AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation pro...AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.展开更多
AIM:To investigate the efficacy and safety of propofol sedation for endoscopic retrograde cholangiopancreatography(ERCP).METHODS:Databases including PubMed,Embase,and the Cochrane Central Register of Controlled Trials...AIM:To investigate the efficacy and safety of propofol sedation for endoscopic retrograde cholangiopancreatography(ERCP).METHODS:Databases including PubMed,Embase,and the Cochrane Central Register of Controlled Trials updated as of October 2010 were searched.Main outcome measures were ERCP procedure duration,recovery time,incidence of hypotension and hypoxia.RESULTS:Six trials with a total of 663 patients were included.The pooled mean difference in ERCP procedure duration between the propofol and traditional sedative agents was-8.05(95%CI:-16.74 to 0.63),with no significant difference between the groups.Thepooled mean difference in the recovery time was-18.69(95%CI:-25.44 to-11.93),which showed a significant reduction with use of propofol sedation.Compared with traditional sedative agents,the pooled OR with propofol sedation for ERCP causing hypotension or hypoxia was 1.69(95%CI:0.82-3.50)and 0.90(95%CI:0.55-1.49),respectively,which indicated no significant difference between the groups.CONCLUSION:Propofol sedation during ERCP leads to shorter recovery time without an increase of cardiopulmonary side effects.Propofol sedation can provide adequate sedation during ERCP.展开更多
OBJECTIVE:To objectively evaluate the clinically curative effect of sidong wubu method on closed fracture of upper limbs.METHODS:A single-blind randomized controlled trial was used to divide 654 patients with closed f...OBJECTIVE:To objectively evaluate the clinically curative effect of sidong wubu method on closed fracture of upper limbs.METHODS:A single-blind randomized controlled trial was used to divide 654 patients with closed fracture of upper limbs at early stage into two groups.298 patients in the surgical group were treated with open reduction and internal fixation and 356 patients in the treatment group with sidong wubu method for 6 months as a course of treatment.RESULTS:As for short-term curative effect(after 6 courses of treatment),the total effective rate was 97.7% in the treatment group and 92.9% in the control group,and the excellent and good rate was 83.7% and 76.5% respectively.Fracture-healing time,treatment cost,function-recovering time,scores of symptoms and signs obviously declined in both groups with remarkable difference between the two groups.As to long-term curative effect(after follow-up visit for one year to 5 years and 2 months),there was still noticeable difference(χ 2 = 7.536,P<0.05) in total curative effect and in excellent and good rate between the two groups.CONCLUSION:With low cost,short treatment course,good function and other advantages,sidong wubu method can be first used to treat closed fracture of upper limbs.展开更多
The application of hard/soft composite structure in personnel armor for blast mitigation is relatively practical and effective in realistic protection engineering,such as the shell/liner system of the helmet.However,t...The application of hard/soft composite structure in personnel armor for blast mitigation is relatively practical and effective in realistic protection engineering,such as the shell/liner system of the helmet.However,there is still lacking a reliable experi-mental methodology to effectively evaluate the blast mitigation performance when the structure directly contacts the protected target,which limits the development of protection structures.In this paper,we proposed a new method to evaluate experi-mentally and numerically the blast mitigation performance of hard/soft composite structures.The blast mitigation mechanism is analyzed.The hard/soft structures were composed of ultra-high molecular weight polyethylene(UHMWPE)composite and expanded polyethylene(EPE)foam.In field explosion experiment,a 7.0 kg trinitrotoluene(TNT)spherical charge is used to generate blast waves at a 3.8 m stand-off distance.A pressure test device is designed to support the tested structure and measure the transmitted blast pressure pulses after passing through the structure.Experimental results indicate that the hard/soft structures can mitigate the blast pressure pulse into the triangular pressure pulse,through making the pulse profile flatter,reducing the pressure amplitude,and delaying the pulse arrival time.Specifically,the combination of 7 mm UHMWPE composite and 20 mm EPE foam can reduce the blast pressure amplitude by 40%.Correspondingly,the finite element simulation is also carried out to understand the blast mitigation mechanism.The numerical results indicate that the regulation for blast pressure pulses mainly complete at the hard/soft interface,which is attributed to the reflection of pressure waves at the interface and the deformation of the soft layer compressed by the hard layer possessing kinetic energy.Furthermore,based on these analyses,the corresponding theoretical model is proposed,and it can well explain the experimental and numerical results.This study is meaningful for evaluating and designing high-performance blast mitigation structures.展开更多
基金Supported by Social Development Fund of Jiangsu Province,No. BS2007054
文摘AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.
