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生存结局的多中介变量的中介分析方法比较 被引量:2
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作者 李清雅 魏永越 +2 位作者 施倩雯 段巍巍 陈峰 《中国卫生统计》 CSCD 北大核心 2018年第3期338-342,共5页
目的本研究以生存结局为切入点,探讨含两个中介变量时的中介生存分析模型(Aalen相加风险模型、Cox比例风险模型、加速失效时间AFT模型),为预后的多中介变量分析方法的选择提供应用建议。方法通过统计模拟试验,设定不同的相关系数、效应... 目的本研究以生存结局为切入点,探讨含两个中介变量时的中介生存分析模型(Aalen相加风险模型、Cox比例风险模型、加速失效时间AFT模型),为预后的多中介变量分析方法的选择提供应用建议。方法通过统计模拟试验,设定不同的相关系数、效应比、删失率等,从第一类错误及检验效能等方面对上述三种方法进行统计学性质评价。结果中介变量与暴露的相关系数越大,越容易发现中介变量的中介效应;删失率与效应比对Aalen模型的影响较大,对其他两种模型的影响较小;随着删失率的降低,Aalen模型的第一类错误反而膨胀,故Aalen模型不适用于多中介变量的分析;样本量越大,三种模型的检验效能差别减小且趋于稳定。不同参数设定下,AFT模型的检验效能最大,其次为Cox模型,最后为Aalen模型。结论 AFT模型优于其他两种方法,推荐用于生存结局的多中介变量的中介分析;进行中介分析时需要足够的样本量。 展开更多
关键词 中介分析 多中介变量 生存结局
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基于G-计算的高血压、抑郁在2型糖尿病与认知功能之间的因果多中介分析 被引量:1
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作者 韩梅 孟维静 +6 位作者 陶子琨 杨希 徐雅琪 穆华夏 卜伟晓 王素珍 石福艳 《山东大学学报(医学版)》 CAS 北大核心 2023年第10期101-108,共8页
目的探究2型糖尿病(T2DM)与认知功能之间的直接因果效应,以及高血压和抑郁在其因果关系中的中介效应。方法选取美国国家健康和营养检查调查(NHANES)数据库2013年至2014年60~80岁研究对象1306例,根据是否患T2DM分为对照组和T2DM组。采用G... 目的探究2型糖尿病(T2DM)与认知功能之间的直接因果效应,以及高血压和抑郁在其因果关系中的中介效应。方法选取美国国家健康和营养检查调查(NHANES)数据库2013年至2014年60~80岁研究对象1306例,根据是否患T2DM分为对照组和T2DM组。采用G-计算因果多中介分析方法,分析二分类中介高血压、连续型中介抑郁两变量在T2DM与认知功能间的中介效应,并根据性别进行亚组分析。结果T2DM与动物词语流畅性测试、数字符号替换测试之间直接效应差异均有统计学意义,b和95%CI分别为-0.75(95%CI:-1.45~-0.04)和-4.10(95%CI:-6.02~-2.18)。高血压、抑郁在T2DM暴露与认知功能关系中起到部分中介作用,b和95%CI分别为-0.11(95%CI:-0.21~0.00)和-0.50(95%CI:-0.94~-0.05)。亚组分析结果显示,不同性别的直接、间接效应不同。结论T2DM引起认知功能下降可能由高血压和抑郁介导,性别可能是调节变量,预防、管理及治疗合并症对降低认知功能障碍发生风险有重要作用。 展开更多
关键词 G-计算 因果多中介分析 2型糖尿病 认知功能 高血压 抑郁症
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乡村振兴视角下普惠金融的减贫效应研究 被引量:1
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作者 解垩 何心怡 《安徽行政学院学报》 2021年第3期75-85,共11页
在我国脱贫攻坚战取得了全面胜利、消除了绝对贫困之后,如何巩固拓展脱贫攻坚成果,并与乡村振兴有效衔接,便受到高度关注。文章基于中国家庭金融调查(CHFS)数据,对普惠金融影响农村家庭贫困脆弱性的三条中介路径进行实证研究。结果表明... 在我国脱贫攻坚战取得了全面胜利、消除了绝对贫困之后,如何巩固拓展脱贫攻坚成果,并与乡村振兴有效衔接,便受到高度关注。文章基于中国家庭金融调查(CHFS)数据,对普惠金融影响农村家庭贫困脆弱性的三条中介路径进行实证研究。结果表明:农村家庭普惠金融平均水平较低且家庭间差距较大;家庭普惠金融能显著降低农村家庭发生贫困脆弱性的可能;创业决策和教育支出单条路径的中介作用在高和低贫困线下的作用有所不同;医疗保障水平在两条贫困线下都显著。建议通过多种方式促进普惠金融发展,并为农户创业、教育投资和提高医疗保险保障水平提供支持,从而促进普惠金融通过中介减缓贫困脆弱性作用的发挥。 展开更多
关键词 普惠金融 贫困脆弱性 农村家庭 多中介 乡村振兴
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中国货币供给的宏观效应:一个马尔科夫机制转换的视角
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作者 殷波 《吉首大学学报(社会科学版)》 北大核心 2012年第5期132-143,共12页
在时变和非线性框架下考察了我国货币供给和货币政策实施货币盯住模式的宏观绩效,计量分析结果表明近年来我国货币供给冲击的宏观效应大大减弱,不确定性上升,货币盯住模式的有效性显著下降,同时利率盯住模式的有效性在显著上升。因此在... 在时变和非线性框架下考察了我国货币供给和货币政策实施货币盯住模式的宏观绩效,计量分析结果表明近年来我国货币供给冲击的宏观效应大大减弱,不确定性上升,货币盯住模式的有效性显著下降,同时利率盯住模式的有效性在显著上升。因此在新的市场经济条件下,通过更灵活、调节成本更小、信息量更充分的利率信号监测并引导宏观经济运行成为提高货币政策效率、改善宏观调控的必然选择。同时货币当局还应选择与最终目标的相关性高而不确定性小的单一中介目标。 展开更多
关键词 MS-SVAR方法 货币供给 货币盯住 多中介目标
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Flame Imaging in Meso-scale Porous Media Burner Using Electrical Capacitance Tomography 被引量:5
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作者 陈琪 刘石 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2012年第2期329-336,共8页
This study was conducted to investigate the characteristics of meso-scale combustion.The technique of electrical capacitance tomography(ECT) was used to locate flame position and monitor the effect corresponding to va... This study was conducted to investigate the characteristics of meso-scale combustion.The technique of electrical capacitance tomography(ECT) was used to locate flame position and monitor the effect corresponding to varied air/fuel ratio in a meso-scale combustor.Combustion phenomena including igniting,quenching and unsteady combustion have been visualized using ECT.The method of metallization protecting ECT sensor from high temperature damage and the novel calibration method adapted to ECT monitoring of unknown permittivity flame have been shown to be successful.At the same time,electrical nature of combustion and dielectric characteristics of hy-drocarbon flame were studied.The relationship between flame permittivity and state parameters of combustion gas was demonstrated preliminarily. 展开更多
