Damp-heat karst mountainous areas are unique areas in terms of socialeconomic development, resource endowment and eco-environment in China, where natural resources are abundant,unique and diverse. However, fragile eco...Damp-heat karst mountainous areas are unique areas in terms of socialeconomic development, resource endowment and eco-environment in China, where natural resources are abundant,unique and diverse. However, fragile eco-environment, undeveloped economy and culture, and conflict of human and environment should not be ignored. In the research, a framework of integration of resource-development and environment-protection in damp-heat karst was designed on basis of resource and environment integration, which was applied to Daxin County in Guangxi Province. Furthermore, some integration models were proposed, including integration of development of characteristic agricultural resources and protection of eco-environment, integration of development of manganese ore resources and protection of eco-environment, integration of development of tourism resources and protection of ecoenvironment and integration of development of clean energy and protection of eco-environment.展开更多
Datong coal was extracted with CS2, n-hexane, benzene, methanol, acetone, tetrahydro-furan(THF) and THF/methanol(1:3,v/v) mixed solvent sequentially. The extracts were analyzed with GC/MS. It is presented that gr...Datong coal was extracted with CS2, n-hexane, benzene, methanol, acetone, tetrahydro-furan(THF) and THF/methanol(1:3,v/v) mixed solvent sequentially. The extracts were analyzed with GC/MS. It is presented that group seperation of soluble organic compounds in the coal can be achieved by fractionated extraction using different solvents. The results show that CS2 was effective for extracting arenes from the coal sample, n-Hexane extractable fraction from Datong coal mainly consists of n-alkanes. A great variety of oxygen-containing compounds are dominant in the components of methanol-soluble fraction. Acyclic isoprenoids, pentecyclic triterpanes and a series of cyclohexanes with long-chain alkyl-substitutes are detected in acetone-soluble fraction. Dicyclic aramatic hydrocarbons are identified in benzene-soluble fraction and 4-6 cyclic condensed aramatic hydrocarbons are identified in THF-soluble fraction. The molecular structures detection of 1,2-dichlorobenzene, 2,4-dibromophnol, 2,4,6-tribromophenol and 4-chlorobenzophenone firstly provide information for existence form of bromine and chlorine in coal.展开更多
Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE)...Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE). Analysis of the observation data showed that particle pollution was heavy in winter at Datong and that concentrations of most elements were high in the coarse range. Factor analysis (FA) results indicated that the soil and dust, coal combustion dust, and industry dust are main sources for atmospheric particles in winter at Datong. The enrichment factors of element concentrations showed that particle pollution at Datong impacts the down-wind region-Beijing-in the dust season.展开更多
The dominant patterns of the winter(December-February)surface air temperature anomalies(SATAs)over Central Asia(CA)are investigated in this study.The first two leading modes revealed by empirical orthogonal function(E...The dominant patterns of the winter(December-February)surface air temperature anomalies(SATAs)over Central Asia(CA)are investigated in this study.The first two leading modes revealed by empirical orthogonal function(EOF)analysis represent the patterns by explaining 74%of the total variance.The positive phase of EOF1 is characterized by a monopole pattern,corresponding to cold SATAs over CA,while the positive phase of EOF2 shows a meridional dipole pattern with warm and cold SATAs over northern and southern CA.EOF1 is mainly modulated by the negative phase of the Arctic Oscillation(AO)in the troposphere,and the negative AO phase may be caused by the downward propagation of the precursory anomalies of the stratospheric polar vortex.EOF2 is mainly influenced by the Ural blocking pattern and the winter North Atlantic Oscillation(NAO).The SATAs associated with EOF2 can be attributed to a dipole-like pattern of geopotential height anomalies over CA.The dipole-like pattern is mainly caused by the Ural blocking pattern,and the NAO can also contribute to the northern part of the dipole.展开更多
Measurements of seafloor asymmetry at about 360 000 pairs of conjugate points along 1250 profiles across the mid-Atlantic Ridge (MAR) provide new constraints on models for the upwelling of the buoyant asthenosphere. T...Measurements of seafloor asymmetry at about 360 000 pairs of conjugate points along 1250 profiles across the mid-Atlantic Ridge (MAR) provide new constraints on models for the upwelling of the buoyant asthenosphere. The sign and amplitude of the asymmetry vary systematically and are functions of the distance between the spreading center and the location of the inferred location of maximum regional buoyancy (LMRB) in the asthenosphere. The LMRB is a smooth line derived from the observed asymmetry and is more centered at the regional topographic high than the spreading center. These observations are best explained by active upwelling of the underlying buoyant asthenosphere rather than by pressure-release melting.展开更多
Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small...Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. Methods: Fifty patients with advanced NSCLC (stages III to IV), who had received therapies in our Center (Department of Biotherapy, Affiliated to Cancer Hospital of Shanxi Medical University, Taiyuan, China) from August 2008 to January 2010, were treated by DC-CIK + chemotherapy as the combined treatment group; fifty advanced NSCLC patients treated with chemotherapy at the same time served as controls. The immunologic function, short-term therapeutic effects, the 1-year survival rate, the life quality, the chemotherapy side effects were compared between the two groups, the safety and therapeutic effects of DC-CIK cells therapy were observed too. Results: There was no obvious change of subsets of T cells in peripheral blood before and after therapy in DC-CIK + chemotherapy group, and IFN-γ was improved after therapy in this group (P < 0.05); in chemotherapy alone group, the ratios of CD3+CD4+, CD3+CD8+, CD3-CD56+ cells and the secretion of IL-2, TNF-α decreased significantly after therapy (P < 0.05); the ratios of CD3+CD8+, CD3+CD56+ were improved after cell culture (P < 0.05). The disease control rate (DCR) of DC-CIK + chemotherapy group was higher than that in the chemotherapy alone group (78.0% vs 56.0%, P < 0.05); the 1-year survival rates of DC-CIK + chemotherapy group and chemotherapy alone group were 50% and 44% respectively, had no significant difference. Compared with chemotherapy alone group, the occurrence of chemotherapy side effects (including bone marrow suppression, nausea and vomiting, peripheral nerve toxicity) was less in the DC-CIK + chemotherapy group (P < 0.05). The physical and appetite were better in DC-CIK + chemotherapy group after therapy. Conclusion: To compare with simple chemotherapy, DC-CIK + chemotherapy for advanced NSCLC is safe and effective, and it can improve patients' life quality and remission rate, and prolong their survival time.展开更多
The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Prov...The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Province and tried to find the generation mechanisms of current non-balanced economic development of Shandong Province.And then approaches to regional development were put forward according to the theory of regional development pattern as a whole.展开更多
The issues of acid mine drainage (AMD) and heavy metals contamination in the metal sulfide mine in the add district were explored, through studying the acidification and the heavy metals distribution and evolution o...The issues of acid mine drainage (AMD) and heavy metals contamination in the metal sulfide mine in the add district were explored, through studying the acidification and the heavy metals distribution and evolution of groundwater in the black swan (BS) nickel sulfide mine (Western Australia). The groundwater samples were collected from the drilling holes situated in the vicinity of tailings storage facility (TSF) and in the background of the mine (away from TSF), respectively, and the pH and electric conductivity (Ec) were measured in site and the metal contents were analysed by ICP-MS and ICP-AES, quarterly in one hydrological year. The results disclose that the TSF groundwater is remarkably acidified (.pHmean=5, pHmin=3), and the average contents of heavy metals (Co, Cu, Zn, Cd) and Al, Mn are of 1-2 orders of magnitude higher in TSF groundwater than in background groundwater. It may be due to the percolation of tailings waste water from miU process, which leads the tailings to oxidize and the deep groundwater to acidify and contaminate with heavy metals. Besides, the heavy metals concentration in groundwater may be controlled by pH mainly.展开更多
The earthqnake emergency material preparation demand analysis can provide the scientific basis for all levels of governments to conduct reasonable and unified configuration of the emergency preparation resources, in o...The earthqnake emergency material preparation demand analysis can provide the scientific basis for all levels of governments to conduct reasonable and unified configuration of the emergency preparation resources, in order to further optimize the earthquake emergency ability construction to provide reference. This paper takes Datong City of Shanxi Province as an example, using the earthquake risk evaluation method, adopting the deterministic method and probabilistic method to conduct earthquake danger analysis, combined with the earthquake emergency rescue case and the previous scholars' research achievements, in order to study and analyze the earthquake emergency material preparation demand in different earthquake dangers.展开更多
