Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of eukaryotic gene expression. Exercise ...Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of eukaryotic gene expression. Exercise training alters the expression levels of large amounts ofmiRNAs in the heart. In addition, circulating miRNAs appear to be regulated by exercise training. In this review, we will summarize recent advances in the regulation of miRNAs during physical exercise intervention in various cardiovascular diseases, including pathologic cardiac hypertrophy, myocardial fibrosis, ischemia-reperfusion injury, myocardial infarction, and heart failure. The regulatory role of circulating miRNAs after exercise training was also reviewed. In conclusion, miRNAs might be a valuable target for treatment of cardiovascular diseases and have great potential as biomarkers for assessment of physical performance.2018 Published by Elsevier B.V.on behalf of Shanghai University of Sport. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).展开更多
This paper presents a new online incremental training algorithm of Gaussian mixture model (GMM), which aims to perform the expectation-maximization(EM) training incrementally to update GMM model parameters online ...This paper presents a new online incremental training algorithm of Gaussian mixture model (GMM), which aims to perform the expectation-maximization(EM) training incrementally to update GMM model parameters online sample by sample, instead of waiting for a block of data with the sufficient size to start training as in the traditional EM procedure. The proposed method is extended from the split-and-merge EM procedure, so inherently it is also capable escaping from local maxima and reducing the chances of singularities. In the application domain, the algorithm is optimized in the context of speech processing applications. Experiments on the synthetic data show the advantage and efficiency of the new method and the results in a speech processing task also confirm the improvement of system performance.展开更多
Tuo Shan Yan Dam is a small darn which was built above Yinjiang River at the Yinjiang Town, Ningbo City, Zhejiang Province of China in 833 AD, but it is greatly contributed to Ningbo City, a current big port city of C...Tuo Shan Yan Dam is a small darn which was built above Yinjiang River at the Yinjiang Town, Ningbo City, Zhejiang Province of China in 833 AD, but it is greatly contributed to Ningbo City, a current big port city of China. The dam and the matched system had become a key hydro-infrastructure to the city's existence and development, and irrigation of the countryside nearby the city from ninth century up to 1987, a big dam was built at upper reach to control water of the river. Tuo Shan Yan Dam functioned an important role in the local water management and met a series of purposes perfectly, mainly as: (a) regulation of the river water; (b) save the flood; (c) stop the salinization; (d) urban water supply; (e) storage of flesh water; (f) irrigation; (g) ship transportation. And it is a miracle that it has been functioned for more than one thousand years. This dam also influenced the local social life and people's spiritual world simultaneously. The construction of the dam and its matched hydro-system is in line with the Chinese ancient logic of urban water management to manage river to meet a multi-proposes of urban development by a key project and a systemic engineering design. It is an important case for better understanding of ancient Chinese urban water management and to learn from the history for current water sustainability. Accordingly, the dam's design, construction and its influence on the local societies are studied in this article.展开更多
Students' Outward bound is widely implemented, the universities have been gradually recognized the significant value in students' Outward bound training in the application of innovative talents. Liaoning University ...Students' Outward bound is widely implemented, the universities have been gradually recognized the significant value in students' Outward bound training in the application of innovative talents. Liaoning University of Engineering and Technology put Students ' Quality Education around the training objectives, so that students develop the quality of credit, and to make it components into personnel training program as a school teaching programs in comprehensive education, the approach is adapted to the innovative training objectives and requirements. In this paper, according to Liaoning Technical University' s implementation of the Outward botmd League credits of practice, we discuss the cognitive development of students' quality and effect, and describe the important role of the Outward bound in cultivating innovative talents.展开更多
