In this paper we introduce some new subclesses of meromorphic multivalent functions. Inclusion relations between these classes, the class preserving integral operators and coefficient estimates are obtained.
AIM To study the uptake of bacterial lipopolysaccharides (LPS) and expression of tumor necrosis factor α mRNA (TNF α mRNA) with cultured rat intrahepatic bile duct epithelial cells.
Water-soluble algal polysaccharides (APS) (alginic acid, fucoidan and laminaran) possess many pharmacological activities. The results of this study showed that the APS- Ce4+ complexes have some enzyme-like activities....Water-soluble algal polysaccharides (APS) (alginic acid, fucoidan and laminaran) possess many pharmacological activities. The results of this study showed that the APS- Ce4+ complexes have some enzyme-like activities. Fucoidan and its complex with Ce4+ have activities similar to those of SOD. The activities of laminaran, alginic acid and their complexes are not measurable. The APS do not show measurable activities in the digestion of plasmid DNA. In contrast, the APS- Ce4+ complexes show these measurable activities under the comparable condition when APS bind Ce4+ and form homogenous solu-tions. The laminaran- Ce4+ complex shows the most obvious activity in the digestion of plasmid DNA, pNPP and chloropy-rifos under neutral conditions.展开更多
The multiphoton ionization of acetone-water clusters were detected at 355 nm laser wavelength by using the time of flight mass spectrometer(TOF-MS). The experiments show that all products are proto- nated. Three mai...The multiphoton ionization of acetone-water clusters were detected at 355 nm laser wavelength by using the time of flight mass spectrometer(TOF-MS). The experiments show that all products are proto- nated. Three main products such as (CH3COCH3),-(H2O)n_2 H^+ , (CH3COCH3),-(H2O)n-1 H^+ and (CH3COCH3),-(H2O),H^+ are concluded from the results. In order to study the equilibrium structures of the (CH3 COCH3 ),-(H2O)n-2 H^+ , the ab-initio calculation is used on them. The experiment is even done when the volume rate of acetone to water is 1:2.展开更多
With the development of economic activities, marine oil pollution is becoming an increasing serious problem. Instead of dissolved in seawater, petroleum hydrocarbons are more easily enriched in sediments, which poses ...With the development of economic activities, marine oil pollution is becoming an increasing serious problem. Instead of dissolved in seawater, petroleum hydrocarbons are more easily enriched in sediments, which poses a serious threat to benthos. In this paper, the research progresses on toxicity of marine petroleum hydrocarbon for polychaetes were reviewed in recent years, including the toxic mechanism of petroleum hydrocarbons, the feeding habits, the effects of petroleum hydrocarbons on the antioxidant defense system, the nervous system damages, the molecular damages of polychaetes under the stress of petroleum hydrocarbon, the accumulation and metabolism of petroleum hydrocarbons in polychaetes. The future research direction were also prospected.展开更多
The changes in arachidonic acid (AA) and fatty acids profiles along the growth curve of Parietochloris incisa, a coccoid snow green alga, were studied in a 2.8 cm light-path flat photobioreactor, exposed to strong pho...The changes in arachidonic acid (AA) and fatty acids profiles along the growth curve of Parietochloris incisa, a coccoid snow green alga, were studied in a 2.8 cm light-path flat photobioreactor, exposed to strong photon flux density [PFD, 2400 μEmol/(m 2·s)]. Sixteen fatty acids were identified by gas chromatography showing that AA was the dominant fatty acid (33%-41%) followed by linoleic acid (17%-21%). AA content was closely investigated with respect to total fatty acids (TFA), ash free dry weight (AFDW) of cell mass as well as total culture content. These parameters were influenced significantly in a similar manner by culture growth phase, i.e., slightly decreasing in the lag period, gradually increasing in the logarithmic phase, becoming maximal at the early stationary phase, starting to decrease at the late stationary phase, sharply dropping at the decline phase. The increase in AA per culture volume during the logarithmic phase was not only associated with the increase in AFDW but also connected with a corresponding increase in AA/TFA, TFA/AFDW as well as AA/AFDW. The sharp decrease in AA content of the culture during the decline phase was mainly due to the decrease in AA/TFA, TFA/AFDW and AA/AFDW, although AFDW declined only a small extent. Maximal AA concentration, obtained at the early stationary phase, was 900 mg/L culture volume, and the average daily net increase of AA during 9 days logarithmic growth was 1.7 g/(m 2·day). Therefore, harvesting prior to the decline phase in a batch culture, or at steady state in continuous culture mode seems best for high AA production. The latter possibility was also further confirmed by continuous culture with 5 gradients of harvesting rate.展开更多
