Isotopic tracers and water quality indicators (TDS (Total Dissolved Solid), Cl^- and NO3^-contents) were used to characterize the recharge and control of the quality of groundwater in the alluvial aquifer beneath ...Isotopic tracers and water quality indicators (TDS (Total Dissolved Solid), Cl^- and NO3^-contents) were used to characterize the recharge and control of the quality of groundwater in the alluvial aquifer beneath of the N'djamena city. For this study, a total of 92 waters samples were taken and this included 67 wells, 21 pumps and 4 surface waters. Some groundwater has 6180 and 62H values close to those of the city of N'djamena and/or the Chad river rains. However, all sampled points are below the Global Meteoric Water Line reflecting their evaporated characters. The interpretation of the isotopic tracers highlights that the recharge of the analyzed ground waters may result from two major mechanisms: (1) direct infiltration of local precipitation; (2) lateral inflow of river waters. The upper aquifer is the most vulnerable to pollution, especially during the recharge period. This pollution is due to the leaching of soils during the rainy season and the rise of the groundwater level which accompanies the overflowing of the Chad and causes the leaching of the polluted horizons of the unsaturated zone. In contrast, the lower aquifer has acceptable concentrations of solutes.展开更多
In the present study expression of estrogen receptor subtype -alpha (ERalpha) and -beta (ERbeta) in the cerebral cortex, cerebellum, and olfactory bulb was investigated and compared between neonatal (1 to approximatel...In the present study expression of estrogen receptor subtype -alpha (ERalpha) and -beta (ERbeta) in the cerebral cortex, cerebellum, and olfactory bulb was investigated and compared between neonatal (1 to approximately 3-days-old) and adult (250 to approximately 350 g) rats, using reverse transcription-polymerase chain reaction (RT-PCR). No ERalpha transcripts were detectable in the adult cerebellum and olfactory bulb, whereas very weak expression of ERalpha was present in the adult cerebral cortex. No significant difference in ERbeta transcripts was detectable between the neonatal and adult rats. While transcripts for both ER subtypes were co-expressed in these brain areas of neonatal rats, although ERalpha expression was significantly weaker than ERbeta. Even in the cerebral cortex known to contain both ER subtypes in adult rats, ERalpha transcripts in neonatal rats were much higher than in adult. These observations provide evidence for the existence of different expression patterns of ERalpha/ERbeta transcripts in these three brain areas between the neonatal and adult rats, suggesting that each ER subtype may play a distinct role in the regulation of differentiation, development, and functions of the brain by estrogen.展开更多
Blocking is a large-scale, mid-latitude atmospheric anticyclone that splits the westerly into two jets and has a profound effect on local and regional climates. This study examined the seasonal, interannual, and decad...Blocking is a large-scale, mid-latitude atmospheric anticyclone that splits the westerly into two jets and has a profound effect on local and regional climates. This study examined the seasonal, interannual, and decadal variability of the Atlantic and Pacific blocking anticyclones in the Northern Hemisphere based on the National Centers for Environmental Prediction (NCEP)/National Center for Atmospheric Research (NCAR) reanalysis data between 1958 and 1999. The preferred blocking region during these forty-two years was located over the Atlantic. Most blocking anticyclones over the Atlantic occurred in spring, while most of those over the Pacific occurred in winter. Similar two-to four-year and eleven-year oscillations were found for both the Atlantic and Pacific blocks by using wavelet analysis. The dominant mode for the Pacific blocks is decadal variation, while for the Atlantic blocks the predominant one is interannual variation with a period of about three years. The frequencies of the Pacific and Atlantic blocks varied almost in phase on interannual time scales except during the period of 1965-1977, and frequencies were out of phase on decadal time scale throughout the forty-two years.展开更多
