多针密刺法治疗肩凝症42例

目的:观察多针密刺法治疗肩凝症的临床疗效。方法:选取肩凝症患者42例,均采用多针密刺法治疗,留针30 min,每日1次,14 d为1个疗程。结果:临床治愈32例,显效10例,无效0例,总有效率为100%。结论:多针密刺法治疗肩凝症疗效显著。

IMPACTS OF PENETRATION THERAPY WITH HEAD ELECTRICAL ACUPUNCTURE ON PROLIFERATION OF NEURAL STEM CELLS IN SUBSTANTIA NIGRA OF RAT MODEL OF PARKINSON'S DISEASE

Objective To probe into the function mechanism of penetration therapy with head electrical acupuncture on Parkinson＇s disease. Methods Microinjection of 6-hydroxydopamin （6-OHDA） on the left cor- pus striatum was adopted to prepare rotation model of Parkinson^s disease in rat. Penetration therapy with head electrical acupuncture was administered in treatment. Normal group, sham-operation group, model group and penetration therapy group were set up. （1）lmmunohistochemical （IHC） method was used to test the morphology and count of positive cell of tyrosine hydroxylase （TH）. （2）RT-PCR technology was used to detect the expression of nestin mRNA of neural stem cell （NSC）. Results （1）Compared with model group, in pene- tration therapy group, the expressions of TH-positive neurons in immune response were increased in areal density （AD）, numerical density （ND） and integrating optic density （P〈0.05）. （2）Compared with model group, in penetration therapy group, the expression of nestin mRNA was increased （P〈0. 05）. Conclusion Penetration therapy with head electrical acupuncture promotes the proliferation of endogenous neural stem cells in substantia nigra of rat model of Parkinson＇s disease.

TREATMENT OF NINETY-FIVE CASES OF MULTIPLESCLEROSIS WITH ACUPUNCTURE

From December of 1998 to August of 2002, the author treated 95 cases of multiple sclerosis with acupuncture. The observation has confirmed that acupuncture is a very effective method for treating this disease, especially to sclerosis patients in the early stage; and furthermore it can slow down the development of the pathological conditions of the patients. Thus it is an important therapeutic method worthy of the choice by European and American clinical doctors.

EFFECT OF ELECTROACUPUNCTURE ON PLASMA ANGIOTENSIN-ALDOSTERONE AND ATRIAL NATRIURETIC POLYPEPTIDE IN RABBITS WITH ACUTE CEREBRAL INFARCTION

Objective: To observe the therapeutic effect of electroacupuncture (EA) on plasma angiotensin (Ang Ⅱ), aldosterone (ALD) and atrial natriuretic polypeptide (ANP) contents in experimental cerebral infarction rabbits for analyzing the underlying mechanism of acupuncture in ameliorating blood supply of the brain tissue. Methods: A total of 80 rabbits were randomized into control (n = 8), pseudo-operation (n = 24), model (n = 24) and EA (n = 24) groups. Cerebral infarction model was established by infusion of self-thrombus into the carotid artery. EA (1 mA, 2 Hz) was applied to 'Baihui'(百会 GV 20) and 'Shuigou'(水沟 GV 26) for 30 min, once every 12 hours. Plasma Ang Ⅱ, ALD and ANP contents were detected with radioimmunoassay method. In the later 3 groups, blood samples were taken at 6 h, 24 h and 48 h after cerebral ischemia. Results: Compared with control and pseudo-operation groups, Ang Ⅱ and ALD contents of model group at 6 h, 24 h and 48 h after cerebral ischemia increased significantly while plasma ANP of the 3 time-courses of model group decreased considerably (P<0.01). In comparison with model group, results showed that Ang-Ⅱ and ALD contents of EA group decreased significantly whereas ANP level of EA group increased strikingly (P<0.01). Conclusion: Electroacupuncture has the effects of raising plasma ANP level and lowering plasma Ang-Ⅱ and ALD in cerebral infarction rabbits.