With the development of higher education in China, the social responsibility undertaken by higher education is becoming more and more obvious and knowledge innovation in universities, scientific research, teaching and...With the development of higher education in China, the social responsibility undertaken by higher education is becoming more and more obvious and knowledge innovation in universities, scientific research, teaching and others have played an important role for social and economic development. And the agent and practitioner of all the nature and content of these are teachers in universities and colleges which are the main power of education, teaching and research. Highly qualified team of teachers have an important value for higher education. New mode of higher education has also undergone a significant change from denotative growth gradually to connotative development concerning over personnel training and teaching quality, which bring up more requirements for the quality and ability of university teachers. Thus we will put forward a comprehensive analysis of how to comply with cormotative development and come up with new strategy of teachers' pro fessional development.展开更多
Charcoals collected from the middle-late Pliocene sediments of the Taigu Basin,Shanxi Province,China,have been identified as Ulmus sp.(Ulmaceae),Prunus sp.,Maloidoxylon sp.(Rosaceae),and Maclura sp.(Moraceae).These ta...Charcoals collected from the middle-late Pliocene sediments of the Taigu Basin,Shanxi Province,China,have been identified as Ulmus sp.(Ulmaceae),Prunus sp.,Maloidoxylon sp.(Rosaceae),and Maclura sp.(Moraceae).These taxa,along with the previously known fossils,indicate the occurrence of temperate climate and local wildfire at that time.Charcoals of trees and/or shrubs and the morphological changes of these charcoals demonstrate that crown fires and surface fires occurred in the Taigu Basin during the middle-late Pliocene.展开更多
Peperites are special kinds of volcaniclastic materials generated by mingling of magma and unconsolidated sediments. They directly demonstrate the contemporaneity of volcanism and sedimentation, and hence they can be ...Peperites are special kinds of volcaniclastic materials generated by mingling of magma and unconsolidated sediments. They directly demonstrate the contemporaneity of volcanism and sedimentation, and hence they can be used to constrain the local paleoenvironments during volcanic eruptions. We identified peperites in the lower sequence of the northwest outcrops(Inggan-Kalpin area) of Permian Tarim large igneous province(TLIP), Northwest China. In Inggan, blocky peperites were observed at the base of lava flows generated in the second eruption phase. This kind of peperites is generated by quenching of magma in a brittle fragmentation mechanism. While in Kalpin, both the second and the fourth eruption phases preserved peperites in the base of lava flows. Not only blocky but also fluidal peperites can be observed in Kalpin. The fluidal peperites were generated in vapor films, which insulated the magmas from cold sediments and avoided direct thermal shock, and therefore kept the fluidal forms of magma. All of these peperites are hosted by submarine carbonates. In lava sequences generated in the same eruption phases but located in Kaipaizileike, ~15 km east to Inggan, terrestrial flood basalts developed while peperites are absent, implying a paleoenvironmental transition between Kaipaizileike and Inggan-Kalpin area. Gathering information from observed peperites, TLIP lava flows, and the Lower Permian sedimentary strata, we precisely constrained the spatial distribution and temporal evolution of sedimentary facies of the early stage of TLIP. As a result, two marine transgressions were identified. The first transgression occurred contemporaneous with the second eruption phase. The transition from submarine to subaerial is located between Kaipaizileike and Inggan. The second transgression occurred contemporaneous with the forth eruption phase, and the transition from submarine to subaerial occurred between Inggan and Kalpin.展开更多
基金Supported by National Natural Science Foundation of China(40961004,40761027)Guangxi Natural Science Foundation(2011jjA50016)+1 种基金Guangxi Philosophy and Social Science Research Project of 11th Five-Year Plan(06FJY023)Key Laboratory Funds of Ministry of Education(B3G1110)~~
文摘Damp-heat karst mountainous areas are unique areas in terms of socialeconomic development, resource endowment and eco-environment in China, where natural resources are abundant,unique and diverse. However, fragile eco-environment, undeveloped economy and culture, and conflict of human and environment should not be ignored. In the research, a framework of integration of resource-development and environment-protection in damp-heat karst was designed on basis of resource and environment integration, which was applied to Daxin County in Guangxi Province. Furthermore, some integration models were proposed, including integration of development of characteristic agricultural resources and protection of eco-environment, integration of development of manganese ore resources and protection of eco-environment, integration of development of tourism resources and protection of ecoenvironment and integration of development of clean energy and protection of eco-environment.
