Whether extrapulmonary lesions are avid for18F-fluorodeoxyglucose(18F-FDG) could help to differentiate the benign or malignant lung lesions.In this trial,the 199 consecutive patients with newly diagnosed lung lesions(...Whether extrapulmonary lesions are avid for18F-fluorodeoxyglucose(18F-FDG) could help to differentiate the benign or malignant lung lesions.In this trial,the 199 consecutive patients with newly diagnosed lung lesions(169 malignant and 36 benign lesions) were imaged by whole body18F-FDG PET/CT.Histopathology and clinic results served as the reference standard.The malignancy likelihood were conducted by CTscores;the maximum standardized uptake value(SUVmax) of lung lesions,and PET on FDG negative or positive,as well as metastasis index(MI),by PET combined with CT findings.The data were analyzed by stepwise logistic regression and receiver-operatingcharacteristic.The malignancy predictive probability(P) was obtained by P =ex/(1+ex),where x= –1.16+0.87(CTscore) +0.15(SUVmax)+0.27(MI).The area under curve(AUC) for the fitted logistic model was 0.82±0.04,this was superior and significantly different from SUVmax(AUC,0.73±0.05) and CTscores(AUC,0.71±0.05).The fitted logistic model could improve the diagnostic performance.The MI could help for differential diagnosis.展开更多
经济学家希克斯在其著名论文（1935）中提出了为什么经济单位持有无收益的货币而不是有收益的资本品问题，并认为这个问题在货币纯理论中完全是一个中心问题。经济学家对此问题付出了很大努力，曾先后提出了叠代模型（overlapping gener...经济学家希克斯在其著名论文（1935）中提出了为什么经济单位持有无收益的货币而不是有收益的资本品问题，并认为这个问题在货币纯理论中完全是一个中心问题。经济学家对此问题付出了很大努力，曾先后提出了叠代模型（overlapping generation model）、货币效用模型（money in the utility function model）、预付现金模型（cash in advance constrain model）、随机配对模型（random matching model）等多种模型来试图解决这个货币理论的微观基础问题。一个相关的问题是，目前政府债券和中央银行纸币是由同一个单位（政府）的不同部门发行，为什么有收益的政府债券没能作为交易媒介而替代货币流通呢？这个问题引起了经济学家的关注，视为“货币与债券共存之谜”。展开更多
基金Supported by National Natural Science Foundation of China[Grant No.30800274]
文摘Whether extrapulmonary lesions are avid for18F-fluorodeoxyglucose(18F-FDG) could help to differentiate the benign or malignant lung lesions.In this trial,the 199 consecutive patients with newly diagnosed lung lesions(169 malignant and 36 benign lesions) were imaged by whole body18F-FDG PET/CT.Histopathology and clinic results served as the reference standard.The malignancy likelihood were conducted by CTscores;the maximum standardized uptake value(SUVmax) of lung lesions,and PET on FDG negative or positive,as well as metastasis index(MI),by PET combined with CT findings.The data were analyzed by stepwise logistic regression and receiver-operatingcharacteristic.The malignancy predictive probability(P) was obtained by P =ex/(1+ex),where x= –1.16+0.87(CTscore) +0.15(SUVmax)+0.27(MI).The area under curve(AUC) for the fitted logistic model was 0.82±0.04,this was superior and significantly different from SUVmax(AUC,0.73±0.05) and CTscores(AUC,0.71±0.05).The fitted logistic model could improve the diagnostic performance.The MI could help for differential diagnosis.
文摘经济学家希克斯在其著名论文（1935）中提出了为什么经济单位持有无收益的货币而不是有收益的资本品问题，并认为这个问题在货币纯理论中完全是一个中心问题。经济学家对此问题付出了很大努力，曾先后提出了叠代模型（overlapping generation model）、货币效用模型（money in the utility function model）、预付现金模型（cash in advance constrain model）、随机配对模型（random matching model）等多种模型来试图解决这个货币理论的微观基础问题。一个相关的问题是，目前政府债券和中央银行纸币是由同一个单位（政府）的不同部门发行，为什么有收益的政府债券没能作为交易媒介而替代货币流通呢？这个问题引起了经济学家的关注，视为“货币与债券共存之谜”。
