Conventional rice breeding has long focused on exploiting the DNA sequence diversity.However,epigenetic diversity,reflected particularly in DNA methylation,can also contribute to phenotypic variation and should not be...Conventional rice breeding has long focused on exploiting the DNA sequence diversity.However,epigenetic diversity,reflected particularly in DNA methylation,can also contribute to phenotypic variation and should not be overlooked in rice breeding.In this study,20 parental lines of indica rice,which are widely used in hybrid rice breeding in China,were analyzed to investigate variations of DNA methylation and its inheritance.The results revealed a wide diversity in DNA methylation among these breeding lines.A positive correlation was seen between DNA methylation and genetic diversity.Furthermore,some of the methylated DNA was inherited in the subsequent generation,regardless of whether they were produced by selfing or hybrid-crossing.This study provides insight into the methylation patterns in rice,and suggests the importance of epigenetic diversity in rice breeding.展开更多
Nasopharyngeal carcinoma （NPC） was mostly common in Guangdong Province and Guangxi Chuang Autonomous Region. This cancer jeopardized people＇s health in the above areas. In order to understand the mechanisms for NPC...Nasopharyngeal carcinoma （NPC） was mostly common in Guangdong Province and Guangxi Chuang Autonomous Region. This cancer jeopardized people＇s health in the above areas. In order to understand the mechanisms for NPC, and further promote NPC＇s early diagnosis and therapy, the molecular genetic analysis research of NPC in China and in its outbreak areas becomes an emergent topic. Since NPC is a rare disease in developed countries of Europe and America, the research in this field has not been well-recognized in these countries. Furthermore,展开更多
基金supported by the National Natural Science Foundation of China(31071379)the Post-Doctoral Foundation of China(20090450616)a grant from"Yellow Crane"Special Talent Program of Wuhan
文摘Conventional rice breeding has long focused on exploiting the DNA sequence diversity.However,epigenetic diversity,reflected particularly in DNA methylation,can also contribute to phenotypic variation and should not be overlooked in rice breeding.In this study,20 parental lines of indica rice,which are widely used in hybrid rice breeding in China,were analyzed to investigate variations of DNA methylation and its inheritance.The results revealed a wide diversity in DNA methylation among these breeding lines.A positive correlation was seen between DNA methylation and genetic diversity.Furthermore,some of the methylated DNA was inherited in the subsequent generation,regardless of whether they were produced by selfing or hybrid-crossing.This study provides insight into the methylation patterns in rice,and suggests the importance of epigenetic diversity in rice breeding.
文摘Nasopharyngeal carcinoma （NPC） was mostly common in Guangdong Province and Guangxi Chuang Autonomous Region. This cancer jeopardized people＇s health in the above areas. In order to understand the mechanisms for NPC, and further promote NPC＇s early diagnosis and therapy, the molecular genetic analysis research of NPC in China and in its outbreak areas becomes an emergent topic. Since NPC is a rare disease in developed countries of Europe and America, the research in this field has not been well-recognized in these countries. Furthermore,