基金Projects 20076051, G1999022101, and 98029016 supported by National Natural Science Foundation of China, the Special Found for Major State BasicResearch Project, and Research Found for the Doctoral Program of Higher Education
文摘Datong coal was extracted with CS2, n-hexane, benzene, methanol, acetone, tetrahydro-furan(THF) and THF/methanol(1:3,v/v) mixed solvent sequentially. The extracts were analyzed with GC/MS. It is presented that group seperation of soluble organic compounds in the coal can be achieved by fractionated extraction using different solvents. The results show that CS2 was effective for extracting arenes from the coal sample, n-Hexane extractable fraction from Datong coal mainly consists of n-alkanes. A great variety of oxygen-containing compounds are dominant in the components of methanol-soluble fraction. Acyclic isoprenoids, pentecyclic triterpanes and a series of cyclohexanes with long-chain alkyl-substitutes are detected in acetone-soluble fraction. Dicyclic aramatic hydrocarbons are identified in benzene-soluble fraction and 4-6 cyclic condensed aramatic hydrocarbons are identified in THF-soluble fraction. The molecular structures detection of 1,2-dichlorobenzene, 2,4-dibromophnol, 2,4,6-tribromophenol and 4-chlorobenzophenone firstly provide information for existence form of bromine and chlorine in coal.
基金supported by Financial Project of the Beijing Municipal Financial Bureau (No. PXM2008_ 178305_06995)the Pilot Project of the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX2-YW-Q11-03)the 100 Talents Program (Aerosol Characteristics and Its Climatic Impact) of the Chinese Academy of Sciences
文摘Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE). Analysis of the observation data showed that particle pollution was heavy in winter at Datong and that concentrations of most elements were high in the coarse range. Factor analysis (FA) results indicated that the soil and dust, coal combustion dust, and industry dust are main sources for atmospheric particles in winter at Datong. The enrichment factors of element concentrations showed that particle pollution at Datong impacts the down-wind region-Beijing-in the dust season.
基金This work was funded by the National Natural Science Foundation of China[grant numbers 42088101 and 41730964]an Innovation Group Project of the Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)[grant number 311021001].
文摘The dominant patterns of the winter(December-February)surface air temperature anomalies(SATAs)over Central Asia(CA)are investigated in this study.The first two leading modes revealed by empirical orthogonal function(EOF)analysis represent the patterns by explaining 74%of the total variance.The positive phase of EOF1 is characterized by a monopole pattern,corresponding to cold SATAs over CA,while the positive phase of EOF2 shows a meridional dipole pattern with warm and cold SATAs over northern and southern CA.EOF1 is mainly modulated by the negative phase of the Arctic Oscillation(AO)in the troposphere,and the negative AO phase may be caused by the downward propagation of the precursory anomalies of the stratospheric polar vortex.EOF2 is mainly influenced by the Ural blocking pattern and the winter North Atlantic Oscillation(NAO).The SATAs associated with EOF2 can be attributed to a dipole-like pattern of geopotential height anomalies over CA.The dipole-like pattern is mainly caused by the Ural blocking pattern,and the NAO can also contribute to the northern part of the dipole.
