肝右动脉变异及其外科意义

肝右动脉是供应肝右叶的终末动脉,解剖变异常见,且变异种类繁多,包括肝右动脉和肝左动脉分叉低、走行变异、迂曲畸形、胆囊动脉分支异常和起源变异。肝右动脉起源变异可分为异位肝右动脉和副肝右动脉两种情况,异位起源动脉包括肠系膜上动脉、腹腔干、腹主动脉、肝总动脉、胃十二指肠动脉、胃左动脉、脾动脉和右肾动脉。肝右动脉变异是肝胆胰脾外科手术不良事件和术后并发症的重要原因,术前对其有充分的认识和掌握,术中细致分离和妥善保护是手术安全的重要保障。

The expression and clinical significance of KAI1 and CD44v6 protein in human osteosarcoma

Objective:To investigate the expressions of KAI1 and CD44v6 in human osteosarcoma and the relationship between expressions of them and their clinic pathological features and prognosis.Methods:The expressions of KAI1 and CD44v6 in 87 samples with osteosarcoma were detected by S-P immunohistochemistry.Results:Expression of KAI1 had correlation with metastasis of osteosarcoma,and was strongly associated with differentiation of tumor cells.The expression of CD44v6 in osteosarcoma had correlation with metastasis.There was no difference between the expression of KAI1 and CD44v6.Cox model analysis showed that the prognostic factors were KAI1 expression,metastasis and Enneking surgical staging system.Conclusion:The abnormal expression of KAI1 and CD44v6 participate metastasis of osteosarcoma,KAI1 expression,metastasis and Enneking surgical staging system can be used to independently predict the prognosis of osteo-sarcoma patients.