Genetic comparison between Rhynchophorus ferrugineus (Coleoptera: Curculionidae: Rhynchophorinae) and other four Rhynchophorus spp. such as R. bilineatus, R. phoenicis, R. cruentatus and R. palmarum was investigat...Genetic comparison between Rhynchophorus ferrugineus (Coleoptera: Curculionidae: Rhynchophorinae) and other four Rhynchophorus spp. such as R. bilineatus, R. phoenicis, R. cruentatus and R. palmarum was investigated using partial sequences of Cytochrome c oxidase subunit I (COl) mitochondrial gene. The number ofpolymorphic sites ranged from 79 to 102 while the genetic distances ranged from 0.058 to 0.095. The number of polymorphic sites, genetic distances and phylogenetic relationships among R. ferrugineus and the other four tested species revealed that R.ferrugineus was more closely related to R. bilineatus while it was distantly related to R. palmarum. It is possible to rank the five tested species as follows: R.ferrugineus, R. bilineatus, R. phoenicis, R. cruentatus and R. palmarum. The result of this study is the first step of the revision of the uncertain taxonomic status and phylogenetic relationships among the Rhynchophorus genus. Further analysis should be performed using other Rhynchophorus species as well as other molecular markers.展开更多
The report examines the evolution of computers from digital analogs through non-yon Neumann machines to quantum computers, which are also digital analogs. In the 60 years of digital analogs successfully developed at t...The report examines the evolution of computers from digital analogs through non-yon Neumann machines to quantum computers, which are also digital analogs. In the 60 years of digital analogs successfully developed at the Institute of Electromechanics of the USSR in Leningrad. An important stage in the development of non-classical multiprocessor machine performance and reliability has been the development of recursive machines, which was carried out at the Institute of Cybernetics led V.M.Glushkov and the Leningrad Institute of Aviation Instrumentation. The general approach to the synthesis is carried out through linguo- combinatorial modeling with structured uncertainty.展开更多
An experiment was conducted and through distant hybridization a new promising forms of citruses were obtained. Namely, after hybridization of lemon Georgian and broad-leaved mandarin unshiu (mother components) with ...An experiment was conducted and through distant hybridization a new promising forms of citruses were obtained. Namely, after hybridization of lemon Georgian and broad-leaved mandarin unshiu (mother components) with early-ripening trifoliata and a hybrid of citrus ichangensis--"Caucasus" (father components) a wide range of nucellar seedlings were obtained. It should be noted that nucellar seedlings of hybrid nature are practically closer to distant hybrids of sexual origin that are sharply inclined to the side of the mother component and produce good quality fruit. Unfortunately, such hybrids are either very rare or cannot be obtained at all. While, in the case of the study, through using new combinations in hybridization, the possibility of getting nucellar seedlings of the hybrid nature is much bigger. Distant hybridization turned out to be particularly interesting because of the polyembryony of citrus plants. Due to this, it gives opportunity to get new promising forms not only from the egg cell but from nucellar cells as well.展开更多
Qianjinba is primarily cultivated in the southern regions of China and finds extensive use in traditional Chinese medicine(TCM)for conditions such as rheumatism,arthralgia,and gynecological ailments.It has been offici...Qianjinba is primarily cultivated in the southern regions of China and finds extensive use in traditional Chinese medicine(TCM)for conditions such as rheumatism,arthralgia,and gynecological ailments.It has been officially recognized as a protected variety of TCM by the state.The aim of this study was to investigate the therapeutic potential of Qianjinba polysaccharide(QJBDT)in treating rheumatoid arthritis(RA)in mice,along with a preliminary exploration of its mechanisms for inhibiting RA in these animals.Kunming mice(KM)were randomly divided into several groups,including a normal group,a model group(LPS group),low-dose,medium-dose,and high-dose QJBDT groups,as well as a positive control group(TGP group),each consisting of 10 mice.To induce inflammation