Analysis of acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome based on data mining

Objective:To analyze the meridian and acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome (PCOS) by data mining technique,for exploring acupoints that could be effective for PCOS and providing suggestion and reference in selecting acupoints for the acupuncture-moxibustion treatment of PCOS.Methods:Literatures related to the acupuncture-moxibustion treatment of PCOS published before April 2018 were collected.By a self-made data mining program developed using Microsoft Excel 2007,a database of acupuncture-moxibustion treatment of PCOS was then established.The correlation analysis was performed for the frequency of use of acupoints and acupoint groups.Cluster analysis was also conducted.Results:A total of 92 articles were recruited finally.Sanyinjiao (SP 6),Conception Vessel and chest-abdomen region ranked the top on the list of the most frequently used acupoints,meridians and regions,respectively.Correlation analysis showed that the acupoint group with the highest confidence was Sanyinjiao (SP 6) and Zusanli (ST 36),and the group with the highest support was Sanyinjiao (SP 6) and Guanyuan (CV 4).Cluster analysis revealed five effective clusters:Guanyuan (CV 4) and Sanyinjiao (SP 6);Zhongwan (CV 12) and Tianshu (ST 25);Zhongji (CV 3),Zusanli (ST 36) and Qihai (CV 6);Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29);Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20).Conclusion:According to the confidence and support report,Sanyinjiao (SP 6) and Zusanli (ST 36) or Sanyinjiao (SP 6) and Guanyuan (CV 4) are recommended in acupuncture-moxibustion treatment of PCOS,with adjunct points selected for different patterns,e.g.Zhongwan (CV 12) and Tianshu (ST 25) for tonifying spleen and expelling dampness;Zhongji (CV 3) and Qihai (CV 6) for supplementing qi and cultivating blood;Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29) for tonifying kidney and dissolving stasis;Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20) for tonifying kidney and spleen and regulating liver.

Acupuncture Treatment for Spontaneous Polyhidrosis

Objective： To compare the therapeutic effects of acupuncture and western medicine on spontaneous polyhidrosis. Methods： Acupuncture at Huatuojiaji points was used to treat 30 cases of spontaneous polyhidrosis and the western medicine was used to treat 26 cases for comparison. Results： The total effective rate of the former was 96.7% and that of the latter 57.7%. The difference in therapeutic effect between the two groups was significant （P〈0.01）. Conclusion： The therapeutic effect of acupuncture at Huatuojiaji points on spontaneous nolyhidrosis was better than that of western medicine.

Acupuncture Treatment for 26 Cases of Polycystic Ovary Syndrome

Polycystic ovary syndrome （PCOS） is a commonly encountered disease in fertile women, clinically manifested by polymorphous comprehensive symptoms such as irregular menstruation, infertility, polytrichosis and obesity, and manifested by high levels of androgen, and no ovulation constantly shown by monophasic basal body temperature （BBT）. The therapeutic methods are medication for promoting ovulation and surgery, but, even certain therapeutic effect can be achieved, there is certain side effect and high cost. The author had treated 26 cases of PCOS by acupuncture. Now, the report is given in the following.

Clinical Observation on Tourette Syndrome Treated by Different Acupuncture Methods

Objective： To approach a better solution for enhancing the therapeutic results of acupuncture therapy in the treatment of Tourette syndrome, by observing the clinical results of combined scalp with body acupuncture and mono-body acupuncture. Methods： Fifty-seven patients were randomized into a treatment group （31 cases） and a control group （26 cases）. The patients in the treatment group all received combined scalp-body acupuncture treatment, while the patients in the control group were given mono-body acupuncture treatment, for I month as a treatment session. At the end of the third treatment session, the Yale Global Tic Severity Scale （YGTSS） would be compared between pre- and post-treatment. Results： In the treatment group, 2 patients were clinically cured, 4 showed markedly effective, 18 showed effective, and 7 failed, making a total therapeutic rate of 77.4%. In the control group, 0 were clinically cured, 3 showed markedly effective, 9 showed effective, 14 failed, making a total therapeutic rate of 46.2%. There was a significant difference between the two total therapeutic rates （P〈0.05）. Conclusion： The combination of scalp and body acupuncture had a better therapeutic result than the mono-body acupuncture therapy in the treatment of Tourette syndrome.

Mechanism Study on Acupuncture for Non-insulin Resistant Polycystic Ovary Syndrome

