A low-voltage, low-power, and high-gain rail-to-rail operational amplifier (OpAmp) is presented. The replica-amplifier gain enhancement technique is applied to improve the DC gain of the amplifier, which does not de...A low-voltage, low-power, and high-gain rail-to-rail operational amplifier (OpAmp) is presented. The replica-amplifier gain enhancement technique is applied to improve the DC gain of the amplifier, which does not degrade the output swing and is very suitable for low-voltage applications. In a 0. 18/μm standard CMOS process,a 1V OpAmp with rail-to-rail output is designed. For a load capacitance of 5 pF,simulation by HSPICE shows that this OpAmp achieves an effective open-loop DC gain of 65. 9dB,gain bandwidth of 70.28 MHz,and phase margin of 50 with a quiescent power dissipation of 156.7μW.展开更多
Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular an...Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular aneurysm repair has rapidly expanded since its first introduction in 1990s.As a less invasive technique,endovascular aneurysm repair has been confirmed to be an effective alternative to open surgical repair,especially in patients with co-morbid conditions.Computed tomography (CT) angiography is currently the preferred imaging modality for both preoperative planning and post-operative follow-up.2D CT images are complemented by a number of 3D reconstructions which enhance the diagnostic applications of CT angiography in both planning and follow-up of endovascular repair.CT has the disadvantage of high cummulative radiation dose,of particular concern in younger patients,since patients require regular imaging follow-ups after endovascular repair,thus,exposing patients to repeated radiation exposure for life.There is a trend to change from CT to ultrasound surveillance of endovascular aneurysm repair.Medical image visualizations demonstrate excellent morphological assessment of aneurysm and stent-grafts,but fail to provide hemodynamic changes caused by the complex stent-graft device that is implanted into the aorta.This article reviews the treatment options of abdominal aortic aneurysm,various image visualization tools,and follow-up procedures with use of different modalities including both imaging and computational fluid dynamics methods.Future directions to improve treatment outcomes in the follow-up of endovascular aneurysm repair are outlined.展开更多
Because of the incomparable merits (nontoxicity, non-remainder, fast transfer mass) of supercritical carbon dioxide fluid technique(SC-CO2), it was used to developed a series of novel biodegradable tissue engineer...Because of the incomparable merits (nontoxicity, non-remainder, fast transfer mass) of supercritical carbon dioxide fluid technique(SC-CO2), it was used to developed a series of novel biodegradable tissue engineering scaffold materials in this research. The novel PLA/chitosan composite materials could be molded to different shapes, and the porosity of the materials were over 200 lam and connected. Chondrocyte cultivation, subcutaneous and intramuscular implantation were mainly discussed this paper. The results showed that the cells could well adhere, grow and multiplicate on the surface of the materials, which indicated good biocompatibility of the composite materials. The plantation test revealed that the PLA materials had already dismissed 2 month late in the body, while the composite materials could still keep certain strength and shape, and the most important things is the response of the tissue toward the implanted PLA/chitosan composite materials was mild and had far less inflammation than PLA materials. 8 to 16 weeks later, fiber membrane was stable; degradation of the materials was seen clear and tissue had already spread into it.展开更多
Liquid metal(LM) has shown potential values in different areas. Attempts to implement LM are tending to develop new functions and make it versatile to improve its performance for practical applications.Here, we presen...Liquid metal(LM) has shown potential values in different areas. Attempts to implement LM are tending to develop new functions and make it versatile to improve its performance for practical applications.Here, we present an unprecedented LM-integrated ultra-elastic microfiber with distinctive features for wearable electronics. The microfiber with a polyurethane shell and an LM core was continuously generated by using a sequenced microfluidic spinning and injection method. Due to the precise fluid manipulation of microfluidics, the resultant microfiber could be tailored with tunable morphologies and responsive conductivities. We have demonstrated that the microfiber could act as dynamic force sensor and motion indicator when it was embedded into elastic films. In addition, the values of the LMintegrated ultra-elastic microfiber on energy conversions such as electro-magnetic or electro-thermal conversions have also been realized. These features indicate that LM-integrated microfiber will open up new frontiers in LM-integrated materials and the wearable electronics field.展开更多
文摘A low-voltage, low-power, and high-gain rail-to-rail operational amplifier (OpAmp) is presented. The replica-amplifier gain enhancement technique is applied to improve the DC gain of the amplifier, which does not degrade the output swing and is very suitable for low-voltage applications. In a 0. 18/μm standard CMOS process,a 1V OpAmp with rail-to-rail output is designed. For a load capacitance of 5 pF,simulation by HSPICE shows that this OpAmp achieves an effective open-loop DC gain of 65. 9dB,gain bandwidth of 70.28 MHz,and phase margin of 50 with a quiescent power dissipation of 156.7μW.