and create an RA model,type II collagen was injected into the right hind foot joint.Following a 7-day modeling period,various concentrations of QJBDT and the positive control drug total glycoside of peony were administered via gavage once a day for 21 consecutive days.Throughout the study,we monitored and recorded the mice's weight,measured foot swelling,and assessed the arthritis index on a weekly basis.We also conducted pathological examinations of joint tissues and analyzed the signal pathway of p38 mitogen-activated protein kinase(MAPK)as well as the protein expression of nuclear factor NF-κB in the mice’s right foot joint tissues.Additionally,we employed ELISA to detect the levels of interleukin-β(IL-β),IL-17,and tumor necrosis factor-α(TNF-α)in the mice’s serum.The results of this study revealed that QJBDT effectively reduced the degree of foot swelling and the arthritis index in collagen-induced arthritis mice while improving their weight loss(P<0.05).Furthermore,it alleviated the pathological damage observed in the mice’s joints.Notably,the expression of transcription factors p38 and NF-κB proteins was down-regulated(P<0.05),and the levels of inflammatory cytokines IL-β,IL-17,and TNF-αin the mice’s serum were decreased(P<0.05).In conclusion,this study demonstrated that polysaccharides could inhibit the expression of transcription factors p38 and NF-κB,reduce the production of inflammatory factors,and alleviate the progression of RA to a certain extent.展开更多
Taking Terminalia chebula Retz. as the control product, the polyphenolic contents of the processed products in Tibetian, Rubia cordifolia L. processed Terminalia chebula Retz. and Euphorbia fischeriana Steud processed...Taking Terminalia chebula Retz. as the control product, the polyphenolic contents of the processed products in Tibetian, Rubia cordifolia L. processed Terminalia chebula Retz. and Euphorbia fischeriana Steud processed Terminalia chebula Retz. were analyzed by HPLC. Polyphenolic contents increased from 4.54% to 5.69% and 7.46%, respectively, which may lead to the change in their pharmacological effects.展开更多
Let A = F [x, y] be the polynomial algebra on two variables x, y over an algebraically closed field F of characteristic zero. Under the Poisson bracket, A is equipped with a natural Lie algebra structure. It is proven...Let A = F [x, y] be the polynomial algebra on two variables x, y over an algebraically closed field F of characteristic zero. Under the Poisson bracket, A is equipped with a natural Lie algebra structure. It is proven that the maximal good subspace of A* induced from the multiplication of the associative commutative algebra A coincides with the maximal good subspace of A* induced from the Poisson bracket of the Poisson Lie algebra A. Based on this, structures of dual Lie bialgebras of the Poisson type are investigated. As by-products,five classes of new infinite-dimensional Lie algebras are obtained.展开更多
Cyclotides constitute a fascinating family of circular proteins containing ca.30 amino acid residues.They have a unique cyclic cysteine knot topology and exhibit remarkable thermal,chemical and enzymatic stabilities.T...Cyclotides constitute a fascinating family of circular proteins containing ca.30 amino acid residues.They have a unique cyclic cysteine knot topology and exhibit remarkable thermal,chemical and enzymatic stabilities.These characteristics enable them to have a range of biological activities and promising pharmaceutical and agricultural applications.Here,we present a practical strategy for the chemical synthesis of cyclotides through the intramolecular ligation of fully unprotected peptide O-esters.This strategy involves the mild Fmoc solid-phase peptide synthesis of the peptide O-ester backbone,the head-to-tail cyclization of the cyclotide backbone by native chemical ligation,and the oxidative refolding to yield the natural knot protein.The simplicity and high efficiency of the strategy can be employed in the synthesis of artificial cyclotides for pharmaceutical applications.展开更多
In this paper,the authors construct a φ-group for n submodules,which generalizes the classical K-theory and gives more information than the classical ones.This theory is related to the classification theory for indec...In this paper,the authors construct a φ-group for n submodules,which generalizes the classical K-theory and gives more information than the classical ones.This theory is related to the classification theory for indecomposable systems of n subspaces.展开更多
文摘In this paper we introduce some new subclesses of meromorphic multivalent functions. Inclusion relations between these classes, the class preserving integral operators and coefficient estimates are obtained.
