Glycine soja or wild soybean is the wild ancestor of the soybean, being an important source for property improvement and variety breeding. With abundant wild soybeans, their habitat is undermining, and wild soybeans a...Glycine soja or wild soybean is the wild ancestor of the soybean, being an important source for property improvement and variety breeding. With abundant wild soybeans, their habitat is undermining, and wild soybeans are facing increasing- ly threatened in Shandong if measures are not taken yet. Besides, wild soybean germplasm is far from further exploiting or using. The research analyzed status quo and problems of wild soybean germplasm posed countermeasures or suggestions in crop germplasm conservation and use. resources conservation and use and pro- order to provide references for agricultural crop germplasm conservation and use.展开更多
Tangjiashan landslide is a typical high-speed consequent landslide of medium-steep dip angle. This landslide triggered by earthquake took place in about semi-minute. The relative sliding displacement is 900 meters, so...Tangjiashan landslide is a typical high-speed consequent landslide of medium-steep dip angle. This landslide triggered by earthquake took place in about semi-minute. The relative sliding displacement is 900 meters, so average sliding speed is about 30 meters per second. The longitudinal length of barrier dam which is formed by high-speed landslide along river is 803.4 meters; and maximum width crossing river is 611.8 meters. And its volume is estimated about 20.37 million steres. Through detailed geological investigation of the barrier dam, together with early geological information before earthquake, geological structures of the barrier dam and its stability of upstream and downstream slopes are studied when water level reaches different elevations in condition of continual after shocks with seismic intensity of 7 or 8 Richter scale. On this basis, dam-breaking mode of barrier dam is discussed deeply. Thereby, analytic results provide significant guidance and advices to front headquarters of Tangjiashan barrier dam, so that some proper engineering measures can be implemented and flood discharge can be carried out well.展开更多
Karenia mikimotoi (Miyake & Kominami ex Oda) Hansen & Moestrup is associated with harmful algal blooms in temperate and subtropical zones of the world. The hemolytic substances produced by K. mikimotoi are thought...Karenia mikimotoi (Miyake & Kominami ex Oda) Hansen & Moestrup is associated with harmful algal blooms in temperate and subtropical zones of the world. The hemolytic substances produced by K. mikimotoi are thought to cause mortality in fishes and invertebrates. We evaluated the composition of the hemolytic toxin produced by K. mikimotoi cultured in the laboratory using thin-layer chromatography. In addition, we evaluated the effect of co-occuring algae (Prorocentrum donghaiense and Alexandrium tamarense) and the cladoceran grazer Moina mongoliea on hemolytic toxin production in K. mikimotoi. The hemolytic toxins from K. mikimotoi were a mixture of 2 liposaccharides and 1 lipid. Waterborne clues from P. donghaiense and A. tamarense inhibited the growth of K. mikimotoi but increased the production of hemolytic toxins. Conversely, K. mikimotoi strongly inhibited the growth of caged P. donghaiense and A. tamarense. In addition, the ingestion of K. mikimotoi by M. mongolica induced the production of hemolytic toxins in K. mikimotoi. Taken together, our results suggest that the presence of other microalgae and grazers may be as important as environmental factors for controlling the production of hemolytic substances. K. mikimotoi secreted allelochemicals other than unstable fatty acids with hemolytic activity. The production of hemolytic toxins in dinofiagellates was not only dependent on resource availability, but also on the risk of predation. Hemolytic toxins likely play an important role as chemical deterrents secreted by K. mikimotoi.展开更多
Geomorphological mapping plays a key role in landscape representation: it is the starting point for many applications and for the realization of thematic maps, such as hazard and risk maps, geoheritage and geotourism ...Geomorphological mapping plays a key role in landscape representation: it is the starting point for many applications and for the realization of thematic maps, such as hazard and risk maps, geoheritage and geotourism maps. Traditional geomorphological maps are useful for scientific purposes but they need to be simplified for different aims as management and education. In tourism valorization, mapping of geomorphological resources(i.e., geosites, and geomorphosites), and of geomorphic