Objective To investigate the association between two polymorphisms of follicle stimulating hormone receptor （FSHR） gene and polycystic ovary syndrome （PCOS） susceptibility. Methods Case-control studies on relatio...Objective To investigate the association between two polymorphisms of follicle stimulating hormone receptor （FSHR） gene and polycystic ovary syndrome （PCOS） susceptibility. Methods Case-control studies on relationship of Thr307Ala and Asn680Ser polymorphisms in FSHR gene and PCOS susceptibility were searched from PubMed, ISI web of knowledge, EBSCO, and China National Knowledge Infrastructure （CNKI） databases up to March 21, 2013. The pooled odds ratio （OR） and 95% confidence interval （CO were calculated using fixed- or random-effect model based on heterogeneity test in 5 genotype models analyses. Results A total of 11 studies were included in the Meta-analysis. The random-effect analysis showed Asn680Ser was significantly associated with the reduced susceptibility to PCOS with dominant model （Asn/Asn＋Asn/Ser vs. Ser/Ser, OR=0.83, 95% CI： 0.69-1.00）, recessive model （Asn/Asn vs. Asn/Ser＋ Ser/Ser, OR=0.84, 95% CI： 0.72-0.98）, homozygote comparison （Ash/Ash vs. Ser/Ser, 0R=0.79, 95% CI： 0.63-0.98）, and the allele contrast （Asn vs. Ser, OR=0.87, 95% CI： 0.79-0.97） respectively（P=0.02, I2=56.0%）, being protective factors for PCOS. However, no significant associations were found between Thr307Ala and PCOS. Conclusion There might be a significant association between Asn680Ser polymorphism and PCOS.展开更多
In order to understand the influence of brittleness and confining stress on rock cuttability,the indentation tests were carried out by a conical pick on the four types of rocks.Then,the experimental results were utili...In order to understand the influence of brittleness and confining stress on rock cuttability,the indentation tests were carried out by a conical pick on the four types of rocks.Then,the experimental results were utilized to take regression analysis.The eight sets of normalized regression models were established for reflecting the relationships of peak indentation force(PIF)and specific energy(SE)with brittleness index and uniaxial confining stress.The regression analyses present that these regression models have good prediction performance.The regressive results indicate that brittleness indices and uniaxial confining stress conditions have non-linear effects on the rock cuttability that is determined by PIF and SE.Finally,the multilayer perceptual neural network was used to measure the importance weights of brittleness index and uniaxial confining stress upon the influence for rock cuttability.The results indicate that the uniaxial confining stress is more significant than brittleness index for influencing the rock cuttability.展开更多
Women have been stereotyped as better multitaskers when compared to their male counterparts. The purpose of this study is to investigate whether there are differences in gender performance when performing cognitive co...Women have been stereotyped as better multitaskers when compared to their male counterparts. The purpose of this study is to investigate whether there are differences in gender performance when performing cognitive combined tasks. Twenty-four graduate students （twelve females and twelve males） volunteered to participate in the study. The task requires participants to indicate when they perceive a change in the intensity of an auditory signal while simultaneously solving algebraic problems. Multivariate Analysis of Variance （MANOVA） results reveal no significant differences between genders when performing the combined tasks （p = 0.1831 and 2 = 0.7891） although the average number of false alarms made during the combined tasks by males is nearly 11% higher than the average number of false alarms made by females. However, （Multivariate Analysis of Variance） ANOVA results for the combined tasks show that males outperform females on the computational task while listening for changes in the auditory signal F（1, 22） - 5.09, p 〈 0.03, but there are no significant differences in their ability to detect noise intensity variation or in the number of false alarms made while multitasking. For the single task analysis the ANOVAs indicate no significant differences in signal detection task performance, computational task performance, or the number of false alarms made by males and females.展开更多
文摘Objective To investigate the association between two polymorphisms of follicle stimulating hormone receptor （FSHR） gene and polycystic ovary syndrome （PCOS） susceptibility. Methods Case-control studies on relationship of Thr307Ala and Asn680Ser polymorphisms in FSHR gene and PCOS susceptibility were searched from PubMed, ISI web of knowledge, EBSCO, and China National Knowledge Infrastructure （CNKI） databases up to March 21, 2013. The pooled odds ratio （OR） and 95% confidence interval （CO were calculated using fixed- or random-effect model based on heterogeneity test in 5 genotype models analyses. Results A total of 11 studies were included in the Meta-analysis. The random-effect analysis showed Asn680Ser was significantly associated with the reduced susceptibility to PCOS with dominant model （Asn/Asn＋Asn/Ser vs. Ser/Ser, OR=0.83, 95% CI： 0.69-1.00）, recessive model （Asn/Asn vs. Asn/Ser＋ Ser/Ser, OR=0.84, 95% CI： 0.72-0.98）, homozygote comparison （Ash/Ash vs. Ser/Ser, 0R=0.79, 95% CI： 0.63-0.98）, and the allele contrast （Asn vs. Ser, OR=0.87, 95% CI： 0.79-0.97） respectively（P=0.02, I2=56.0%）, being protective factors for PCOS. However, no significant associations were found between Thr307Ala and PCOS. Conclusion There might be a significant association between Asn680Ser polymorphism and PCOS.
基金Project(51904333) supported by the National Natural Science Foundation of China。
文摘In order to understand the influence of brittleness and confining stress on rock cuttability,the indentation tests were carried out by a conical pick on the four types of rocks.Then,the experimental results were utilized to take regression analysis.The eight sets of normalized regression models were established for reflecting the relationships of peak indentation force(PIF)and specific energy(SE)with brittleness index and uniaxial confining stress.The regression analyses present that these regression models have good prediction performance.The regressive results indicate that brittleness indices and uniaxial confining stress conditions have non-linear effects on the rock cuttability that is determined by PIF and SE.Finally,the multilayer perceptual neural network was used to measure the importance weights of brittleness index and uniaxial confining stress upon the influence for rock cuttability.The results indicate that the uniaxial confining stress is more significant than brittleness index for influencing the rock cuttability.
文摘Women have been stereotyped as better multitaskers when compared to their male counterparts. The purpose of this study is to investigate whether there are differences in gender performance when performing cognitive combined tasks. Twenty-four graduate students （twelve females and twelve males） volunteered to participate in the study. The task requires participants to indicate when they perceive a change in the intensity of an auditory signal while simultaneously solving algebraic problems. Multivariate Analysis of Variance （MANOVA） results reveal no significant differences between genders when performing the combined tasks （p = 0.1831 and 2 = 0.7891） although the average number of false alarms made during the combined tasks by males is nearly 11% higher than the average number of false alarms made by females. However, （Multivariate Analysis of Variance） ANOVA results for the combined tasks show that males outperform females on the computational task while listening for changes in the auditory signal F（1, 22） - 5.09, p 〈 0.03, but there are no significant differences in their ability to detect noise intensity variation or in the number of false alarms made while multitasking. For the single task analysis the ANOVAs indicate no significant differences in signal detection task performance, computational task performance, or the number of false alarms made by males and females.
