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革兰氏阴性菌脓毒血症患者早期CD4阳性淋巴细胞和NK细胞的临床研究 被引量:2
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作者 高学军 聂大平 张晓录 《中国误诊学杂志》 CAS 2007年第23期5453-5455,共3页
目的:明确革兰氏阴性菌脓毒血症患者淋巴细胞和NK细胞的早期变化以及血清可溶性粒细胞靶受体(sTREM-1)的水平,探讨脓毒血症患者早期的免疫状况。方法:脓毒血症发生后12h内,采集39例高度怀疑革兰氏阴性菌感染患者的外周血;同样采集16个... 目的:明确革兰氏阴性菌脓毒血症患者淋巴细胞和NK细胞的早期变化以及血清可溶性粒细胞靶受体(sTREM-1)的水平,探讨脓毒血症患者早期的免疫状况。方法:脓毒血症发生后12h内,采集39例高度怀疑革兰氏阴性菌感染患者的外周血;同样采集16个健康人的血样品。应用单克隆抗体在流式细胞仪上分析淋巴细胞及NK细胞;血清sTREM-1的浓度用ELISA法测定。结果:与对照相比,脓毒血症患者CD3/CD4细胞明显减少(P<0.01);而NK细胞明显增高(P<0.01)。患者ANNEXIN-V/CD4/CD3阳性细胞、ANNEXIN-V/CD8/CD3阳性细胞以及ANNEXIN-V/CD14阳性细胞比例(中位数±标准差)分别是(7.53±2.25)%、(7.59±3.39)%和(1.96±4.17)%。脓毒血症患者血清sTREM-1水平较对照明显增高(P<0.01)。结论:研究结果首次证实革兰氏阴性菌脓毒血症患者早期出现CD4淋巴细胞减少、NK细胞增加和血清sTREM-1水平增高的免疫特征。 展开更多
关键词 毒血症/病因学/代谢 革兰氏阴性菌感染/并发症/代谢 CD4淋巴细胞计数 杀伤细胞 天然/代谢 膜糖蛋白类/血液 受体 免疫/血液 人类
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Mobilization of Phosphorus by Naturally Occurring Or-ganic Acids in Oxisols and Ultisols 被引量:8
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作者 HANXING-GUO C.F.JORDAN 《Pedosphere》 SCIE CAS CSCD 1995年第4期289-303,共15页
Citric and malic acids at concentrations of 0.1, 1.0, 10, and 100 mmol/L were added to three Ultisolsand one Oxisol. The amount of P in solution increased with increasing organic acid concentrations, while theaniount ... Citric and malic acids at concentrations of 0.1, 1.0, 10, and 100 mmol/L were added to three Ultisolsand one Oxisol. The amount of P in solution increased with increasing organic acid concentrations, while theaniount of Fe- and Al-bound P decreased. This result suggested that naturally occurring products of organicmatter decomposition could increase the P availability to plants in soils where there is a relatively large poolof Fe- and Al-bound P.The interactions between citric and malic acids at the above concentrations. and P added at rates of10, 20, 40, and 80 mg/kg were determined. At zero levels of organic acids, all added P became either labileor bound, and greater proportions remained soluble as the concentration of organic acids increased, whichsuggested that organic acids reduced fixation of dissolved P in Fe- and AI-rich soils.Agricultural practices which increase organic matter input on P-deficient acid soiIs could decrease Pdeficiency. This would be important in many tropical and subtropical regions where these soils are common,and where the costs of fertilizers and lime are relatively high. 展开更多
关键词 acid soils adsorption CHELATION phosphorous mobilization SOLUBILIZATION
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Symbionts, a promising source of bioactive natural products 被引量:2
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作者 Xuan Zhang Wei Wei Renxiang Tan 《Science China Chemistry》 SCIE EI CAS CSCD 2015年第7期1097-1109,共13页
Symbionts are microorganisms residing in multicellular hosts(e.g., plants and animals), and they have been witnessed to be a rich source of diverse functional molecules. This review describes structures and biological... Symbionts are microorganisms residing in multicellular hosts(e.g., plants and animals), and they have been witnessed to be a rich source of diverse functional molecules. This review describes structures and biological activities of symbiont-derived secondary metabolites commonly referred to as "natural products", and highlights that symbiotic microbes represent an underexplored reservoir of natural products with unique scaffolds and promising significance in managing human healthcare and agricultural production. 展开更多
关键词 SYMBIONTS natural products BIOACTIVITIES
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