This invited paper reviews recent initiatives in teaching about randomized field trials at the graduate level in education research. Reports in a book on randomized trials by Mosteller and Boruch are used as a benchma...This invited paper reviews recent initiatives in teaching about randomized field trials at the graduate level in education research. Reports in a book on randomized trials by Mosteller and Boruch are used as a benchmark. The initiatives have been driven heavily by recent governmental emphasis on "evidence based policy" in education, criminology, welfare and other sectors. This policy has been backed, in the US at least, by substantial investments in mounting randomized controlled trials to evaluate curriculum packages and programs in grades K-12, crime prevention programs, welfare, and other work. Accelerated growth in randomized trials has entailed cross discipline pre-doctoral and post-doctoral institutes and graduate education programs aimed at enhancing the quality in trial design, execution, and analysis of results. Specific illustrations of graduate education in this area of statistics are taken mainly from experience at the University of Pennsylvania's Graduate School of Education and selected other institutions.展开更多
The Church of Kidane Mehret stands at 2,450 m above sea level, close to the village of Sen'afe, on the border between Ethiopia and Eritrea. Probably built in the fifteenth or sixteenth century, the church gradually b...The Church of Kidane Mehret stands at 2,450 m above sea level, close to the village of Sen'afe, on the border between Ethiopia and Eritrea. Probably built in the fifteenth or sixteenth century, the church gradually became a ruin in the middle of the last century. Following the intervention of the monks of this church, a restoration program was set up in 2006. With the agreement of the National Museum in Asmara and the World Monuments Fund, funding was collected together by the German Embassy, the French Embassy, and the Alliance Fran^aise of Asmara, which made it possible to restore the church, between 2006 and 2008. Teams of workmen and women were created to this end. Only traditional techniques were employed for the masonry of the walls, the wooden roofing the plastering, and the interior paintwork. This project, which conforms to the Charter of Venice, could serve as an example for similar restorations in the region and as a model for professional training. Finally, a trilingual article (English, German, and Tigrinya) was published in the Collection "Cultures et Patrimoines d'ErythrGe", 2009.展开更多
Objective: To explore the best remedies for cerebral palsy with aphasia. Methods: A total of 76 cases of cerebral palsy children with aphasia were evenly randomized into control group and treatment group. Patients o...Objective: To explore the best remedies for cerebral palsy with aphasia. Methods: A total of 76 cases of cerebral palsy children with aphasia were evenly randomized into control group and treatment group. Patients of treatment group were treated with “consciousness-restoring needling” plus linguistic training and these of control group treated with simple linguistic training method. Acupuncture was given once every other day, and linguistic training conducted once 6 times a week, with 10 times being a therapeutic course and the interval between two weeks being 10 - 15 days. Following 3 courses of treatment, the therapeutic effect was analyzed. Results. After 3 courses of treatment, of the two 38 cases in treatment and control groups, 27 (71.1% ) and 13 (34.2%) had remarkable improvement in their symptoms. The therapeutic effect of treatment group was significantly superior to that of control group (P 〈 0.01 ). The developmental quotient values of speech of treatment and control groups were 56.36 ± 19.77 and 46.96± 15.63 respectively, displaying that acupuncture could significantly improve cerebral palsy patients' speaking ability (P〈0 05). Conclusion. The therapeutic effect of acupuncture therapy plus linguistic training is significantly superior to that of simple linguistic training .展开更多
