永久性心房颤动外科双极射频消融术的效果

目的了解外科双极射频消融术治疗永久性心房颤动(AF)同期行风湿性心脏病瓣膜置换术的效果。方法自2006年3月至2010年10月中山大学附属第一医院收治风湿性心瓣膜病合并心房颤动患者124例,按照抛硬币法随机分成射频消融组(n=62)和对照组(n=62),比较两组患者的临床资料、体外循环(CPB)时间、主动脉阻断(ACC)时间、术后机械通气时间、ICU治疗情况、并发症及随访结果。结果两组患者临床资料比较差异无统计学意义(P>0.05)。射频消融组患者术后住院时间较对照组长[(15.8±6.1)d vs.(12.9±3.1)d,P=0.001],CPB和ACC时间两组间比较差异无统计学意义(P>0.05)。两组患者均无需放置永久起搏器,术后左心室射血分数(LVEF)两组比较差异有统计学意义(59.6%±9.2%vs.55.5%±5.4%,P<0.01)。在6个月、12个月、18个月和24个月随访时射频消融组窦性心律维持率分别为88.5%、87.5%、87.1%和82.4%,对照组分别为3.3%、2.2%、0.0%和0.0%,两组比较差异有统计学意义(P<0.05)。结论外科双极射频消融术能有效治疗永久性心房颤动。

Comparison of the Outcomes of Monopolar and Bipolar Radiofrequency Ablation in Surgical Treatment of Atrial Fibrillation

Objective To compare the therapeutic effects and safety of monopolar and bipolar radiofrequency(RF) ablation used during cardiac surgery to treat atrial fibrillation.Methods We retrospectively studied a total of 81 patients with chronic atrial fibrillation who underwent open cardiac surgery with concomitant RF ablation between January 2007 and March 2011.Fifty-eight patients received bipolar RF ablation and 23 received monopolar RF ablation,respectively.The sinus rhythm restoration rate,the procedural duration,the frequency of severe perioperative complications,and mortality were compared between the two groups.Results The sinus rhythm restoration rate did not differ significantly between the two groups after follow-up of 15.1 ± 12.6 months(P=0.199).The frequencies of severe perioperative complications and mortality were also similar in the two groups.The total procedural time using bipolar RF ablation was significantly shorter than that using monopolar ablation(19.7±4.6 minutes vs.28.1±8.5 minutes,P< 0.001).Conclusions Both monopolar and bipolar RF ablation are safe and effective in treating chronic atrial fibrillation patients during open cardiac surgery,but bipolar RF ablation is more convenient in practice.