A 43-year-old female with a 3-month history of paroxysmal irritating cough presented progressive chest tightness and shortness of breath.Laboratory data showed elevated carcino-embryonic antigen(CEA).Further imaging s...A 43-year-old female with a 3-month history of paroxysmal irritating cough presented progressive chest tightness and shortness of breath.Laboratory data showed elevated carcino-embryonic antigen(CEA).Further imaging studies revealed a soft tissue mass shadow was in right middle lobe lung with mediastinal and sub-carinal lymph nodes enlarged.Biopsy diagnosis:moderately and poorly differentiated adenocarcinoma of the lung.Clinical diagnosis:central non-small cell lung cancer(NSCLC) of right middle lobe(CIVT4N2M1),lung adenocarcinoma G2-3,malignant pleural effusion,pericardial effusion,hilar and mediastina lymph node metastases.After 4 cycles of endostar plus GC therapy,imaging studies revealed showed soft tissue mass in right middle lobe disappeared,and evaluation of short-term result was complete remission(CR).PFS has been seven months till now.Therefore,this report provided strong evidence that endostatin combined GC treatment for advanced NSCLC is safe and effective,which can prolong survival and improve quality of life.展开更多
Digital cable-stayed bridge maintenance and management system （DCBMS） was developed for the need of maintenance and management of long-span cable-stayed bridges. In this paper, the major functions and theoretical ap...Digital cable-stayed bridge maintenance and management system （DCBMS） was developed for the need of maintenance and management of long-span cable-stayed bridges. In this paper, the major functions and theoretical application of eight modules were systematically stated with the background of Harbin Songhua River cable-stayed bridge, which include data management module, inspection and measurement module, assessment module, finite dement analysis module, disease diagnosis and prediction module, maintenance module, query module and help module. By analyzing and calculating the data from manual inspection database, basic database and health monitoring subsystem, DCBMS can accomplish the functions like life prediction, disease diagnosis, comprehensive assessment, maintenance and management of bridges. Therefore, the maintenance and management of long-span cable-stayed bridges can be made digital, professional and scientific. By running this system, a real-time and specific technical guidance can be provided for the maintainers and managers of long- span cable-stayed bridges.展开更多
文摘A 43-year-old female with a 3-month history of paroxysmal irritating cough presented progressive chest tightness and shortness of breath.Laboratory data showed elevated carcino-embryonic antigen(CEA).Further imaging studies revealed a soft tissue mass shadow was in right middle lobe lung with mediastinal and sub-carinal lymph nodes enlarged.Biopsy diagnosis:moderately and poorly differentiated adenocarcinoma of the lung.Clinical diagnosis:central non-small cell lung cancer(NSCLC) of right middle lobe(CIVT4N2M1),lung adenocarcinoma G2-3,malignant pleural effusion,pericardial effusion,hilar and mediastina lymph node metastases.After 4 cycles of endostar plus GC therapy,imaging studies revealed showed soft tissue mass in right middle lobe disappeared,and evaluation of short-term result was complete remission(CR).PFS has been seven months till now.Therefore,this report provided strong evidence that endostatin combined GC treatment for advanced NSCLC is safe and effective,which can prolong survival and improve quality of life.
基金Sponsored by the Research Fund for the Doctoral Program of Higher Education of China(Grant No.20050213008)Scientific and Technical Plan Item of Communications Department of Heilongjiang Province of China(Grant No.2004).
文摘Digital cable-stayed bridge maintenance and management system （DCBMS） was developed for the need of maintenance and management of long-span cable-stayed bridges. In this paper, the major functions and theoretical application of eight modules were systematically stated with the background of Harbin Songhua River cable-stayed bridge, which include data management module, inspection and measurement module, assessment module, finite dement analysis module, disease diagnosis and prediction module, maintenance module, query module and help module. By analyzing and calculating the data from manual inspection database, basic database and health monitoring subsystem, DCBMS can accomplish the functions like life prediction, disease diagnosis, comprehensive assessment, maintenance and management of bridges. Therefore, the maintenance and management of long-span cable-stayed bridges can be made digital, professional and scientific. By running this system, a real-time and specific technical guidance can be provided for the maintainers and managers of long- span cable-stayed bridges.