The aim of this study is to evaluate the ability of physical training in the maintenance of muscle strength in rats with HFD (high-fat diet) after OVX (ovariectomy). Eighty Wistar rats are at eight weeks of age an...The aim of this study is to evaluate the ability of physical training in the maintenance of muscle strength in rats with HFD (high-fat diet) after OVX (ovariectomy). Eighty Wistar rats are at eight weeks of age and weight 200 g which divided into 8 groups (n = 10) and treated for 12 weeks: GA: OVX + ND (normal diet), GB: OVX + ND + training, GC: sham + ND, GD: sham + ND + training, GE: OVX + HFD, GF: OVX + HFD + training, GG: sham + HFD and GH: sham + HFD + training. HFD consists of standard ration for rats with addition of 30% lipids. In training groups, physical training five training/week was conducted on a treadmill with adaptation period of three weeks up to 18 m/s for one hour, training were performed for 12 weeks. The sedentary animals remained in individual box. To analyze the effects of training and diet, tensile strength tests of the gastrocnemius muscles were conducted: the speed of 0.1 mm/min. Analysis of variance was performed to compare groups. The mean (SD) obtained for the maximum load (N) were: GA 57.77 (6.89), GB 62.74 (5.07), GC 49.45 (6.06), GD 59.42 (5.26) and GE 55.58 (4.72), GF 62.50 (4.56), GG 58.35 (4.54) and GH 56.67 (5.87), respectively. There were no differences for maximum load between surgeries (p = 0.004) and between treatments (p = 0.000). Differences were found also for the relationship surgery diet treatment (p = 0.007). For the variable stiffness (N/mm), there were not statistically significant differences: GA 5.03 (0.72), GB 5.08 (1.09), GC 5.17 (0.53), GD 5.35 (0.80), GE 5.52 (1.20), GF 5.36 (1.07), GG 4.83 (1.03) and GH 5.40 (0.73). For the toughness (N/mm), there were differences between treatments (p = 0.010) and the ratio diet treatment (p = 0.024): GA 455.00 (107.21), GB 541.96 (126.80), GC 394.97 (84.67), GD 566.90 (157.07); GE 424.63 (113.03), GF 478.07 (106.03); GG 517.44 (98.65) and GH 481.26 (129.45). OVX causes decrease in muscle maximum load; exercise treadmill provides increased muscular endurance, regardless of the diet and the OVX in groups, the increased resistance observed in the groups submitted to HFD can result in weight gain associated with the presence estrogen.展开更多
In order to foster an innovative spirit and ability of high-quality talent, much student research training program in domestic universities will incorporate innovative talent training plan. However, the evaluation mec...In order to foster an innovative spirit and ability of high-quality talent, much student research training program in domestic universities will incorporate innovative talent training plan. However, the evaluation mechanism existing research training program is still not perfect for college students, this article has been carrying out a more in-depth discussion and proposes research training program evaluation system for university students.展开更多
Institutional support is an essential antecedent for lecturer's preparedness for e-learning. The purpose of this study was to determine the influence of institutional support through appropriate training programs and...Institutional support is an essential antecedent for lecturer's preparedness for e-learning. The purpose of this study was to determine the influence of institutional support through appropriate training programs and budgetary allocation on lecturers' preparedness for e-learning at the University of Nairobi. A cross-sectional survey design was applied to source data from 212 lecturers and 96 administrative staff. Both quantitative and qualitative techniques were applied to process, analyze, and interpret the data. Quantitative analysis yielded descriptive statistics as well as cross tabulations with Chi-square (x^2) statistic. The study found lack of significant relationship between lecturer's preparedness for e-learning and knowledge of the existence of an Information and Communication Technology (ICT) training program. The existing training program was still underdeveloped in terms of funding and strategies. Lecturers' preparedness for e-learning was also not significantly associated with perceived effectiveness of the existing training program; but was significantly related to training in software tools, as well as the source of funding for training. Although a team of ICT experts has been mandated to help academic staff prepare for e-learning, the team's functionality was constrained by under-funding and multiple roles. Lecturer's preparedness for e-learning also significantly associated with perceived adequacy of budgetary allocation for ICT program at the departmental level. Under-funding was a key factor constraining access to computers at the workplace, reliable internet connectivity and timely technical support, all of which significantly associated with lecturers' preparedness for e-learning. Universities in resource-poor settings should consider creating necessary partnerships to create avenues for information and resource sharing, revamp existing training programs with fmancial and human resources, create linkages with funding institutions, as well as improve budgetary allocation to ensure universal access to functional computers at the workplace, reliable internet connectivity and timely technical support.展开更多
