皮脂腺痣并发乳头状汗管囊腺瘤及管状大汗腺腺瘤1例

1病例摘要 患者女，44岁。因左额部起皮疹并逐渐增大伴瘙痒44年，于2014年10月到我科就诊。患者于1970年出生时家人发现其左额部有一豌豆大黄褐色斑块，呈蜡样光泽，表面粗糙且无毛发生长，

皮脂腺痣并发基底细胞癌及管状乳头状大汗腺腺瘤

报告1例皮脂腺痣并发基底细胞癌及管状乳头状大汗腺腺瘤。患者男,43岁。因右侧头部斑块43年就诊。皮肤科检查:右侧头部见淡黄色丘疹、结节及疣状斑块,质软,边界清楚,局部见数个大小不等黑色结节。皮损组织病理检查示(1)切片右侧:表皮角化过度伴角化不全,真皮浅、中层可见大小不等的肿瘤细胞团块,部分和表皮相连,肿瘤细胞团块由基底样细胞组成,肿瘤团块周边细胞呈栅栏状排列并可见收缩间隙;(2)切片左侧:表皮角化过度、棘层肥厚,乳头瘤样增生,真皮浅、中层可见增生的皮脂腺及以淋巴细胞为主的炎性细胞浸润,真皮深层见大汗腺分布,形成较多管腔样结构,管腔内见大汗腺呈乳头状突入管腔。

管状大汗腺腺瘤

患者女，45岁。主诉：外阴肿物6年。现病史：患者6年前无明显诱因于左侧大阴唇内侧出现一肤色丘疹，随后丘疹缓慢增大，无破溃，偶有轻度瘙痒。于2010年9月来我科就诊。既往史、个人史、家族史：无特殊。

皮脂腺痣合并大汗腺囊腺瘤1例

皮脂腺痣常与其他皮肤附属器肿瘤并存,可同时合并大汗腺囊腺瘤,报告1例皮脂腺痣合并大汗腺囊腺瘤。

外分泌黏蛋白组织化生和大汗腺囊腺瘤相关

Mucinous metaplasia occurs uncommonly in cutaneous pathology, usually at specialized anatomic locations (genitalia, palms, and soles) and within restricted pathologic contexts (inflammation and trauma). Here, we report a unique case of eccrine mucinous metaplasia associated with an apocrine cystadenoma. A 13-year-old girl had an asymptomatic, 4-mm nodule on the chest. Histopathology demonstrated a typical apocrine cystadenoma in the upper and middle dermis. Adjacent to this lesion was a cluster of coiled eccrine secretory glands, of which the inner layer was almost entirely replaced by benign-appearing cells containing abundant, non-sulfated acid mucopolysaccharides. At 10 months’follow up, there was no recurrence. Our case demonstrates that, very uncommonly, mucinous metaplasia may be associated with a pathogenetically separate,adjacent proliferative adenomatous lesion, in this instance, an apocrine cystadenoma.

皮肤肿瘤

201312951333例皮肤恶性肿瘤回顾性分析/熊燕(三军大西南医院皮肤科),阎衡,齐燕…∥实用皮肤病学杂志.-2013,6(2).-77～791333例皮肤恶性肿瘤患者,男742例,女591例。965例临床与病理诊断相符(72.4%)。