关键词 electr:ical capacitance tomography meso-scale burner COMBUSTION flame permittivity
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A Potential Model for Cylindrical Pores
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作者 张现仁 汪文川 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2001年第4期348-353,共6页
An analytical potential for cylindrical pores has been derived by introducing a variational method into the integration for the calculation of the interaction energy between the wall molecules and a test molecule, all... An analytical potential for cylindrical pores has been derived by introducing a variational method into the integration for the calculation of the interaction energy between the wall molecules and a test molecule, all of which are represented by Lennard-Jones potential. The model proposed gives good fit to the results from the cylindrical surface model and the pseudoatom model. To test the potential proposed rigorously, we have carried out grand canonical ensemble Monte Carlo(GCMC) simulation of nitrogen in the MCM-41 pore at 77 K, and compared the simulated adsorption isotherm with the experimental data reported in the literature. The simulated isotherm from our model is in almost qualitative agreement with experiment. Consequently, the model proposed provides an explicit and accurate description of cylindrical pores represented by the Lennard-Jones potential. Moreover, the model can be easily applied to a variety of cylindrical pores, ranging from cylindrical surface to finite thickness walls, in both theoretical studies and computer simulations. 展开更多
关键词 potential model cylindrical pores GCMC MCM-41
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The Effect of Corporate Social Responsibility on Employees' Organizational Commitment in High-tech Enterprises of Jiangsu Province--Based on the Mediating Role of Regulatory Focus
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《International English Education Research》 2015年第4期59-62,共4页
With China's rapid economic development, corporate social responsibility (CSR) plays greater impact on its direct stakeholder employees' organizational commitment (EOC). A questionnaire survey was conducted on 4... With China's rapid economic development, corporate social responsibility (CSR) plays greater impact on its direct stakeholder employees' organizational commitment (EOC). A questionnaire survey was conducted on 426 employees of high-tech enterprises within Jiangsu Province. Multiple regression method was used to test the hypothesis based on the questionnaire reliability and validity analysis. The results show that the four dimensions of CSR including employees responsibility, products responsibility, environment responsibility and charitable responsibility have positive effect on the affective commitment;while the continuance commitment might be more influenced by the environment and charitable responsibility. The regulatory focus plays a moderate effect between CSR and EOC. Promote regulatory focus have positive impact on affective commitment and negative impact on continuance commitment. Defense regulatory focus is just on the opposite. 展开更多