基金supported by the U.S.National Science Foundation under contract No.0207466.
文摘Measurements of seafloor asymmetry at about 360 000 pairs of conjugate points along 1250 profiles across the mid-Atlantic Ridge (MAR) provide new constraints on models for the upwelling of the buoyant asthenosphere. The sign and amplitude of the asymmetry vary systematically and are functions of the distance between the spreading center and the location of the inferred location of maximum regional buoyancy (LMRB) in the asthenosphere. The LMRB is a smooth line derived from the observed asymmetry and is more centered at the regional topographic high than the spreading center. These observations are best explained by active upwelling of the underlying buoyant asthenosphere rather than by pressure-release melting.
基金Supported by a grant from the key Scientific Foundation of Shanxi Province (No. 051096-2)
文摘Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. Methods: Fifty patients with advanced NSCLC (stages III to IV), who had received therapies in our Center (Department of Biotherapy, Affiliated to Cancer Hospital of Shanxi Medical University, Taiyuan, China) from August 2008 to January 2010, were treated by DC-CIK + chemotherapy as the combined treatment group; fifty advanced NSCLC patients treated with chemotherapy at the same time served as controls. The immunologic function, short-term therapeutic effects, the 1-year survival rate, the life quality, the chemotherapy side effects were compared between the two groups, the safety and therapeutic effects of DC-CIK cells therapy were observed too. Results: There was no obvious change of subsets of T cells in peripheral blood before and after therapy in DC-CIK + chemotherapy group, and IFN-γ was improved after therapy in this group (P < 0.05); in chemotherapy alone group, the ratios of CD3+CD4+, CD3+CD8+, CD3-CD56+ cells and the secretion of IL-2, TNF-α decreased significantly after therapy (P < 0.05); the ratios of CD3+CD8+, CD3+CD56+ were improved after cell culture (P < 0.05). The disease control rate (DCR) of DC-CIK + chemotherapy group was higher than that in the chemotherapy alone group (78.0% vs 56.0%, P < 0.05); the 1-year survival rates of DC-CIK + chemotherapy group and chemotherapy alone group were 50% and 44% respectively, had no significant difference. Compared with chemotherapy alone group, the occurrence of chemotherapy side effects (including bone marrow suppression, nausea and vomiting, peripheral nerve toxicity) was less in the DC-CIK + chemotherapy group (P < 0.05). The physical and appetite were better in DC-CIK + chemotherapy group after therapy. Conclusion: To compare with simple chemotherapy, DC-CIK + chemotherapy for advanced NSCLC is safe and effective, and it can improve patients' life quality and remission rate, and prolong their survival time.
文摘The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Province and tried to find the generation mechanisms of current non-balanced economic development of Shandong Province.And then approaches to regional development were put forward according to the theory of regional development pattern as a whole.
基金Projects(40972220,40873030) supported by the National Natural Science Foundation of ChinaProject(0991024) supported by the Special Project for Applied Basic Research of Guangxi,China
文摘The issues of acid mine drainage (AMD) and heavy metals contamination in the metal sulfide mine in the add district were explored, through studying the acidification and the heavy metals distribution and evolution of groundwater in the black swan (BS) nickel sulfide mine (Western Australia). The groundwater samples were collected from the drilling holes situated in the vicinity of tailings storage facility (TSF) and in the background of the mine (away from TSF), respectively, and the pH and electric conductivity (Ec) were measured in site and the metal contents were analysed by ICP-MS and ICP-AES, quarterly in one hydrological year. The results disclose that the TSF groundwater is remarkably acidified (.pHmean=5, pHmin=3), and the average contents of heavy metals (Co, Cu, Zn, Cd) and Al, Mn are of 1-2 orders of magnitude higher in TSF groundwater than in background groundwater. It may be due to the percolation of tailings waste water from miU process, which leads the tailings to oxidize and the deep groundwater to acidify and contaminate with heavy metals. Besides, the heavy metals concentration in groundwater may be controlled by pH mainly.
