Objective： To investigate the efficacy of buried purse-string suture in the treatment of mallet finger deformities. Methods： From February 2009 to February 2010, 12 patients with closed non-fracture mallet fingers ...Objective： To investigate the efficacy of buried purse-string suture in the treatment of mallet finger deformities. Methods： From February 2009 to February 2010, 12 patients with closed non-fracture mallet fingers were treated by buried purse-string suture. The rupture tendons were sutured by purse-string suture with an atraumatic needle, and the knots were buried under subcutaneous tissue. External fixator was used at the extension position of the finger every night within three weeks after operation. Results： All patients were followed up for 6-12 months, mean 7 months. According to the Patel＇s evaluation criteria, 2 cases （17%） obtained excellent results, 7 good （58%）, 2 fair （17%） and 1 poor （8%）. The overall rate of the cases with excellent and good outcomes was 75%. Conclusion： Buried purse-string suture is an easy and effective way to treat mallet finger deformities, with no serious postoperative complications or no need for reoperation.展开更多
Purpose： To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy. Methods： With the patients＇ informed consent, par...Purpose： To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy. Methods： With the patients＇ informed consent, parts of tissue samples were obtained from a 51-year-old diabetic patient who was suffering lower extremity ulcers. The samples were processed with hematoxylin and eosin （HE） staining and Masson trichrome staining. The keratin 19, keratin 15 and carcinoembryonic antigen （CEA） were immunohistochemically detected. Results： The results of HE staining showed that the specimen was divided into two regions, newborn area and original epithelial area. There were more inflammatory cells infiltrating in the dermis in the newborn epithelial area, compared with the original epithelial area. Cells in newborn epithelial area were more active and many dinuclear and polynuclear cells were observed in newborn epithelial area. But there were more cuticular layers and obvious rete pegs in original epithelial area. In addition, the cells with keratin 19 and CEA positive were found around hair follicle, while keratin 15 was negative. Masson trichrome staining showed that there was a lot of de novo collagen in newborn epithelial area. Conclusion： Epidermal cells on the fascia side of the flap could be derived from the stem cells. Negative pressure wound therapy would attract not only cells but also other elements such as growth factors, cytokines, some nutrients and extracellular matrix. With the formation of the appropriate microenvironment after debridement, the migrated cells can grow, differentiate and spread, eventually leading to the epithelization on the fascia side of the flap in diabetic foot.展开更多
文摘Objective： To investigate the efficacy of buried purse-string suture in the treatment of mallet finger deformities. Methods： From February 2009 to February 2010, 12 patients with closed non-fracture mallet fingers were treated by buried purse-string suture. The rupture tendons were sutured by purse-string suture with an atraumatic needle, and the knots were buried under subcutaneous tissue. External fixator was used at the extension position of the finger every night within three weeks after operation. Results： All patients were followed up for 6-12 months, mean 7 months. According to the Patel＇s evaluation criteria, 2 cases （17%） obtained excellent results, 7 good （58%）, 2 fair （17%） and 1 poor （8%）. The overall rate of the cases with excellent and good outcomes was 75%. Conclusion： Buried purse-string suture is an easy and effective way to treat mallet finger deformities, with no serious postoperative complications or no need for reoperation.
基金This work was supported by Research and Innovation Project of Shanghai Municipal Education Commission （No. 14YZ040） and National Natural Science Foundation of China （No. 81671916）.
文摘Purpose： To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy. Methods： With the patients＇ informed consent, parts of tissue samples were obtained from a 51-year-old diabetic patient who was suffering lower extremity ulcers. The samples were processed with hematoxylin and eosin （HE） staining and Masson trichrome staining. The keratin 19, keratin 15 and carcinoembryonic antigen （CEA） were immunohistochemically detected. Results： The results of HE staining showed that the specimen was divided into two regions, newborn area and original epithelial area. There were more inflammatory cells infiltrating in the dermis in the newborn epithelial area, compared with the original epithelial area. Cells in newborn epithelial area were more active and many dinuclear and polynuclear cells were observed in newborn epithelial area. But there were more cuticular layers and obvious rete pegs in original epithelial area. In addition, the cells with keratin 19 and CEA positive were found around hair follicle, while keratin 15 was negative. Masson trichrome staining showed that there was a lot of de novo collagen in newborn epithelial area. Conclusion： Epidermal cells on the fascia side of the flap could be derived from the stem cells. Negative pressure wound therapy would attract not only cells but also other elements such as growth factors, cytokines, some nutrients and extracellular matrix. With the formation of the appropriate microenvironment after debridement, the migrated cells can grow, differentiate and spread, eventually leading to the epithelization on the fascia side of the flap in diabetic foot.