关键词 Corporate Social Responsibility Regulatory Focus Employees' Organizational Commitment High-tech enterprises
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Research on the Mediating Effect of Market Benefit Between Dual Distribution Channel Conflicts and Financial Performance of Garment Enterprises
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作者 Yue Yanzai Qu Hongjian 《International English Education Research》 2014年第12期88-92,共5页
The paper discussed the impact of dual distribution channel conflicts on financial performance of garment enterprises by multiple regression and mediation effect has been analyzed with market benefit as the mediated v... The paper discussed the impact of dual distribution channel conflicts on financial performance of garment enterprises by multiple regression and mediation effect has been analyzed with market benefit as the mediated variable based on the survey data of Shanghai region. The results show that: first, channel contention, channel areal differences and channel perception differences have a negative effect on financial performance and channel communication has a positive effect on financial performance significantly; second, market benefit has a positive effect on financial performance significantly; third, channel contention, channel areal differences and channel perception differences have a negative effect on market benefit and channel communication has a positive effect on market benefit significantly; forth, market benefit has a partial mediation effect on the influence of channel areal differences and channel communication on financial performance. Therefore, channel areal differences and channel communication are two major aspects among the dual distribution channel conflicts which may have influences on financial benefit of garment enterprises, and clothing company should lay emphasis on the settling of these two matters. 展开更多
关键词 Dual Distribution Channel Conflicts Financial Performance Mediating Effect Empirical Analysis
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Association of Interleukin-10 Gene Haplotype with Gastric Cancer in a Chinese Population
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作者 Jing-yuan CUI Hong MA +1 位作者 He WANG Feng-bo SUN 《Clinical oncology and cancer researeh》 CAS CSCD 2010年第4期234-239,共6页
OBJECTIVE Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenic functions.Previous studies have reported that IL-10 levels are signifi cantly elevated in patients with g... OBJECTIVE Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenic functions.Previous studies have reported that IL-10 levels are signifi cantly elevated in patients with gastric cancer (GC). It has also been confirmed that interindividual variations in IL-10 production are genetically attributed to the polymorphisms of IL-10 gene.Therefore, this study was designed to investigate whether the polymorphisms of IL-10 gene were associated with susceptibility to GC in the Chinese population.METHODS The serum levels of IL-10 were measured by radioimmunoassay. The single nucleotide polymorphisms (SNPs) at positions -1082A/G, -819T/C and -592A/C in the IL-10 gene promoter were analyzed using polymerase chain reactionrestriction fragment length polymorphism (PCR-RFLP).RESULTS 220 patients with gastric cancer and 180 healthy controls were included in this study. The serum levels of IL-10 were signifi cantly higher in GC patients than healthy controls (Z = -19.13, P 〈 0.001). Single SNP analysis showed that the -1082G allele, -1082AG and -819CC genotypes significantly increased in patients with GC (P = 0.029, 0.021, 0.039 respectively). In a logistic regression analysis adjusted