The primary objective of landslide susceptibility mapping is the prediction of potential landslides in landslide-prone areas. The predictive power of a landslide susceptibility mapping model could be tested in an adja...The primary objective of landslide susceptibility mapping is the prediction of potential landslides in landslide-prone areas. The predictive power of a landslide susceptibility mapping model could be tested in an adjacent area of similar geo- environmental conditions to find out the reliability. Both the 2oo8 Wenchuan Earthquake and the 2o13 Lushan Earthquake occurred in the Longmen Mountain seismic zone, with similar topographical and geological conditions. The two earthquakes are both featured by thrust fault and similar seismic mechanism This paper adopted the susceptibility mapping model of co-seismic landslides triggered by Wenchuan earthquake to predict the spatial distribution of landslides induced by Lushan earthquake. Six influencing parameters were taken into consideration: distance from the seismic fault, slope gradient, lithology, distance from drainage, elevation and Peak Ground Acceleration (PGA). The preliminary results suggested that the zones with high susceptibility of co- seismic landslides were mainly distributed in the mountainous areas of Lushan, Baoxing and Tianquan counties. The co-seismic landslide susceptibility map was completed in two days after the quake and sent to the field investigators to provide guidance for rescue and relief work. The predictive power of the susceptibility map was validated by ROC curve analysis method using 2o37 co-seismic landslides in the epicenter area. The AUC value of o.71o indicated that the susceptibility model derived from Wenchuan Earthquake landslides showed good accuracy inpredicting the landslides triggered by Lushan earthquake.展开更多
Objective:To investigate the therapeutic effects of dexamethasone,anisodamine and rhubarb(DAR) on endotoxin,tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and pancreatic damage in rat models of acute pancreatiti...Objective:To investigate the therapeutic effects of dexamethasone,anisodamine and rhubarb(DAR) on endotoxin,tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and pancreatic damage in rat models of acute pancreatitis(AP).Methods:The AP rat models were prepared and randomly assigned to AP group(n=10) and DAR group(n=10),while other healthy rats were assigned to the sham-operated group(n=10).The rats were euthanized at 6 h after operation,and then the serum levels of endotoxin,TNF-α,IL-6 and histology of pancreas were determined as the indexes of therapeutic effects.Results:At 6 h after operation,serum levels of endotoxin,TNF-α and IL-6,and pancreatic damage were significantly increased in AP group compared with those in sham-operated group(P<0.01).Compared with the AP group,DAR therapy remarkably attenuated the endotoxin,TNF-α,IL-6 levels and reduced pancreatic damage(P<0.05).Conclusion:The inhibition of pancreatic damage by DAR in rats with AP might contribute,in part at least,to the amelioration of pancreatic inflammation.The present study provides beneficial evidence that DAR may be useful in the treatment of AP model of rats.展开更多
Coulomb stress changes associated with strong earthquakes occurring since 1484 in Hebei Province,China are investigated. The North China block has had many large historical earthquakes and some damaging earthquakes in...Coulomb stress changes associated with strong earthquakes occurring since 1484 in Hebei Province,China are investigated. The North China block has had many large historical earthquakes and some damaging earthquakes in the past century,including the 1976 Tangshan earthquake (M =7.8) . The study area and the adjacent areas of the province comprise the most active seismic fault zones and suffer from both strong and frequent events. The North China Block,which includes the Ordos plateau and the North China plain,is part of the Archean Sino-Lorean craton and one of the most active seismic regions in the world. Its movement is accommodated on major strike-slip intraplate fault zones that strike in the E-W direction. The faults in the study area contribute to the complexity of the stress field. Seismic hazard assessment in this region is attempted by calculating the change of the Coulomb failure function ( ΔCFF) arising from both the coseismic slip of strong events (MS≥6.5) and the stress built up by continuous tectonic loading on major regional faults. At every step of the stress evolutionary model an examination of possible triggering of each next strong event is made and the model finally puts in evidence that the fault segments that are apt to fail in an impending strong event,thus providing future seismic hazard evaluation. In this paper,the results of ΔCFF for Zhangjiakou fault, Xiadian fault and Langfang fault have been shown as examples to express the possiblity of generating future seismic hazard.展开更多
