The present work contributed to a new developed production method for enhancing the quality of isoamylene （IA） by adding a small amount of tertiary amyl alcohol （TAA） to the catalyst of strong acid cation exchange...The present work contributed to a new developed production method for enhancing the quality of isoamylene （IA） by adding a small amount of tertiary amyl alcohol （TAA） to the catalyst of strong acid cation exchange resin. TAA improved the selectivity of 2-methyl-2-butene （2M2B） at a high conversion level for the isomerization of IA. Compared with the other results from the current IA units, the conversion of 2-methyl- 1-butene （2M1B）, the mass ratio of 2M2B to 2M1B and the selectivity of 2M2B were increased from 0.5474, 7.32 and 0.6864 to 0.72, 12 and 0.95, respectively, while the dimers content in the products decreased from 4.38% to below 1.0%. Optimized conditions for IA isomerization consisted of temperature between 28 and 33℃ and system pressure of 0.5 MPa, weight hourly space velocity of 8.0 h-1 with TAA mass fraction of 0.7%-0.9% in raw material. The results in lab supported bases for the developed process in industrial application which was later proved to be successful. In addition, a possible mechanism of the isomerization process was speculated to propose a key step of water formation in the TAA-added isomerization process and a verified experiment was conducted to support this speculation.展开更多
Hydraulic fracturing is one of the efficient means for the abundant low-permeability CBM （coal-bed methane） reserves in China, however, due to the unique features of coal seams （i.e., low temperature, strong adsorp...Hydraulic fracturing is one of the efficient means for the abundant low-permeability CBM （coal-bed methane） reserves in China, however, due to the unique features of coal seams （i.e., low temperature, strong adsorption and abnormal development of natural fracture systems） as compared with the conventional reservoirs, the fractures propagate is difficult and the risk of damage to coal seam itself and the hydraulic fractures would be extremely high in the course of fracturing. As a result, losses would be suffered on the post-frac production of CBM wells.With the mean of numerical simulation, in this paper, the main factors have impact on the post-frac results as well as the extent to which the impact is brought were researched, and the technical solutions for the improvement of the fracturing performance was put forwards.展开更多
The fabrication of functional microcarriers capable of achieving in vivo-like three-dimensional cell culture is important for many tissue engineering applications. Here,inspired by the structure of Buddha beads, which...The fabrication of functional microcarriers capable of achieving in vivo-like three-dimensional cell culture is important for many tissue engineering applications. Here,inspired by the structure of Buddha beads, which are generally composed of moveable beads strung on a rope, we present novel cell microcarriers with controllable macropores and heterogeneous microstructures by using a capillary array microfluidic technology. Microfibers with a string of moveable and releasable microcarriers could be achieved by an immediate gelation reaction of sodium alginate spinning and subsequent polymerization of cell-dispersed gelatin methacrylate emulsification. The sizes of the microcarriers and their inner macropores could be well tailored by adjusting the flow rates of the microfluidic phases; this was of great importance in guaranteeing a sufficient supply of nutrients during cell culture. In addition, by infusing multiple cell-dispersed pregel solutions into the capillaries, the microcarriers with spatially heterogeneous cell encapsulations for mimicking physiological structures and functions could also be achieved.展开更多
文摘The present work contributed to a new developed production method for enhancing the quality of isoamylene （IA） by adding a small amount of tertiary amyl alcohol （TAA） to the catalyst of strong acid cation exchange resin. TAA improved the selectivity of 2-methyl-2-butene （2M2B） at a high conversion level for the isomerization of IA. Compared with the other results from the current IA units, the conversion of 2-methyl- 1-butene （2M1B）, the mass ratio of 2M2B to 2M1B and the selectivity of 2M2B were increased from 0.5474, 7.32 and 0.6864 to 0.72, 12 and 0.95, respectively, while the dimers content in the products decreased from 4.38% to below 1.0%. Optimized conditions for IA isomerization consisted of temperature between 28 and 33℃ and system pressure of 0.5 MPa, weight hourly space velocity of 8.0 h-1 with TAA mass fraction of 0.7%-0.9% in raw material. The results in lab supported bases for the developed process in industrial application which was later proved to be successful. In addition, a possible mechanism of the isomerization process was speculated to propose a key step of water formation in the TAA-added isomerization process and a verified experiment was conducted to support this speculation.
文摘Hydraulic fracturing is one of the efficient means for the abundant low-permeability CBM （coal-bed methane） reserves in China, however, due to the unique features of coal seams （i.e., low temperature, strong adsorption and abnormal development of natural fracture systems） as compared with the conventional reservoirs, the fractures propagate is difficult and the risk of damage to coal seam itself and the hydraulic fractures would be extremely high in the course of fracturing. As a result, losses would be suffered on the post-frac production of CBM wells.With the mean of numerical simulation, in this paper, the main factors have impact on the post-frac results as well as the extent to which the impact is brought were researched, and the technical solutions for the improvement of the fracturing performance was put forwards.
基金supported by the National Natural Science Foundation of China(21473029 and 51522302)the NSAF Foundation of China(U1530260)+3 种基金the Natural Science Foundation of Jiangsu(BK20140028)the Program for New Century Excellent Talents in Universitythe Scientific Research Foundation of Southeast Universitythe Scientific Research Foundation of Graduate School of Southeast University
文摘The fabrication of functional microcarriers capable of achieving in vivo-like three-dimensional cell culture is important for many tissue engineering applications. Here,inspired by the structure of Buddha beads, which are generally composed of moveable beads strung on a rope, we present novel cell microcarriers with controllable macropores and heterogeneous microstructures by using a capillary array microfluidic technology. Microfibers with a string of moveable and releasable microcarriers could be achieved by an immediate gelation reaction of sodium alginate spinning and subsequent polymerization of cell-dispersed gelatin methacrylate emulsification. The sizes of the microcarriers and their inner macropores could be well tailored by adjusting the flow rates of the microfluidic phases; this was of great importance in guaranteeing a sufficient supply of nutrients during cell culture. In addition, by infusing multiple cell-dispersed pregel solutions into the capillaries, the microcarriers with spatially heterogeneous cell encapsulations for mimicking physiological structures and functions could also be achieved.