evidences of past hazardous geomorphological events, is important for increasing knowledge about landscape evolution and active processes, potentially involving geomorphosites and hiking trails. Active geomorphosites, as those widespread in mountain regions, testify the high dynamicity of geomorphic processes and their link with climatic conditions. In the present paper, we propose a method to produce and to update cartographic supports(Geomorphological Boxes)realized starting from a traditional geomorphological survey and mapping. The Geomorphological Boxes are geomorphological representation of single, composed or complex landforms drawn on satellite images, using the official Italian geomorphological legend(ISPRA symbols). Such cartographic representation is also addressed to the analysis(identification, evaluation and selection) of Potential Geomorphosites and Geotrails. The method has been tested in the upper portion of the Loana Valley(Western Italian Alps), located within the borders of the Sesia Val Grande Geopark, recognized by UNESCO in 2013. The area has a good potential for geotourism and for educational purposes. We identified 15 Potential Geomorphosites located along 2 Geotrails; they were ranked according to specific attributes also in relation with a Reference Geomorphosite located in the Loana hydrographic basin and inserted in official national and regional databases of geosites(ISPRA; Regione Piemonte). Finally, the ranking of Potential Geomorphosites allowed to select the most valuable ones for valorization or geoconservation purposes. In thisframework, examples of Geomorphological Boxes are proposed as supports to geo-risk education practices.展开更多
Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE)...Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE). Analysis of the observation data showed that particle pollution was heavy in winter at Datong and that concentrations of most elements were high in the coarse range. Factor analysis (FA) results indicated that the soil and dust, coal combustion dust, and industry dust are main sources for atmospheric particles in winter at Datong. The enrichment factors of element concentrations showed that particle pollution at Datong impacts the down-wind region-Beijing-in the dust season.展开更多
Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small...Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. Methods: Fifty patients with advanced NSCLC (stages III to IV), who had received therapies in our Center (Department of Biotherapy, Affiliated to Cancer Hospital of Shanxi Medical University, Taiyuan, China) from August 2008 to January 2010, were treated by DC-CIK + chemotherapy as the combined treatment group; fifty advanced NSCLC patients treated with chemotherapy at the same time served as controls. The immunologic function, short-term therapeutic effects, the 1-year survival rate, the life quality, the chemotherapy side effects were compared between the two groups, the safety and therapeutic effects of DC-CIK cells therapy were observed too. Results: There was no obvious change of subsets of T cells in peripheral blood before and after therapy in DC-CIK + chemotherapy group, and IFN-γ was improved after therapy in this group (P < 0.05); in chemotherapy alone group, the ratios of CD3+CD4+, CD3+CD8+, CD3-CD56+ cells and the secretion of IL-2, TNF-α decreased significantly after therapy (P < 0.05); the ratios of CD3+CD8+, CD3+CD56+ were improved after cell culture (P < 0.05). The disease control rate (DCR) of DC-CIK + chemotherapy group was higher than that in the chemotherapy alone group (78.0% vs 56.0%, P < 0.05); the 1-year survival rates of DC-CIK + chemotherapy group and chemotherapy alone group were 50% and 44% respectively, had no significant difference. Compared with chemotherapy alone group, the occurrence of chemotherapy side effects (including bone marrow suppression, nausea and vomiting, peripheral nerve toxicity) was less in the DC-CIK + chemotherapy group (P < 0.05). The physical and appetite were better in DC-CIK + chemotherapy group after therapy. Conclusion: To compare with simple chemotherapy, DC-CIK + chemotherapy for advanced NSCLC is safe and effective, and it can improve patients' life quality and remission rate, and prolong their survival time.展开更多
