD/A80AA, G83F, G83S, G83D, G83K, and G83A), and NS3 D75A was designated as the negative control. The effects of the mutations on NS2B-NS3 activity, viral translation, and viral RNA replication were analyzed using kinetic analysis of site-directed enzymes and a transient replicon assay. All substitutions resulted in significantly decreased enzyme activity and blocked RNA replication. The negative charge of D80DD is not important for maintaining NS2B function, but side chain changes in G83 have dramatic effects on protease activity and RNA replication. These results demonstrate that NS2B is important for viral replication and that D80DD and G83 substitutions prevent replication; they will be useful for understanding the relationship between NS2B and NS3.
文摘In this study,the effect of influencing parameters on the stress distribution around a polygonal cutout within a laminated composite under uniform heat flux was analytically examined.The analytical method was developed based on the classical laminated plate theory and two-dimensional thermo-elastic method.A mapping function was employed to extend the solution of a perforated symmetric laminate with a circular cutout to the solution of polygonal cutouts.The effect of significant parameters such as the cutout angular position,bluntness and aspect ratio,the heat flux angle and the laminate stacking sequence in symmetric composite laminate containing triangular,square and pentagonal cutouts was studied.The Neumann boundary condition was used at the edges of the thermally insulated polygonal cutout.The laminate was made of graphite/epoxy(AS/3501) material with two different stacking sequences of [30/45]sand[30/0/-30]_(s).The analytical solutions were well validated against finite element results.
文摘The intense deformation zone in the central Indian Ocean, south of Indian continent is one of the most complex regions in terms of its structure and geodynamics. The deformation zone has been studied and debated in 1990s for its genesis. It was argued that deformation is mainly confined to sedimentary and oceanic crustal layers, while the large wave length geoidal anomalies, on which the deformation region lies, called for deeper sources. The inter connection between deeper and the shallower sources is found missing. The current study focuses on the complexities of this region by analyzing OBS (ocean bottom seismometer) data. The data acquired by five OBS systems along a 300 km long south-north profile in the CIOB (central Indian Ocean basin) have been modeled and the crustal and sub-crustal structure has been determined using 2-D tomographic inversion. Four subsurface layers are identified representing the sediment column, upper crustal layer, lower crustal layer and a sub-crustal layer (upper mantle layer). A considerable variation in thickness as well as velocity at all interfaces from sedimentary column to upper mantle is observed which indicates that the tectonic forces have affected the entire crust and sub-crustal configuration. The sediments are characterized by higher velocities (2.1 kin/s) due to the increased confining pressure. Modeling results indicated that the velocity in upper crust is in the range of 5.7-6.2 km/s and the velocity of the lower crust varies from 7.0-7.6 km/s. The velocity of the sub-crustal layer is in the range of 7.8-8.4 km/s. This high-velocity layer is interpreted as magmatic under-plating with strong lateral variations. The base of the 7.0 km/s layer at 12-15 km depth is interpreted as the Moho.
基金supported by the National Natural Science Foundation of China(Grant Nos.10872045 and 11232003)the Program for New Century Excellent Talents in University(Grant No.NCET-09-0096)+1 种基金the Fundamental Research Funds for the Central Universities(Grant No.DC120101121)the Program for Liaoning Excellent Talents in University(Grant No.LR2012044)
文摘In this paper,the problem of axially symmetric deformation is examined for a composite cylindrical tube under equal axial loads acting on its two ends,where the tube is composed of two different incompressible neo-Hookean materials.Significantly,the implicit analytical solutions describing the deformation of the tube are proposed.Numerical simulations are given to further illustrate the qualitative properties of the solutions and some meaningful conclusions are obtained.In the tension case,with the increasing axial loads or with the decreasing ratio of shear moduli of the outer and the inner materials,it is proved that the tube will shrink more along the radial direction and will extend more along the axial direction.Under either tension or compression,the deformation along the axial direction is obvious near the two ends of the tube,while in the rest,the change is relatively small.Similarly,for a large domain of the middle part,the axial elongation is almost constant;however,the variation is very fast near the two ends.In addition,the absolute value of the axial displacement increases gradually from the central cross-section of the tube and achieves the maximum at the two endpoints.
基金supported by the National Natural Science Foundation of China(Grant No.51375375)
文摘Abnormal conditions are hazardous in complex process systems, and the aim of condition recognition is to detect abnormal conditions and thus avoid severe accidents. The relationship of linkage fluctuation between monitoring variables can characterize the operation state of the system. In this study,we present a straightforward and fast computational method, the multivariable linkage coarse graining(MLCG) algorithm, which converts the linkage fluctuation relationship of multivariate time series into a directed and weighted complex network. The directed and weighted complex network thus constructed inherits several properties of the series in its structure. Thereby, periodic series convert into regular networks, and random series convert into random networks. Moreover, chaotic time series convert into scale-free networks. It demonstrates that the MLCG algorithm permits us to distinguish, identify, and describe in detail various time series. Finally, we apply the MLCG algorithm to practical observations series, the monitoring time series from a compressor unit, and identify its dynamic characteristics. Empirical results demonstrate that the MLCG algorithm is suitable for analyzing the multivariable linkage fluctuation relationship in complex electromechanical system. This method can be used to detect specific or abnormal operation condition, which is relevant to condition identification and information quality control of complex electromechanical system in the process industry.
基金Support provided by National Basic Research Program of China(Grant No.2012CB933200)National Natural Science Foundation of China(Grant No:51161140332,Grant No.51476172)
文摘In this paper,CPCM(Composite Phase Change Material)was manufactured with metal foam matrix used as filling material.The temperature curves were obtained by experiment.The performance of heat transfer was analyzed.The experimental results show that metal foam matrix can improve temperature uniformity in phase change thermal storage material and enhance heat conduction ability.The thermal performance of CPCM is significantly improved.The efficiency of temperature control can be obviously improved by adding metal foam in phase change material.CPCM is in solid-liquid two-phase region when temperature is close to phase change point of paraffin.An approximate plateau appears.The plateau can be considered as the temperature control zone of CPCM.Heat can be transferred fiom hot source and be uniformly spread in thermal storage material by using metal foam matrix since thermal storage material has the advantage of strong heat storage capacity and disadvantage of poor heat conduction ability.Natural convection promotes the melting of solid-liquid phase change material.Good thermal conductivity of foam metal accelerates heat conduction of solid-liquid phase change material.The interior temperature difference decreases and the whole temperature becomes more uniform.For the same porosity with a metal foam,melting time of solid-liquid phase change material decreases.Heat conduction is enhanced and natural convection is suppressed when pore size of metal foam is smaller.The thermal storage time decreases and heat absorption rate increases when the pore size of metal foam reduces.The research results can be used to guide fabricating the CPCM.