This paper examines the distribution and structure of populations of a medicinal and culinary herb native to Armenia. As one of the first countries to join the Convention on Biological Diversity (CBD), Armenia has a...This paper examines the distribution and structure of populations of a medicinal and culinary herb native to Armenia. As one of the first countries to join the Convention on Biological Diversity (CBD), Armenia has a strong interest in assessing the biodiversity of its native flora and identifying threats to the conservation of these species, particularly those with economic value. Only limited information, however, is available at this time on the genetic biodiversity, population location, structure and size, and conservation status of most of these species. This paper reports the results of five consecutive years of field studies conducted in Armenia to 1) re-locate native populations of the important medicinal and culinary herb, Origanum vulgare L., 2) locate new populations, and 3) assess the growth pattern and dynamics of the populations. The quadrat sampling technique was used to identify key elements that determined population size and abundance. GPS maps of present and past population distributions were created. Particular habitat and environmental factors were identified as crucial to predicting the future conditions of these populations under the impact of global climate change. The research provides a baseline dataset that can be used for the development of further conservation strategies of this important medicinal and culinary species in Armenia.展开更多
OBJECTIVE: To evaluate the anti-infectious efficacy of essential oil extracted from Caoguo(Fructus Tsaoko).METHODS: Minimum inhibitory concentrations(MICs) against clinical isolates of three extracts andthe essential ...OBJECTIVE: To evaluate the anti-infectious efficacy of essential oil extracted from Caoguo(Fructus Tsaoko).METHODS: Minimum inhibitory concentrations(MICs) against clinical isolates of three extracts andthe essential oil from Caoguo(Fructus Tsaoko) were determined by the agar dilution method. The anti-infectious efficacy of the essential oil was evaluated using a mouse peritonitis model which was infected with Staphylococcus aureus or Escherichia coli. The chemical components of the essential oil were identified.RESULTS: The results showed that the essential oil exhibited strong antibacterial activity in vitro, with MICs ranging from 22.49 to 1438.91 μg/m L. The results of in vivo anti-infectious efficacy showed that the Caoguo(Fructus Tsaoko) essential oil can protect the mice from Staphylococcus aureus or Escherichia coli infection. The compositions of the essential oil and relative component percentages were examined. A total of 32 compounds, were identified. The major compounds of essential oil were 1,8-cineole(25.92%) and geraniol(13.69%).CONCLUSION: Our findings suggest that Caoguo(Fructus Tsaoko) essential oil has broad-spectrum antibacterial properties. It warrants further investigation as an antibacterial agent targeting some bacterium with multi-drug resistance.展开更多
文摘Isotopic tracers and water quality indicators (TDS (Total Dissolved Solid), Cl^- and NO3^-contents) were used to characterize the recharge and control of the quality of groundwater in the alluvial aquifer beneath of the N'djamena city. For this study, a total of 92 waters samples were taken and this included 67 wells, 21 pumps and 4 surface waters. Some groundwater has 6180 and 62H values close to those of the city of N'djamena and/or the Chad river rains. However, all sampled points are below the Global Meteoric Water Line reflecting their evaporated characters. The interpretation of the isotopic tracers highlights that the recharge of the analyzed ground waters may result from two major mechanisms: (1) direct infiltration of local precipitation; (2) lateral inflow of river waters. The upper aquifer is the most vulnerable to pollution, especially during the recharge period. This pollution is due to the leaching of soils during the rainy season and the rise of the groundwater level which accompanies the overflowing of the Chad and causes the leaching of the polluted horizons of the unsaturated zone. In contrast, the lower aquifer has acceptable concentrations of solutes.
文摘In the present study expression of estrogen receptor subtype -alpha (ERalpha) and -beta (ERbeta) in the cerebral cortex, cerebellum, and olfactory bulb was investigated and compared between neonatal (1 to approximately 3-days-old) and adult (250 to approximately 350 g) rats, using reverse transcription-polymerase chain reaction (RT-PCR). No ERalpha transcripts were detectable in the adult cerebellum and olfactory bulb, whereas very weak expression of ERalpha was present in the adult cerebral cortex. No significant difference in ERbeta transcripts was detectable between the neonatal and adult rats. While transcripts for both ER subtypes were co-expressed in these brain areas of neonatal rats, although ERalpha expression was significantly weaker than ERbeta. Even in the cerebral cortex known to contain both ER subtypes in adult rats, ERalpha transcripts in neonatal rats were much higher than in adult. These observations provide evidence for the existence of different expression patterns of ERalpha/ERbeta transcripts in these three brain areas between the neonatal and adult rats, suggesting that each ER subtype may play a distinct role in the regulation of differentiation, development, and functions of the brain by estrogen.