This paper analyzes attention theory in the cognitive psychology and introduces second language vocabulary acquisition. The filter theory and attention resource theory in the attention theory points out that attention...This paper analyzes attention theory in the cognitive psychology and introduces second language vocabulary acquisition. The filter theory and attention resource theory in the attention theory points out that attention has a key effect on the learner's cognitive vocabulary learning by raising students' expectations for new words, by increasing the frequency of exposure to them, by enhancing their perceptual salience, and by increasing the task demand for word study. The fact proves that enhancing attention in input could promote students' vocabulary acquisition and help them form efficient vocabulary learning strategy suitable for their levels of proficiency.展开更多
基金supported by grants from the National Natural Science Foundation of China(81722008,91639101,and81570362 to JX and 81800358 to LW)the Innovation Program of Shanghai Municipal Education Commission(2017-01-07-00-09-E00042 to JX)+1 种基金the Science and TechnologyCommission of Shanghai Municipality(17010500100 to JX)the development fund for Shanghai talents(to JX)
文摘Exercise training is beneficial to the cardiovascular system. MicroRNAs (miRNAs, miRs) are a class of conserved non-coding RNAs and play a wide-ranging role in the regulation of eukaryotic gene expression. Exercise training alters the expression levels of large amounts ofmiRNAs in the heart. In addition, circulating miRNAs appear to be regulated by exercise training. In this review, we will summarize recent advances in the regulation of miRNAs during physical exercise intervention in various cardiovascular diseases, including pathologic cardiac hypertrophy, myocardial fibrosis, ischemia-reperfusion injury, myocardial infarction, and heart failure. The regulatory role of circulating miRNAs after exercise training was also reviewed. In conclusion, miRNAs might be a valuable target for treatment of cardiovascular diseases and have great potential as biomarkers for assessment of physical performance.2018 Published by Elsevier B.V.on behalf of Shanghai University of Sport. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).
文摘This paper presents a new online incremental training algorithm of Gaussian mixture model (GMM), which aims to perform the expectation-maximization(EM) training incrementally to update GMM model parameters online sample by sample, instead of waiting for a block of data with the sufficient size to start training as in the traditional EM procedure. The proposed method is extended from the split-and-merge EM procedure, so inherently it is also capable escaping from local maxima and reducing the chances of singularities. In the application domain, the algorithm is optimized in the context of speech processing applications. Experiments on the synthetic data show the advantage and efficiency of the new method and the results in a speech processing task also confirm the improvement of system performance.
文摘Tuo Shan Yan Dam is a small darn which was built above Yinjiang River at the Yinjiang Town, Ningbo City, Zhejiang Province of China in 833 AD, but it is greatly contributed to Ningbo City, a current big port city of China. The dam and the matched system had become a key hydro-infrastructure to the city's existence and development, and irrigation of the countryside nearby the city from ninth century up to 1987, a big dam was built at upper reach to control water of the river. Tuo Shan Yan Dam functioned an important role in the local water management and met a series of purposes perfectly, mainly as: (a) regulation of the river water; (b) save the flood; (c) stop the salinization; (d) urban water supply; (e) storage of flesh water; (f) irrigation; (g) ship transportation. And it is a miracle that it has been functioned for more than one thousand years. This dam also influenced the local social life and people's spiritual world simultaneously. The construction of the dam and its matched hydro-system is in line with the Chinese ancient logic of urban water management to manage river to meet a multi-proposes of urban development by a key project and a systemic engineering design. It is an important case for better understanding of ancient Chinese urban water management and to learn from the history for current water sustainability. Accordingly, the dam's design, construction and its influence on the local societies are studied in this article.