文摘Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular aneurysm repair has rapidly expanded since its first introduction in 1990s.As a less invasive technique,endovascular aneurysm repair has been confirmed to be an effective alternative to open surgical repair,especially in patients with co-morbid conditions.Computed tomography (CT) angiography is currently the preferred imaging modality for both preoperative planning and post-operative follow-up.2D CT images are complemented by a number of 3D reconstructions which enhance the diagnostic applications of CT angiography in both planning and follow-up of endovascular repair.CT has the disadvantage of high cummulative radiation dose,of particular concern in younger patients,since patients require regular imaging follow-ups after endovascular repair,thus,exposing patients to repeated radiation exposure for life.There is a trend to change from CT to ultrasound surveillance of endovascular aneurysm repair.Medical image visualizations demonstrate excellent morphological assessment of aneurysm and stent-grafts,but fail to provide hemodynamic changes caused by the complex stent-graft device that is implanted into the aorta.This article reviews the treatment options of abdominal aortic aneurysm,various image visualization tools,and follow-up procedures with use of different modalities including both imaging and computational fluid dynamics methods.Future directions to improve treatment outcomes in the follow-up of endovascular aneurysm repair are outlined.
基金This work was supported by the national key project“973”program of China.(No.G1999054306)“863”program of ministry of education in China(2OOlAA625050)Guangdong Science and technology bureau(No.A302020104).
文摘Because of the incomparable merits (nontoxicity, non-remainder, fast transfer mass) of supercritical carbon dioxide fluid technique(SC-CO2), it was used to developed a series of novel biodegradable tissue engineering scaffold materials in this research. The novel PLA/chitosan composite materials could be molded to different shapes, and the porosity of the materials were over 200 lam and connected. Chondrocyte cultivation, subcutaneous and intramuscular implantation were mainly discussed this paper. The results showed that the cells could well adhere, grow and multiplicate on the surface of the materials, which indicated good biocompatibility of the composite materials. The plantation test revealed that the PLA materials had already dismissed 2 month late in the body, while the composite materials could still keep certain strength and shape, and the most important things is the response of the tissue toward the implanted PLA/chitosan composite materials was mild and had far less inflammation than PLA materials. 8 to 16 weeks later, fiber membrane was stable; degradation of the materials was seen clear and tissue had already spread into it.
基金supported by the National Natural Science Foundation of China (61927805)the Natural Science Foundation of Jiangsu (BE2018707)+1 种基金the Scientific Research Foundation of Nanjing Universitythe Scientific Research Foundation of Drum Tower Hospital。
文摘Liquid metal(LM) has shown potential values in different areas. Attempts to implement LM are tending to develop new functions and make it versatile to improve its performance for practical applications.Here, we present an unprecedented LM-integrated ultra-elastic microfiber with distinctive features for wearable electronics. The microfiber with a polyurethane shell and an LM core was continuously generated by using a sequenced microfluidic spinning and injection method. Due to the precise fluid manipulation of microfluidics, the resultant microfiber could be tailored with tunable morphologies and responsive conductivities. We have demonstrated that the microfiber could act as dynamic force sensor and motion indicator when it was embedded into elastic films. In addition, the values of the LMintegrated ultra-elastic microfiber on energy conversions such as electro-magnetic or electro-thermal conversions have also been realized. These features indicate that LM-integrated microfiber will open up new frontiers in LM-integrated materials and the wearable electronics field.