Jadeite quartzite, essentially a two-phase rock made up of jadeite and quartz, is one of the most important UHP lithologies occur- ring in the Dabie Mountain ultrahigh pressure metamorphic belt and forms layers in bio...Jadeite quartzite, essentially a two-phase rock made up of jadeite and quartz, is one of the most important UHP lithologies occur- ring in the Dabie Mountain ultrahigh pressure metamorphic belt and forms layers in biotite-plagioclase gneiss. High pressure- high temperature studies on natural albite from the country rock gneiss were undertaken to reveal the--in parts----complex mineralogical changes that occur in the jadeite quartzite during prograde metamorphism. Experiments were conducted at 800- 1200~C, in the pressure range of 2.0-3.5 GPa. One of the most intriguing results shows that the low pressure boundary of the jadeite+coesite stability field is located between about 3.2 GPa at 1000~C and 3.4 GPa at 1200~C, thus about (0.2-0.3)_+0.1 GPa higher than the quartz-coesite transition curve, given the uncertainty in the present study. Minor amounts of sodium and aluminum entering the structure of quartz and the intimate intergrowth texture of the run products may contribute to the ob- served pressure shift. Combined petrological and mineralogical studies on the run products and the natural rocks yield the fol- lowing prograde reaction sequence to have occurred: The protolith of the jadeite- quartzite from Dabie Mountain is an albitized siltstone/greywacke characterized by an albite+quartz assemblage. During prograde metamorphism albite breaks down to form jadeite+quartz and thus at this stage two types of quartz can be distinguished whereas type-I-quartz already existed in the pro- tolith, type-II-quartz represents a newly formed reaction product of albite. During further P-T-increase the pure type- I-quartz was transformed to coesite, whereas type-II-quartz (together with jadeite) was still present as a stable phase because of its im- purities of Na and A1. At a later stage during further subduction, type-II-quartz also decomposes to form coesite. These studies represent an important puzzlement for a better understanding of the evolution of jadeite- quartzite from the Dabie Mountain during continental crust subduction and thus contribute to a more complete knowledge of the formation of the Dabie Mountain UHP orogenic belt in general.展开更多
基金Supported by National Science&Technology Pillar Program during the Twelfth Fiveyear Plan Period(2013BAD01B0106)Sub-platform in Shandong Province of National Infrastructure of Plant Germplasm Resources(NICGR2015/2016-032)+2 种基金Shandong Provicne Modern Agricultural Technology System Coarse Cereals Innovation Team(SDAIT-15-01)Youth Foundation of Shandong Academy of Agricultural Sciences(2016YQN19)Agricultural Science&Technology Innovation Program of Shandong Academy of Agricultural Sciences(CXGC2016A02/A12)~~
文摘Glycine soja or wild soybean is the wild ancestor of the soybean, being an important source for property improvement and variety breeding. With abundant wild soybeans, their habitat is undermining, and wild soybeans are facing increasing- ly threatened in Shandong if measures are not taken yet. Besides, wild soybean germplasm is far from further exploiting or using. The research analyzed status quo and problems of wild soybean germplasm posed countermeasures or suggestions in crop germplasm conservation and use. resources conservation and use and pro- order to provide references for agricultural crop germplasm conservation and use.
基金funding from the National Natural Science Foundation Project (Grant No. 40772175, 40972175)the Scientific research fund of Southwest Jiaotong University (Grant No.2008-A01)+1 种基金the Opening Fund of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection (Chengdu University of Technology) (Grant No. DZKJ–08012)the National Natural Science Foundation Project-mutual fund of Yunnan Province (Grant No.U1033601)
文摘Tangjiashan landslide is a typical high-speed consequent landslide of medium-steep dip angle. This landslide triggered by earthquake took place in about semi-minute. The relative sliding displacement is 900 meters, so average sliding speed is about 30 meters per second. The longitudinal length of barrier dam which is formed by high-speed landslide along river is 803.4 meters; and maximum width crossing river is 611.8 meters. And its volume is estimated about 20.37 million steres. Through detailed geological investigation of the barrier dam, together with early geological information before earthquake, geological structures of the barrier dam and its stability of upstream and downstream slopes are studied when water level reaches different elevations in condition of continual after shocks with seismic intensity of 7 or 8 Richter scale. On this basis, dam-breaking mode of barrier dam is discussed deeply. Thereby, analytic results provide significant guidance and advices to front headquarters of Tangjiashan barrier dam, so that some proper engineering measures can be implemented and flood discharge can be carried out well.