基金supported by the National Basic Research Program"973"Project of the Ministry of Science and Technology of the People’s Republic of China(GrantNo.2013CB733202)theNational Key Technology R&D Program(Grant No.2011BAK12B01)+1 种基金the Young Foundation of NationalNatural Science of China(Grant No.41202210)the National Science Fund for DistinguishedYoung Scholars(Grant No.41225011)
文摘The primary objective of landslide susceptibility mapping is the prediction of potential landslides in landslide-prone areas. The predictive power of a landslide susceptibility mapping model could be tested in an adjacent area of similar geo- environmental conditions to find out the reliability. Both the 2oo8 Wenchuan Earthquake and the 2o13 Lushan Earthquake occurred in the Longmen Mountain seismic zone, with similar topographical and geological conditions. The two earthquakes are both featured by thrust fault and similar seismic mechanism This paper adopted the susceptibility mapping model of co-seismic landslides triggered by Wenchuan earthquake to predict the spatial distribution of landslides induced by Lushan earthquake. Six influencing parameters were taken into consideration: distance from the seismic fault, slope gradient, lithology, distance from drainage, elevation and Peak Ground Acceleration (PGA). The preliminary results suggested that the zones with high susceptibility of co- seismic landslides were mainly distributed in the mountainous areas of Lushan, Baoxing and Tianquan counties. The co-seismic landslide susceptibility map was completed in two days after the quake and sent to the field investigators to provide guidance for rescue and relief work. The predictive power of the susceptibility map was validated by ROC curve analysis method using 2o37 co-seismic landslides in the epicenter area. The AUC value of o.71o indicated that the susceptibility model derived from Wenchuan Earthquake landslides showed good accuracy inpredicting the landslides triggered by Lushan earthquake.
基金Supported by the Science and Technology Foundation of Shaanxi [2006K14-G2 (1)]
文摘Objective:To investigate the therapeutic effects of dexamethasone,anisodamine and rhubarb(DAR) on endotoxin,tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and pancreatic damage in rat models of acute pancreatitis(AP).Methods:The AP rat models were prepared and randomly assigned to AP group(n=10) and DAR group(n=10),while other healthy rats were assigned to the sham-operated group(n=10).The rats were euthanized at 6 h after operation,and then the serum levels of endotoxin,TNF-α,IL-6 and histology of pancreas were determined as the indexes of therapeutic effects.Results:At 6 h after operation,serum levels of endotoxin,TNF-α and IL-6,and pancreatic damage were significantly increased in AP group compared with those in sham-operated group(P<0.01).Compared with the AP group,DAR therapy remarkably attenuated the endotoxin,TNF-α,IL-6 levels and reduced pancreatic damage(P<0.05).Conclusion:The inhibition of pancreatic damage by DAR in rats with AP might contribute,in part at least,to the amelioration of pancreatic inflammation.The present study provides beneficial evidence that DAR may be useful in the treatment of AP model of rats.
基金funded by the project of "Strong Motion Records in the Seismic Resistance of the Tangshan Region ( No. 11276905D) ",Department of Science and Technology of Hebei Province,China
文摘Coulomb stress changes associated with strong earthquakes occurring since 1484 in Hebei Province,China are investigated. The North China block has had many large historical earthquakes and some damaging earthquakes in the past century,including the 1976 Tangshan earthquake (M =7.8) . The study area and the adjacent areas of the province comprise the most active seismic fault zones and suffer from both strong and frequent events. The North China Block,which includes the Ordos plateau and the North China plain,is part of the Archean Sino-Lorean craton and one of the most active seismic regions in the world. Its movement is accommodated on major strike-slip intraplate fault zones that strike in the E-W direction. The faults in the study area contribute to the complexity of the stress field. Seismic hazard assessment in this region is attempted by calculating the change of the Coulomb failure function ( ΔCFF) arising from both the coseismic slip of strong events (MS≥6.5) and the stress built up by continuous tectonic loading on major regional faults. At every step of the stress evolutionary model an examination of possible triggering of each next strong event is made and the model finally puts in evidence that the fault segments that are apt to fail in an impending strong event,thus providing future seismic hazard evaluation. In this paper,the results of ΔCFF for Zhangjiakou fault, Xiadian fault and Langfang fault have been shown as examples to express the possiblity of generating future seismic hazard.