期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
多彩之石——欧泊
1
作者 郝雅萍 《中国宝玉石》 1991年第4期26-27,共2页
造物主對地球一向慷慨,使我們脚踏的土地里產生出各種各樣的奇珍異寶。鑽石、紅寶石、琥珀、黃晶、祖母綠、青金石、藍寶石、紫晶組成了自然界的赤、橙、黄、綠、青、藍、紫七色彩。它們以各自鮮艷的單色裝點着人類。
关键词 多彩石 欧泊
下载PDF
MHC polymorphism and disease resistance to Singapore grouper iridovirus(SGIV) in the orange-spotted grouper, Epinephelus coioides 被引量:2
2
作者 杨敏 魏京广 +3 位作者 李鹏飞 魏世娜 黄友华 秦启伟 《Science Bulletin》 SCIE EI CAS CSCD 2016年第9期693-699,共7页
Major histocompatibility complex (MHC) genes are critical members in both innate and adaptive immunity, and the association between their polymorphism and disease resistance has been reported in many teleosts. In th... Major histocompatibility complex (MHC) genes are critical members in both innate and adaptive immunity, and the association between their polymorphism and disease resistance has been reported in many teleosts. In the present study, we first investigated the genetic variation at the MHC II β gene in orange-spotted grouper (Epinephelus coioides) after a challenge with Singapore grouper iridovirus (SGIV). The results reveal that a high polymorphism level of the MHC II β gene (H = 1.000; K = 20.206; π=0.081) and at least three loci exist in grouper. The rate of dN/dS in the peptide-binding region (PBR) and non-PBR were both 〉1, suggesting the loci were evolving under positive selection. A high ratio of heterozygous individuals (37.26 %) and high rate of dN/dS were discovered, suggesting that both heterozygote advantage and frequency-dependent selection might result in the high polymorphism levels in MHC II β genes in grouper. A total of 33 MHC II β alleles were identified from 40 high-susceptibility (HS) and 40 high-re- sistance group (HR) individuals, and 15 alleles were used in the association analysis. Three alleles, EPCO-DBB*0302, EPCO-DBB*0307, EPCO-DBB*0603, and EPCO- DBB*1001 were significantly associated with resistance ability to SG1V, and the EPCO-DBB*0607 and EPCO-DBB*1303 alleles were associated with susceptibility (P 〈 0.05). To further confirm the association, another independent challenge experiment was performed. The result of association analysis in the verification test found that only EPCO-DBB*1001 alleles were significantly asso- ciated with resistance to SGIV (P 〈 0.05), while the other alleles showed no significance (P 〉 0.05) in the frequency distribution between HR and HS groups. Therefore, the EPCO-DBB* 1001 alleles could be used as a disease resis- tance-related MHC marker in the molecular marker-assisted selective breeding program of grouper. 展开更多
关键词 Orange-spotted grouper Majorhistocompatibility complex II β Singapore grouperiridovirus Disease resistance
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部