基金Supported by the National Natural Science Foundation of China(Nos.30970502,U0733006)the National Basic Research Program of China(973 Program)(No.2010CB428702)
文摘Karenia mikimotoi (Miyake & Kominami ex Oda) Hansen & Moestrup is associated with harmful algal blooms in temperate and subtropical zones of the world. The hemolytic substances produced by K. mikimotoi are thought to cause mortality in fishes and invertebrates. We evaluated the composition of the hemolytic toxin produced by K. mikimotoi cultured in the laboratory using thin-layer chromatography. In addition, we evaluated the effect of co-occuring algae (Prorocentrum donghaiense and Alexandrium tamarense) and the cladoceran grazer Moina mongoliea on hemolytic toxin production in K. mikimotoi. The hemolytic toxins from K. mikimotoi were a mixture of 2 liposaccharides and 1 lipid. Waterborne clues from P. donghaiense and A. tamarense inhibited the growth of K. mikimotoi but increased the production of hemolytic toxins. Conversely, K. mikimotoi strongly inhibited the growth of caged P. donghaiense and A. tamarense. In addition, the ingestion of K. mikimotoi by M. mongolica induced the production of hemolytic toxins in K. mikimotoi. Taken together, our results suggest that the presence of other microalgae and grazers may be as important as environmental factors for controlling the production of hemolytic substances. K. mikimotoi secreted allelochemicals other than unstable fatty acids with hemolytic activity. The production of hemolytic toxins in dinofiagellates was not only dependent on resource availability, but also on the risk of predation. Hemolytic toxins likely play an important role as chemical deterrents secreted by K. mikimotoi.
基金funded by the Fondi Potenziamento della Ricerca - Linea 2 - 2015 Project "Dynamic of active margins: from rift to collisional chains", leader Dr. Davide Zanoni
文摘Geomorphological mapping plays a key role in landscape representation: it is the starting point for many applications and for the realization of thematic maps, such as hazard and risk maps, geoheritage and geotourism maps. Traditional geomorphological maps are useful for scientific purposes but they need to be simplified for different aims as management and education. In tourism valorization, mapping of geomorphological resources(i.e., geosites, and geomorphosites), and of geomorphic evidences of past hazardous geomorphological events, is important for increasing knowledge about landscape evolution and active processes, potentially involving geomorphosites and hiking trails. Active geomorphosites, as those widespread in mountain regions, testify the high dynamicity of geomorphic processes and their link with climatic conditions. In the present paper, we propose a method to produce and to update cartographic supports(Geomorphological Boxes)realized starting from a traditional geomorphological survey and mapping. The Geomorphological Boxes are geomorphological representation of single, composed or complex landforms drawn on satellite images, using the official Italian geomorphological legend(ISPRA symbols). Such cartographic representation is also addressed to the analysis(identification, evaluation and selection) of Potential Geomorphosites and Geotrails. The method has been tested in the upper portion of the Loana Valley(Western Italian Alps), located within the borders of the Sesia Val Grande Geopark, recognized by UNESCO in 2013. The area has a good potential for geotourism and for educational purposes. We identified 15 Potential Geomorphosites located along 2 Geotrails; they were ranked according to specific attributes also in relation with a Reference Geomorphosite located in the Loana hydrographic basin and inserted in official national and regional databases of geosites(ISPRA; Regione Piemonte). Finally, the ranking of Potential Geomorphosites allowed to select the most valuable ones for valorization or geoconservation purposes. In thisframework, examples of Geomorphological Boxes are proposed as supports to geo-risk education practices.
基金supported by Financial Project of the Beijing Municipal Financial Bureau (No. PXM2008_ 178305_06995)the Pilot Project of the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX2-YW-Q11-03)the 100 Talents Program (Aerosol Characteristics and Its Climatic Impact) of the Chinese Academy of Sciences
文摘Atmospheric particle samples were collected at an urban site of Datong, Shanxi Province, during December 2004 and their element concentrations at different sizes were analyzed by particle-induced X-ray emission (PIXE). Analysis of the observation data showed that particle pollution was heavy in winter at Datong and that concentrations of most elements were high in the coarse range. Factor analysis (FA) results indicated that the soil and dust, coal combustion dust, and industry dust are main sources for atmospheric particles in winter at Datong. The enrichment factors of element concentrations showed that particle pollution at Datong impacts the down-wind region-Beijing-in the dust season.
