The development of the heart-lung machine made repair of intracardiac lesions possible. One of the key requirements of the heart-lung machine was anticoagulation. Heparin was discovered by a medical student, Jay McLea...The development of the heart-lung machine made repair of intracardiac lesions possible. One of the key requirements of the heart-lung machine was anticoagulation. Heparin was discovered by a medical student, Jay McLean, working in the laboratory of Dr. William Howell at Johns Hopkins. John Gibbon contributed more to the successful development of the heart-lung machine than anyone else. His interest began as a young doctor since 1930s. Gibbon＇s work on the heart-lung machine took place over the next 20 years in laboratories at Massachusetts General Hospital, the University of Pennsylvania, and Thomas Jefferson University In 1937, he reported the first successful demonstration that life could be maintained by an artificial heart and lung, and the native heart and lungs could resume fimction. After World War II, Dr. Gibbon resumed his work and received support from IBM to build a heart-lung machine on a more sophisticated scale. Eventually, the team developed a larger oxygenator that the IBM engineers incorporated into a new machine. On May 6, 1953, Dr. Gibbon performed the first successful operation using an extracorporeal circuit on an 18-year-old girl with a large atrial septal defect. It wasn＇t until 1958, when a system that involved bubbling blood was perfected, that ＂heart-lung＂ machines came of age. Despite so many chill winds and cold rains, ＂heart-lung＂ machine, the budding rose of surgery, was eventually blossom brightly in the radiant rays of sunlight. John Gibbon＇s dream had become a reality. His work serves as an important example to surgeons who are struggling today with the surgical therapies and technologies of tomorrow.展开更多
The present study was conducted to evaluate minimally invasive tube cystostomy technique in goats and calves suffering from obstructive urolithiasis having intact and ruptured urinary bladder. This clinical study was ...The present study was conducted to evaluate minimally invasive tube cystostomy technique in goats and calves suffering from obstructive urolithiasis having intact and ruptured urinary bladder. This clinical study was carried out on 84 clinical cases （61 goats and 23 calves） based on the history, clinical signs and physical examination along with common laboratory techniques at the Chittagong Veterinary and Animal Sciences University during January 2015-December 2016. Physical parameters like heart rate, respiratory rate, rectal temperature and dehydration status of animals were noted and corrected abnormality before surgery. Some cases had slightly higher haemoglobin （Hb）, packed cell volume （PCV） and uric acid and epithelial casts in urine. The study revealed that abnormal calcium-phosphorus ratio was predisposing the animals to urolithiasis. It was found that young ruminants （3-5 months） were most commonly affected in both species. All affected animals were male in this study, in which calves were not castrated but in goats 95.08% animals were castrated. Rupture of bladder was more common in calves as compared to goats. Postoperatively all cases were administered with broad-spectrum antibiotic, anti-inflammatory agent and caliculolytic agents like ammonium chloride. Tube cystostomy with Foley’s catheter was the most satisfactory technique for the management of obstructive urolithiasis in small ruminants. Postoperative complications were recorded only in four animals and remaining 80 animals had a normal recovery from tube cystostomy. Tube cystostomy is a simple, inexpensive and very effective procedure for the treatment of urolithiasis in ruminants.展开更多
文摘The development of the heart-lung machine made repair of intracardiac lesions possible. One of the key requirements of the heart-lung machine was anticoagulation. Heparin was discovered by a medical student, Jay McLean, working in the laboratory of Dr. William Howell at Johns Hopkins. John Gibbon contributed more to the successful development of the heart-lung machine than anyone else. His interest began as a young doctor since 1930s. Gibbon＇s work on the heart-lung machine took place over the next 20 years in laboratories at Massachusetts General Hospital, the University of Pennsylvania, and Thomas Jefferson University In 1937, he reported the first successful demonstration that life could be maintained by an artificial heart and lung, and the native heart and lungs could resume fimction. After World War II, Dr. Gibbon resumed his work and received support from IBM to build a heart-lung machine on a more sophisticated scale. Eventually, the team developed a larger oxygenator that the IBM engineers incorporated into a new machine. On May 6, 1953, Dr. Gibbon performed the first successful operation using an extracorporeal circuit on an 18-year-old girl with a large atrial septal defect. It wasn＇t until 1958, when a system that involved bubbling blood was perfected, that ＂heart-lung＂ machines came of age. Despite so many chill winds and cold rains, ＂heart-lung＂ machine, the budding rose of surgery, was eventually blossom brightly in the radiant rays of sunlight. John Gibbon＇s dream had become a reality. His work serves as an important example to surgeons who are struggling today with the surgical therapies and technologies of tomorrow.
文摘The present study was conducted to evaluate minimally invasive tube cystostomy technique in goats and calves suffering from obstructive urolithiasis having intact and ruptured urinary bladder. This clinical study was carried out on 84 clinical cases （61 goats and 23 calves） based on the history, clinical signs and physical examination along with common laboratory techniques at the Chittagong Veterinary and Animal Sciences University during January 2015-December 2016. Physical parameters like heart rate, respiratory rate, rectal temperature and dehydration status of animals were noted and corrected abnormality before surgery. Some cases had slightly higher haemoglobin （Hb）, packed cell volume （PCV） and uric acid and epithelial casts in urine. The study revealed that abnormal calcium-phosphorus ratio was predisposing the animals to urolithiasis. It was found that young ruminants （3-5 months） were most commonly affected in both species. All affected animals were male in this study, in which calves were not castrated but in goats 95.08% animals were castrated. Rupture of bladder was more common in calves as compared to goats. Postoperatively all cases were administered with broad-spectrum antibiotic, anti-inflammatory agent and caliculolytic agents like ammonium chloride. Tube cystostomy with Foley’s catheter was the most satisfactory technique for the management of obstructive urolithiasis in small ruminants. Postoperative complications were recorded only in four animals and remaining 80 animals had a normal recovery from tube cystostomy. Tube cystostomy is a simple, inexpensive and very effective procedure for the treatment of urolithiasis in ruminants.