文摘AIM To study the uptake of bacterial lipopolysaccharides (LPS) and expression of tumor necrosis factor α mRNA (TNF α mRNA) with cultured rat intrahepatic bile duct epithelial cells.
文摘Water-soluble algal polysaccharides (APS) (alginic acid, fucoidan and laminaran) possess many pharmacological activities. The results of this study showed that the APS- Ce4+ complexes have some enzyme-like activities. Fucoidan and its complex with Ce4+ have activities similar to those of SOD. The activities of laminaran, alginic acid and their complexes are not measurable. The APS do not show measurable activities in the digestion of plasmid DNA. In contrast, the APS- Ce4+ complexes show these measurable activities under the comparable condition when APS bind Ce4+ and form homogenous solu-tions. The laminaran- Ce4+ complex shows the most obvious activity in the digestion of plasmid DNA, pNPP and chloropy-rifos under neutral conditions.
文摘The multiphoton ionization of acetone-water clusters were detected at 355 nm laser wavelength by using the time of flight mass spectrometer(TOF-MS). The experiments show that all products are proto- nated. Three main products such as (CH3COCH3),-(H2O)n_2 H^+ , (CH3COCH3),-(H2O)n-1 H^+ and (CH3COCH3),-(H2O),H^+ are concluded from the results. In order to study the equilibrium structures of the (CH3 COCH3 ),-(H2O)n-2 H^+ , the ab-initio calculation is used on them. The experiment is even done when the volume rate of acetone to water is 1:2.
基金supported by the National Natural Science Foundation of China(No.21677065).
文摘With the development of economic activities, marine oil pollution is becoming an increasing serious problem. Instead of dissolved in seawater, petroleum hydrocarbons are more easily enriched in sediments, which poses a serious threat to benthos. In this paper, the research progresses on toxicity of marine petroleum hydrocarbon for polychaetes were reviewed in recent years, including the toxic mechanism of petroleum hydrocarbons, the feeding habits, the effects of petroleum hydrocarbons on the antioxidant defense system, the nervous system damages, the molecular damages of polychaetes under the stress of petroleum hydrocarbon, the accumulation and metabolism of petroleum hydrocarbons in polychaetes. The future research direction were also prospected.
文摘The changes in arachidonic acid (AA) and fatty acids profiles along the growth curve of Parietochloris incisa, a coccoid snow green alga, were studied in a 2.8 cm light-path flat photobioreactor, exposed to strong photon flux density [PFD, 2400 μEmol/(m 2·s)]. Sixteen fatty acids were identified by gas chromatography showing that AA was the dominant fatty acid (33%-41%) followed by linoleic acid (17%-21%). AA content was closely investigated with respect to total fatty acids (TFA), ash free dry weight (AFDW) of cell mass as well as total culture content. These parameters were influenced significantly in a similar manner by culture growth phase, i.e., slightly decreasing in the lag period, gradually increasing in the logarithmic phase, becoming maximal at the early stationary phase, starting to decrease at the late stationary phase, sharply dropping at the decline phase. The increase in AA per culture volume during the logarithmic phase was not only associated with the increase in AFDW but also connected with a corresponding increase in AA/TFA, TFA/AFDW as well as AA/AFDW. The sharp decrease in AA content of the culture during the decline phase was mainly due to the decrease in AA/TFA, TFA/AFDW and AA/AFDW, although AFDW declined only a small extent. Maximal AA concentration, obtained at the early stationary phase, was 900 mg/L culture volume, and the average daily net increase of AA during 9 days logarithmic growth was 1.7 g/(m 2·day). Therefore, harvesting prior to the decline phase in a batch culture, or at steady state in continuous culture mode seems best for high AA production. The latter possibility was also further confirmed by continuous culture with 5 gradients of harvesting rate.