Objective： To investigate the action mechanism of acupuncture for non-insulin resistant polycystic ovary syndrome （PCOS）. Methods： A total of 46 cases with non-insulin resistant PCOS were randomly allocated into an observation group of 23 cases and a control group of 23 cases. Cases in the observation group were treated by needling bilateral Weiwanxiashu （Ex-B 3）, whereas those in the control group were treated by needling bilateral Sanyinjiao （SP 6）. After 3-month treatments, a comparison was made on the changes of ovulations rates, Follicle-stimulating hormone （FSH）, luteinizing hormone （LH）, testosterone （T）, fasting insulin and body mass index （BMI）. Results： There were statistical differences in ovulation rates and LH/FSH before and after the treatment in the observation group （P〈0.05）, along with a statistical difference in testosterone changes （P〈0.01）. There were also statistical differences in LH and LH/FSH before and after the treatment in the control group （P〉0.05）; however, there were no statistical differences in ovulation rates and testosterone changes （P〈0.05）. There was significant difference in testosterone changes between the two groups after the treatment （P〈0.01）, along with a statistical difference in ovulation rates between the two groups （P〈0.05）. However, there were no statistical differences in LH/FSH and BMI between the two groups. Conclusion： Needling Weiwanxiashu （Ex-B 3） and Sanyinjiao （SP 6） can both improve the endocrine disorder of patients with non-insulin resistant PCOS; however, needling Weiwanxiashu （Ex-B 3） can obtain a better result than Sanyinjiao （SP 6） in increasing the insulin sensitivity and preventing insulin resistance.

Clinical study of acupuncture combined with medication for the elderly with Alzheimer disease

Objective:To observe the impact of mind-regulating acupuncture plus donepezil on the cognitive ability,mean cerebral blood flow velocity,event-related potential P300,and activities of daily living(ADL)in the aged patients with Alzheimer disease(AD).Methods:Sixty senile AD patients were divided into a treatment group and a control group following the envelope method for random allocation,with 30 cases in each group.Based on the conventional treatment of the internal medicine,the control group received oral donepezil,and the treatment group received oral donepezil plus mind-regulating acupuncture.After 4-week treatment,the two groups were evaluated by the mini-mental state examination(MMSE),Alzheimer disease assessment scale-cognitive part(ADAS-Cog),and ADL;changes in P300 and the mean cerebral blood flow velocity were also observed.Results:Before treatment,there were no significant differences in the scores of MMSE,ADAS-Cog,or ADL between the two groups(P>0.05).The MMSE score increased after treatment in both groups and was notably higher in the treatment group than in the control group,showing intra-group and inter-group statistical significance(P<0.05).After treatment,the ADAS-Cog and ADL scores dropped in both groups and were markedly lower in the treatment group than in the control group,also showing intra-group and inter-group statistical significance(P<0.05).Compared with the same group before treatment,the latency of P300 was shortened and the amplitude was extended in both groups,all with statistical significance(P<0.05);the latency was shorter and the amplitude was larger in the treatment group than in the control group after treatment,presenting significant between-group differences(P<0.05).The mean blood flow velocity accelerated after the intervention in both groups,and the differences were statistically significant(P<0.05);the improvement in the treatment group was more notable than that in the control group(P<0.05).Conclusion:Mind-regulating acupuncture plus donepezil can regulate the latency and amplitude of P300,increase cerebral blood flow,and improve the learning and memory abilities of AD patients.

Treatment of 28 Cases of Tourette's Syndrome by Puncturing Back-Shu Points

Twenty-eight cases of Infantile Tourette＇s syndrome were treated by puncturing Back-Shu points. In 28 cases of the patients, the results showed cure in 6 cases, effect in 21 cases and failure in one case, and the total effective rate in 96.4%.

Discussion on the curative effect of acupuncture for polycystic ovarian syndrome

Discussion on the negative result of the paper ＂Effect of acupuncture and clomiphene in Chinese women with polycystic ovary syndrome： a randomized clinical trial＂ from Chinese experts were organized, and experts from Beijing, Nanjing, Chengdu who＇s major were clinical acupuncture, acupuncture research and gynecology have made their points. In-depth discussion were made by the experts from the perspective of confirmation of therapeutic program, selection of outcome indices, application of statistical analysis, the illustration of research results and clinical effects. The experts have pointed out that the negative result is commonly seen in medical research and the key point is to find out the defects of the trial so as to modify the research orientation and better serve the clinical practice.

Observation on the Curative Effect of Acupuncture on Child Tourette＇s Syndrome

To investigate the efficacy of earth-reinforcing and wood-reducing acupuncture tbr child Tourette＇s syndrome. Methods： Forty-five children with Yourette＇s syndrome were randomly allocated, according to a random number table, into an acupuncture group （23 cases） and a Western medicine group （22 cases）. Points Zhongwan （CV 12） and Siguan were selected in co-operation with acupuncture of other routine points in the acupuncture group. Haloperidol was orally administered for routine treatment in the Western medicine group. Results： The cure rate was 65.2% in the acupuncture group and 31.8% in the Western medicine group. There was a significant difference in cure rate between the two groups （P〈0.05）. Conclusion： Earth-reinforcing and wood-reducing acupuncture has an exact curative effect on child Tourette＇s syndrome.