文摘The earthqnake emergency material preparation demand analysis can provide the scientific basis for all levels of governments to conduct reasonable and unified configuration of the emergency preparation resources, in order to further optimize the earthquake emergency ability construction to provide reference. This paper takes Datong City of Shanxi Province as an example, using the earthquake risk evaluation method, adopting the deterministic method and probabilistic method to conduct earthquake danger analysis, combined with the earthquake emergency rescue case and the previous scholars' research achievements, in order to study and analyze the earthquake emergency material preparation demand in different earthquake dangers.
文摘With the development of higher education in China, the social responsibility undertaken by higher education is becoming more and more obvious and knowledge innovation in universities, scientific research, teaching and others have played an important role for social and economic development. And the agent and practitioner of all the nature and content of these are teachers in universities and colleges which are the main power of education, teaching and research. Highly qualified team of teachers have an important value for higher education. New mode of higher education has also undergone a significant change from denotative growth gradually to connotative development concerning over personnel training and teaching quality, which bring up more requirements for the quality and ability of university teachers. Thus we will put forward a comprehensive analysis of how to comply with cormotative development and come up with new strategy of teachers' pro fessional development.
基金supported by National Natural Science Foundation of China(Grant Nos.30770148,30990241,30530050,39770046 and 41072022)
文摘Charcoals collected from the middle-late Pliocene sediments of the Taigu Basin,Shanxi Province,China,have been identified as Ulmus sp.(Ulmaceae),Prunus sp.,Maloidoxylon sp.(Rosaceae),and Maclura sp.(Moraceae).These taxa,along with the previously known fossils,indicate the occurrence of temperate climate and local wildfire at that time.Charcoals of trees and/or shrubs and the morphological changes of these charcoals demonstrate that crown fires and surface fires occurred in the Taigu Basin during the middle-late Pliocene.
基金supported by the National Natural Science Foundation of China(Grant No.41272239)the State Science and Technology Major Project(Grant No.2011ZX05009-001)
文摘Peperites are special kinds of volcaniclastic materials generated by mingling of magma and unconsolidated sediments. They directly demonstrate the contemporaneity of volcanism and sedimentation, and hence they can be used to constrain the local paleoenvironments during volcanic eruptions. We identified peperites in the lower sequence of the northwest outcrops(Inggan-Kalpin area) of Permian Tarim large igneous province(TLIP), Northwest China. In Inggan, blocky peperites were observed at the base of lava flows generated in the second eruption phase. This kind of peperites is generated by quenching of magma in a brittle fragmentation mechanism. While in Kalpin, both the second and the fourth eruption phases preserved peperites in the base of lava flows. Not only blocky but also fluidal peperites can be observed in Kalpin. The fluidal peperites were generated in vapor films, which insulated the magmas from cold sediments and avoided direct thermal shock, and therefore kept the fluidal forms of magma. All of these peperites are hosted by submarine carbonates. In lava sequences generated in the same eruption phases but located in Kaipaizileike, ~15 km east to Inggan, terrestrial flood basalts developed while peperites are absent, implying a paleoenvironmental transition between Kaipaizileike and Inggan-Kalpin area. Gathering information from observed peperites, TLIP lava flows, and the Lower Permian sedimentary strata, we precisely constrained the spatial distribution and temporal evolution of sedimentary facies of the early stage of TLIP. As a result, two marine transgressions were identified. The first transgression occurred contemporaneous with the second eruption phase. The transition from submarine to subaerial is located between Kaipaizileike and Inggan. The second transgression occurred contemporaneous with the forth eruption phase, and the transition from submarine to subaerial occurred between Inggan and Kalpin.