文摘Genetic comparison between Rhynchophorus ferrugineus (Coleoptera: Curculionidae: Rhynchophorinae) and other four Rhynchophorus spp. such as R. bilineatus, R. phoenicis, R. cruentatus and R. palmarum was investigated using partial sequences of Cytochrome c oxidase subunit I (COl) mitochondrial gene. The number ofpolymorphic sites ranged from 79 to 102 while the genetic distances ranged from 0.058 to 0.095. The number of polymorphic sites, genetic distances and phylogenetic relationships among R. ferrugineus and the other four tested species revealed that R.ferrugineus was more closely related to R. bilineatus while it was distantly related to R. palmarum. It is possible to rank the five tested species as follows: R.ferrugineus, R. bilineatus, R. phoenicis, R. cruentatus and R. palmarum. The result of this study is the first step of the revision of the uncertain taxonomic status and phylogenetic relationships among the Rhynchophorus genus. Further analysis should be performed using other Rhynchophorus species as well as other molecular markers.
文摘The report examines the evolution of computers from digital analogs through non-yon Neumann machines to quantum computers, which are also digital analogs. In the 60 years of digital analogs successfully developed at the Institute of Electromechanics of the USSR in Leningrad. An important stage in the development of non-classical multiprocessor machine performance and reliability has been the development of recursive machines, which was carried out at the Institute of Cybernetics led V.M.Glushkov and the Leningrad Institute of Aviation Instrumentation. The general approach to the synthesis is carried out through linguo- combinatorial modeling with structured uncertainty.
文摘An experiment was conducted and through distant hybridization a new promising forms of citruses were obtained. Namely, after hybridization of lemon Georgian and broad-leaved mandarin unshiu (mother components) with early-ripening trifoliata and a hybrid of citrus ichangensis--"Caucasus" (father components) a wide range of nucellar seedlings were obtained. It should be noted that nucellar seedlings of hybrid nature are practically closer to distant hybrids of sexual origin that are sharply inclined to the side of the mother component and produce good quality fruit. Unfortunately, such hybrids are either very rare or cannot be obtained at all. While, in the case of the study, through using new combinations in hybridization, the possibility of getting nucellar seedlings of the hybrid nature is much bigger. Distant hybridization turned out to be particularly interesting because of the polyembryony of citrus plants. Due to this, it gives opportunity to get new promising forms not only from the egg cell but from nucellar cells as well.
基金Shandong Provincial Key Project of TCM Science and Technology(Grant No.2021Z051)Shandong Medical and Health Science and Technology Development Program(Grant No.202102040972)supported by Binzhou Medical College Student Innovation and Entrepreneurship Training Program(Grant No.X202210440354).