文摘Students' Outward bound is widely implemented, the universities have been gradually recognized the significant value in students' Outward bound training in the application of innovative talents. Liaoning University of Engineering and Technology put Students ' Quality Education around the training objectives, so that students develop the quality of credit, and to make it components into personnel training program as a school teaching programs in comprehensive education, the approach is adapted to the innovative training objectives and requirements. In this paper, according to Liaoning Technical University' s implementation of the Outward botmd League credits of practice, we discuss the cognitive development of students' quality and effect, and describe the important role of the Outward bound in cultivating innovative talents.
文摘This invited paper reviews recent initiatives in teaching about randomized field trials at the graduate level in education research. Reports in a book on randomized trials by Mosteller and Boruch are used as a benchmark. The initiatives have been driven heavily by recent governmental emphasis on "evidence based policy" in education, criminology, welfare and other sectors. This policy has been backed, in the US at least, by substantial investments in mounting randomized controlled trials to evaluate curriculum packages and programs in grades K-12, crime prevention programs, welfare, and other work. Accelerated growth in randomized trials has entailed cross discipline pre-doctoral and post-doctoral institutes and graduate education programs aimed at enhancing the quality in trial design, execution, and analysis of results. Specific illustrations of graduate education in this area of statistics are taken mainly from experience at the University of Pennsylvania's Graduate School of Education and selected other institutions.
文摘The Church of Kidane Mehret stands at 2,450 m above sea level, close to the village of Sen'afe, on the border between Ethiopia and Eritrea. Probably built in the fifteenth or sixteenth century, the church gradually became a ruin in the middle of the last century. Following the intervention of the monks of this church, a restoration program was set up in 2006. With the agreement of the National Museum in Asmara and the World Monuments Fund, funding was collected together by the German Embassy, the French Embassy, and the Alliance Fran^aise of Asmara, which made it possible to restore the church, between 2006 and 2008. Teams of workmen and women were created to this end. Only traditional techniques were employed for the masonry of the walls, the wooden roofing the plastering, and the interior paintwork. This project, which conforms to the Charter of Venice, could serve as an example for similar restorations in the region and as a model for professional training. Finally, a trilingual article (English, German, and Tigrinya) was published in the Collection "Cultures et Patrimoines d'ErythrGe", 2009.
文摘Objective: To explore the best remedies for cerebral palsy with aphasia. Methods: A total of 76 cases of cerebral palsy children with aphasia were evenly randomized into control group and treatment group. Patients of treatment group were treated with “consciousness-restoring needling” plus linguistic training and these of control group treated with simple linguistic training method. Acupuncture was given once every other day, and linguistic training conducted once 6 times a week, with 10 times being a therapeutic course and the interval between two weeks being 10 - 15 days. Following 3 courses of treatment, the therapeutic effect was analyzed. Results. After 3 courses of treatment, of the two 38 cases in treatment and control groups, 27 (71.1% ) and 13 (34.2%) had remarkable improvement in their symptoms. The therapeutic effect of treatment group was significantly superior to that of control group (P 〈 0.01 ). The developmental quotient values of speech of treatment and control groups were 56.36 ± 19.77 and 46.96± 15.63 respectively, displaying that acupuncture could significantly improve cerebral palsy patients' speaking ability (P〈0 05). Conclusion. The therapeutic effect of acupuncture therapy plus linguistic training is significantly superior to that of simple linguistic training .