for age and sex, the -1082AG genotype was associated with an odds ratio of 1.974 (95% CI,1.14-3.391; P = 0.014), and the -819CC genotype with an odds ratio of 2.496 (95% CI, 1.222-5.102; P = 0.012) for GC. Furthermore,haplotype analysis revealed that at least five haplotypes (ATA,ACC, GCC, ACA and ATC) were existent in this population.Also that the GCC haplotype was associated with a signifi cantly increased risk of GC as compared with the ATA haplotype (OR =1.90; 95% CI, 1.11-3.27; P = 0.02).CONCLUSION The results indicate that the gene haplotype of IL-10 may contribute to the susceptibility to GC in the Chinese population. 展开更多
关键词 INTERLEUKIN-10 POLYMORPHISM single nucleotide haplotypes stomach neoplasms
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分析师利空关注与公司投资效率:“萝卜”加“大棒”
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作者 陈少凌 周开国 +1 位作者 杨海生 钟嘉颖 《金融研究》 CSSCI 北大核心 2024年第1期150-168,共19页
本文以2009—2020年我国A股上市公司的485366份分析师报告为研究样本,尽可能剥离乐观偏差干扰,考察分析师关注对公司投资效率的真实影响。研究表明:第一,分析师的利空关注会同时抑制过度投资和缓解投资不足,对公司投资效率具有显著的提... 本文以2009—2020年我国A股上市公司的485366份分析师报告为研究样本,尽可能剥离乐观偏差干扰,考察分析师关注对公司投资效率的真实影响。研究表明:第一,分析师的利空关注会同时抑制过度投资和缓解投资不足,对公司投资效率具有显著的提升作用。第二,基于双重纠偏LASSO回归,修正影响机制中可能存在的估计偏误,发现分析师利空关注对投资效率的积极影响,源自施加卖空压力的“大棒效应”以及提供信息增强的“萝卜效应”,且上述两种效应均会通过机构投资者和资本市场这两个渠道共同发力。第三,多中介因果路径分析显示,分析师利空关注的“萝卜效应”强于“大棒效应”,机构投资者渠道的效力强于资本市场渠道的效力。本文为探讨分析师在资本市场中的角色提供了新视角,补充了中国情境下分析师关注影响公司投资效率的经验证据。 展开更多
关键词 分析师利空关注 公司投资效率 信息中介 双重纠偏LASSO 多中介因果路径分析
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不同差错氛围激发团队突破性创造力的机理研究:社会信息处理视角 被引量:11
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作者 耿紫珍 周怡欣 +1 位作者 单春霞 丁琳 《管理评论》 CSSCI 北大核心 2022年第9期221-231,284,共12页
为了揭示不同差错氛围影响团队突破性创造力的内部机理,首先基于社会信息处理理论分析团队突破性创造力形成要素和路径,提出差错管理氛围和差错反感氛围通过影响团队心理、认知和社会互动三方面关键要素(简称三要素)作用于团队突破性创... 为了揭示不同差错氛围影响团队突破性创造力的内部机理,首先基于社会信息处理理论分析团队突破性创造力形成要素和路径,提出差错管理氛围和差错反感氛围通过影响团队心理、认知和社会互动三方面关键要素(简称三要素)作用于团队突破性创造力的理论框架,然后考察差错管理氛围和差错反感氛围对团队突破性创造力的直接效应,以及通过三要素,即团队心理安全感、团队认知柔性和团队建设性辩论作用于团队突破性创造力的平行中介效应,构建不同差错氛围影响团队突破性创造力的“心理-认知-社会”机理模型。采用层次回归、Bootstrap检验和瞬时中介检验等分析方法针对119个创新团队的配对问卷调研数据进行实证检验,研究结果表明:(1)团队心理安全感、团队认知柔性和团队建设性辩论均正向影响团队突破性创造力;(2)差错管理氛围正向影响而差错反感氛围负向影响团队突破性创造力;(3)差错管理氛围正向影响团队心理安全感、团队认知柔性和团队建设性辩论,而差错反感氛围倒U型影响团队建设性辩论和负向影响团队心理安全感;(4)团队心理安全感、团队认知柔性和团队建设性辩论中介了差错管理氛围对团队突破性创造力的影响,团队建设性辩论和团队心理安全感中介了差错反感氛围对团队突破性创造力的影响。研究通过聚焦于团队突破性想法产生源头阐明了不同差错氛围在突破性创新理论和实践发展中的重要作用。 展开更多
关键词 突破性创造力 差错氛围 社会信息处理 多中介模型 瞬时中介检验
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Intermediate Energy Pion-^(20)Ne Elastic Scattering in the α+^(16)O Model of (20)~Ne
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作者 杨永栩 Ong Piet-Tjing 李清润 《Communications in Theoretical Physics》 SCIE CAS CSCD 2013年第11期588-592,共5页
We present an analysis of π-^20Ne elastic scattering at intermediate energy basing on the α+^16O model of the ^20Ne nucleus and in the framework of Glauber multiple scattering theory. Satisfactory agreement with th... We present an analysis of π-^20Ne elastic scattering at intermediate energy basing on the α+^16O model of the ^20Ne nucleus and in the framework of Glauber multiple scattering theory. Satisfactory agreement with the general features of the experimental data of pion elastic scattering on the neighboring 4N-type nuclei is obtained without any free parameters. Compared with the experimental angular distributions of pion elastic scattering on ^12 C, ^16O, ^24Mg, and ^28Si nuclei, the diffractive patterns and the positions of the dips and peaks in the angular distributions of ^π-^20Ne elastic scattering are reasonably predicted by the calculations. 展开更多
关键词 pion-nucleus elastic scattering nuclear cluster model
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