文摘Qianjinba is primarily cultivated in the southern regions of China and finds extensive use in traditional Chinese medicine(TCM)for conditions such as rheumatism,arthralgia,and gynecological ailments.It has been officially recognized as a protected variety of TCM by the state.The aim of this study was to investigate the therapeutic potential of Qianjinba polysaccharide(QJBDT)in treating rheumatoid arthritis(RA)in mice,along with a preliminary exploration of its mechanisms for inhibiting RA in these animals.Kunming mice(KM)were randomly divided into several groups,including a normal group,a model group(LPS group),low-dose,medium-dose,and high-dose QJBDT groups,as well as a positive control group(TGP group),each consisting of 10 mice.To induce inflammation and create an RA model,type II collagen was injected into the right hind foot joint.Following a 7-day modeling period,various concentrations of QJBDT and the positive control drug total glycoside of peony were administered via gavage once a day for 21 consecutive days.Throughout the study,we monitored and recorded the mice's weight,measured foot swelling,and assessed the arthritis index on a weekly basis.We also conducted pathological examinations of joint tissues and analyzed the signal pathway of p38 mitogen-activated protein kinase(MAPK)as well as the protein expression of nuclear factor NF-κB in the mice’s right foot joint tissues.Additionally,we employed ELISA to detect the levels of interleukin-β(IL-β),IL-17,and tumor necrosis factor-α(TNF-α)in the mice’s serum.The results of this study revealed that QJBDT effectively reduced the degree of foot swelling and the arthritis index in collagen-induced arthritis mice while improving their weight loss(P<0.05).Furthermore,it alleviated the pathological damage observed in the mice’s joints.Notably,the expression of transcription factors p38 and NF-κB proteins was down-regulated(P<0.05),and the levels of inflammatory cytokines IL-β,IL-17,and TNF-αin the mice’s serum were decreased(P<0.05).In conclusion,this study demonstrated that polysaccharides could inhibit the expression of transcription factors p38 and NF-κB,reduce the production of inflammatory factors,and alleviate the progression of RA to a certain extent.
基金The Research Platform for the Project of the Application Basic Plan in Sichuan Province(Grant No.2014JY0113)the Project of Department of Science in Sichuan Province(Grant No.14ZA0003)
文摘Taking Terminalia chebula Retz. as the control product, the polyphenolic contents of the processed products in Tibetian, Rubia cordifolia L. processed Terminalia chebula Retz. and Euphorbia fischeriana Steud processed Terminalia chebula Retz. were analyzed by HPLC. Polyphenolic contents increased from 4.54% to 5.69% and 7.46%, respectively, which may lead to the change in their pharmacological effects.
基金supported by National Natural Science Foundation of China(Grant Nos.11071147,11431010 and 11371278)Natural Science Foundation of Shandong Province(Grant Nos.ZR2010AM003and ZR2013AL013)+1 种基金Shanghai Municipal Science and Technology Commission(Grant No.12XD1405000)Fundamental Research Funds for the Central Universities
文摘Let A = F [x, y] be the polynomial algebra on two variables x, y over an algebraically closed field F of characteristic zero. Under the Poisson bracket, A is equipped with a natural Lie algebra structure. It is proven that the maximal good subspace of A* induced from the multiplication of the associative commutative algebra A coincides with the maximal good subspace of A* induced from the Poisson bracket of the Poisson Lie algebra A. Based on this, structures of dual Lie bialgebras of the Poisson type are investigated. As by-products,five classes of new infinite-dimensional Lie algebras are obtained.
基金supported by the National Natural Science Foundation of China(20932006,91013007)the National Basic Research Program of China(973 Program)(2011CB965300)
文摘Cyclotides constitute a fascinating family of circular proteins containing ca.30 amino acid residues.They have a unique cyclic cysteine knot topology and exhibit remarkable thermal,chemical and enzymatic stabilities.These characteristics enable them to have a range of biological activities and promising pharmaceutical and agricultural applications.Here,we present a practical strategy for the chemical synthesis of cyclotides through the intramolecular ligation of fully unprotected peptide O-esters.This strategy involves the mild Fmoc solid-phase peptide synthesis of the peptide O-ester backbone,the head-to-tail cyclization of the cyclotide backbone by native chemical ligation,and the oxidative refolding to yield the natural knot protein.The simplicity and high efficiency of the strategy can be employed in the synthesis of artificial cyclotides for pharmaceutical applications.
基金Project supported by the National Natural Science Foundation of China(Nos.11231002,10971023)the Shanghai Natural Science Foundation(No.09ZR1402000)
文摘In this paper,the authors construct a φ-group for n submodules,which generalizes the classical K-theory and gives more information than the classical ones.This theory is related to the classification theory for indecomposable systems of n subspaces.