延迟整流钾通道 (IK)主要参与心肌动作电位的复极过程。其至少包含两种成分 :快速激活成分 (Ikr)和缓慢激活成分 (Iks)。目前 IK 通道的分子基础已趋阐明 ,HERG,Kv L QT1 或 min K基因突变均可抑制 IK 流 (Ikr或 Iks) ,导致心肌复极延...延迟整流钾通道 (IK)主要参与心肌动作电位的复极过程。其至少包含两种成分 :快速激活成分 (Ikr)和缓慢激活成分 (Iks)。目前 IK 通道的分子基础已趋阐明 ,HERG,Kv L QT1 或 min K基因突变均可抑制 IK 流 (Ikr或 Iks) ,导致心肌复极延长 ,最终可产生 QT延长综合征 (L QTS)展开更多
In situ capping is an attractive and cost-effective method for remediation of contaminated sediments,but few studies on enhancing contaminant degradation in sediment caps have been reported,especially for chlorinated ...In situ capping is an attractive and cost-effective method for remediation of contaminated sediments,but few studies on enhancing contaminant degradation in sediment caps have been reported,especially for chlorinated benzenes.Electrically enhanced bioactive barrier is a new process for in situ remediation for reducible compounds in soil or sediments.The primary objective of this study is to determine if electrodes in sediment could create a redox gradient and provide electron acceptor/donor to stimulate degradation of chlorinated contaminant.The results demonstrate that graphite electrodes lead to sustainable evolution of hydrogen,displaying zero-order kinetics in the initial stages with different voltages.The constant rates of hydrogen evolution at 3,4,and 5 V are1.05,2.54,and 4.3 nmol·L 1·d 1,respectively.Even higher voltage can produce more hydrogen,but it could not keep long time because the over potentials on electrode surfaces prevent its function.The study shows that 4 V is more appropriate for hydrogen evolution.The measured and evaluated concentration of 1,2,3,5-tetrachlorobenzene in pore water of sediment and concentration of sulfate show that dechlorination is inhibited at higher concentration of sulfate.展开更多
基金Supported by the National Natural Science Foundation of China（51108317） the Municipal Natural Science Foundation of Tianjin（12JCQNJC05400）
文摘In situ capping is an attractive and cost-effective method for remediation of contaminated sediments,but few studies on enhancing contaminant degradation in sediment caps have been reported,especially for chlorinated benzenes.Electrically enhanced bioactive barrier is a new process for in situ remediation for reducible compounds in soil or sediments.The primary objective of this study is to determine if electrodes in sediment could create a redox gradient and provide electron acceptor/donor to stimulate degradation of chlorinated contaminant.The results demonstrate that graphite electrodes lead to sustainable evolution of hydrogen,displaying zero-order kinetics in the initial stages with different voltages.The constant rates of hydrogen evolution at 3,4,and 5 V are1.05,2.54,and 4.3 nmol·L 1·d 1,respectively.Even higher voltage can produce more hydrogen,but it could not keep long time because the over potentials on electrode surfaces prevent its function.The study shows that 4 V is more appropriate for hydrogen evolution.The measured and evaluated concentration of 1,2,3,5-tetrachlorobenzene in pore water of sediment and concentration of sulfate show that dechlorination is inhibited at higher concentration of sulfate.