基金Supported by a grant from the key Scientific Foundation of Shanxi Province (No. 051096-2)
文摘Objective: The aim of the study was to evaluate the safety and therapeutic effects of autologous dendritic cells co-cultured with cytokine-induced killer cells (DC-CIK) combined with chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. Methods: Fifty patients with advanced NSCLC (stages III to IV), who had received therapies in our Center (Department of Biotherapy, Affiliated to Cancer Hospital of Shanxi Medical University, Taiyuan, China) from August 2008 to January 2010, were treated by DC-CIK + chemotherapy as the combined treatment group; fifty advanced NSCLC patients treated with chemotherapy at the same time served as controls. The immunologic function, short-term therapeutic effects, the 1-year survival rate, the life quality, the chemotherapy side effects were compared between the two groups, the safety and therapeutic effects of DC-CIK cells therapy were observed too. Results: There was no obvious change of subsets of T cells in peripheral blood before and after therapy in DC-CIK + chemotherapy group, and IFN-γ was improved after therapy in this group (P < 0.05); in chemotherapy alone group, the ratios of CD3+CD4+, CD3+CD8+, CD3-CD56+ cells and the secretion of IL-2, TNF-α decreased significantly after therapy (P < 0.05); the ratios of CD3+CD8+, CD3+CD56+ were improved after cell culture (P < 0.05). The disease control rate (DCR) of DC-CIK + chemotherapy group was higher than that in the chemotherapy alone group (78.0% vs 56.0%, P < 0.05); the 1-year survival rates of DC-CIK + chemotherapy group and chemotherapy alone group were 50% and 44% respectively, had no significant difference. Compared with chemotherapy alone group, the occurrence of chemotherapy side effects (including bone marrow suppression, nausea and vomiting, peripheral nerve toxicity) was less in the DC-CIK + chemotherapy group (P < 0.05). The physical and appetite were better in DC-CIK + chemotherapy group after therapy. Conclusion: To compare with simple chemotherapy, DC-CIK + chemotherapy for advanced NSCLC is safe and effective, and it can improve patients' life quality and remission rate, and prolong their survival time.
基金supported by the Research Projects of China(Grants Nos.2009CB825003,41002068)the State Key Laboratory of GPMR(Grant No.MSF-GPMR 200911)China University of Geosciences(Grant No.CUGL090204)
文摘Jadeite quartzite, essentially a two-phase rock made up of jadeite and quartz, is one of the most important UHP lithologies occur- ring in the Dabie Mountain ultrahigh pressure metamorphic belt and forms layers in biotite-plagioclase gneiss. High pressure- high temperature studies on natural albite from the country rock gneiss were undertaken to reveal the--in parts----complex mineralogical changes that occur in the jadeite quartzite during prograde metamorphism. Experiments were conducted at 800- 1200~C, in the pressure range of 2.0-3.5 GPa. One of the most intriguing results shows that the low pressure boundary of the jadeite+coesite stability field is located between about 3.2 GPa at 1000~C and 3.4 GPa at 1200~C, thus about (0.2-0.3)_+0.1 GPa higher than the quartz-coesite transition curve, given the uncertainty in the present study. Minor amounts of sodium and aluminum entering the structure of quartz and the intimate intergrowth texture of the run products may contribute to the ob- served pressure shift. Combined petrological and mineralogical studies on the run products and the natural rocks yield the fol- lowing prograde reaction sequence to have occurred: The protolith of the jadeite- quartzite from Dabie Mountain is an albitized siltstone/greywacke characterized by an albite+quartz assemblage. During prograde metamorphism albite breaks down to form jadeite+quartz and thus at this stage two types of quartz can be distinguished whereas type-I-quartz already existed in the pro- tolith, type-II-quartz represents a newly formed reaction product of albite. During further P-T-increase the pure type- I-quartz was transformed to coesite, whereas type-II-quartz (together with jadeite) was still present as a stable phase because of its im- purities of Na and A1. At a later stage during further subduction, type-II-quartz also decomposes to form coesite. These studies represent an important puzzlement for a better understanding of the evolution of jadeite- quartzite from the Dabie Mountain during continental crust subduction and thus contribute to a more complete knowledge of the formation of the Dabie Mountain UHP orogenic belt in general.