基金Supported by The grants from the Department of Anesthesiology and Intensive Care of Changhai Hospital,Shanghai,China
文摘AIM:To investigate the efficacy and safety of propofol sedation for endoscopic retrograde cholangiopancreatography(ERCP).METHODS:Databases including PubMed,Embase,and the Cochrane Central Register of Controlled Trials updated as of October 2010 were searched.Main outcome measures were ERCP procedure duration,recovery time,incidence of hypotension and hypoxia.RESULTS:Six trials with a total of 663 patients were included.The pooled mean difference in ERCP procedure duration between the propofol and traditional sedative agents was-8.05(95%CI:-16.74 to 0.63),with no significant difference between the groups.Thepooled mean difference in the recovery time was-18.69(95%CI:-25.44 to-11.93),which showed a significant reduction with use of propofol sedation.Compared with traditional sedative agents,the pooled OR with propofol sedation for ERCP causing hypotension or hypoxia was 1.69(95%CI:0.82-3.50)and 0.90(95%CI:0.55-1.49),respectively,which indicated no significant difference between the groups.CONCLUSION:Propofol sedation during ERCP leads to shorter recovery time without an increase of cardiopulmonary side effects.Propofol sedation can provide adequate sedation during ERCP.
基金Supported by key disciplines of Shaanxi provincial educational departmentspecial fund for national clinical key specialties of Health Ministry
文摘OBJECTIVE:To objectively evaluate the clinically curative effect of sidong wubu method on closed fracture of upper limbs.METHODS:A single-blind randomized controlled trial was used to divide 654 patients with closed fracture of upper limbs at early stage into two groups.298 patients in the surgical group were treated with open reduction and internal fixation and 356 patients in the treatment group with sidong wubu method for 6 months as a course of treatment.RESULTS:As for short-term curative effect(after 6 courses of treatment),the total effective rate was 97.7% in the treatment group and 92.9% in the control group,and the excellent and good rate was 83.7% and 76.5% respectively.Fracture-healing time,treatment cost,function-recovering time,scores of symptoms and signs obviously declined in both groups with remarkable difference between the two groups.As to long-term curative effect(after follow-up visit for one year to 5 years and 2 months),there was still noticeable difference(χ 2 = 7.536,P<0.05) in total curative effect and in excellent and good rate between the two groups.CONCLUSION:With low cost,short treatment course,good function and other advantages,sidong wubu method can be first used to treat closed fracture of upper limbs.
基金the Science Challenge Project(Grant No.TZ2018002)the National Natural Science Foundation of China(Grant Nos.11972205 and 11722218)+1 种基金the National Key Research Development Program of China(Grant No.2017YFB0702003)Opening Project of Applied Mechanics and Structure Safety Key Laboratory of Sichuan Province.
文摘The application of hard/soft composite structure in personnel armor for blast mitigation is relatively practical and effective in realistic protection engineering,such as the shell/liner system of the helmet.However,there is still lacking a reliable experi-mental methodology to effectively evaluate the blast mitigation performance when the structure directly contacts the protected target,which limits the development of protection structures.In this paper,we proposed a new method to evaluate experi-mentally and numerically the blast mitigation performance of hard/soft composite structures.The blast mitigation mechanism is analyzed.The hard/soft structures were composed of ultra-high molecular weight polyethylene(UHMWPE)composite and expanded polyethylene(EPE)foam.In field explosion experiment,a 7.0 kg trinitrotoluene(TNT)spherical charge is used to generate blast waves at a 3.8 m stand-off distance.A pressure test device is designed to support the tested structure and measure the transmitted blast pressure pulses after passing through the structure.Experimental results indicate that the hard/soft structures can mitigate the blast pressure pulse into the triangular pressure pulse,through making the pulse profile flatter,reducing the pressure amplitude,and delaying the pulse arrival time.Specifically,the combination of 7 mm UHMWPE composite and 20 mm EPE foam can reduce the blast pressure amplitude by 40%.Correspondingly,the finite element simulation is also carried out to understand the blast mitigation mechanism.The numerical results indicate that the regulation for blast pressure pulses mainly complete at the hard/soft interface,which is attributed to the reflection of pressure waves at the interface and the deformation of the soft layer compressed by the hard layer possessing kinetic energy.Furthermore,based on these analyses,the corresponding theoretical model is proposed,and it can well explain the experimental and numerical results.This study is meaningful for evaluating and designing high-performance blast mitigation structures.