文摘Blocking is a large-scale, mid-latitude atmospheric anticyclone that splits the westerly into two jets and has a profound effect on local and regional climates. This study examined the seasonal, interannual, and decadal variability of the Atlantic and Pacific blocking anticyclones in the Northern Hemisphere based on the National Centers for Environmental Prediction (NCEP)/National Center for Atmospheric Research (NCAR) reanalysis data between 1958 and 1999. The preferred blocking region during these forty-two years was located over the Atlantic. Most blocking anticyclones over the Atlantic occurred in spring, while most of those over the Pacific occurred in winter. Similar two-to four-year and eleven-year oscillations were found for both the Atlantic and Pacific blocks by using wavelet analysis. The dominant mode for the Pacific blocks is decadal variation, while for the Atlantic blocks the predominant one is interannual variation with a period of about three years. The frequencies of the Pacific and Atlantic blocks varied almost in phase on interannual time scales except during the period of 1965-1977, and frequencies were out of phase on decadal time scale throughout the forty-two years.
文摘This paper examines the distribution and structure of populations of a medicinal and culinary herb native to Armenia. As one of the first countries to join the Convention on Biological Diversity (CBD), Armenia has a strong interest in assessing the biodiversity of its native flora and identifying threats to the conservation of these species, particularly those with economic value. Only limited information, however, is available at this time on the genetic biodiversity, population location, structure and size, and conservation status of most of these species. This paper reports the results of five consecutive years of field studies conducted in Armenia to 1) re-locate native populations of the important medicinal and culinary herb, Origanum vulgare L., 2) locate new populations, and 3) assess the growth pattern and dynamics of the populations. The quadrat sampling technique was used to identify key elements that determined population size and abundance. GPS maps of present and past population distributions were created. Particular habitat and environmental factors were identified as crucial to predicting the future conditions of these populations under the impact of global climate change. The research provides a baseline dataset that can be used for the development of further conservation strategies of this important medicinal and culinary species in Armenia.
基金Supported by the Fund of Department of Science and Technology of Sichuan Province(Molecular Mechanism of Caoguo Oil Reversing Multi-Drug Resistance of MRSA by Regulating Mec A Gene Expression Through Mecr1-Meci-Meca Resistance Pathway,No.2016JY0014Study on Pharmacodynamics and Mechanism of Caoguo in Treatment of Infectious Diseases,No.2016FZ0068)+3 种基金Sichuan Province Office of Education(Bacterial Infection and Laboratory Diagnosis,No.16TD0027Research on the Antibacteria Mechanism of Geraniol,No.15ZB0238)the Open-Study Funds of State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine,Chengdu University of Traditional Chinese Medicine(the Activity and Mechanism of Caoguo Oil Reversing Multi-Drug Resistance of MRSA)the Scientific Research Fund of Chengdu Medical College(the Study on the Synergistic Effect and the Mechanism of Geraniol andβ-lactam Antibiotics against Methicillin-resistant Staphylococcus Aureus,No.CYZ15-02)
文摘OBJECTIVE: To evaluate the anti-infectious efficacy of essential oil extracted from Caoguo(Fructus Tsaoko).METHODS: Minimum inhibitory concentrations(MICs) against clinical isolates of three extracts andthe essential oil from Caoguo(Fructus Tsaoko) were determined by the agar dilution method. The anti-infectious efficacy of the essential oil was evaluated using a mouse peritonitis model which was infected with Staphylococcus aureus or Escherichia coli. The chemical components of the essential oil were identified.RESULTS: The results showed that the essential oil exhibited strong antibacterial activity in vitro, with MICs ranging from 22.49 to 1438.91 μg/m L. The results of in vivo anti-infectious efficacy showed that the Caoguo(Fructus Tsaoko) essential oil can protect the mice from Staphylococcus aureus or Escherichia coli infection. The compositions of the essential oil and relative component percentages were examined. A total of 32 compounds, were identified. The major compounds of essential oil were 1,8-cineole(25.92%) and geraniol(13.69%).CONCLUSION: Our findings suggest that Caoguo(Fructus Tsaoko) essential oil has broad-spectrum antibacterial properties. It warrants further investigation as an antibacterial agent targeting some bacterium with multi-drug resistance.