文摘The aim of this study is to evaluate the ability of physical training in the maintenance of muscle strength in rats with HFD (high-fat diet) after OVX (ovariectomy). Eighty Wistar rats are at eight weeks of age and weight 200 g which divided into 8 groups (n = 10) and treated for 12 weeks: GA: OVX + ND (normal diet), GB: OVX + ND + training, GC: sham + ND, GD: sham + ND + training, GE: OVX + HFD, GF: OVX + HFD + training, GG: sham + HFD and GH: sham + HFD + training. HFD consists of standard ration for rats with addition of 30% lipids. In training groups, physical training five training/week was conducted on a treadmill with adaptation period of three weeks up to 18 m/s for one hour, training were performed for 12 weeks. The sedentary animals remained in individual box. To analyze the effects of training and diet, tensile strength tests of the gastrocnemius muscles were conducted: the speed of 0.1 mm/min. Analysis of variance was performed to compare groups. The mean (SD) obtained for the maximum load (N) were: GA 57.77 (6.89), GB 62.74 (5.07), GC 49.45 (6.06), GD 59.42 (5.26) and GE 55.58 (4.72), GF 62.50 (4.56), GG 58.35 (4.54) and GH 56.67 (5.87), respectively. There were no differences for maximum load between surgeries (p = 0.004) and between treatments (p = 0.000). Differences were found also for the relationship surgery diet treatment (p = 0.007). For the variable stiffness (N/mm), there were not statistically significant differences: GA 5.03 (0.72), GB 5.08 (1.09), GC 5.17 (0.53), GD 5.35 (0.80), GE 5.52 (1.20), GF 5.36 (1.07), GG 4.83 (1.03) and GH 5.40 (0.73). For the toughness (N/mm), there were differences between treatments (p = 0.010) and the ratio diet treatment (p = 0.024): GA 455.00 (107.21), GB 541.96 (126.80), GC 394.97 (84.67), GD 566.90 (157.07); GE 424.63 (113.03), GF 478.07 (106.03); GG 517.44 (98.65) and GH 481.26 (129.45). OVX causes decrease in muscle maximum load; exercise treadmill provides increased muscular endurance, regardless of the diet and the OVX in groups, the increased resistance observed in the groups submitted to HFD can result in weight gain associated with the presence estrogen.
文摘In order to foster an innovative spirit and ability of high-quality talent, much student research training program in domestic universities will incorporate innovative talent training plan. However, the evaluation mechanism existing research training program is still not perfect for college students, this article has been carrying out a more in-depth discussion and proposes research training program evaluation system for university students.
文摘Institutional support is an essential antecedent for lecturer's preparedness for e-learning. The purpose of this study was to determine the influence of institutional support through appropriate training programs and budgetary allocation on lecturers' preparedness for e-learning at the University of Nairobi. A cross-sectional survey design was applied to source data from 212 lecturers and 96 administrative staff. Both quantitative and qualitative techniques were applied to process, analyze, and interpret the data. Quantitative analysis yielded descriptive statistics as well as cross tabulations with Chi-square (x^2) statistic. The study found lack of significant relationship between lecturer's preparedness for e-learning and knowledge of the existence of an Information and Communication Technology (ICT) training program. The existing training program was still underdeveloped in terms of funding and strategies. Lecturers' preparedness for e-learning was also not significantly associated with perceived effectiveness of the existing training program; but was significantly related to training in software tools, as well as the source of funding for training. Although a team of ICT experts has been mandated to help academic staff prepare for e-learning, the team's functionality was constrained by under-funding and multiple roles. Lecturer's preparedness for e-learning also significantly associated with perceived adequacy of budgetary allocation for ICT program at the departmental level. Under-funding was a key factor constraining access to computers at the workplace, reliable internet connectivity and timely technical support, all of which significantly associated with lecturers' preparedness for e-learning. Universities in resource-poor settings should consider creating necessary partnerships to create avenues for information and resource sharing, revamp existing training programs with fmancial and human resources, create linkages with funding institutions, as well as improve budgetary allocation to ensure universal access to functional computers at the workplace, reliable internet connectivity and timely technical support.
文摘This paper analyzes attention theory in the cognitive psychology and introduces second language vocabulary acquisition. The filter theory and attention resource theory in the attention theory points out that attention has a key effect on the learner's cognitive vocabulary learning by raising students' expectations for new words, by increasing the frequency of exposure to them, by enhancing their perceptual salience, and by increasing the task demand for word study. The fact proves that enhancing attention in input could promote students' vocabulary acquisition and help them form efficient vocabulary learning strategy suitable for their levels of proficiency.